Pesticides, chemicals, vitamin E linked to diabetes
Researchers at the Stanford University School of Medicine suggests that one should begin looking suspiciously at other aspects of life - like past exposure to certain pesticides or chemicals and even one form of vitamin E. This may lead to diabetes.
In fact, the association of some of these so-called "environmental" cues with diabetes surpasses that of the best genetic markers scientists have identified for the disease.
In this new study, the scientists relied instead on an unconventional approach that treats environmental variables as "genes." That conceptual shift allowed them to use some of the same techniques initially developed to identify the many sections of DNA throughout the genome that might contribute to disease development. Bioinformatics expert Atul Butte, MD, PhD, assistant professor of pediatric cancer biology, compared the data generated by the new approach to the amount and types of information gleaned from a DNA microarray.
"This approach catapults us from being forced to ask very simple, directed questions about environment and disease into a new realm in which we can look at many, many variables simultaneously and without bias," said Butte, who is also director of the Center for Pediatric Bioinformatics at Lucile Packard Children's Hospital. "In the future, we'll be able to analyze the effect of genes and environment together, to find, perhaps, that a specific gene increases the risk of a disease only if the person is also drinking polluted well water."
Specifically, in this study, Butte and his coworkers used the technique to identify a previously known association between people with type-2 diabetes and a class of organic compounds called polychlorinated biphenyls, or PCBs, commonly used for many applications until the late 1970s. They also uncovered a strong, but unexpected, relationship between diabetes and high levels of a form of vitamin E called gamma-tocopherol, which is prevalent in fruits, vegetables, nuts and milk.
The scientists are careful to caution, however, that an association doesn't necessarily mean that vitamin E or pollutants cause type-2 diabetes, and that more research is needed to fully understand these complex relationships.
(Anil Kumar -- sub-editor compiled and published Pesticides, chemicals, vitamin E linked to diabetes
at HealthNewsTrack on May 22, 2010 sourced from Stanford University Medical Center - http://med-www.stanford.edu/)
Diabetes - recent articles and current news stories:
- Low birth weight African American women having higher incidence of type 2 diabetes
- Dexcom's G4 Platinum continuous glucose monitoring system approved for kids
- Chocolate, tea and berries may protect from diabetes
- Omega 3 fatty acids reduce type 2 diabetes risk
- Diabetes duration and advancing age independently predict diabetes complications
Most related articles:
- Pesticides, chemicals, vitamin E linked to diabetes
- Environmental pollution can cause diabetes
- Parkinson's disease linked to pesticide exposure
- Environmental chemicals in breast milk may cause testicular cancer later
- Vitamin E increases tuberculosis risk in smokers
More related articles:
- Pesticide, Chemical, Vitamin E, Diabetes, Type 2 diabetes, Insulin
- Youth with type 1 diabetes linked to insulin resistance
- 3 new drugs approved for type 2 diabetes in US
- Link between obesity and diabetes discovered
- Insulin research points way to better type 1 diabetes treatments
- Frog secretions offer diabetes treatment hope
Diabetes related articles:
- New diabetes risk assessment developed
- Preventing kidney disease in diabetes may prolong life
- One person diagnosed with diabetes every three minutes
- Nicole Johnson takes action for type 1 diabetes research
- Lilly donated Insulin to International Diabetes Federation's Life for a Child Program
Diabetes article/news source:
Read more health articles from Stanford University Medical Center
and health articles from USA
Diabetes - search related terms:Chemical
, Type 2 diabetes
, Vitamin E
Health Newstrack is dedicated to serve recent and updated health & medical research, events/news, views/reviews to its subscribers and free access to general public, health & medical professionals, and other health seekers worldwide online with a user-friendly system.
New associations between diabetes, environmental factors found by novel Stanford analytic technique
What is Diabetes?
About Diabetes -- Diabetes mellitus is a condition in which the pancreas no longer produces enough insulin or when cells stop responding to the insulin that is produced, so that glucose in the blood cannot be absorbed into the cells of the body. Symptoms include frequent urination, lethargy, excessive thirst, and hunger. The treatment includes changes in diet, oral medications, and in some cases, daily injections of insulin.