Breast Cancer
Breast cancer is the abnormal growth and uncontrolled division of cells in the breast. Cancer cells invade and destroy surrounding normal tissue, and can spread throughout the body via blood or lymph fluid (clear fluid bathing body cells) to start a new cancer in another part of the body.
Breast Cancer - most related articles:
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Breast cancer drug Tykerb to be subsidised - 5.4
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Breastfeeding mothers reduce breast cancer risk - 5
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Breast cancer recurrence high in women with dense breasts - 4.9
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Exercise reduces breast cancer risk - 4.9
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7% breast cancer patients have breast reconstruction surgery - 4.8
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Breast stem cell fate is regulated by notch - 4.8
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Body fat distribution linked to ER negative breast cancer - 4.7
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Coffee may reduce breast cancer risk - 4.7
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Cleaning products may cause breast cancer - 4.6
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BRCA mutation increases breast cancer risk in opposite breast - 4.6
Breast Cancer articles
Breast cancer funding restored by Komen Foundation to Planned ParenthoodThe Susan G. Komen for the Cure Foundation reversed its decision and continues to fund breast cancer screenings at Planned Parenthood health centers. The outpouring of support online for Planned Parenthood and women in need of breast cancer screenings has been nothing short of astonishing, and because of it, the Planned Parenthood Breast Health Fund has received more than $3 million from thousands of people across the country in only three days.
Susan G. Komen stops funding breast cancer programs at Planned ParenthoodPlanned Parenthood Federation of America expressed deep disappointment in response to the Susan G. Komen for the Cure Foundation's decision to stop funding breast cancer prevention, screenings and education at Planned Parenthood health centers.
Additional breast surgery common after partial mastectomyNearly one in four women who undergo a partial mastectomy for treatment of breast cancer have another surgery to remove additional tissue (reexcision), and there is substantial surgeon and institutional variation in the rate of reexcisions that cannot be explained by patients' clinical characteristics.
Parabens in underarm products may lead to breast cancer in womenNew research into the potential link between parabens and breast cancer has found traces of the chemicals in breast tissue samples from all of the women in the study. Parabens are commonly used as preservatives in cosmetics, food products and pharmaceuticals.
Red wine drinking may reduce breast cancer risk in womenA glass of red wine with dinner may reduce breast cancer risk in women.
Drinking red wine in moderation may reduce one of the risk factors for breast cancer, providing a natural weapon to combat a major cause of death among U.S. women, new research from Cedars-Sinai Medical Center shows.
Cancer screening in older adults appears common, USA high percentage of adults age 75 years and older continue to report receiving cancer screenings, despite U.S. Preventive Services Task Force guidelines recommending against routine screening for breast, cervical, colorectal and prostate cancer for patients age 75 years and older.
Breast cancer vaccine reduces tumours in miceResearchers have developed a vaccine that dramatically reduces tumors in a mouse model that mimics 90 percent of human breast and pancreatic cancer cases-including those that are resistant to common treatments.
Breast cancer survivors may experience mental abilities problemsBreast cancer survivors may experience problems with certain mental abilities several years after breast cancer treatment, regardless of whether they were treated with breast cancer chemotherapy plus radiation or radiation for breast cancer only.
HER growth proteins do not predict outcome of herceptin treatment breast cancer patientsPrecisely quantifying the amount of three different HER growth proteins, along with several other proteins believed linked to breast cancer, did not predict a patient's outcome after treatment for HER2 Positive Breast Cancer with Herceptin, say Mayo Clinic researchers.
Avastin bevacizumab approval revoked to treat breast cancer in USUS health agency FDA Commissioner Margaret A. Hamburg, M.D. has revoked the approval of the breast cancer indication for Avastin (bevacizumab) after concluding that the drug has not been shown to be safe and effective for that use.
Alcohol increases breast cancer risk in womenWomen who consume alcohol show an increase in their risk of developing breast cancer. This relation is stronger for women who drink in binges, are also taking post-menopausal hormonal therapy, and/or have low intakes of dietary folate.
Breast cancer risk increases with high hormone levelsEight different sex and growth hormones may rise the risk of breast cancer, each elevated hormone level increase risk by 16% in post-menopausal women.
