Chronic Disease
Hepatitis C declines health with liver diseaseAn NIH funded multi-center clinical trial found no benefit from "maintenance therapy," low-dose peginterferon used for hepatitis C patients who have not responded to an initial round of treatment.
109 medicines, vaccines in development for HIV AIDSAmerica's pharmaceutical research companies are testing 109 medicines and vaccines to treat or prevent HIV/AIDS and related conditions, according to a report released by the Pharmaceutical Research and Manufacturers of America (PhRMA).
A universal mechanism of aging is identifiedResearchers have discovered that DNA damage decreases a cell's ability to regulate which genes are turned on and off in particular settings. This mechanism, which applies both to fungus and to us, might represent a universal culprit for aging.
14 drugs identified for off label usePhysicians and policy-makers know that drugs are frequently prescribed to treat certain diseases despite a lack of FDA approval - a practice known as off-label prescribing. Yet they say the problem is so big they don't know how to begin tackling it.
Weight loss maintenance through telephone is effectiveFace-to-face and telephone follow-up sessions appear to be more effective in the maintenance of weight loss for women from rural communities compared with weight loss education alone, according to a report in the November 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Asthma risk more in children born in autumnChildren who are born four months before the peak of cold and flu season have a greater risk of developing childhood asthma than children born at any other time of year, according to new research from Vanderbilt University Medical Center.
COPD hospitalizations on the rise in USA joint report released by the American Lung Association of Minnesota and the Minnesota COPD Coalition shows that chronic obstructive pulmonary disease (COPD) is sending more Minnesotans to the hospital, and may be contributing to rising health care costs across in the state.
Marijuana reduces memory impairmentThe more research they do, the more evidence Ohio State University scientists find that specific elements of marijuana can be good for the aging brain by reducing inflammation there and possibly even stimulating the formation of new brain cells.
Factors identified causing barriers to asthma careBarriers to managing asthma include access to appropriate care, patient adherence, distrust of the medical profession, delayed asthma diagnosis, culture, lifestyle choices and genetic discrepancies according to experts at the annual meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in Seattle.
Rheumatoid arthritis rising among women in USAfter four decades on the decline, rheumatoid arthritis is on the upswing among women in the United States. That's the finding presented by Mayo Clinic investigators at the annual meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals in San Francisco.
Chinese exercise Tai chi relieves knee painTai chi is effective in the treatment of pain and physical impairment in people with severe knee osteoarthritis, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in San Francisco, Calif.
Purple, high anthocyanin tomatoes offer protection against certain cancersScientists have expressed genes from snapdragon in tomatoes to grow purple tomatoes high in health-protecting anthocyanins.
New drug alemtuzumab for multiple sclerosis patientsA drug which was developed in Cambridge and initially designed to treat a form of leukaemia has also proven effective against combating the debilitating neurological disease multiple sclerosis (MS).
Updated labeling for psoriasis drug Raptiva approvedThe U.S. Food and Drug Administration announced labeling changes, including a Boxed Warning, to highlight the risks of life-threatening infections, including progressive multifocal leukoencephalopathy (PML), with the use of Raptiva (efalizumab).
Indoor pollution in homes in China causing respiratory diseasesIf current levels of smoking and biomass and coal fuel use in homes continues, between 2003 and 2033 there will be an estimated 65 million deaths from chronic obstructive pulmonary disease (COPD) and 18 million deaths from lung cancer in China, accounting for 19% and 5% of all deaths in that country during this period.
Brain pathway responsible for obesity discoveredUniversity of Wisconsin-Madison researchers, for the first time, have found a messaging system in the brain that directly affects food intake and body weight.
Decade of change in general practice in AustraliaIt's not only the patients in GP surgeries who are getting older, according to two new reports released today by the Australian Institute of Health and Welfare and the Australian General Practice Statistics and Classification Centre, an AIHW collaborating unit located at the University of Sydney.
Childhood wheezing with rhinovirus can increase asthma riskInfants who experience viral respiratory illnesses with wheezing are known to be at increased risk for developing asthma later during childhood. It is not known, however, whether every type of respiratory virus that produces wheezing presents similar risk.
