Genetic

Genetic - most related articles:

- Strong genetic influence on childhood obesity - 2.4
- Second genetic link to obesity - 2.4
- Genetic variants increase susceptibility to asthma - 2.2
- Physical activity can reduce genetic predisposition to obesity - 2.1
- Schizophrenia linked to common genetic variations - 2
- Genetic defects linked with congenital generalized hypertrichosis - 2

Genetic articles

Depression - now blood test can diagnose depression in teens
A breakthrough approach that allows an objective diagnosis of major depression in teens by measuring a specific set of genetic markers found in a patient's blood. The current method of diagnosing depression is subjective. It relies on the patient's ability to recount his symptoms and the physician's ability and training to interpret them.

Genetic changes in 3 genes linked to autism spectrum disorders
Mutations in three new genes have been linked to autism, according to new studies including one with investigators at Mount Sinai School of Medicine. All three studies include lead investigators of the Autism Sequencing Consortium (ASC).

Breast cancer risk gene can be discovered by massively parallel sequencing
A new technology is developed to fast track the discovery of a breast cancer risk gene and could assist in the discovery of other cancer genes. Now, breast cancer risk gene can be discovered using the latest genetic sequencing technology.

Cancer treatment with personalised approach to cancer patients
Recently researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. They uncovered hundreds of associations between mutations in cancer genes and sensitivity to anticancer drugs.

Genetic variations transform mild influenza to a life threatening disease
Genetic variations in human body make it more susceptible to diseases. A genetic finding explains why influenza becomes a life-threating disease to some people while it has only mild effects in others.

Migraine in mom may increase baby's risk of colic
Mothers who experience migraine may be more likely to have a baby with colic than mothers without a history of migraine. Colic is defined as excessive crying in an otherwise healthy infant.

Understanding working of parkin gene and Parkinson's disease
Parkinson's disease researchers at the University at Buffalo have discovered how mutations in the parkin gene cause the disease, which afflicts at least 500,000 Americans and for which there is no cure. The results are published in the current issue of Nature Communications.

New lung cancer test could accurately guide treatment for people with lung cancer
In the two largest clinical studies ever conducted on the molecular genetics of lung cancer, an international team led by scientists at the University of California, San Francisco (UCSF) has demonstrated that an available molecular test can predict the likelihood of death from early-stage lung cancer more accurately than conventional methods.

10% of ADHD patients linked to GMR gene variants
Pediatric researchers analyzing genetic influences in attention-deficit/hyperactivity disorder (ADHD) have found alterations in specific genes involved in important brain signaling pathways.

Autism linked to gene mutation on chromosome 16
Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered that one of the most common genetic alterations in autism -- deletion of a 27-gene cluster on chromosome 16 -- causes autism-like features.

Asthma can be treated with Tocilizumab rheumatoid arthritis drug
Asthma sufferers now can be treated with a drug used to treat rheumatoid arthritis, revealed by researchers in a new study.

Mesothelioma linked to gene mutation
Individuals who carry a mutation in a gene called BAP1 are susceptible to developing two forms of cancer – mesothelioma, and melanoma of the eye. Mesothelioma tumors are typically associated with asbestos and erionite exposure.

5 inherited genetic variants linked to prostate cancer
An international team of researchers led by Fred Hutchinson Cancer Research Center has identified five inherited genetic variants that are strongly associated with aggressive, lethal prostate cancer.

29 new genetic variants linked to multiple sclerosis
Scientists have identified 29 new genetic variants linked to multiple sclerosis, providing key insights into the biology of a very debilitating neurological disease. Many of the genes implicated in the study are relevant to the immune system, shedding light onto the immunological pathways that underlie the development of multiple sclerosis.

New asthma gene discovered in African Americans
A novel gene is discovered associated with the asthma disease in African-Americans and African-Caribbeans. The polymorphism, located in a gene called PYHIN1, was not present in European-Americans and may be the first asthma susceptibility gene variant specific to populations of African descent.

Genetic changes may lead to Barrett's esophagus and esophageal cancer
Mutations in three genes have been identified that are more prevalent in patients with esophageal cancer and Barrett esophagus, a premalignant metaplasia (change in cells or tissue) caused by chronic gastroesophageal reflux disease (GERD), according to preliminary research reported in the July 27 issue of JAMA.

Environment factors important than genetic in autism
Shared environmental factors – experiences and exposures common to both twin individuals – accounted for 55% of strict autism and 58% of more broadly defined autism spectrum disorders (ASD), revealed by researchers. Genetic heritability accounted for 37% of autism and 38% of ASD.