7% breast cancer patients have breast reconstruction surgeryBreast reconstruction surgery has a very positive effort on women with breast cancer as they go through their breast cancer journey. Only 7% of female breast cancer patients opt for breast reconstruction surgery.
Novartis drug Afinitor everolimus helps advanced breast cancer womenA pivotal Phase III study shows Afinitor (everolimus) tablets plus exemestane, a hormonal therapy, more than doubled the time women lived without tumor growth (progression-free survival; PFS) and significantly reduced the risk of cancer progression by 57% versus exemestane alone in patients with advanced breast cancer.
$3.5 million Komen award to study rare and aggressive type of breast cancerThe Translational Genomics Research Institute (TGen) is part of a team of medical investigators receiving a $3.5 million grant from Susan G. Komen for the Cure to study triple-negative breast cancer, a highly aggressive form of this cancer that disproportionately affects African-Americans.
Stress linked to breast cancer aggressivenessPsychosocial stress could play a role in the etiology of breast cancer aggressiveness, particularly among minority populations, according to study results presented at the Fourth AACR Conference on The Science of Cancer Health Disparities, held.
Breast cancer and cervical cancer rising in developing countriesThe number of cases and deaths from breast and cervical cancer are rising in most countries, especially in the developing world where more women are dying at younger ages, according to a new global analysis by the Institute for Health Metrics and Evaluation (IHME) at the University of Washington.
Therapy reduces early menopause for women with breast cancerTemporarily suppressing ovarian function with use of the hormone analogue triptorelin reduced the occurrence of early menopause induced by chemotherapy among women with breast cancer, according to a study in the July_20 issue of JAMA.
FDA panel votes to revoke approval for Avastin for advanced breast cancerThe Oncologic Drugs Advisory Committee, FDA, USA disapproved the Avastin which cited a lack of survival benefit. Now as two more trials have been analyzed -- neither showing a survival benefit -- the FDA stated that in the balance, the benefit did not outweigh the harm.
Many advanced breast cancer patients do not receive recommended treatmentForty-five percent of women with advanced breast cancer in the U.S. did not receive postmastectomy radiation therapy (PMRT) despite the publication of evidence-based guidelines outlining PMRT as a potentially lifesaving treatment, according to new research from The University of Texas MD Anderson Cancer Center. The study, published in the July issue of Cancer, found that PMRT use rates for women with advanced breast cancer have remained static since 1999.
Shanghai Breast Health Resource Center ChinaThe prevention, early detection and multidisciplinary treatment of breast cancer are important strategies for promoting health and extending a healthy life span. The Shanghai Breast Health Resource Center is an important step in effectively addressing breast cancer, especially to improving breast cancer screening and early detection, which are considered to be the most effective and affordable ways for a rapid reduction of breast cancer disease burden in developing countries like China.
Inform Dual ISH to determine HER2 gene in breast cancer patientsBreast cancer is the second leading cause of cancer-related death among women. About 20 percent of women diagnosed with breast cancer are HER2-positive. The Inform Dual ISH test allows lab personnel to count the number of copies of HER2 genes on chromosome 17 in a small sample of the breast tumor. Copies of the HER2 gene appear black and copies of chromosome 17 appear red. Patients with more than the normal number of copies of the HER2 gene are considered candidates for Herceptin therapy.
Radiation improves survival in breast cancer surgery patientsAdditional radiation treatment improves disease free survival lessening the chance of cancer recurring in women with early breast cancer who have had breast conserving surgery (lumpectomy), interim results of a new study found. The results will be presented Monday, June_6 at the annual meeting of the American Society of Clinical Oncology.
Pfizer drug reduces breast cancer in high risk womenThe drug exemestane significantly reduces the risk of breast cancer in high-risk, postmenopausal women is the result of an international, randomized double-blind phase III clinical trial in which University at Buffalo researchers and hundreds of Western New York women played a critical role, revealed at the American Society of Clinical Oncology annual meeting.
How breast cancer cells adapt to environmental stressAn international research team led by Dr. Tak Mak, Director, The Campbell Family Institute for Breast Cancer Research at Princess Margaret Hospital (PMH), has discovered a new aspect of "metabolic transformation", the process whereby tumour cells adapt and survive under conditions that would kill normal cells.
