Alzheimer's Disease

Alzheimer's disease (AD) is the most common form of dementia, a neurologic disease characterized by loss of mental ability severe enough to interfere with normal activities of daily living, lasting at least six months, and not present from birth. AD usually occurs in old age, and is marked by a decline in cognitive functions such as remembering, reasoning, and planning.

Alzheimer's Disease - most related articles:

- Cell phone may boost memory in Alzheimer's disease patients - 4.4
- Alzheimer's Society comment on benefits of weekly curry - 4.2
- Depression may increase Alzheimer's disease risk - 4.1
- Protein regulates enzyme linked to Alzheimer's disease - 4.1
- Potential Alzheimer's disease diagnostic test using spinal fluid - 4.1
- People with early Alzheimer's disease may have lower BMI - 4
- Test your memory test for Alzheimer's disease - 4
- Brain imaging findings in Alzheimer's disease associated with genetic factors - 4
- Alcohol consumption may protect against Alzheimer's Disease - 3.9
- Statins, cholesterol lowering drugs may not prevent Alzheimer's Disease - 3.9

Alzheimer's Disease articles

Brain stimulating habits lowers Alzheimer's disease risk
Individuals who keep their brains active throughout life with cognitively stimulating activities such as reading, writing and playing games appear to have reduced levels of the ß-amyloid protein, which is the major part of the amyloid plaque in Alzheimer disease.

People with early Alzheimer's disease may have lower BMI
People in the earliest stages of Alzheimer's disease are more likely to have a lower body mass index (BMI). A new study examined 506 people with advanced brain imaging techniques and analyses of cerebrospinal fluid to look for biomarkers for Alzheimer's disease, which can be present years before the first symptoms begin.

Blood test may detect Alzheimer's Disease progression
Researchers found a way to predict how quickly patients with Alzheimer's disease (AD) will lose cognitive function by looking at ratios of two fatty compounds in their blood.

Diabetes increases risk of dementia and Alzheimer's disease
People with diabetes appear to be at a significantly increased risk of developing dementia, revealed by researchers in a recent study published in Neurology, the medical journal of the American Academy of Neurology.

People seek early diagnosis of Alzheimer's disease
Results of an international survey reveal that over 85% of respondents in the five countries surveyed say that if they were exhibiting confusion and memory loss, they would want to see a doctor to determine if the cause of the symptoms was Alzheimer's disease. Over 94% would want the same if a family member were exhibiting the symptoms.

Memory problems often not present in middle aged people with Alzheimer's disease
A new study suggests more than half of people who develop Alzheimer's disease before the age of 60 are initially misdiagnosed as having other kinds of brain disease when they do not have memory problems.

Potential Alzheimer's disease diagnostic test using spinal fluid
Researchers at the University of Kentucky are working on a potential diagnostic test for Alzheimer's disease, based on biomarkers in cerebrospinal fluid.

Brain size predicts dementia in advance in Alzheimer's disease
Subtle differences in brain anatomy among older individuals with normal cognitive skills may be able to predict both the risk of developing Alzheimer's disease in the following decade and how quickly symptoms of dementia would develop.

Gene therapy clearing toxic proteins in brain may prevent Alzheimer's disease
Gene therapy that boosts the ability of brain cells to gobble up toxic proteins prevents development of Alzheimer's disease in mice that are predestined to develop it, report researchers at Georgetown University Medical Center.

Imaging can identify biomarker of alzheimer's disease
Preliminary research suggests that use of a type of molecular imaging procedure may have the ability to detect the presence of beta-amyloid in the brains of individuals during life, a biomarker that is identified during autopsy to confirm a diagnosis of Alzheimer disease.

A new way to test blood for Alzheimer's disease
Using a new technology that relies on thousands of synthetic molecules to fish for disease-specific antibodies, researchers have developed a potential method for detecting Alzheimer's disease with a simple blood test.

See off Alzheimer's disease with purple fruits
Ground-breaking research from Professor Douglas Kell, published in the journal Archives of Toxicology, has found that the majority of debilitating illnesses are in part caused by poorly-bound iron which causes the production of dangerous toxins that can react with the components of living systems.

