Colon Cancer

Cancer of the colon is the disease characterized by the development of malignant cells in the lining or epithelium of the first and longest portion of the large intestine. Malignant cells have lost normal control mechanisms governing growth. These cells may invade surrounding local tissue, or they may spread throughout the body and invade other organ systems.

Colon Cancer - most related articles:

- Obesity in colon cancer patients increases mortality - 5.6
- Rectal cancer rates rising in young individuals in US - 5.1
- How diarrheal bacteria cause some colon cancers revealed - 4.8
- Surgery not necessary for most late stage colorectal cancers - 4.8
- Colon cancer's genetic link to obesity - 4.7
- Gene linked to Celebrex treatment for colon tumor prevention - 4.6
- New blood test promise diagnosis of colon cancer - 4.4
- Colonoscopy's limitation for right sided colon cancer - 4.4
- Evaluating risk factors of sporadic colorectal cancer - 4.2
- Colorectal cancer deaths are down in US - 4.2

Colon Cancer articles

Regorafenib improves survival of colorectal cancer patients
Regorafenib - an investigational drug - slowed the progression of tumors and lengthened the lives of patients with metastatic colorectal cancer. This is the first novel agent in eight years to show improvement in overall survival of colon cancer patients who have run out of treatment options.

New class of cancer drugs could work in colon cancers with genetic mutation
A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.

Activation of biomarker may improve survival among obese patients with colorectal cancer
Among obese patients, activation of the protein biomarker CTNNB1 was associated with better colorectal cancer-specific survival and overall survival, whereas post-diagnosis physical activity was associated with better colorectal cancer-specific survival among patients negative for CTNNB1.

New stool test to predict colon cancer
An investigational DNA methylation test could alter the screening landscape for colorectal cancer, according to data presented at the American Association for Cancer Research special conference on Colorectal Cancer: Biology to Therapy, held here Oct. 27-30, 2010.

Obesity in colon cancer patients increases mortality
Postmenopausal women diagnosed with colon cancer may be at increased risk of death if they fail to maintain a healthy body weight before cancer diagnosis, revealed by researchers.

Rectal cancer rates rising in young individuals in US
A new analysis has found that while colon cancer rates have remained steady over the past several decades among people under the age of 40, rectal cancer rates are increasing in this population across races and in both sexes.

Omega 3 curbs precancerous growths in those prone to bowel cancer
A purified form of an omega 3 cuts the number and size of precancerous bowel growths (polyps) in people whose genetic make-up predisposes them to bowel cancer, finds research published ahead of print in the journal Gut.

Young women with colon cancer lived longer than men
Younger women with metastatic colorectal cancer lived longer than younger men, revealed by researchers in a new US study. However, this survival advantage disappeared with age, suggesting a benefit from estrogen or other hormones.

New blood test promise diagnosis of colon cancer
Promising results from a new blood test that can aid in the early identification of patients with colon cancer will be presented at Europe's largest cancer congress, in Berlin today.

How diarrheal bacteria cause some colon cancers revealed
Johns Hopkins scientists say they have figured out how bacteria that cause diarrhea may also be the culprit in some colon cancers. The common Bacteroides fragilis (ETBF) dupe immune system cells into permitting runaway colon tissue inflammation, a precursor for malignant growth.

Cetuximab for colorectal cancer with KRAS gene
From a health-care system perspective, it may be more efficient to use the drug cetuximab only in colorectal cancer patients whose tumors have a wild-type KRAS gene, according to a study published online August 7 in the Journal of the National Cancer Institute.

CT colonography better for colorectal cancer screening
Computed tomographic (CT) colonography may offer patients at increased risk of colorectal cancer an alternative to colonoscopy that is less-invasive, is better-tolerated and has good diagnostic accuracy.

Evaluating risk factors of sporadic colorectal cancer
Colorectal cancer (CRC) is one of the most common cancers in China. Although the association between the epidemiological factors and sporadic colorectal cancer is not known and still remains uncertain.

Colorectal cancer rising in young adults 20-29 years in US
A new study finds that in sharp contrast to the overall declining rates of colorectal cancer in the United States, incidence rates among adults younger than age 50 years are increasing.

Advance in bowel cancer test research - gene expression biomarkers
Australian researchers have developed gene expression biomarkers which can accurately discriminate pre-cancerous and cancerous colorectal growths from non-cancerous controls.

Gene linked to Celebrex treatment for colon tumor prevention
A new study finds that individuals who have low expression of the "Celebrex gene," 15-PGDH, are actually resistant to Celebrex treatment when used to prevent colon cancer.

Hormone therapy reduces woman's risk of colorectal cancer by 40%
In a large study, a national team of researchers led by Mayo Clinic scientists observed that self-reported use of hormone therapy was associated with a significantly lower colorectal cancer risk. However, the mechanisms for the apparent protective association are still unclear.