Coffee may reduce breast cancer riskRecently published research shows that coffee drinkers enjoy not only the taste of their coffee but also a reduced risk of cancer with their cuppa.
Breast cancers found between mammograms more likely to be aggressiveBreast cancers that are first detectable in the interval between screening mammograms are more likely to be aggressive, fast-growing tumors according to a study published online May 3rd in the Journal of the National Cancer Institute.
A better imaging agent for heart disease and breast cancerScientists are reporting development of a process for producing large quantities of a much-needed new imaging agent for computed tomography (CT) scans in heart disease, breast cancer and other diseases, and the first evidence that the material is safe for clinical use.
New class of cancer drugs could work in colon cancers with genetic mutationA class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.
Breast cancer survivors at higher risk for fracturesThe combined effects of chemotherapy and endocrine therapy may increase the risk of bone fractures in breast cancer survivors, revealed by researchers in a study.
Hormone therapy at menopause may lead to breast cancerHormone therapy around menopause is linked to breast cancer risk, revealed by researchers in a study published in The Journal of the National Cancer Institute.
Breast implants linked to ALCL a rare cancerSaline and silicone gel-filled breast implants are linked to anaplastic large cell lymphoma (ALCL), a very rare type of cancer, announced by US Health Agency FDA.
Body fat distribution linked to ER negative breast cancerBody fat distribution does not play an important role in the incidence of every subtype of premenopausal breast cancer, but is associated with an increased risk for estrogen receptor (ER)–negative breast cancer.
New risk factor for developing breast cancerAn Australian research team from the Peter MacCallum Cancer Centre, the University of Melbourne and the University of Queensland has identified a new risk factor for developing breast cancer. This has been published online in the journal Cancer Prevention Research.
Genetic variants may affect risk of breast cancerAn international study led by researchers at Memorial Sloan-Kettering Cancer Center has identified genetic variants in women with BRCA2 mutations that may increase or decrease their risk of developing breast cancer.
Higher breast density increases breast cancer riskResearchers at Kaiser Permanente have found that patients with a very early form of breast cancer (ductal carcinoma in situ or DCIS) who have higher mammographic density may be at increased risk for subsequent breast cancer, especially in the breast opposite to the one with the initial cancer.
Mammogram alerts may save lives from breast cancerWomen confused about when to have a mammogram have a new interactive source of information - MammographySavesLives.org - launching this week along with a series of public service announcements on television and radio stations across US.
Preventive surgeries better in breast or ovarian cancer patientsA long-term study of women with a genetic predisposition for breast or ovarian cancer showed that those who elected major preventive surgeries had a significantly reduced risk of those cancers.
Preventive cancer surgeries save women's livesA new study underscores the importance for women with a family history of breast or ovarian cancer to get genetic counseling and testing for the BRCA1 and BRCA2 genes that make them more likely to develop lethal breast or ovarian cancer, says a Northwestern Medicine oncologist.
Cancer risk found for long-term hormone therapyUsing postmenopausal hormone therapy for more than 15 years increases a woman's risk of developing breast cancer, particularly among leaner women according to research at the Keck School of Medicine of the University of Southern California (USC).
Cleaning products may cause breast cancerWomen who report greater use of cleaning products may be at higher breast cancer risk than those who say they use them sparingly, revealed by researchers in a new study.
Fish oil may reduce breast cancer riskA recent report in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, adds to the growing evidence that fish oil supplements may play a role in preventing chronic disease like breast cancer.
Cancer deaths continue to drop in USThe continued drop in overall cancer mortality rates over the last 20 years has averted more than three-quarters of a million (767,000) cancer deaths according to a new report from the American Cancer Society.
49% breast cancer patients adhere to hormonal therapy regimenA new study of nearly 8,800 women with early-stage breast cancer found that fewer than half – approximately 49 percent – completed their full regimen of hormone therapy according to the prescribed schedule.
Single radiation to treat breast cancerThe researchers from an international TARGIT research group found a new method of radiotherapy for breast cancer in which the treatment can be reduced to a single radiation exposure.