Mid life cholesterol levels not linked to Alzheimer's disease
Contrary to earlier research, a new, long-term study suggests that cholesterol level in mid-life may not be linked to later development of Alzheimer's disease.

Function found for Alzheimer's protein APP
A new study reveals that when amyloid precursor protein (APP) fails to convert iron from an unsafe form to a safe one for transport or storage, it leads to rise in iron levels inside neurons mount to toxic levels and eventually causes Alzheimer's disease.

Beta amyloid protein spurs formation of Alzheimer's plaques
In Alzheimer's disease, the problem is beta-amyloid, a protein that accumulates in the brain and causes nerve cells to weaken and die. Drugs designed to eliminate plaques made of beta-amyloid have a fatal problem: they need to enter the brain and remove the plaques without attacking healthy brain cells.

Rheumatoid arthritis signaling protein may reverse Alzheimer's disease
A signaling protein released during rheumatoid arthritis dramatically reduced Alzheimer's disease pathology and reversed the memory impairment of mice bred to develop symptoms of the neurodegenerative disease, a new study by the University of South Florida reports.

Depression may double risk of dementia & Alzheimer's disease
A new study shows that having depression may nearly double your risk of developing dementia later in life, revealed in a research published in the July 6, 2010, issue of Neurology.

Brain imaging findings in Alzheimer's disease associated with genetic factors
By investigating the association between genetic loci related to Alzheimer's disease and neuroimaging measures related to disease risk, researchers may have uncovered additional evidence that several previously studied genetic variants are associated with the development and progression of Alzheimer's disease and also may have identified new genetic risk factors for further study, according to a report in the June issue of Archives of Neurology, one of the JAMA/Archives journals.

Apple juice improves behavior but not cognition in Alzheimer's disease patients
Apple juice can be a useful supplement for calming the declining moods that are part of the normal progression of moderate-to-severe Alzheimer's Disease (AD), revealed by researchers.

Mutations in presenilin gene may cause early onset Alzheimer's disease
Researchers have discovered how mutations in the presenilin 1 gene cause early-onset Alzheimer's disease (AD). The finding is reported online in the journal Cell.

Protein regulates enzyme linked to Alzheimer's disease
Researchers at Tufts University School of Medicine have zeroed in on a protein that may play a role in the progression of Alzheimer's disease. The team found that increasing levels of the protein (called GGA3) prevented the accumulation of an enzyme linked to Alzheimer's.

Alcohol consumption may protect against Alzheimer's Disease
A new study published this month in the Journal of Alzheimer's Disease suggests a protective effect of alcohol consumption on the risk of Alzheimer's disease, particularly in women who do not smoke.

Eye test for early detection of Alzheimer's and Down syndrome
Researchers are going to develop an innovative eye test for early detection of Alzheimer's disease and Down syndrome. As they discovered the protein that forms plaques in the brain in Alzheimer's disease also accumulates in the eyes of people with Down syndrome.

Ablation heart procedure reduces risk of Alzheimer and stroke
Researchers found that ablation treatment can eliminate serious risks associated with atrial fibrillation. New research was presented at National Heart Rhythm Society.

Spouses who care for partners with dementia at higher risk of same fate
Husbands or wives who care for spouses with dementia are six times more likely to develop the memory-impairing condition than those whose spouses don't have it, according to results of a 12-year study led by Johns Hopkins, Utah State University, and Duke University.

New gene linked to Alzheimer's disease
Researchers have identified a gene that appears to increase a person's risk of developing late-onset Alzheimer's disease, the most common type of Alzheimer's disease.

Nuts, fish, poultry and fruits reduce Alzheimer's disease risk
Individuals whose diet includes more salad dressing, nuts, fish, poultry and certain fruits and vegetables and fewer high-fat dairy products, red meats, organ meats and butter appear less likely to develop Alzheimer's disease.

Copper may lead to Alzheimer's disease in older
A new study linked high levels of copper and iron to Alzheimer's disease, heart disease, and other age-related disorders. The report is published in ACS' Chemical Research in Toxicology.

