Genetic Disease

Genetic Disease - most related articles:

- Strong genetic influence on childhood obesity - 2.4
- Second genetic link to obesity - 2.4
- Genetic variants increase susceptibility to asthma - 2.4
- Brain imaging findings in Alzheimer's disease associated with genetic factors - 2.3
- New gene identified for age related macular degeneration AMD - 2.2
- Gene linked to aggressive form of prostate cancer - 2.2
- Schizophrenia linked to common genetic variations - 2.2
- Shared genetic link between dental disease periodontitis and heart attack - 2.1
- Alzheimer's Society comment on new tau tangle research - 2.1
- Melanoma skin cancer triggered by BRAF gene mutation - 2.1

Genetic Disease articles

Genetic variations transform mild influenza to a life threatening disease
Genetic variations in human body make it more susceptible to diseases. A genetic finding explains why influenza becomes a life-threating disease to some people while it has only mild effects in others.

Understanding working of parkin gene and Parkinson's disease
Parkinson's disease researchers at the University at Buffalo have discovered how mutations in the parkin gene cause the disease, which afflicts at least 500,000 Americans and for which there is no cure. The results are published in the current issue of Nature Communications.

29 new genetic variants linked to multiple sclerosis
Scientists have identified 29 new genetic variants linked to multiple sclerosis, providing key insights into the biology of a very debilitating neurological disease. Many of the genes implicated in the study are relevant to the immune system, shedding light onto the immunological pathways that underlie the development of multiple sclerosis.

Genetic changes may lead to Barrett's esophagus and esophageal cancer
Mutations in three genes have been identified that are more prevalent in patients with esophageal cancer and Barrett esophagus, a premalignant metaplasia (change in cells or tissue) caused by chronic gastroesophageal reflux disease (GERD), according to preliminary research reported in the July 27 issue of JAMA.

Low body fat may not lower risk for heart disease and diabetes
Researchers revealed that some people with a specific form of the gene are more likely to have lower percent body fat, but also more likely to develop heart disease and type 2 diabetes, because the gene lowers only the "subcutaneous" fat under the skin, but not the more harmful "visceral" fat that surrounds organs. People with this gene variant are less able to store fat safely under the skin and may, therefore, store fat elsewhere in the body, where it may interfere with normal organ function.

Combination therapy provides hope for cure of infections in cystic fibrosis
An over-the-counter drug used to treat diarrhea combined with minocycline, an antibiotic used to treat bacterial infections, could one day change the lives of those living with cystic fibrosis.

Genetic drivers C3 and IL-17A linked to severe allergic asthma
Scientists have identified a genetic basis for determining the severity of allergic asthma in experimental models of the disease.

Researchers discover genetic link between immune system, Parkinson's disease
A team of researchers has discovered new evidence that Parkinson's disease may have an infectious or autoimmune origin. "Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease" appears online in Nature Genetics.

Brothers of prostate cancer patients undergo more diagnostic activities
The brothers of men with prostate cancer are at an increased risk of prostate cancer diagnosis because of increased diagnostic activity and not necessarily because they carry a genetic mutation that increases risk of the disease, according to a study published online August 19 in The Journal of the National Cancer Institute.

95 genetic variants linked to cholesterol, triglycerides
Researchers have discovered or confirmed 95 regions of the human genome where genetic variants are associated with blood cholesterol and triglyceride levels, which are major indicators of heart disease risk.

Molecular mechanism triggering Parkinson's disease identified
Scientists at the Stanford University School of Medicine have identified a molecular pathway responsible for the death of key nerve cells whose loss causes Parkinson's disease. This discovery not only may explain how a genetic mutation linked to Parkinson's causes the cells' death, but could also open the door to new therapeutic approaches for the malady.

Genes and Pesticide Exposure increases Parkinson's Disease risk
Genetic mutations and workplace exposure to some insecticides together appear to be associated with an increased risk for Parkinson's disease among men, according to a report in the June issue of Archives of Neurology, one of the JAMA/Archives journals.

Brain imaging findings in Alzheimer's disease associated with genetic factors
By investigating the association between genetic loci related to Alzheimer's disease and neuroimaging measures related to disease risk, researchers may have uncovered additional evidence that several previously studied genetic variants are associated with the development and progression of Alzheimer's disease and also may have identified new genetic risk factors for further study, according to a report in the June issue of Archives of Neurology, one of the JAMA/Archives journals.

New genes for lung disease discovered
Scientists have discovered five genetic variants that are associated with the health of the human lung. The research by an international consortium of 96 scientists from 63 centres in Europe and Australia sheds new light on the molecular basis of lung diseases.

Stem cells to create new skin for patients with burns and skin diseases
Researchers has succeeded in recreating a whole epidermis from human embryonic stem cells, revealed in a new study conducted by Marc Peschanski of INSERM published in the Lancet.

Learn to deal with inattentive, hyperactive & impulsive kids
ADHD is a disorder of the brain and behavior. It affects about 3 to 5% of children. The symptoms start before seven years of age. Global prevalence for children is approximately 5%, with wide variability dependent on research methodologies utilized in studies.

Genes linked to blood pressure in African-Americans
Five genetic variants related to blood pressure -- hypertension -- in African-Americans, revealed by a team of researchers from the National Institutes of Health, USA.

