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Violence during childhood may impact kids' DNAChildren who have experienced violence might really be older than their years. The DNA of 10-year-olds who experienced violence in their young lives has been found to show wear and tear normally associated with aging, a Duke University study has found.
HPV DNA testing for all women aged 29 years and aboveImplementation of HPV DNA testing in cervical screening leads to earlier detection of clinically relevant CIN grade 2 or worse, which when adequately treated, improves protection against CIN grade 3 or worse and cervical cancer. Early detection of high-grade cervical legions caused by HPV16 was a major component of this benefit.
5 inherited genetic variants linked to prostate cancerAn international team of researchers led by Fred Hutchinson Cancer Research Center has identified five inherited genetic variants that are strongly associated with aggressive, lethal prostate cancer.
New blood test can detect fetus gender in early pregnancyA boy or a girl baby. Parents-to-be wishing to know the gender of their unborn baby can usually find out during a routine ultrasound performed around 20 weeks of pregnancy. Now, new technology can tell pregnant women whether they are having a boy or a girl as early as seven weeks into a pregnancy. Scientists have been making rapid progress in identifying foetal DNA in the mother's blood to predict fetus gender.
HIV drugs may cause premature agingResearchers revealed that a class of anti-retroviral drugs (NRTIs) commonly used to treat HIV can cause premature ageing, as the drugs damage DNA in the patient's mitochondria. HIV-infected people treated with antiretroviral drugs sometimes show advanced signs of frailty and age-associated diseases such as cardiovascular disease and dementia at an early age.
Autism linked to hundreds of genetic changesInvestigating 1,000 families reveals hundreds of small genetic variations are associated with autism spectrum disorders, according to a multi-site collaborative study led by researchers at Yale University. These genetic findings can be used to begin unraveling the underlying biology of autism.
Swiss US team finds indigenous cases of leprosy in Southern USUsing advanced DNA analysis and extensive field work, an international research team has confirmed the link between leprosy infection in Americans and direct contact with armadillos.
Biomarker test promising for melanoma early diagnosisBiomarker test for DNA methylation is technically feasible and could aid in earlier, more precise diagnosis of melanoma, revealed by US researchers.
New risk factor for developing breast cancerAn Australian research team from the Peter MacCallum Cancer Centre, the University of Melbourne and the University of Queensland has identified a new risk factor for developing breast cancer. This has been published online in the journal Cancer Prevention Research.
New stool test to predict colon cancerAn investigational DNA methylation test could alter the screening landscape for colorectal cancer, according to data presented at the American Association for Cancer Research special conference on Colorectal Cancer: Biology to Therapy, held here Oct. 27-30, 2010.
Genetic variants increase susceptibility to asthmaAn international study looking at DNA from over 26,000 people has identified several genetic variants that substantially increase susceptibility to asthma in the population.
Genetic variant linked to common migraineResearchers have produced new insights into the triggers for migraines attacks. They have identified the first-ever genetic risk factor associated with common types of migraine.
Vitamin B6 lowers risk of lung cancerAn analysis that included nearly 400,000 participants finds that those with higher blood levels of vitamin B6 and the essential amino acid methionine (found in most protein) had an associated lower risk of lung cancer, including participants who were current or former smokers.
New gene linked to Alzheimer's diseaseResearchers have identified a gene that appears to increase a person's risk of developing late-onset Alzheimer's disease, the most common type of Alzheimer's disease.
Isolated DNA Claims are Not Patentable, USA federal judge on Monday struck down patents on two genes -- BRCA1 and BRCA2 -- linked to breast and ovarian cancer. Shares of Myriad Genetics (MYGN.O) fell as much as 7 percent, a day after the ruling.
Creating personalized biomarkers from tumor DNA to treat cancerResearchers have developed a new technique for tracking cancer by identifying personalized biomarkers from tumor DNA, reports a new study in the 24 February 2010 issue of the journal Science Translational Medicine, published by AAAS, the nonprofit science society.
Two new genes identified causing ankylosing spondylitisWork done in part by researchers at The University of Texas Health Science Center at Houston has led to the discovery of two new genes that are implicated in ankylosing spondylitis (AS), an inflammatory and potentially disabling disease.
Human Genome Sequencing decoded in IndiaThe Council of Scientific and Industrial Research (CSIR) has achieved completion of first ever Human Genome Sequencing in India. Scientist of CSIR at the Institute of Genomics and Integrative Biology (IGIB), Delhi have sequenced the Human Genome of an anonymous healthy Indian citizen.
Secondhand smoke exposure increases lung cancer riskChildren exposed to secondhand cigarette smoke have an increased risk of developing lung cancer in adulthood, even if they never smoked.
Genome 10K - to sequence 10000 vertebratesAn international group of scientists is proposing to generate whole genome sequences for 10,000 vertebrate species using technology so new it hasn't yet been invented.
Researchers decoded genetic evolution of a breast cancer tumourCanadian researchers have decoded all of the three billion letters in the DNA sequence of a metastatic lobular breast cancer tumor, a type of breast cancer which accounts for about 10 per cent of all breast cancers.