Screening mammography for breast cancer improvedResearchers analyzing 2.5 million screening mammograms performed on nearly one million women found discrimination of cancerous from non-cancerous lesions improved over a nine-year period. Results of the study are published in the online edition of the journal Radiology.
Exercise may keep cancer patients healthierBreast and prostate cancer patients who regularly exercise during and after cancer treatment report having a better quality of life and being less fatigued, according to researchers at Henry Ford Hospital in Detroit.
Estrogen lowering drugs minimize surgery in breast cancer patientsA US study has confirmed the benefit of giving estrogen-lowering drugs before surgery to breast cancer patients. The treatment increased the likelihood that women could undergo breast-conservation surgery, also called lumpectomy, instead of mastectomy.
Gene test identifies subtypes of breast cancerA simple genetic test that uses just three genes is among the most effective means of classifying breast cancer into sub-types, US researchers report at the IMPAKT Breast Cancer Conference in Brussels, Belgium.
Sulforaphane in broccoli may limit breast cancer cellsA compound derived from broccoli could help prevent or treat breast cancer by targeting cancer stem cells -- the small number of cells that fuel a tumor's growth -- according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.
Adolescent drinking adds to risk of breast disease breast cancerGirls and young women who drink alcohol increase their risk of benign (noncancerous) breast disease, says a study by researchers at Washington University School of Medicine in St. Louis and Harvard University.
BRCA mutation increases breast cancer risk in opposite breastWomen with breast cancer before age 55 who carry an inherited mutation in the breast cancer susceptibility genes BRCA1 or BRCA2 are four times more likely to develop cancer in the breast opposite, or contralateral, to their initial tumor as compared to breast cancer patients without these genetic defects.
Isolated DNA Claims are Not Patentable, USA federal judge on Monday struck down patents on two genes -- BRCA1 and BRCA2 -- linked to breast and ovarian cancer. Shares of Myriad Genetics (MYGN.O) fell as much as 7 percent, a day after the ruling.
Genomic sequencing of difficult breast cancersLife Technologies Corporation (NASDAQ: LIFE) announced that it is collaborating with the Translational Genomics Research Institute (TGen) and US Oncology to sequence the genomes of 14 patients afflicted with triple negative breast cancer whose tumors have progressed despite multiple other therapies.
Radiotherapy delay increases breast cancer recurrence riskOlder women who have had breast cancer surgery have a greater risk of the cancer returning if they delay their post-surgical radiation treatment, report Dana-Farber Cancer Institute scientists.
Genetic link between breast density and breast cancerA University of Melbourne study has revealed that certain breast cancer genetic variants increase mammographic density, confirming the link between mammographic breast density and breast cancer.
Few US women take tamoxifen to prevent breast cancerResearchers with the National Cancer Institute (NCI) have found that the prevalence of tamoxifen use for the prevention of breast cancer among women without a personal history of breast cancer is very low.
Genes found linked to breast cancer drug resistanceResearchers at Dana-Farber Cancer Institute have discovered a gene activity signature that predicts a high risk of cancer recurrence in certain breast tumors that have been treated with commonly used chemotherapy drugs.
Pomegranates may prevent breast cancer growthEating fruit, such as pomegranates, that contain anti aromatase phytochemicals reduces the incidence of hormone-dependent breast cancer, according to results of a study published in the January issue of Cancer Prevention Research, a journal of the American Association for Cancer Research.
Breast cancer screening should begin at age 40Breast cancer screening should begin at age 40 and earlier in high-risk patients, suggested by the Society of Breast Imaging (SBI) and the American College of Radiology (ACR).
Tykerb with Herceptin increases advanced breast cancer survivalAn investigational combination of TYKERB (lapatinib) plus HERCEPTIN (trastuzumab) proved a median survival of 14 months in women with an aggressive form of breast cancer.
Herceptin with chemotherapy improves breast cancer survivalUsing Herceptin with chemotherapy clearly improves treatment of women with HER2+ breast cancer, and should be the new standard of care, says a Mayo Clinic researcher.
MRI detects breast cancer at earlier stageMagnetic resonance imaging (MRI) coupled with mammography detects almost all cancers at an early stage, thereby reducing the incidence of advanced stage breast cancer in high-risk women.
