Disease

Hepatitis C declines health with liver disease
An NIH funded multi-center clinical trial found no benefit from "maintenance therapy," low-dose peginterferon used for hepatitis C patients who have not responded to an initial round of treatment.

International Society for Stem Cell Research releases new guidelines
The International Society for Stem Cell Research (ISSCR), the world's leading professional organization of stem cell researchers, released new guidelines for the responsible development of safe and effective stem cell therapies for patients.

109 medicines, vaccines in development for HIV AIDS
America's pharmaceutical research companies are testing 109 medicines and vaccines to treat or prevent HIV/AIDS and related conditions, according to a report released by the Pharmaceutical Research and Manufacturers of America (PhRMA).

A universal mechanism of aging is identified
Researchers have discovered that DNA damage decreases a cell's ability to regulate which genes are turned on and off in particular settings. This mechanism, which applies both to fungus and to us, might represent a universal culprit for aging.

Whooping cough booster for parents of newborns
A booster vaccination for parents of new babies and other household members may be the most effective way of preventing the fatal form of whooping cough in young infants, say a group of paediatric intensive care doctors on bmj.com today.

Colorectal cancer rate declines in US
The American Society for Gastrointestinal Endoscopy (ASGE) heralds the recent news of a decline in U.S. cancer deaths and incidence rates, with colorectal cancer among the top three cancers with significant declines.

High blood pressure in doctor's clinic may not predict heart risks
Continuously measuring blood pressure may help predict heart disease and related deaths among individuals with treatment-resistant hypertension, while blood pressure readings taken in a medical clinic do not appear to predict future heart risks, according to a report in November 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

14 drugs identified for off label use
Physicians and policy-makers know that drugs are frequently prescribed to treat certain diseases despite a lack of FDA approval - a practice known as off-label prescribing. Yet they say the problem is so big they don't know how to begin tackling it.

Some breast cancers may regress naturally
Breast cancer rates increased significantly in four Norwegian counties after women there began undergoing mammography every two years, according to a report in the November 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Weight loss maintenance through telephone is effective
Face-to-face and telephone follow-up sessions appear to be more effective in the maintenance of weight loss for women from rural communities compared with weight loss education alone, according to a report in the November 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Children of centenarians live longer with no heart disease, stroke, diabetes
A recent study appearing in the November issue of Journal of American Geriatrics Society revealed that centenarian offspring (children of parents who lived to be at least 97 years old) retain important cardiovascular advantages from their parents compared to a similarly-aged cohort.

Uncertainty more stressful than negative feedback
We are faced with uncertainty every day. Will our investments pay off? Will we get the promotions we are hoping for? When faced with the unknown, most people experience some degree of anxiety and discomfort.

Mesothelioma compensation right defended by Unite the union
In a landmark test case in the High Court, Unite the union, has successfully defended the rights of vulnerable asbestos victims from insurers' attempts to avoid their liabilities.

Hairspray use during pregnancy may cause birth defect in newborn
Women who are exposed to hairspray in the workplace during pregnancy have more than double the risk of having a son with the genital birth defect hypospadias, according to a new study published today in the journal Environmental Health Perspectives.

Laura Bush's partnership for breast cancer awareness in Panama
The University of Texas M. D. Anderson Cancer Center marked the beginning of a collaborative effort to eradicate breast cancer in Panama through the Partnership for Breast Cancer Awareness and Research of the Americas today at an event with Laura Bush, the First Lady of the United States, and Vivian Fernández de Torrijos, the First Lady of Panama.

Asthma risk more in children born in autumn
Children who are born four months before the peak of cold and flu season have a greater risk of developing childhood asthma than children born at any other time of year, according to new research from Vanderbilt University Medical Center.

Routine HIV testing fails in US
While the U.S. AIDS epidemic simmers largely unnoticed by most Americans, a failure to widely implement routine HIV testing continues to fuel its spread, HIV researchers and experts said.