Gene variation linked to lower risk of dementia, Alzheimer's disease
Preliminary research suggests that variation of a gene for a plasma protein is associated with slower age-related memory decline and a lower risk of dementia and Alzheimer disease (AD).

Exercise may prevent, improve cognitive impairment
Moderate physical activity performed in midlife or later appears to be associated with a reduced risk of mild cognitive impairment, whereas a six-month high-intensity aerobic exercise program may improve cognitive function in individuals who already have the condition.

Testing gene therapy for Alzheimer's disease
University Hospitals Case Medical Center is one of 12 sites conducting the first Phase 2 clinical trial of a gene therapy for Alzheimer's disease (AD). The study uses a viral-based gene transfer system called CERE-110, which is designed to deliver nerve growth factor (NGF) into the brain.

Cell phone may boost memory in Alzheimer's disease patients
The millions of people who spend hours every day on a cell phone may have a new excuse for yakking. A surprising new study in mice provides the first evidence that long-term exposure to electromagnetic waves associated with cell phone use may actually protect against, and even reverse, Alzheimer's disease.

Preparing for successful aging in the new year 2010
It's never too early or too late to start working toward the goal of improving brain health. So perhaps the New Year is the perfect time to consider how one achieves a long and satisfying life.

High leptin levels may protect against Alzheimer's disease, dementia
Researchers from Boston University School of Medicine (BUSM) have found that higher leptin (a protein that controls weight and appetite) levels were associated with a lower incidence of Alzheimer's Disease (AD) and dementia.

Green tea may help brain disorder patients
Researchers have found that combining two chemicals, one of which is the green tea component EGCG, can prevent and destroy a variety of protein structures known as amyloids. Amyloids are the primary culprits in fatal brain disorders such as Alzheimer's, Huntington's, and Parkinson's diseases.

Reduced muscle strength increases Alzheimer's disease risk
Individuals with weaker muscles appear to have a higher risk for Alzheimer's disease and declines in cognitive function over time, revealed by the researchers.

Extra virgin olive oil prevents Alzheimer's disease
Natural compound, Oleocanthal, in extra virgin olive oil targets toxic beta amyloid proteins in patients with Alzheimer's disease, revealed by US researchers. Extra virgin olive oil contains the highest amount of polyphenol antioxidants also.

Sleep loss may increase Alzheimer's disease
Neurodegenerative disorders like Alzheimer's disease and Parkinson's disease often disrupt sleep. The new researches indicate that sleep loss could play a role in the genesis of such disorders.

Gene therapy may cure Alzheimer's disease
To stop the progression of Alzheimer's disease, scientists are conducting gene therapy trial on patients with a mild form of Alzheimer's Disease in US.

Poor money management indicates Alzheimer's disease
New research finds poor money management skills may indicate that a person with mild memory problems will soon develop Alzheimer's disease, revealed by researchers in a new research study.

Mediterranean diet and exercise lower Alzheimer's disease risk
Both being more physically active and adhering to a Mediterranean-type diet appears to be associated with reduced Alzheimer's risk, according to a new report in the August 12, 2009 issue of the Journal of the American Medical Association (JAMA).

Avian influenza increases Parkinson's disease risk
At least one strain of the H5N1 avian influenza virus leaves survivors at significantly increased risk for Parkinson's disease and possibly other neurological problems later in life, according to new research from St. Jude Children's Research Hospital.

Biomarkers may help predict risk of Alzheimer's disease
Several cerebrospinal fluid (CSF) biomarkers showed good accuracy in identifying patients with mild cognitive impairment who progressed to Alzheimer's disease, revealed by US researchers in JAMA.

Learning about Alzheimer's disease risk cause no distress
Disclosing genetic risk information to adult children of patients with Alzheimer's disease (AD) who request this information does not result in significant short-term psychological distress, revealed by researchers.

White matter changes may predict dementia risk
Elderly people with no memory or thinking problems are more likely to later develop thinking problems if they have a growing amount of "brain rust," or small areas of brain damage, revealed by researchers.