Caution about mammography use among women younger than 40 yearsBreast cancer screening guidelines generally recommend mammography begin at age 40. However, based on prior national research, an estimated 34 percent of non-Hispanic black women, 30 percent of non-Hispanic white women and 22 percent of Hispanic women aged 30 to 39 have reported having a mammogram.
Soy food lowers breast cancer recurrenceAlthough there is a concern regarding the safety of soy food consumption among breast cancer survivors, researchers have found that women in China who had breast cancer and a higher intake of soy food had an associated lower risk of death and breast cancer recurrence.
Isolation and stress contribute to breast cancer riskSocial isolation and related stress could contribute to human breast cancer susceptibility, research from a rat model designed at the University of Chicago to identify environmental mechanisms contributing to cancer risk shows.
Breast ultrasound can reduce breast biopsies in young womenTargeted breast ultrasound of suspicious areas of the breast, including lumps, is a safe, reliable and cost-effective alternative to invasive biopsies for women under age 40.
Pregnancy hormone may prevent breast cancerResearchers have found that hormones produced during pregnancy induce a protein that directly inhibits the growth of breast cancer. This protein, alpha-fetoprotein (AFP), may serve as a viable, well-tolerated agent for the treatment and prevention of breast cancer.
Mammogram policy unchanged for breast cancer screening, USHHS Secretary Kathleen Sebelius issued the following statement today on new breast cancer screening recommendations from the U.S. Preventive Services Task Force:
Less hormone therapy use in women reduced breast cancer rateThe decreased use of postmenopausal hormone therapy has played a key role in the declining rate of atypical ductal hyperplasia, a known risk factor for breast cancer, revealed by researchers.
Breast cancer drugs may prevent cervical cancer alsoResearchers eliminated cervical cancer in mice with two FDA-approved drugs currently used to treat breast cancer and osteoporosis. The study is published in the Proceedings of the National Academy of Sciences.
Breast cancer recurrence high in women with dense breastsWomen treated for breast cancer are at higher risk of cancer recurrence if they have dense breasts, revealed by researchers in a study published in the Cancer -- journal of the American Cancer Society.
African American women get delay in breast cancer related careAfrican-American women face obstacles to receive appropriate breast cancer–related care in US. There is a significant delay in follow-up times among African-American women after the finding of a suspicious breast abnormality.
Researchers decoded genetic evolution of a breast cancer tumourCanadian researchers have decoded all of the three billion letters in the DNA sequence of a metastatic lobular breast cancer tumor, a type of breast cancer which accounts for about 10 per cent of all breast cancers.
Exercise reduces breast cancer riskPost-menopausal women who engage in moderate to vigorous exercise and physical activity have a reduced risk of breast cancer, revealed by researchers. Breast cancer is recognized as the most common cancer affecting US women.
Social interaction or isolation affects breast cancerSocial environment can play an important role in the biology of disease, including breast cancer, and lead to significant differences in health outcome, revealed by researchers.
Environmental chemicals in breast milk may cause testicular cancer laterA comparison of breast milk samples from Denmark and Finland revealed a significant difference in environmental chemicals which have previously been implicated in testicular cancer or in adversely affecting development of the fetal testis in humans and animals.
Obesity, alcohol use and smoking increase second breast cancer riskObesity, alcohol use and smoking significantly increase the risk of second breast cancer among breast cancer survivors, revealed by researchers at the Fred Hutchinson Cancer Research Center.
Salinomycin potent against cancer stem cells in breast cancerA multi-institutional team of Boston-area researchers has discovered a chemical salinomycin that works in mice to kill the rare but aggressive cells within breast cancers that have the ability to seed new tumors.
Newly diagnosed breast cancer patients and MRINew research findings published in the August issue of the Journal of the American College of Surgeons challenge the routine use of magnetic resonance imaging (MRI) as a means to improve surgical outcomes in newly diagnosed breast cancer patients.
Breastfeeding reduces risk of breast cancerWomen with a family history of breast cancer were 59 percent less likely to develop breast cancer themselves if they breastfed their children, revealed by US researchers.
Women opt surgery to remove breasts, ovaries to reduce cancer riskMany women at high risk for breast or ovarian cancer are choosing to undergo surgery as a precautionary measure to decrease their cancer risk, revealed by US researchers.