Paracetamol use raises childhood asthma riskA strong association between paracetamol use in infancy and increased risk of asthma by age 6-7 years, suggested by researchers in a new study published in the Lancet.
Nplate bone marrow stimulator approved to treat low platelet countsThe U.S. Food and Drug Administration approved Nplate (romiplostim), the first product that directly stimulates the bone marrow to produce needed platelets in patients with a rare blood disorder that can lead to serious bleeding.
Boys grow out of childhood asthmaBoys may be more apt than girls to have childhood asthma, but, when compared to girls, they are also more likely to grow out of it in adolescence and have a decreased incidence of asthma in the post-pubertal years. This indicates that there may be a buried mechanism in asthma development, according to a prospective study that analyzed airway responsiveness (AR) in more than 1,000 children with mild to moderate asthma over a period of about nine years.
Lower cholesterol early in lifeWith heart disease maintaining top billing as the leading cause of death in the United States, a team of University of California, San Diego School of Medicine physician-researchers is proposing that aggressive intervention to lower cholesterol levels as early as childhood is the best approach available today to reducing the incidence of coronary heart disease.
California Governor Schwarzenegger signed Trans Fat BillCalifornia Governor signed AB 97 by Asm. Mendoza, which will phase out the use of trans fats in all CA restaurants beginning in 2010. Scientific evidence demonstrates a strong association between the consumption of artificial trans fat and the development of coronary heart disease and stroke.
Nut products during pregnancy increases asthma risk in childrenExpectant mothers who eat nuts or nut products like peanut butter daily during pregnancy increase their children's risk of developing asthma by more than 50 percent over women who rarely or never consume nut products during pregnancy, according to new research from the Netherlands.
Broccoli rich diet prevents prostate cancerFor the first time, a UK research group at the Institute of Food Research led by Professor Richard Mithen has provided an explanation of how eating broccoli might reduce cancer risk based upon studies in men, as opposed to trying to extrapolate from animal models.
Rheumatoid arthritis risk higher in people with high birth weightPeople who have a birth weight over 10 pounds are twice as likely to develop rheumatoid arthritis when they are adults compared to individuals born with an average birth weight, according to a study published by researchers from Hospital for Special Surgery online in advance of print in the Annals of the Rheumatic Diseases.
Invest in a future without dementia, Alzheimer's diseaseAlzheimer's Australia released a report 'Australian Dementia Research' that recommends annual funding for dementia research be increased three-fold to $36 million in response to the growing economic and social impact of the dementia epidemic.
Travelers' diarrhea vaccine skin patch for travelersResearchers at The University of Texas School of Public Health have found that patients given a travelers' diarrhea vaccine were significantly less likely to suffer from clinically significant diarrhea than those who received placebo, according to a study published in this week's edition of The Lancet.
First-born babies' have higher asthma and allergy ratesFirst-born children are at higher risk of developing asthma and allergy because of different conditions they experience in the uterus, revealed by researchers.
Purple passion fruit peel reduces asthma symptomsPassion fruit peel can significantly improve the symptoms of asthma. Patients given an extract from the Purple passion fruit's peel had reduced wheezing, coughing and shortness of breath, due to anti-oxidant, anti-allergic and anti-inflammatory properties of Purple passion fruit.
Asthma in obese more severeObesity can worsen the impact of asthma and may also increase its severity, according to new University of Otago research.
Gene variant CHI3L1 increases risk of asthmaA tiny variation in a gene known as CHI3L1 increases susceptibility to asthma, bronchial hyperresponsiveness and decline in lung function, researchers report early online in the New England Journal of Medicine.
Aspirin reduces asthma risk in womenAspirin in small quantity on alternate days can cut the risk of developing asthma among women, suggests a large study, published ahead of print in Thorax from UK.
Sexual performance holds key to men's healthThe Australian male pride in sexual performance may help the fight against increasing obesity. This will be one of the messages from internationally regarded expert on obesity, men's health and ageing Professor Gary Wittert at the University of Adelaide's free Public Seminar Series.
Diesel exhaust inhalation stresses your brainIf the smell of diesel exhaust isn't enough to make you avoid getting a lungful, new research now shows that even a short exposure to the fumes can affect your brain. The study reveals that an hour of sniffing exhaust induces a stress response in the brain's activity.