Alzheimer's disease drug treats traumatic brain injury
The destructive cellular pathways activated in Alzheimer's disease are also triggered following traumatic brain injury, say researchers from Georgetown University Medical Center (GUMC).

Alcohol has cognitive benefits in older adults
Moderate alcohol intake offers long-term cognitive protection and reduces the risk of dementia in older adults, revealed by researchers at the Wake Forest University School of Medicine.

Structural MRI may diagnose dementia patients accurately
Researchers developed STAND-Map - a framework for MRI-based differential diagnosis of three common neurodegenerative disorders: Alzheimer's disease, frontotemporal lobar degeneration, and Lewy body disease using Structural MRI.

Intellectual ability test in early 20s may predict dementia risk
People who have superior language skills early in life may be less likely to develop Alzheimer's disease decades later, despite having the hallmark signs of the disease, revealed by researchers.

Nitrate linked to Alzheimer's disease, Diabetes, Parkinson's disease
Increased levels of nitrates in our environment and food increases disease risks including Alzheimer's disease, diabetes mellitus and Parkinson's disease, revealed by researchers.

Dementia research funding must triple, UK
The UK's leading dementia charities united with eminent scientists to urge the government to commit to a national dementia research strategy and triple annual investment to £96 million in five years.

Coffee may reverse Alzheimer's disease
Caffeine significantly decreased abnormal levels of the protein linked to Alzheimer's disease, both in the brains and in the blood of mice exhibiting symptoms of the disease, revealed by researchers.

Depression may increase Alzheimer's disease risk
People with memory problems who are depressed are more likely to develop Alzheimer's disease compared to people who are not depressed, revealed by US researchers.

Test your memory test for Alzheimer's disease
UK researchers at Addenbrooke's Hospital have created a new cognitive test (TYM) that detects Alzheimer's disease quickly and accurately. The study published online on BMJ.com.

Peptide Abeta a new marker for Alzheimer's disease
Researchers in Japan have detected a peptide in cerebrospinal fluid (CSF) that can show whether a person is developing Alzheimer's disease. Measuring the level of this peptide could show that the disease process has started, long before any serious damage is done to the brain.

Cognitive impairment linked to reduced survival in US
Alzheimer's disease and its precursor, mild cognitive impairment, appear to be associated with an increased risk of death among both white and African American older adults according to a new, long-term research study by neurological experts at the Alzheimer's Disease Center at Rush University Medical Center.

Alzheimer's Society comment on new tau tangle research
New research published in Nature Cell Biology suggests that tangle formation can be transferred from one type of trans genetic mouse line to another.

Parkinson's disease linked to pesticide exposure
The cause of Parkinson's disease (PD), the second most frequent neurodegenerative disease after Alzheimer's disease, is unknown, but in most cases it is believed to involve a combination of environmental risk factors and genetic susceptibility.

Alzheimer's Society comment on benefits of weekly curry
Professor Murali Doraiswamy, from the Duke University Medical Center in Carolina, has suggested that curcumin, found in the popular curry ingredient tumeric, could help prevent the onset of dementia.

Heart disorder linked to Alzheimer's disease dementia
Researchers at Intermountain Medical Center in Salt Lake City believe that they have made a breakthrough connection between atrial fibrillation, a fairly common heart rhythm disorder, and Alzheimer's disease, the leading form of dementia among Americans.

Alzheimer's disease risk index predicts Alzheimer's in elderly
A new tool can help predict whether people age 65 and older have a high risk of developing Alzheimer's disease. Research on the tool is published in the May 13, 2009, online issue of Neurology, the medical journal of the American Academy of Neurology.

Alzheimer's disease - most expensive disease, Maria Shriver
Sargent Shriver, an advisor to two presidents and the first director of the Peace Corps, no longer remembers the name of his daughter: Maria, California's first lady and former television reporter. He has Alzheimer's disease.

Pain relievers seem not to prevent Alzheimer's disease
A new study shows that nonsteroidal anti-inflammatory drugs (NSAIDs) such as the pain relievers ibuprofen and naproxen do not prevent Alzheimer's disease, but they may instead delay its onset.

