Bone

Bone - most related articles:

- Merck's Odanacatib increases bone mineral density - 4.5
- Fat mass helps build bone mass in girls - 4.2
- Bone density related to bone erosion in rheumatoid arthritis patients - 4
- Osteoporosis drugs increase bone necrosis risk - 4
- Bone density unnecessary in women taking osteoporosis drugs - 3.9
- Breast cancer spread stopped by bone drug - 3.8
- HIV infected at higher risk for bone fractures - 3.7
- Obesity may be bad for bone health - 3.7
- Bone marrow cell therapy for ischemic heart disease patients - 3.6
- Dense bones linked to prostate cancer risk - 3.6

Bone articles

Obesity epidemic in United States underestimated
The scope of the obesity epidemic in the United States has been greatly underestimated. Researchers found that the Body Mass Index (BMI) substantially under-diagnoses obesity when compared to the Dual Energy X-ray Absorptiometry (DXA) scan, a direct simultaneous measure of body fat, muscle mass, and bone density.

Vitamin D therapy does not improve heart disease risk
Patients with chronic kidney disease who received the vitamin D compound paricalcitol for up to 48 weeks did not show improvement on measures of cardiac structure, function, or left ventricular mass, compared to patients who received placebo.

Alpharadin improved survival in advanced prostate cancer patients
Until recently, options for patients with bone metastases from advanced prostate cancer have been very limited. But now the first Phase III study of an alpha-pharmaceutical in these patients has shown that it can prolong survival significantly, according to research reported recently at the 2011 European Multidisciplinary Cancer Congress.

Label change expected for osteoporosis drugs Fosamax, Actonel and Boniva
A US FDA advisory committee wants the health agency FDA to limit the duration of bisphosphonate therapy for treatment of osteoporosis. The panel could not agree on what that time limit should be. The panel also endorsed a label change for osteoporosis drugs.

Soy isoflavone tablets not reducing bone loss or menopausal symptoms
Soy isoflavone tablets do not appear to reduce bone loss or menopausal symptoms in women within the first five years of menopause, revealed by researchers recently in a study reported in Archives of Internal Medicine.

Daily intake of Red wine resveratrol good for people with sedentary lifestyles
Resveratrol may be able to prevent the deleterious consequences of sedentary behaviors in humans. Researchers revealed that a daily intake of resveratrol prevents the ill effects of simulated weightlessness on muscle and bone metabolism.

Facial wrinkles may predict bone density in early menopause
In postmenopausal women the appearance of the skin may offer a glimpse of the skeletal well-being, a relationship not previously described, said Lubna Pal, MD, a reproductive endocrinologist and associate professor at Yale School of Medicine, New Haven, Conn. The worse a woman's skin wrinkles are during the first few years of menopause, the lower her bone density is.

Increasing daily calcium will not reduce fracture risk in later life
While moderate amounts of calcium (around 700 mg a day) are vital for maintaining healthy bones, there is no need to start increasing calcium intake in order to reduce the risk of fractures or osteoporosis in later life, finds a paper published in bmj.

HIV infected at higher risk for bone fractures
Low bone mineral density in HIV-infected patients is common and raises concerns about increased risks of fracture, revealed by researchers.

Breast cancer survivors at higher risk for fractures
The combined effects of chemotherapy and endocrine therapy may increase the risk of bone fractures in breast cancer survivors, revealed by researchers in a study.

Drugs for epilepsy increases fracture risk in older
Most anti-epileptic drugs are associated with an increased risk of non-traumatic fracture in individuals 50 years of age and older, revealed by researchers in a study published in the Archives of Neurology.

Dense bones linked to prostate cancer risk
Men who develop prostate cancer, especially the more aggressive and dangerous forms that spread throughout the body, tend to retain denser bones as they age than men who stay free of the disease, suggests new research from Johns Hopkins and the National Institute on Aging (NIA), part of the National Institutes of Health.

Prolia - new injectable osteoporosis treatment for postmenopausal women
The U.S. Food and Drug Administration approved Prolia, an injectable treatment for postmenopausal women with osteoporosis who are at high risk for fractures.

Osteoporosis drugs linked to atypical fractures
Bisphosphonate treatments, proven to enhance bone density and reduce fracture incidence in post-menopausal women, may adversely affect bone quality and increase risk of atypical fractures of the femur when used for four or more years.

Bone marrow can harbor HIV infected cells
University of Michigan scientists have identified a new reservoir for hidden HIV-infected cells that can serve as a factory for new infections. This indicate a new target for curing the disease so those infected with the virus may someday no longer rely on AIDS drugs for a lifetime.

Egyptian pharaoh King Tutankhamun died of malaria
Malaria and bone abnormalities appear to have contributed to the death of Egyptian pharaoh King Tutankhamun, revealed by researchers.

Fat mass helps build bone mass in girls
According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), fat mass is important in increasing bone size and thickness, but this effect appears to be stronger in girls than boys.

New 3 drug combination for multiple myeloma patients
A new three-drug combination has shown in a phase 1/2 clinical trial that it is a "highly effective regimen" in the treatment of patients newly diagnosed with multiple myeloma, a cancer of white blood cells in bone marrow, say researchers from Dana-Farber Cancer Institute.