Cancer is preventable through diet, physical activity and weight maintenance
A new global policy report estimates that approximately 45 percent of colon cancer cases and 38 percent of breast cancer cases in the US are preventable through diet, physical activity and weight maintenance.

Benefits from screening colonoscopy limited
Screening colonoscopy is associated with fewer deaths from colorectal cancer, and the association is primarily limited to deaths from cancer developing in the left side of the colon, revealed by researchers.

Colonoscopy's limitation for right sided colon cancer
A new study finds that colonoscopy is strongly associated with fewer deaths from colorectal cancer. However, the risk reduction appears to be entirely due to a reduction in deaths from left-sided cancers.

Colorectal cancer rate declines in US
The American Society for Gastrointestinal Endoscopy (ASGE) heralds the recent news of a decline in U.S. cancer deaths and incidence rates, with colorectal cancer among the top three cancers with significant declines.

Colonoscopy associated with reduced colorectal cancer incidence
Patients who undergo a complete negative colonoscopy have a reduced incidence of colorectal cancer, confirms a study published in Clinical Gastroenterology and Hepatology.

Colon cancer's genetic link to obesity
A new study reveals the first-ever genetic link between obesity and colon cancer risk, a finding that could lead to greater accuracy in testing for the disease, said a researcher at the University of Alabama at Birmingham (UAB).

CT colonography a viable colorectal cancer screening option
Death from colorectal cancer is highly preventable with effective screening and early detection. Many screening options are available, each with advantages and disadvantages, but half of eligible patients still do not participate in colorectal cancer screening.

A genetic trait identified for colorectal cancer risk
Scientists at Northwestern University's Feinberg School of Medicine and colleagues have discovered a genetic trait that is present in 10 to 20 percent of patients with colorectal cancer. The findings strongly suggest that the trait is a major contributor to colorectal cancer risk and likely the most common cause of colorectal cancer to date.

Colorectal cancer screening guidelines update
A new guideline on colorectal cancer screening released by an expert group representing a broad spectrum of health care organizations, including the American College of Gastroenterology (ACG), the American Society for Gastrointestinal Endoscopy (ASGE) and the American Cancer Society (ACS), offers recommendations for various alternatives for colorectal cancer detection and states a strong preference for screening tests that can prevent colorectal cancer.

Red meat consumption linked to colorectal cancer
For most Americans, meals tend to center around meat. To significantly decrease a person's risks of developing colorectal cancer, experts at The University of Texas M. D. Anderson Cancer Center suggest a new approach to meal planning that focuses more on fruit and vegetable dishes.

Bowel cancer rising in Australia, reports AIHW
A new Australian report released by the Australian Institute of Health and Welfare (AIHW) presents a mixed bag on favourable and unfavourable trends in chronic diseases over time. The report, Indicators for chronic disease and their determinants, 2008, focuses on the 12 chronic conditions that represent a large burden of disease in Australia.

Colorectal cancer deaths are down in US
New data revealing decreasing trends in cancer deaths in the United States overall, and in colorectal cancer deaths in particular, highlight the remarkable benefits of colorectal cancer screening tests, but the lifesaving potential of these tests is unrealized for many Americans, according to experts from the American College of Gastroenterology.

Excess bodyweight raises cancers risk
Increased body mass index (BMI) increases the risk of common and less common cancers, and the level of risk can vary between the sexes and different ethnic groups depending on the type of cancer.

Colonoscopy fears overcome when patients support patients
Patients who have had a colonoscopy can play a life-saving role by encouraging other patients to follow through with their own colorectal cancer screenings, according to new research from the University of Pennsylvania School of Medicine. These peer coaches can provide important information to combat myths and fears that serve as barriers to colonoscopy – issues patients say their doctors often fail to address.

Colon cancer screenings could pose harm to some
Even though current guidelines advocate colorectal cancer screenings for those with severe illnesses, they may bring little benefit and may actually pose harm, according to a recent study by Yale School of Medicine researchers published in the Archives of Internal Medicine.

Night shift work may cause cancer
A study by the World Health Organization has found that night shift work increases the risk of cancer in humans. The study found that after prolonged exposure to night shift work, women are at a higher risk to develop breast and colon cancer. Men who work the night shift are more likely to experience prostate cancer.

33 Colon Cancer articles listed above.

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What is Colon Cancer
Cancer of the colon is the disease characterized by the development of malignant cells in the lining or epithelium of the first and longest portion of the large intestine. Malignant cells have lost normal control mechanisms governing growth. These cells may invade surrounding local tissue, or they may spread throughout the body and invade other organ systems.

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