SAP a new therapeutic target in Alzheimer's disease
New therapeutic approaches in Alzheimer's disease are urgently needed. Work led by Professor Mark Pepys FRS over more than 20 years has identified a protein known as serum amyloid P component (SAP) as a possible therapeutic target in Alzheimer's disease.

Male and female brain differences mechanism unfolded
University of Otago researchers have discovered a new mechanism which contributes to subtle differences between male and female brains and behaviours.

A-beta clearance - a key to treatment or prevention of Alzheimer's disease
In Alzheimer's disease the brain accumulates a molecule called A-beta that can be quite toxic to brain cells. Many researchers believe that finding ways to clear A-beta may be a key to treatment or prevention of Alzheimer's disease.

MRI shows brain atrophy pattern that predicts Alzheimer's Disease
Researchers have identified a pattern of regional brain atrophy in patients with mild cognitive impairment (MCI) that indicates a greater likelihood of progression to Alzheimer's disease. Researchers used special MRI methods.

Mediterranean diet improves cognitive impairment in Alzheimer's disease
Eating a Mediterranean diet appears to be associated with less risk of mild cognitive impairment-a stage between normal aging and dementia-or of transitioning from mild cognitive impairment into Alzheimer's disease.

Insulin may slow or prevent Alzheimer's disease
Insulin, by shielding memory-forming synapses from harm, may slow or prevent the damage and memory loss caused by toxic proteins in Alzheimer's disease, reported by researchers at Northwestern University.

NICE's decision on Alzheimer's drugs based on flawed calculations
Thousands of people with early stage Alzheimer's are being denied access to the only drugs for the disease due to fundamental flaws in the way their cost effectiveness has been calculated.

Sleep disorder - an early sign of dementia, Parkinson's disease
People with a sleep disorder that causes them to kick or cry out during their sleep may be at greater risk of developing dementia or Parkinson's disease, revealed by researchers.

Yeast to identify drugs for Alzheimer's disease
CSIRO scientists have developed a new system to screen for compounds that can inhibit one of the processes that takes place during the progression of Alzheimer's disease.

Marijuana reduces memory impairment
The more research they do, the more evidence Ohio State University scientists find that specific elements of marijuana can be good for the aging brain by reducing inflammation there and possibly even stimulating the formation of new brain cells.

Ginkgo biloba does not reduce dementia, Alzheimer's disease risk
The medicinal herb Ginkgo biloba does not reduce the risk of dementia or Alzheimer's disease development in either the healthy elderly or those with mild cognitive impairment, according to a large multicenter trial led by researchers at the University of Pittsburgh School of Medicine.

Secret of sharp memory in old age revealed
Researchers at Northwestern University's Feinberg School of Medicine wondered if the brains of the elderly with still laser sharp memory -- called "super aged" -- were somehow different than everyone else's.

Education level linked to Alzheimer's disease, dementia
Individuals with higher education levels appear to score higher on cognitive tests despite having evidence of brain plaques associated with Alzheimer's disease.

Fatty acids linked to Alzheimer's disease
Scientists at the Gladstone Institute of Neurological Disease (GIND) and the University of California have found that complete or partial removal of an enzyme that regulates fatty acid levels improves cognitive deficits in a mouse model of Alzheimer's disease (AD).

Vitamin B does not slow cognitive decline in Alzheimer's disease
A clinical trial led by Paul S. Aisen, M.D., professor of neurosciences at the University of California, San Diego School of Medicine, showed that high-dose vitamin B supplements did not slow the rate of cognitive decline in patients with mild to moderate Alzheimer disease.

PET scans useful to assess Alzheimer's disease
A type of positron emission tomography (PET) scanning may be useful in a non-invasive assessment of the formation of Alzheimer's disease–related plaques in the brain, according to small study posted online today that will appear in the October 2008 print issue of Archives of Neurology, one of the JAMA/Archives journals.

Living with a partner reduces Alzheimer's disease risk
Living with a spouse or a partner decreases the risk of developing Alzheimer's and other dementia diseases. This according to a study by Krister Håkansson, researcher in psychology at Växjö University and Karolinska Institutet, Sweden. The results were presented for the first time yesterday at the world's largest dementia conference.