New stem cell technology for complicated bone fractures
Researchers have developed a new way of using stem cells to provide better and rapid healing for patients suffering from complicated bone fractures.

812 cases of dengue fever in Delhi
Dengue fever has affected more than 800 people in Delhi - capital of India. Health officials confirmed 29 new cases of dengue infection reaching to 812 cases of debgue fever in this season.

Stem cell therapy offers hope for acute lung injury
Adult stem cells from bone marrow can prevent acute lung injury in a mouse model of the disease, revealed by researchers at the University of Illinois at Chicago College of Medicine.

Diabetes may weaken your bones
The inflammatory molecule TNF-a may contribute to delayed bone fracture healing in diabetics, revealed by researchers. Diabetes, a condition where the body either does not produce enough, or respond to, insulin, affects at least 171 million people worldwide, a figure that is likely to double by 2030.

US children low in vitamin D
Seven out of ten U.S. children have low levels of vitamin D, raising their risk of bone and heart disease, according to a study of over 6,000 children by researchers at Albert Einstein College of Medicine of Yeshiva University.

Osteoporosis drug may improve immune system
An osteoporosis drug zoledronic acid (Reclast) proven to save lives after hip fractures may do so by strengthening the body's immune system, revealed by geriatrics researchers at Duke University Medical Center.

Bone density related to bone erosion in rheumatoid arthritis patients
A new study has examined the relationship between two rheumatoid arthritis related processes i.e. focal erosions and osteoporosis, in the hopes of providing insight into the underlying pathophysiology of RA-related bone disease.

Breast cancer's ability to relapse linked to genes
New research led by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) sheds light on a genetic function that gives breast cancer cells the ability to survive and spread to the bone years after treatment has been administered.

Bone density unnecessary in women taking osteoporosis drugs
Monitoring bone mineral density in postmenopausal women taking osteoporosis drugs (bisphosphonates) is unnecessary and potentially misleading, revealed by researchers through a new study published on bmj.com.

Bariatric surgery increases fracture risk
Persons who undergo bariatric surgery may have a greater chance of experiencing broken bones, especially in their hands and feet, revealed by researchers at Mayo Clinic.

Green tea shows promise in leukemia
Mayo Clinic researchers are reporting positive results in early leukemia clinical trials using the chemical epigallocatechin gallate (EGCG), an active ingredient in green tea.

Bone marrow cell therapy for ischemic heart disease patients
The injection of bone marrow cells into the heart of patients with chronic myocardial ischemia (reduced blood flow to some areas of the heart) was associated with modest improvements in blood flow and function of the left ventricle, according to a study in the May 20 issue of JAMA.

Meditation may increase gray matter of brain
Push-ups, crunches, gyms, personal trainers - people have many strategies for building bigger muscles and stronger bones. But what can one do to build a bigger brain?

Humans driving increased dengue risk in Australia
Drought-proofing Australia's urban regions by installing large domestic water tanks may enable the dengue mosquito Aedes aegypti to regain its foothold across the country and expand its range of possible infections, according to a new study published May 5 in the open-access journal PLoS Neglected Tropical Diseases.

Sick patients tend to have low Vitamin D
A group of endocrinologists in Sydney have observed that very sick patients tend to have very low levels of Vitamin D. The sicker they are, the lower the levels.

Men should get PSA testing at age 40
The American Urological Association (AUA) issued new clinical guidance – which directly contrasts recent recommendations issued by other major groups – about prostate cancer screening, asserting that the prostate-specific antigen (PSA) test should be offered to well-informed, men aged 40 years or older who have a life expectancy of at least 10 years.

Osteoporosis drug boost bone's healing process
Osteoporosis drug teriparatide or Forteo can boost bodies' bone stem cell production to the point that adults' bones appear to have the ability to heal at a rate typically seen when they were young kids, revealed by researchers.

Leukemia treatment developed in Australia
Two Australian research groups are undertaking pioneering studies into the causes of leukaemia, potentially leading to patients receiving new drug treatments as early as next year.

ViroPharma's Maribavir failed in bone marrow transplant patients
ViroPharma Incorporated (Nasdaq: VPHM) announced that its Phase 3 trial evaluating maribavir used as prophylaxis in allogeneic stem cell, or bone marrow, transplant (SCT) patients did not achieve its primary endpoint.

Osteoporotic fracture risky in older adults
Women and men age 60 years or older who have a low-trauma osteoporotic fracture have an increased risk of death for the following 5 to 10 years, compared to the general population, and those who experience another fracture increase their risk of death further for an additional 5 years, according to a study in the February 4 issue of JAMA.

Stem cells to repair the body
Scientists have tricked bone marrow into releasing extra adult stem cells into the bloodstream, a technique that they hope could one day be used to repair heart damage or mend a broken bone, in a new study published today in the journal Cell Stem Cell.

Jaw necrosis risk from oral bisphosphonate, Fosomax
A new research study revealed that there an increased risk jaw necrosis from oral bisphosphonates like Fossamax type drugs used for osteoporosis.