Skin prick tests identify asthma risk for toddlers with eczemaToddlers with eczema who have a positive skin prick test for allergy have almost triple the risk of developing asthma than those with a negative test, says an Australian study.
March as Kidney Disease Awareness Month in USThe American Association of Kidney Patients (AAKP) is pleased to recognize March as National Kidney Disease Awareness Month. Recent research funded by the National Institute of Health put the number of chronic kidney disease (CKD) patients in the United States at 26 million. AAKP recognizes National Kidney Disease Awareness Month with several planned educational programs and events.
Schistosomiasis more debilitating than estimatedThe health effects of one strain of schistosomiasis, a parasitic disease common in developing countries, are seven to 46 times greater than previously estimated, according to new Brown University research.
Tobacco use, secondhand smoke exposure during pregnancy, may threaten healthRates of tobacco use during pregnancy, as well as exposure of pregnant women and their young children to secondhand smoke, are significant threats to health in several low and middle-income countries, reveals a study from National Institutes of Health (NIH).
Influenza vaccination for children 6 months through 18 years of ageA panel of immunization experts voted to expand the recommended ages for annual influenza vaccination of children to include all children from 6 months through 18 years of age. The previous recommendation was for vaccination of children from 6 months to 59 months of age.
Bowel cancer rising in Australia, reports AIHWA new Australian report released by the Australian Institute of Health and Welfare (AIHW) presents a mixed bag on favourable and unfavourable trends in chronic diseases over time. The report, Indicators for chronic disease and their determinants, 2008, focuses on the 12 chronic conditions that represent a large burden of disease in Australia.
Improved cognitive health among older AmericansHigher levels of health education improved cognitive health among older Americans. Rates of cognitive impairment among older Americans are on the decline, according to a new study supported by the National Institutes of Health (NIH) comparing the cognitive health of older people in 1993 and 2002.
Safer effective way to treat Crohn's diseaseA new study established the new alternative strategy, called "top-down" therapy, to treat the patients with Crohn's disease by employing early use of immune-suppressing drugs combined with an antibody without using steroids.
Managers less likely to suffer from cancersManagers and administrators are less likely to suffer from cancers, possibly because they are less exposed to risk factors or because they can more easily afford to retire when their health deteriorates.
HIV persists in gut despite long term HIV therapyHIV virus is not usually eradicated from infected individuals even after long term HIV therapy because of the persistence of HIV in hideouts known as viral reservoirs. One important reservoir is the gut, where HIV causes much of its damage due to the large number of HIV target cells that reside there.
Healthy lifestyle for long lifeA healthy lifestyle during the early elderly years-including weight management, exercising regularly and not smoking-may be associated with a greater probability of living to age 90 in men, as well as good health and physical function, according to a report in the February 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
New hope for hepatitis C sufferersUniversity of Adelaide virologists Dr Michael Beard and Dr Karla Helbig will work with colleagues from the University of NSW to develop new strategies to treat and prevent hepatitis C, which infects more than 170 million people around the world.
Genetic mutation increases risk of preterm birthGenetic mutations in the Toll-like receptor 4 (TLR4) gene appear to have significant association with inflammatory injury to the placenta and developing baby, researchers from the University of Pittsburgh's department of obstetrics, gynecology and reproductive sciences report at the 28th annual meeting of the Society for Maternal-Fetal Medicine. Scientific sessions continue through Saturday, Feb. 2, at the Dallas Hyatt Regency at Reunion.
27% lower mortality in top hospitals, finds HealthGradesPatients treated at top-rated hospitals in US are nearly one-third less likely to die, on average, than those admitted to all other hospitals, according to a study released by HealthGrades (Nasdaq: HGRD), the leading independent healthcare ratings organization.
Sugary soft drinks linked to gout in menConsumption of sugar sweetened soft drinks and fructose is strongly associated with an increased risk of gout in men. Gout is a joint disease which causes extreme pain and swelling. It is most common in men aged 40 and older. It is caused by excess uric acid in the blood (hyperuricaemia) which leads to uric acid crystals collecting around the joints.