New biomarker predicts response to hepatitis C treatmentResearchers at Duke University Medical Center have identified the first genetic marker that predicts response to hepatitis C treatments, and a single letter of DNA code appears to make a huge difference.
Schistosomiasis parasite's Schistosoma mansoni's Genome decodedResearchers have sequenced the genome of the parasite -- Schistosoma mansoni -- that causes intestinal schistosomiasis (also known as bilharzia or snail fever), a devastating tropical disease that afflicts more than 200 million people in the developing world.
Study to pinpoint bipolar disorder risk factorsAround 500 Australians aged 12 to 30 will be recruited to take part in a new study to know causes of bipolar disorder and related risk factors, to be conducted in collaboration with four major research institutions in the United States - Johns Hopkins University in Baltimore and the Universities of Michigan, Indiana and Washington.
Schizophrenia linked to common genetic variationsResearchers has discovered that nearly a third of the genetic basis of schizophrenia may be attributed to the cumulative actions of thousands of common genetic variants.
Selenium may worsen prostate cancer in someHigher selenium levels in the blood may worsen prostate cancer in some men who already have the disease, revealed by researchers.
ABCG2 gene mutation causes goutJohns Hopkins scientists out a gene for gout - ABCG2 gene mutation is responsible for causing the joint inflammation and pain that are symptoms of gout.
Cannabis smoke alters human DNA, raising cancer riskCannabis smoke damages DNA in ways that could potentially increase the risk of cancer development in humans, revealed by researchers. The new study published by University of Leicester researchers in the journal Chemical Research in Toxicology.
Graying hairs are signs of stressGraying hairs might be signs of stress, revealed by researchers in a new study. Stress that does damage to DNA decreases amount of melanocyte stem cells (MSCs) within hair follicles that are responsible for making those pigment-producing cells.
New genomic approaches for treating skin diseasesThe health of our skin - one of the body's first lines of defense against illness and injury - depends upon the delicate balance between our own cells and the millions of bacteria and other one-celled microbes that live on its surface.
Shared genetic link between dental disease periodontitis and heart attackThe relationship between the dental disease periodontitis and coronary heart disease (CHD) has been known for several years. Although a genetic link seemed likely, until now its existence was uncertain.
HIV vaccine by using gene transfer technologyA research team may have broken the stubborn impasse that has frustrated the invention of an effective HIV vaccine, by using an approach that bypasses the usual path followed by vaccine developers.
Developing a genetic test for pregnancy risksUniversity of Adelaide researchers are developing a world-first genetic test that can predict which pregnancies are at risk of complications long before symptoms arise.
Autism tied to genes that influence brain cell connectionsResearchers have identified a new gene variant that is highly common in autistic children. Gene, known as CDH10, is most active in key regions that support language, speech and interpreting social behavior.
Cervical cancer screening might safely be delayed after HPV vaccineDNA from human papilloma virus type 16 (HPV16) and HPV type 18 (HPV18) were found in the majority of invasive cervical cancers in New Mexico in the 1980s and 1990s, according to a population-based study published in the March 24 online issue of the Journal of the National Cancer Institute.
Draft version of the Neanderthal genome completedThe Max Planck Institute for Evolutionary Anthropology, in Leipzig, Germany, and the 454 Life Sciences Corporation, in Branford, Connecticut, will announce on 12 February during the 2009 Annual Meeting of the American Association for the Advancement of Science (AAAS) and at a simultaneous European press briefing that they have completed a first draft version of the Neandertal genome.
TV ad to educate women about cervical cancer and HPV testThrough a new advertising campaign being launched in US, local women will soon learn more about cervical cancer screening and prevention.
ATryn from milk of goats approved to treat hereditary antithrombin deficiencyThe U.S. Food and Drug Administration issued its first approval for a biological product produced by genetically engineered (GE) animals.
Animal eggs not suitable to produce stem cellsSince the cloning of Dolly the Sheep over a decade ago, somatic cell nuclear transfer (SCNT) has been considered a promising way to generate human, patient-specific stem cells for therapeutic applications.
Obesity starts in the head?Obesity is known to increase the risk of chronic disorders, such as diabetes (type 2). An international team of scientists with German participation through the Helmholtz Zentrum München identified six new obesity genes.
Few DNA repair genes associated with cancer riskVariants of numerous DNA repair genes initially appeared to be statistically significantly associated with cancer risk in epidemiological studies.
A universal mechanism of aging is identifiedResearchers have discovered that DNA damage decreases a cell's ability to regulate which genes are turned on and off in particular settings. This mechanism, which applies both to fungus and to us, might represent a universal culprit for aging.
New genes identified linked to lung cancerWorking as part of a multi-institutional collaboration, scientists at Washington University School of Medicine in St. Louis have assembled the most complete catalog to date of the genetic changes underlying the most common form of lung cancer.
DNA could reveal your surname and family linksScientists at the world-leading Department of Genetics at the University of Leicester – where the revolutionary technique of genetic fingerprinting was invented by Professor Sir Alec Jeffreys - are developing techniques which may one day allow police to work out someone's surname from the DNA alone.