Low body fat may not lower risk for heart disease and diabetes
Researchers revealed that some people with a specific form of the gene are more likely to have lower percent body fat, but also more likely to develop heart disease and type 2 diabetes, because the gene lowers only the "subcutaneous" fat under the skin, but not the more harmful "visceral" fat that surrounds organs. People with this gene variant are less able to store fat safely under the skin and may, therefore, store fat elsewhere in the body, where it may interfere with normal organ function.

Autism linked to hundreds of genetic changes
Investigating 1,000 families reveals hundreds of small genetic variations are associated with autism spectrum disorders, according to a multi-site collaborative study led by researchers at Yale University. These genetic findings can be used to begin unraveling the underlying biology of autism.

New safety recommendations for high dose 80 mg simvastatin
Patients taking simvastatin 80 mg daily had an increased risk of muscle injury. The risk of muscle injury is highest during the first year of treatment with the 80 mg dose of simvastatin, and is frequently associated with a genetic predisposition for simvastatin-related muscle injury or myopathy.

New class of cancer drugs could work in colon cancers with genetic mutation
A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.

Combination therapy provides hope for cure of infections in cystic fibrosis
An over-the-counter drug used to treat diarrhea combined with minocycline, an antibiotic used to treat bacterial infections, could one day change the lives of those living with cystic fibrosis.

Preventing future bird flu epidemics - GM chickens
Chickens genetically modified to prevent them spreading bird flu have been produced by researchers at the Universities of Cambridge and Edinburgh. They developed a new gene coding that controls bird flu virus progress.

Protein may improve muscle function of muscular dystrophy
A novel potential therapy based on a natural human protein significantly slows muscle damage and improves function in mice who have the same genetic mutation as boys with the most common form of muscular dystrophy, according to a paper published online Dec._27 in the Proceedings of the National Academy of Sciences.

Parents favor genetic testing for melanoma in their children
The vast majority of parents who tested positive for a genetic mutation that increases the risk of melanoma (the most serious form of skin cancer) support genetic testing of their children or grandchildren. Results of the two-year study at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) appear in the December issue of the journal Genetics in Medicine. The data could lead to the establishment of formal, evidence-based guidelines for genetic testing of people younger than 18 years.

Healthy lifestyle choices lower risk of a first stroke 80%
Healthy lifestyle choices and emergency room interventions can help prevent first-time strokes, according to revised American Heart Association/American Stroke Association guidelines.

Genetic test for lung cancer risk prompts smokers to quit
New research shows a gene-based test for lung cancer risk assessment motivates smokers to quit or cut down, according to results of a clinical study presented today at the American Association of Cancer Research's Ninth Annual Conference on Frontiers in Cancer Prevention Research.

Pregnancy related morning sickness could be genetic
Approximately 60,000 pregnant women are hospitalized each year due to hyperemesis gravidarum (HG), an extreme form of nausea and vomiting that endangers their lives and often forces them to reluctantly terminate their pregnancies.

Genetic variants may affect risk of breast cancer
An international study led by researchers at Memorial Sloan-Kettering Cancer Center has identified genetic variants in women with BRCA2 mutations that may increase or decrease their risk of developing breast cancer.

New gene sites linked to obesity and fat distribution
An international consortium has made significant inroads into uncovering the genetic basis of obesity by identifying 18 new gene sites associated with overall obesity and 13 that affect fat distribution.

Genetic patterns may predict osteoarthritis
Scientists from University of North Carolina at Chapel Hill School of Medicine and Interleukin Genetics, Inc. announced findings from a large clinical study to evaluate the role played by genetic factors in the worsening of osteoarthritis.

Genetic variants increase susceptibility to asthma
An international study looking at DNA from over 26,000 people has identified several genetic variants that substantially increase susceptibility to asthma in the population.

Preventive surgeries better in breast or ovarian cancer patients
A long-term study of women with a genetic predisposition for breast or ovarian cancer showed that those who elected major preventive surgeries had a significantly reduced risk of those cancers.

Preventive cancer surgeries save women's lives
A new study underscores the importance for women with a family history of breast or ovarian cancer to get genetic counseling and testing for the BRCA1 and BRCA2 genes that make them more likely to develop lethal breast or ovarian cancer, says a Northwestern Medicine oncologist.

Physical activity can reduce genetic predisposition to obesity
Although the whole population can benefit from a physically active lifestyle, in part through reduced obesity risk, a new study shows that individuals with a genetic predisposition to obesity can benefit even more.

Genetic drivers C3 and IL-17A linked to severe allergic asthma
Scientists have identified a genetic basis for determining the severity of allergic asthma in experimental models of the disease.