A man defeated HIV virus through bone marrow transplant
An HIV-positive person, who underwent a bone marrow transplant to treat leukemia, has had undetectable HIV viral loads for almost two years. HIV-positive man was ill from leukemia and had underwent treatment by the team led by Prof. Eckhard Thiel, director of the Medical Clinic with a focus on hematology and oncology.

Bone marrow transplant can cure sickle cell disease
A unique approach to bone marrow transplantation pioneered in part by a Children's Hospital of Pittsburgh of UPMC physician has proven to be the only safe and effective cure for sickle cell disease, according to a new study.

Chemotherapy target found for leukemia
Cancer researchers at the Stanford University School of Medicine have discovered a promising new chemotherapy target for a deadly form of leukemia. Their discovery hinges on a novel "double agent" role for a molecular signal that regulates cell growth.

Merck's Odanacatib increases bone mineral density
2 year data from a Phase IIB study of odanacatib (formerly MK-0822), an investigational, selective cathepsin-K inhibitor in development for the treatment of osteoporosis by Merck & Co., Inc., demonstrated dose-dependent increases in bone mineral density (BMD) at the total hip, lumbar spine and femoral neck fracture sites and decreased indices of bone resorption compared to placebo in postmenopausal women with low BMD.

Nplate bone marrow stimulator approved to treat low platelet counts
The U.S. Food and Drug Administration approved Nplate (romiplostim), the first product that directly stimulates the bone marrow to produce needed platelets in patients with a rare blood disorder that can lead to serious bleeding.

Red wine may ward off effects of age on heart, bones, eyes and muscles
Large doses of a red wine ingredient can ward off many of the vagaries of aging in mice who begin taking it at midlife, according to a new report published online on July 3rd in Cell Metabolism, a Cell Press publication. Those health improvements of the chemical known as resveratrol-including cardiovascular benefits, greater motor coordination, reduced cataracts and better bone density-come without necessarily extending the animals' lifespan.

Breast cancer spread stopped by bone drug
Researchers at Washington University School of Medicine in St. Louis found that women treated for stage II/III breast cancer who also received a bone strengthening drug zoledronic acid were less likely to have breast tumor cells growing in their bones after three months.

Stem cell therapy trials to mend shattered bones
Scientists are developing a revolutionary way to mend damaged bones and cartilage using a patient's own stem cells.

Sickle cell disease pain occurs daily
Sickle cell disease pain can occur daily, and is far more prevalent and severe than previous large studies have indicated. Patients are at home mostly struggling with their pain rather than coming into the hospital or emergency department.

Calcium supplements may increase heart attacks in postmenopausal women
Calcium is an important component of bone, and a sufficient intake of calcium is needed for bone homoeostasis. Calcium supplements can reduce the risk of fractures in elderly women, but high calcium intakes or calcium supplements may increase the risk of heart attack in healthy postmenopausal women.

Osteoporosis drugs increase bone necrosis risk
A popular class of osteoporosis drugs, bisphosphonates nearly triples the risk of developing bone necrosis, a condition that can lead to disfigurement and incapacitating pain, revealed by researchers in a study. The research conducted by reasearchers at the University of British Columbia and Vancouver Coastal Health Research Institute, Canada.

Vitamin D deficiency may increase heart disease risk
The same vitamin D deficiency that can result in weak bones now has been associated with an increased risk of cardiovascular disease, Framingham Heart Study researchers report in Circulation: Journal of the American Heart Association.

Oral osteoporosis medicines safe during dental work
Some doctors and dentists had advised patients who take oral osteoporosis medications such as Fosamax and Boniva to postpone dental work, fearing that tooth extractions and other procedures would exacerbate jaw problems purportedly linked to the medication. But the new findings refute the link and suggest the benefits of dentistry likely outweigh the risks for many of these patients.

RNA may stop breast cancer spread
Now, researchers can develop more effective drugs to prevent or treat cancer metastasis, as they have identified a specific group of microRNA molecules that are responsible for controlling genes that cause breast cancer metastasis.

Don't postpone knee-replacement surgery
Research at the University of Delaware indicates that women wait longer to pursue knee-replacement surgery than men do.

Women with osteoporosis have increased long-term risk for new fracture
Over a 15 year period, women with low bone mineral density and a previous vertebral fracture had an increased risk of a new vertebral fracture compared to women with normal bone mineral density and no previous fracture, according to a study in the December 19 issue of JAMA.

Test for targeted therapy in acute myeloid leukemia
An Oregon Health & Science University Cancer Institute researcher has discovered that a particular hormone is responsible for driving a cancer enzyme to cause an often deadly red blood cell cancer.

Predicting hip fracture risk in postmenopausal women
To help doctors predict the five-year risk of hip fractures in their postmenopausal patients, a team of UC Davis researchers has developed a method that assesses nearly a dozen factors, including age, ethnicity and level of physical activity.

Obesity may be bad for bone health
Obesity may be bad for bone health, revealed by researchers at the University of Georgia. Being overweight is a known risk factor for heart disease, diabetes and a host of other health conditions. Now, obesity and over-weight may also be bad for bone health.

59 Bone articles listed above.

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