Learning about Alzheimer's disease risk cause no distress
Disclosing genetic risk information to adult children of patients with Alzheimer's disease (AD) who request this information does not result in significant short-term psychological distress, revealed by researchers.

Schizophrenia linked to common genetic variations
Researchers has discovered that nearly a third of the genetic basis of schizophrenia may be attributed to the cumulative actions of thousands of common genetic variants.

Alzheimer's Society comment on new tau tangle research
New research published in Nature Cell Biology suggests that tangle formation can be transferred from one type of trans genetic mouse line to another.

Genes and smoking play role in rheumatoid arthritis
Recent genetic studies have revealed several new sites of genes that are risk factors for developing rheumatoid arthritis (RA), revealed by researchers in the June issue of Arthritis & Rheumatism.

Stem cell - gene therapy may cure human genetic diseases
A study led by researchers at the Salk Institute for Biological Studies, has catapulted the field of regenerative medicine significantly forward, proving in principle that a human genetic disease can be cured using a combination of gene therapy and induced pluripotent stem (iPS) cell technology.

Shared genetic link between dental disease periodontitis and heart attack
The relationship between the dental disease periodontitis and coronary heart disease (CHD) has been known for several years. Although a genetic link seemed likely, until now its existence was uncertain.

Genetic factors may predict depression in heart disease patients
Individuals with heart disease are twice as likely to suffer from depression as the general population, an association the medical community has largely been unable to explain. Now, a new study by researchers at The Miriam Hospital, in conjunction with The Montréal Heart Institute, University of Montréal and McGill University, reveals there may be genetic variations that contribute to depression in heart disease patients.

Genetic factors identified generating new heart cells
Scientists at the Gladstone Institute of Cardiovascular Disease have identified for the first time key genetic factors that drive the process of generating new heart cells.

Women with BRCA mutation most likely to undergo mastectomy
Women at increased risk for breast cancer because of the genetic BRCA mutations are more likely to think a prophylactic mastectomy is the best way to reduce their risk for the disease, compared to other women who are at high risk, according to researchers at The University of Texas M. D. Anderson Cancer Center.

Parkinson's disease linked to melanoma in family
People with a family history of melanoma may have a greater risk of developing Parkinson's disease, according to a study released today that will be presented at the American Academy of Neurology's 61st Annual Meeting in Seattle, April 25 to May 2, 2009.

Parkinson's disease genes linked to manganese poisoning
A connection between genetic and environmental causes of Parkinson's disease has been discovered by a research team led by Aaron D. Gitler, PhD, Assistant Professor in the Department of Cell and Developmental Biology at the University of Pennsylvania School of Medicine.

NPY gene variation may lead to early heart disease
Researchers from Duke University Medical Center have identified a variation in a particular gene that increases susceptibility to early coronary artery disease.

Genetic disease recreated in lab
When neurons started dying in Clive Svendsen's lab dishes, he couldn't have been more pleased. The dying cells – the same type lost in patients with the devastating neurological disease spinal muscular atrophy – confirmed that the University of Wisconsin-Madison stem cell biologist had recreated the hallmarks of a genetic disorder in the lab, using stem cells derived from a patient.

Genetic screening for diabetes not helpful
Screening for a panel of gene variants associated with the risk for type 2 diabetes can identify adults at risk for the disorder but is not significantly better than assessment based on traditional risk factors such as weight, blood pressure and blood sugar levels.

23andMe announces breast cancer initiative
23andMe, Inc., the industry leader in personal genetics, announced that it is embarking on a world-wide effort to assemble the largest cohort of women whose lives have been impacted by breast cancer and to build an infrastructure, based on genetics, that will accelerate consumer-based research of the disease.

Colon cancer's genetic link to obesity
A new study reveals the first-ever genetic link between obesity and colon cancer risk, a finding that could lead to greater accuracy in testing for the disease, said a researcher at the University of Alabama at Birmingham (UAB).

Type 2 diabetes genes associated with prostate cancer
Scientists have identified six new genes which play a role in the development of type 2 diabetes, and among the group is the second gene known to also play a role in prostate cancer.

7 new prostate cancer genetic risk factors identified
7 new sites in the human genome identified that are linked to men's risk of developing prostate cancer, revealed by Cancer Research UK funded scientists at the Institute of Cancer Research and University of Cambridge.

1000 Genomes Project to support disease studies
An international research consortium announced the 1000 Genomes Project, an ambitious effort that will involve sequencing the genomes of at least a thousand people from around the world to create the most detailed and medically useful picture to date of human genetic variation.

Mouth rinse gargle test for cancer
A morning gargle could someday be more than a breath freshener – it could spot head and neck cancer, say scientists at the Johns Hopkins Kimmel Cancer Center. Their new study of a mouth rinse that captures genetic signatures common to the disease holds promise for screening those at high risk, including heavy smokers and alcohol drinkers.

Early treatment stops epilepsy seizures
It is possible to suppress the development of epilepsy in genetically predisposed animals revealed by Yale School of Medicine researchers. This new study would open the door to treating epilepsy as a preventable disease.

38 Genetic Disease articles listed above.

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