Genetic variant linked to common migraine
Researchers have produced new insights into the triggers for migraines attacks. They have identified the first-ever genetic risk factor associated with common types of migraine.

New Parkinson's gene is linked to immune system
A hunt throughout the human genome for variants associated with common, late-onset Parkinson's disease has revealed a new genetic link that implicates the immune system and offers new targets for drug development.

Researchers discover genetic link between immune system, Parkinson's disease
A team of researchers has discovered new evidence that Parkinson's disease may have an infectious or autoimmune origin. "Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease" appears online in Nature Genetics.

Brothers of prostate cancer patients undergo more diagnostic activities
The brothers of men with prostate cancer are at an increased risk of prostate cancer diagnosis because of increased diagnostic activity and not necessarily because they carry a genetic mutation that increases risk of the disease, according to a study published online August 19 in The Journal of the National Cancer Institute.

95 genetic variants linked to cholesterol, triglycerides
Researchers have discovered or confirmed 95 regions of the human genome where genetic variants are associated with blood cholesterol and triglyceride levels, which are major indicators of heart disease risk.

Molecular mechanism triggering Parkinson's disease identified
Scientists at the Stanford University School of Medicine have identified a molecular pathway responsible for the death of key nerve cells whose loss causes Parkinson's disease. This discovery not only may explain how a genetic mutation linked to Parkinson's causes the cells' death, but could also open the door to new therapeutic approaches for the malady.

Genes and Pesticide Exposure increases Parkinson's Disease risk
Genetic mutations and workplace exposure to some insecticides together appear to be associated with an increased risk for Parkinson's disease among men, according to a report in the June issue of Archives of Neurology, one of the JAMA/Archives journals.

Brain imaging findings in Alzheimer's disease associated with genetic factors
By investigating the association between genetic loci related to Alzheimer's disease and neuroimaging measures related to disease risk, researchers may have uncovered additional evidence that several previously studied genetic variants are associated with the development and progression of Alzheimer's disease and also may have identified new genetic risk factors for further study, according to a report in the June issue of Archives of Neurology, one of the JAMA/Archives journals.

Genetic variants may make people susceptible to autism disorder
Autism is caused in part by rare genetic changes called copy number variants (CNVs), revealed by an international consortium of researchers from more than 70 universities, including the University of Utah.

Gene mutations lead to autism and mental retardation
Researchers working with Professor Gudrun Rappold, Director of the Department of Molecular Human Genetics at Heidelberg University Hospital, have discovered previously unknown mutations in autistic and mentally impaired patients in what is known as the SHANK2 gene, a gene that is partially responsible for linking nerve cells. However, a single gene mutation is not always enough to trigger the illness.

Gene test identifies subtypes of breast cancer
A simple genetic test that uses just three genes is among the most effective means of classifying breast cancer into sub-types, US researchers report at the IMPAKT Breast Cancer Conference in Brussels, Belgium.

New gene linked to Alzheimer's disease
Researchers have identified a gene that appears to increase a person's risk of developing late-onset Alzheimer's disease, the most common type of Alzheimer's disease.

BRCA mutation increases breast cancer risk in opposite breast
Women with breast cancer before age 55 who carry an inherited mutation in the breast cancer susceptibility genes BRCA1 or BRCA2 are four times more likely to develop cancer in the breast opposite, or contralateral, to their initial tumor as compared to breast cancer patients without these genetic defects.

Isolated DNA Claims are Not Patentable, US
A federal judge on Monday struck down patents on two genes -- BRCA1 and BRCA2 -- linked to breast and ovarian cancer. Shares of Myriad Genetics (MYGN.O) fell as much as 7 percent, a day after the ruling.

Omega 3 curbs precancerous growths in those prone to bowel cancer
A purified form of an omega 3 cuts the number and size of precancerous bowel growths (polyps) in people whose genetic make-up predisposes them to bowel cancer, finds research published ahead of print in the journal Gut.

Virus hybridization could create pandemic bird flu
Genetic interactions between avian H5N1 influenza and human seasonal influenza viruses have the potential to create hybrid strains combining the virulence of bird flu with the pandemic ability of H1N1, according to a new study.

New tool illuminates connections between stem cells and cancer
Researchers have a new tool to understand how cancers grow -- and with it a new opportunity to identify novel cancer drugs. They've been able to break apart human prostate tissue, extract the stem cells in that tissue, and alter those cells genetically so that they spur cancer.

Genetic link between breast density and breast cancer
A University of Melbourne study has revealed that certain breast cancer genetic variants increase mammographic density, confirming the link between mammographic breast density and breast cancer.