Lazy brain - a shrinking brain
People who have been more mentally active over their lives have a larger hippocampus – which relates to memory – and critically that it shrinks at half the rate of those who have lower mental activity.

Exercise may prevent Early Alzheimer's disease
Mild Alzheimer's disease patients with higher physical fitness had larger brains compared to mild Alzheimer's patients with lower physical fitness, according to a study published in the July 15, 2008, issue of Neurology, the medical journal of the American Academy of Neurology.

Invest in a future without dementia, Alzheimer's disease
Alzheimer's Australia released a report 'Australian Dementia Research' that recommends annual funding for dementia research be increased three-fold to $36 million in response to the growing economic and social impact of the dementia epidemic.

Brain maps to assist disease diagnosis, brain surgery
Researchers from the Howard Florey Institute in Melbourne are developing new technology to create individualised brain maps that will revolutionise diagnosis of disease like multiple sclerosis, Parkinson's disease, Alzheimer's disease and Huntington's disease, and enhance the accuracy of brain surgery.

Bapineuzumab promising in treating Alzheimer's disease
Elan Corporation, plc (NYSE: ELN) and Wyeth (NYSE: WYE) announced encouraging preliminary findings from a Phase 2 study of bapineuzumab (AAB-001) in patients with mild to moderate Alzheimer's disease. In the 18-month trial, bapineuzumab appeared to have clinical activity in treating Alzheimer's disease.

Novel approach to treat Alzheimer's disease
JADO Technologies GmbH, the leading developer of RAFT intervention therapeutics, announced the publication of a paper in Science demonstrating a potential novel strategy for therapeutic intervention in Alzheimer's and other diseases by targeting discrete sub-compartments in the cell membrane (RAFTS).

Obesity in midlife increases dementia risk
People in their 40s with larger stomachs have a higher risk for dementia when they reach their 70s, according to a study published in the March 26, 2008, online issue of Neurology, the medical journal of the American Academy of Neurology.

$1 million help to find Alzheimer's disease cure
UK's best-selling author, Terry Pratchett, has pledged $1million to leading UK charity, the Alzheimer's Research Trust, in a bid to help find a cure for the devastating disease, with which he was diagnosed in December 2007.

Memory loss, less common in older Americans
It appears that memory loss and thinking problems are becoming less common among older Americans. A new study shows a downward trend in the rate of "cognitive impairment" - the umbrella term for everything from significant memory loss to dementia and Alzheimer's disease - among people aged 70 and older.

Statins, cholesterol lowering drugs may not prevent Alzheimer's Disease
Taking statins, which are cholesterol-lowering drugs, offers no protection against Alzheimer's disease, revealed by US researchers at Rush University Medical Center in Chicago.

Depressed girls can't smell the roses
Can't smell the roses? Maybe you're depressed. Smell too much like a rose yourself? Maybe you've got the same problem. Scientists from Tel Aviv University recently linked depression to a biological mechanism that affects the olfactory glands. It might explain why some women, without realizing it, wear too much perfume.

White matter disease affects treatment in Alzheimer's disease patients
Researchers at Sunnybrook have shown that there may be a difference in response to treatment in Alzheimer's Disease (AD) patients with and without white matter disease in selective areas of the brain.

Aging brain failures to communicate
A team of Howard Hughes Medical Institute researchers has shown that normal aging disrupts communication between different regions of the brain. The new research, which used advanced medical imaging techniques to look at the brain function of 93 healthy individuals from 18 to 93 years old, shows that this decline happens even in the absence of serious pathologies like Alzheimer's disease.

93 Alzheimer's Disease articles listed above.

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What is Alzheimer's Disease
Alzheimer's disease (AD) is the most common form of dementia, a neurologic disease characterized by loss of mental ability severe enough to interfere with normal activities of daily living, lasting at least six months, and not present from birth. AD usually occurs in old age, and is marked by a decline in cognitive functions such as remembering, reasoning, and planning.

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