Fracture

Calcium, vitamin D may not reduce breast cancer risk
Taking calcium and vitamin D supplements does not reduce breast cancer incidence in postmenopausal women, according to data from a randomized, doubled-blind, placebo-controlled trial published online November 11 in the Journal of the National Cancer Institute.

Merck's Odanacatib increases bone mineral density
2 year data from a Phase IIB study of odanacatib (formerly MK-0822), an investigational, selective cathepsin-K inhibitor in development for the treatment of osteoporosis by Merck & Co., Inc., demonstrated dose-dependent increases in bone mineral density (BMD) at the total hip, lumbar spine and femoral neck fracture sites and decreased indices of bone resorption compared to placebo in postmenopausal women with low BMD.

Diving related injuries common among children
The thrill of flipping and jumping into water has become common practice among children and adolescents as they dive into more than eight million swimming pools across the United States.

Breast cancer spread stopped by bone drug
Researchers at Washington University School of Medicine in St. Louis found that women treated for stage II/III breast cancer who also received a bone strengthening drug zoledronic acid were less likely to have breast tumor cells growing in their bones after three months.

International Cancer Genome Consortium sets sights on cancer
The International Cancer Genome Consortium (ICGC), which includes the Wellcome Trust and the Wellcome Trust Sanger Institute in the UK, will generate a valuable resource enabling the development of new and better ways of diagnosing, treating and preventing cancer.

Keeping in good shape in old age is harder for women
Women aged 65-plus find it harder than men of the same age to preserve muscle - which probably impacts on their ability to stay as strong and fit. For the first time, scientists have shown that it is more difficult for women to replace muscle that is lost naturally as they get older - because of key differences in the way their bodies react to food.

Stem cell therapy trials to mend shattered bones
Scientists are developing a revolutionary way to mend damaged bones and cartilage using a patient's own stem cells.

Calcium supplements may increase heart attacks in postmenopausal women
Calcium is an important component of bone, and a sufficient intake of calcium is needed for bone homoeostasis. Calcium supplements can reduce the risk of fractures in elderly women, but high calcium intakes or calcium supplements may increase the risk of heart attack in healthy postmenopausal women.

Osteoporosis drugs increase bone necrosis risk
A popular class of osteoporosis drugs, bisphosphonates nearly triples the risk of developing bone necrosis, a condition that can lead to disfigurement and incapacitating pain, revealed by researchers in a study. The research conducted by reasearchers at the University of British Columbia and Vancouver Coastal Health Research Institute, Canada.

Women with osteoporosis have increased long-term risk for new fracture
Over a 15 year period, women with low bone mineral density and a previous vertebral fracture had an increased risk of a new vertebral fracture compared to women with normal bone mineral density and no previous fracture, according to a study in the December 19 issue of JAMA.

Predicting hip fracture risk in postmenopausal women
To help doctors predict the five-year risk of hip fractures in their postmenopausal patients, a team of UC Davis researchers has developed a method that assesses nearly a dozen factors, including age, ethnicity and level of physical activity.

Obesity may be bad for bone health
Obesity may be bad for bone health, revealed by researchers at the University of Georgia. Being overweight is a known risk factor for heart disease, diabetes and a host of other health conditions. Now, obesity and over-weight may also be bad for bone health.

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