Psychotherapy improves survival for breast cancer patients
A new study finds that breast cancer patients who participate in intervention sessions focusing on improving mood, coping effectively, and altering health behaviors live longer than patients who do not receive such psychological support.

Yeast to identify drugs for Alzheimer's disease
CSIRO scientists have developed a new system to screen for compounds that can inhibit one of the processes that takes place during the progression of Alzheimer's disease.

COPD hospitalizations on the rise in US
A joint report released by the American Lung Association of Minnesota and the Minnesota COPD Coalition shows that chronic obstructive pulmonary disease (COPD) is sending more Minnesotans to the hospital, and may be contributing to rising health care costs across in the state.

Marijuana reduces memory impairment
The more research they do, the more evidence Ohio State University scientists find that specific elements of marijuana can be good for the aging brain by reducing inflammation there and possibly even stimulating the formation of new brain cells.

Ban on fast food TV advertising may reverse childhood obesity trends
A ban on fast food advertisements in the United States could reduce the number of overweight children by as much as 18 percent, according to a new study being published this month in the Journal of Law and Economics.

Genetic screening for diabetes not helpful
Screening for a panel of gene variants associated with the risk for type 2 diabetes can identify adults at risk for the disorder but is not significantly better than assessment based on traditional risk factors such as weight, blood pressure and blood sugar levels.

Transplant of trachea made from stem cells successful
The first operation for transplantation of a tissue-engineered airway has been successful. This procedure has massively improved the quality of life of the 30-year-old Colombian female recipient who needed the transplant after contracting tuberculosis.

Ginkgo biloba does not reduce dementia, Alzheimer's disease risk
The medicinal herb Ginkgo biloba does not reduce the risk of dementia or Alzheimer's disease development in either the healthy elderly or those with mild cognitive impairment, according to a large multicenter trial led by researchers at the University of Pittsburgh School of Medicine.

Birth defects rate high in infants born with assisted reproductive technology
Infants conceived with Assisted Reproductive Technology (ART) are two to four times more likely to have certain types of birth defects than children conceived naturally, according to a study by the CDC.

Secret of sharp memory in old age revealed
Researchers at Northwestern University's Feinberg School of Medicine wondered if the brains of the elderly with still laser sharp memory -- called "super aged" -- were somehow different than everyone else's.

Gardasil HPV vaccine prevented genital lesions in men
GARDASIL [Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant], the cervical cancer vaccine from Merck & Co., Inc., prevented 90 percent of external genital lesions caused by human papillomavirus (HPV) types 6, 11, 16 and 18 in a pivotal Phase III study in men aged 16 to 26.

A man defeated HIV virus through bone marrow transplant
An HIV-positive person, who underwent a bone marrow transplant to treat leukemia, has had undetectable HIV viral loads for almost two years. HIV-positive man was ill from leukemia and had underwent treatment by the team led by Prof. Eckhard Thiel, director of the Medical Clinic with a focus on hematology and oncology.

Vitamin C lowers heart disease biomarker
A new study led by researchers at the University of California, Berkeley, adds to the evidence that vitamin C supplements can lower concentrations of C-reactive protein (CRP), a central biomarker of inflammation that has been shown to be a powerful predictor of heart disease and diabetes.

Single PILL may prevent heart disease
A new clinical trial looking at a single pill to prevent cardiovascular disease is starting in Auckland, New Zealand.

Hannah Jones refused heart transplant surgery
A British girl 13 years old, suffering from leukemia, Hannah Jones decided to refuse to have a heart transplant for her heart condition - a hole in her heart.

Ischemic stroke increases with higher nonfasting triglyceride level
Elevated nonfasting triglyceride levels, previously associated with an increased risk for heart attack, also appear to be associated with an increased risk for ischemic stroke.

Education level linked to Alzheimer's disease, dementia
Individuals with higher education levels appear to score higher on cognitive tests despite having evidence of brain plaques associated with Alzheimer's disease.

