Gene Variant

Gene Variant - most related articles:

- Gene variant linked to effectiveness of plavix - 5.5
- Gene identified that influences alcohol consumption - 5.5
- Gene Deaf1 may play a role in type 1 diabetes - 5.3
- Omega 3 reduces prostate cancer risk - 5.1
- New asthma gene discovered in African Americans - 5
- Genetic variations transform mild influenza to a life threatening disease - 4.9
- Low body fat may not lower risk for heart disease and diabetes - 4.4
- Selenium may worsen prostate cancer in some - 4.4
- Genes responsible for testicular cancer risk in men - 4.3
- Genetic variants may affect risk of breast cancer - 4.2

Gene Variant articles

10% of ADHD patients linked to GMR gene variants
Pediatric researchers analyzing genetic influences in attention-deficit/hyperactivity disorder (ADHD) have found alterations in specific genes involved in important brain signaling pathways.

5 inherited genetic variants linked to prostate cancer
An international team of researchers led by Fred Hutchinson Cancer Research Center has identified five inherited genetic variants that are strongly associated with aggressive, lethal prostate cancer.

29 new genetic variants linked to multiple sclerosis
Scientists have identified 29 new genetic variants linked to multiple sclerosis, providing key insights into the biology of a very debilitating neurological disease. Many of the genes implicated in the study are relevant to the immune system, shedding light onto the immunological pathways that underlie the development of multiple sclerosis.

New asthma gene discovered in African Americans
A novel gene is discovered associated with the asthma disease in African-Americans and African-Caribbeans. The polymorphism, located in a gene called PYHIN1, was not present in European-Americans and may be the first asthma susceptibility gene variant specific to populations of African descent.

Low body fat may not lower risk for heart disease and diabetes
Researchers revealed that some people with a specific form of the gene are more likely to have lower percent body fat, but also more likely to develop heart disease and type 2 diabetes, because the gene lowers only the "subcutaneous" fat under the skin, but not the more harmful "visceral" fat that surrounds organs. People with this gene variant are less able to store fat safely under the skin and may, therefore, store fat elsewhere in the body, where it may interfere with normal organ function.

Genetic variants may affect risk of breast cancer
An international study led by researchers at Memorial Sloan-Kettering Cancer Center has identified genetic variants in women with BRCA2 mutations that may increase or decrease their risk of developing breast cancer.

Genetic variants increase susceptibility to asthma
An international study looking at DNA from over 26,000 people has identified several genetic variants that substantially increase susceptibility to asthma in the population.

Genetic variant linked to common migraine
Researchers have produced new insights into the triggers for migraines attacks. They have identified the first-ever genetic risk factor associated with common types of migraine.

95 genetic variants linked to cholesterol, triglycerides
Researchers have discovered or confirmed 95 regions of the human genome where genetic variants are associated with blood cholesterol and triglyceride levels, which are major indicators of heart disease risk.

Brain imaging findings in Alzheimer's disease associated with genetic factors
By investigating the association between genetic loci related to Alzheimer's disease and neuroimaging measures related to disease risk, researchers may have uncovered additional evidence that several previously studied genetic variants are associated with the development and progression of Alzheimer's disease and also may have identified new genetic risk factors for further study, according to a report in the June issue of Archives of Neurology, one of the JAMA/Archives journals.

Genetic variants may make people susceptible to autism disorder
Autism is caused in part by rare genetic changes called copy number variants (CNVs), revealed by an international consortium of researchers from more than 70 universities, including the University of Utah.

Gene mutations lead to autism and mental retardation
Researchers working with Professor Gudrun Rappold, Director of the Department of Molecular Human Genetics at Heidelberg University Hospital, have discovered previously unknown mutations in autistic and mentally impaired patients in what is known as the SHANK2 gene, a gene that is partially responsible for linking nerve cells. However, a single gene mutation is not always enough to trigger the illness.

Genetic link between breast density and breast cancer
A University of Melbourne study has revealed that certain breast cancer genetic variants increase mammographic density, confirming the link between mammographic breast density and breast cancer.

Gene linked to aggressive form of prostate cancer
Researchers at Wake Forest University Baptist Medical Center and colleagues have identified the first genetic variant associated with aggressive prostate cancer, proving the concept that genetic information may one day be used in combination with other factors to guide treatment decisions.