23andMe announces breast cancer initiative23andMe, Inc., the industry leader in personal genetics, announced that it is embarking on a world-wide effort to assemble the largest cohort of women whose lives have been impacted by breast cancer and to build an infrastructure, based on genetics, that will accelerate consumer-based research of the disease.
Exercise reduces obesity risk in genetically predisposedIndividuals who have a genetic mutation associated with high body mass index (BMI) may be able to offset their increased risk for obesity through physical activity, according to a report in the September 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Chromosomal changes increase schizophrenia riskPeople with schizophrenia (mental illness variously affecting behavior, thinking, and emotion) have an increased number of unusual chromosomal changes, particularly structural changes that have the potential to alter the function of the genes.
First-born babies' have higher asthma and allergy ratesFirst-born children are at higher risk of developing asthma and allergy because of different conditions they experience in the uterus, revealed by researchers.
DNA fingerprinting to identify viable embryos after IVFFertility researchers have used DNA fingerprinting for the first time to identify which embryos have implanted after in vitro fertilisation (IVF) and developed successfully to result in the births of healthy babies.
Genotyping DNA may reduce unnecessary treatment for blood disorder in pregnancyA new test for identifying a mismatch between the blood of a pregnant woman and her baby is accurate, feasible, and could substantially reduce unnecessary treatment, finds a study published on bmj.com.
Genetic errors may cause schizophreniaSchizophrenia, a debilitating psychiatric disorder, is caused by some genetic errors due to deletions and duplications of DNA are more common in people with the mental disorders, revealed by researchers at the University of Washington and Cold Spring Harbor Laboratories.
Short radiotherapy benefits breast cancer patientsA lower total dose of radiotherapy, delivered in fewer, larger treatments has been shown to be as effective as the international standard of a higher total dose delivered over a longer time to treat women with early breast cancer – according to new research published in the Lancet and Lancet Oncology today.
Genentech's Avastin with chemotherapy approved for advanced breast cancerGenentech, Inc. (NYSE: DNA) announced that the U.S. Food and Drug Administration (FDA) granted accelerated approval for Avastin (bevacizumab), in combination with paclitaxel chemotherapy, for the treatment of patients who have not received chemotherapy for their metastatic HER2-negative breast cancer.
Zydus Cadila introduces Nudoxa cancer drugZydus Cadila has introduced an NDDS product 'Nudoxa' for the treatment of various cancers. One of the critical drugs used in chemotherapy, Nudoxa heralds a new approach in cancer therapy.
Avastin found effective in advanced breast cancer patientsGenentech, Inc. (NYSE: DNA) announced that AVADO, a Roche-sponsored Phase III, placebo-controlled study evaluating Avastin® (bevacizumab) in combination with docetaxel chemotherapy met its primary endpoint of prolonging progression-free survival (PFS) in patients who had not received prior chemotherapy for their locally recurrent or metastatic HER2-negative breast cancer.
7 new prostate cancer genetic risk factors identified7 new sites in the human genome identified that are linked to men's risk of developing prostate cancer, revealed by Cancer Research UK funded scientists at the Institute of Cancer Research and University of Cambridge.
Tattooing improves DNA vaccine responseTattooing is a more effective way of delivering DNA vaccines; a tattoo can be more than just a fashion statement – it has potential medical value, according to an article published in the online open access journal, Genetic Vaccines and Therapy.
DNA sequencing found virus killing transplant recipients in AustraliaIn the first application of high throughput DNA sequencing technology to investigate an infectious disease outbreak, link the discovery of a new arenavirus to the deaths of three transplant recipients who received organs from a single donor in Victoria, Australia in April 2007.
Genes linked with lupus giving hope for new treatmentsScientists have identified a number of genes involved in Lupus, a devastating autoimmune disease, in new research published today in the journal Nature Genetics. In an international genetic study of more than 3,000 women, researchers found evidence of an association between Lupus (systemic lupus erythematosus or SLE) and mutations in several different genes.
1000 Genomes Project to support disease studiesAn international research consortium announced the 1000 Genomes Project, an ambitious effort that will involve sequencing the genomes of at least a thousand people from around the world to create the most detailed and medically useful picture to date of human genetic variation.
Genetic testing can gauge prostate cancer riskGenetic testing of DNA in a blood sample can determine which men are likely to develop prostate cancer, as five genetic variants previously associated with prostate cancer risk have a strong cumulative effect.
Mouth rinse gargle test for cancerA morning gargle could someday be more than a breath freshener – it could spot head and neck cancer, say scientists at the Johns Hopkins Kimmel Cancer Center. Their new study of a mouth rinse that captures genetic signatures common to the disease holds promise for screening those at high risk, including heavy smokers and alcohol drinkers.
Breast cancer gene mutation common in Hispanic, young black womenA genetic mutation already known to be more common in Ashkenazi Jewish breast cancer patients is also prevalent in Hispanic and young African-American women with breast cancer, according to one of the largest, multiracial studies of the mutation to date.
63 Dna articles listed above.