Insulin research points way to better type 1 diabetes treatments

by Anil Kumar



New research that significantly improves our understanding of how insulin interacts with cells in the human body is published today. The study could have major implications for the development of treatments for Type I diabetes.

By developing and analysing a range of super active insulins, scientists from the York Structural Biology Laboratory at the University of York have been able to identify common features that point to the likely molecular structure of human insulin when it is active in the body.

The research also offers new insight into how insulin binds to insulin receptors on cells.

The research was conducted with colleagues at the Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic, and is published in the journal Proceedings of the National Academy of Sciences.

Dr Marek Brzozowski, from the York Structural Biology Laboratory, said: "The structures of inactive forms of insulin and the insulin receptor are reasonably well known, but documenting how they interact has proven to be a considerable scientific challenge.

"Improving our understanding of this interaction holds the key to developing far more sophisticated treatments for Type I diabetes and this research represents an important step forward."

The research could help the development of insulin treatments that can be more carefully controlled or that could be delivered without the need for injections.


(Anil Kumar -- sub-editor compiled and published Insulin research points way to better type 1 diabetes treatments at HealthNewsTrack on January 26, 2010 sourced from University of York - http://www.york.ac.uk/)

Diabetes - recent articles and current news stories:

- Gestational diabetes and poverty increased ADHD risk in offspring
- Low calorie diet improves heart function in diabetic obese patients
- Neural stem cell transplant may cure diabetes
- Diabetes increases risk of dementia and Alzheimer's disease
- Red meat increases type 2 diabetes risk

Diabetes article/news source:

Read more health articles from University of York and health articles from UK.

Diabetes - search related terms:

Diabetes, Diabetes mellitus, Human insulin, Insulin, Type 1 diabetes,
Diabetes books,

Searched keywords: diabetes (29), diabetes type 2 (10), fda (7),

Subscribe to Health News by Email

List health news, Health organizations, Health news world, Glossary, Best health articles, Featured     Go to top

The information provided on Health Newstrack is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician. We comply with the HONcode principles for trustworthy health information, and Health News Track is hon code accredited, verify here.
About us, Site map Privacy policy, Disclaimer
© 2007, 2008, 2009, 2010, 2011 HealthNewsTrack.com
3.2