New genes for lung disease discovered
Scientists have discovered five genetic variants that are associated with the health of the human lung. The research by an international consortium of 96 scientists from 63 centres in Europe and Australia sheds new light on the molecular basis of lung diseases.

Secondhand smoke exposure increases lung cancer risk
Children exposed to secondhand cigarette smoke have an increased risk of developing lung cancer in adulthood, even if they never smoked.

Gene variant linked to effectiveness of plavix
Patients with a certain genetic variation and who received the antiplatelet drug clopidogrel -- Plavix -- had a decreased platelet response to treatment, revealed by researchers.

Genes linked to blood pressure in African-Americans
Five genetic variants related to blood pressure -- hypertension -- in African-Americans, revealed by a team of researchers from the National Institutes of Health, USA.

Schizophrenia linked to common genetic variations
Researchers has discovered that nearly a third of the genetic basis of schizophrenia may be attributed to the cumulative actions of thousands of common genetic variants.

Infertility linked to genes for earlier menopause
For the first time, scientists have been able to identify genetic factors that influence the age at which natural menopause occurs in women. Ms Lisette Stolk, a researcher from Erasmus MC, Rotterdam, The Netherlands, told the annual conference of the European Society of Human Genetics that a greater understanding of the factors influencing age at menopause might eventually help to improve the clinical treatment of infertile women.

Autism tied to genes that influence brain cell connections
Researchers have identified a new gene variant that is highly common in autistic children. Gene, known as CDH10, is most active in key regions that support language, speech and interpreting social behavior.

Stroke linked to genetic changes
Scientists have identified a previously unknown connection between two genetic variants and an increased risk of stroke, providing strong evidence for the existence of specific genes that help explain the genetic component of stroke.

Omega 3 reduces prostate cancer risk
Omega-3 fatty acids appear protective against advanced prostate cancer, and this effect may be modified by a genetic variant in the COX-2 gene, according to a report in Clinical Cancer Research, a journal of the American Association for Cancer Research.

Gene variants increase hypertension risk
A new study has identified the first common gene variants associated with an increased incidence of hypertension – a significant risk factor for heart attack, stroke and kidney failure.

Multiple sclerosis linked to vitamin D deficiency during pregnancy
Researchers have found evidence that a direct interaction between vitamin D and a common genetic variant alters the risk of developing multiple sclerosis (MS).

Hypertension susceptibility gene STK39 identified
Researchers at the University of Maryland School of Medicine have identified a common gene variant that appears to influence people's risk of developing high blood pressure, according to the results of a study being published online Dec. 29, 2008 in the Proceedings of the National Academy of Sciences (PNAS).

Brain genes linked to BMI, obesity
A genetic study of more than 90,000 people has identified six new genetic variants that are associated with increased Body Mass Index (BMI), the most commonly used measure of obesity. Five of the genes are known to be active in the brain, suggesting that many genetic variants implicated in obesity might affect behaviour, rather than the chemical processes of energy or fat metabolism.

Genetic screening for diabetes not helpful
Screening for a panel of gene variants associated with the risk for type 2 diabetes can identify adults at risk for the disorder but is not significantly better than assessment based on traditional risk factors such as weight, blood pressure and blood sugar levels.

Exercise reduces obesity risk in genetically predisposed
Individuals who have a genetic mutation associated with high body mass index (BMI) may be able to offset their increased risk for obesity through physical activity, according to a report in the September 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Second genetic link to obesity
A study of 90,000 people has uncovered new genetic variants that influence fat mass, weight and risk of obesity. The variants act in addition to the recently described variants of the FTO gene: on average, adults carrying variants in both genes are 3.8 kg (or 8.5 lb) heavier.

Gene variant CHI3L1 increases risk of asthma
A tiny variation in a gene known as CHI3L1 increases susceptibility to asthma, bronchial hyperresponsiveness and decline in lung function, researchers report early online in the New England Journal of Medicine.

Genetic testing can gauge prostate cancer risk
Genetic testing of DNA in a blood sample can determine which men are likely to develop prostate cancer, as five genetic variants previously associated with prostate cancer risk have a strong cumulative effect.

32 Gene Variant articles listed above.

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