Breast cells responsible for breast cancersBreast cells called luminal progenitor cells are likely to be responsible for breast cancers that develop in women carrying mutations in the gene BRCA1, revealed by researchers.
Math may predict Herceptin response in breast cancer patientsCancer researchers are turning to mathematical models to help answer important clinical questions, and a new paper in Cancer Research, a journal of the American Association for Cancer Research, illustrates how the technique may answer questions about Herceptin resistance.
Breast cancer drug Abraxane promising for malignant melanoma treatmentAn approved breast-cancer drug nab-paclitaxel, trade named Abraxane, has been found promising in clinical trial for the treatment of metastatic malignant melanoma, revealed by researchers.
New consensus on using APBI to treat breast cancerA new consensus statement outlining patient selection criteria and best practices for the use of accelerated partial breast irradiation (APBI) outside the context of a clinical trial has been published in the July 15 issue of the International Journal of Radiation Oncology Biology Physics.
Breast cancer's ability to relapse linked to genesNew research led by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) sheds light on a genetic function that gives breast cancer cells the ability to survive and spread to the bone years after treatment has been administered.
Routine MRI scan to evaluate breast cancer is challengedWomen with newly diagnosed breast cancer who receive a breast MRI are more likely to receive a mastectomy after their diagnosis and may face delays in starting treatment, revealed by researchers.
Cancer - a concern in schizophrenia patientsSchizophrenia patients are four times as likely to die from all causes and are 50 percent more likely to die from cancer compared to people in the general population, revealed by researchers.
Antioxidant supplements may interfere breast cancer treatmentA new study finds that many women with breast cancer take antioxidant supplements while undergoing cancer treatment, even though the consequences of doing so are unknown.
Wet ear wax and unpleasant body odors signal breast cancer riskIf having malodorous armpits (called osmidrosis) and goopy earwax isn't bad enough, a discovery by Japanese scientists may add a more serious problem for women facing these cosmetic calamities.
Breast cancer gene responds to blood pressure drug in labResearchers have identified a gene that is overexpressed in up to 20 percent of breast cancers and that could be blocked in the lab by a currently available blood pressure drug, according to a new study from the University of Michigan Comprehensive Cancer Center.
Neratinib shows promise in trastuzumab resistant breast cancerFox Chase Cancer Center researchers report that a combination of trastuzumab and neratinib (HKI-272) a novel small molecule inhibitor of the HER2 receptor (ErbB2) appears active in women with HER2-positive metastatic breast cancer who have progressed on previous trastuzumab based therapies.
Breast cancer markers discovered in breast cancer survivorsA study led by researchers at Fred Hutchinson Cancer Research Center has identified two proteins in the blood that could become important prognostic markers for long-term survival in breast cancer patients.
African American women often refuse breast cancer treatmentA new study finds that nearly one in four African American women with late stage breast cancer refused chemotherapy and radiation therapy, potentially life saving therapies.
HRT-breast cancer risk stays same regardless of family historyThe risk of developing breast cancer due to taking hormone replacement therapy appears to be the same for women with a family history of the disease and without a family history, a University of Rochester Medical Center study concluded.
Low income breast cancer patients skipping hormonal therapyMany low-income women are failing to take the hormonal therapy prescribed as part of their breast cancer treatment, possibly lowering their survival rates, according to a study led by a researcher in the Duke Comprehensive Cancer Center.
Triple drug combination promising to treat breast cancerCombining two chemotherapy drugs with trastuzumab (Herceptin) to treat women who have metastatic HER2+ breast cancer may offer physicians another choice in their treatment options.
AMP joins ACLU to challenge BRCA gene patentsThe Association for Molecular Pathology (AMP) announced that it is working with the American Civil Liberties Union (ACLU) and the Public Patent Foundation to bring a lawsuit charging that patents on two human genes associated with breast and ovarian cancer are unconstitutional and should be invalidated.
Chemotherapy improves survival among older breast cancer patientsThe average age of a woman diagnosed with breast cancer is 63, so it is critical to have effective proven, therapies for an older patient population.
100 Breast Cancer articles listed above.