Increase in waist circumference increases mortality risk
Having a large waistline can almost double your risk of dying prematurely even if your body mass index is within the 'normal' range, revealed by researchers in a new study.

Influenza Flu trends from Google.org
By tracking the popularity of certain Google search queries, Google's engineers have discovered that they can accurately estimate the level of flu in each state, in near real time.

Ultrasound helps predict heart attacks in low risk patients
By adding the results of an imaging technique to the traditional risk factors for coronary heart disease, doctors at Baylor College of Medicine in Houston found they were able to improve prediction of heart attacks in people previously considered low risk.

Factors identified causing barriers to asthma care
Barriers to managing asthma include access to appropriate care, patient adherence, distrust of the medical profession, delayed asthma diagnosis, culture, lifestyle choices and genetic discrepancies according to experts at the annual meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in Seattle.

Heart may help power pacemakers, defibrillators in heart patients
Surplus energy generated by the heart may one day help power pacemakers and defibrillators implanted in cardiac patients, according to research presented at the American Heart Association’s Scientific Sessions 2008.

Bone marrow transplant can cure sickle cell disease
A unique approach to bone marrow transplantation pioneered in part by a Children's Hospital of Pittsburgh of UPMC physician has proven to be the only safe and effective cure for sickle cell disease, according to a new study.

New risk factor for cardiovascular disease
A team of international researchers - including scientists from the McGill University Health Centre (MUHC) and McGill University - have discovered that having high levels of particular protein puts patients at increased risk of developing cardiovascular disease.

Vitamin B and Folic acid do not appear to affect cancer risk
A daily supplementation combination that included folic acid and vitamin B6 and B12 had no significant effect on the overall risk of cancer, including breast cancer, among women at high risk of cardiovascular disease, according to a study in the November 5 issue of JAMA.

Exercise protects against breast cancer
Normal-weight women who carry out lots of vigorous exercise are approximately 30% less likely to develop breast cancer than those who don't exercise vigorously.

Cost of diabetes treatment doubled in US
Because of the increased number of patients, growing reliance on multiple medications and the shift toward more expensive new medicines, the annual cost of diabetes drugs nearly doubled in only six years, rising from $6.7 billion in 2001 to $12.5 billion in 2007 according to a study in the Oct. 27, 2008, issue of the Archives of Internal Medicine.

Hydrogen sulfide regulates blood pressure
Anyone with a nose knows the rotten-egg odor of hydrogen sulfide, a gas generated by bacteria living in the human colon. Now an international team of scientists has discovered that cells inside the blood vessels of mice - as well as in people, no doubt - naturally make the gassy stuff, and that it controls blood pressure.

Stress may make you itch more
Current research suggests that stress may activate immune cells in your skin, resulting in inflammatory skin disease. The related report by Joachim et al., "Stress-induced Neurogenic Inflammation in Murine Skin Skews Dendritic Cells towards Maturation and Migration: Key role of ICAM-1/LFA-1 interactions," appears in the November issue of The American Journal of Pathology.

Rheumatoid arthritis rising among women in US
After four decades on the decline, rheumatoid arthritis is on the upswing among women in the United States. That's the finding presented by Mayo Clinic investigators at the annual meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals in San Francisco.

HIV infected patients should start HAART sooner
Under current treatment guidelines, highly active antiretroviral therapy (HAART) should be considered for HIV-infected patients when their CD4+ T-cell counts fall below 350 cells per cubic millimeter (mm3).

Chinese exercise Tai chi relieves knee pain
Tai chi is effective in the treatment of pain and physical impairment in people with severe knee osteoarthritis, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in San Francisco, Calif.

Purple, high anthocyanin tomatoes offer protection against certain cancers
Scientists have expressed genes from snapdragon in tomatoes to grow purple tomatoes high in health-protecting anthocyanins.

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