Autistic people don't want hugs
Why do people with fragile X syndrome, a genetic defect that is the best-known cause of autism and inherited mental retardation, recoil from hugs and physical touch – even from their parents?

Two new genes identified causing ankylosing spondylitis
Work done in part by researchers at The University of Texas Health Science Center at Houston has led to the discovery of two new genes that are implicated in ankylosing spondylitis (AS), an inflammatory and potentially disabling disease.

Gene linked to aggressive form of prostate cancer
Researchers at Wake Forest University Baptist Medical Center and colleagues have identified the first genetic variant associated with aggressive prostate cancer, proving the concept that genetic information may one day be used in combination with other factors to guide treatment decisions.

Embryonic stem cell lines lack genetic diversity
The most widely used human embryonic stem cell lines lack genetic diversity, a finding that raises social justice questions that must be addressed to ensure that all sectors of society benefit from stem cell advances, according to a University of Michigan research team.

New genes for lung disease discovered
Scientists have discovered five genetic variants that are associated with the health of the human lung. The research by an international consortium of 96 scientists from 63 centres in Europe and Australia sheds new light on the molecular basis of lung diseases.

Human Genome Sequencing decoded in India
The Council of Scientific and Industrial Research (CSIR) has achieved completion of first ever Human Genome Sequencing in India. Scientist of CSIR at the Institute of Genomics and Integrative Biology (IGIB), Delhi have sequenced the Human Genome of an anonymous healthy Indian citizen.

Kalbitor, ecallantide, approved for treating hereditary angioedema
The U.S. Food and Drug Administration approved Kalbitor (ecallantide) to treat sudden and potentially life-threatening fluid buildup that can occur in people with a rare genetic condition known as hereditary angioedema (HAE).

Ultrasound enhances noninvasive Down syndrome tests
The addition of a "genetic sonogram" maximizes the accuracy of non-invasive testing for Down syndrome, revealed by US researchers.

New Down syndrome treatment suggested by US researchers
Findings from the Stanford University School of Medicine and Lucile Packard Children's Hospital shed light on the neural basis of memory defects in Down syndrome and suggest a new strategy for treating the defects with medication.

Stem cells to create new skin for patients with burns and skin diseases
Researchers has succeeded in recreating a whole epidermis from human embryonic stem cells, revealed in a new study conducted by Marc Peschanski of INSERM published in the Lancet.

Researchers decoded genetic evolution of a breast cancer tumour
Canadian researchers have decoded all of the three billion letters in the DNA sequence of a metastatic lobular breast cancer tumor, a type of breast cancer which accounts for about 10 per cent of all breast cancers.

Learn to deal with inattentive, hyperactive & impulsive kids
ADHD is a disorder of the brain and behavior. It affects about 3 to 5% of children. The symptoms start before seven years of age. Global prevalence for children is approximately 5%, with wide variability dependent on research methodologies utilized in studies.

4 new risk factors for prostate cancer - deCODE genetics
deCODE genetics (Nasdaq:DCGN) announced that a team of its scientists and academic colleagues from Finland, Spain, the Netherlands and the United States have published the discovery of four novel single-letter variations in the sequence of the human genome (SNPs) conferring increased risk of prostate cancer.

Gene variant linked to effectiveness of plavix
Patients with a certain genetic variation and who received the antiplatelet drug clopidogrel -- Plavix -- had a decreased platelet response to treatment, revealed by researchers.

New biomarker predicts response to hepatitis C treatment
Researchers at Duke University Medical Center have identified the first genetic marker that predicts response to hepatitis C treatments, and a single letter of DNA code appears to make a huge difference.

Salinomycin potent against cancer stem cells in breast cancer
A multi-institutional team of Boston-area researchers has discovered a chemical salinomycin that works in mice to kill the rare but aggressive cells within breast cancers that have the ability to seed new tumors.

Women opt surgery to remove breasts, ovaries to reduce cancer risk
Many women at high risk for breast or ovarian cancer are choosing to undergo surgery as a precautionary measure to decrease their cancer risk, revealed by US researchers.

Low birth weight linked to diabetes gene CDKAL1
Gene previously shown to be involved in the development of type 2 diabetes also predisposes children to having a lower birth weight, revealed by researchers.

Prostatectomy effective in men with aggressive prostate cancer
Prostate surgery prostatectomy is found very effective in preventing death in men with aggressive prostate cancers, revealed by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC), Cleveland Clinic and the University of Michigan.

Genetic link to placebo response in depression
In people suffering from major depressive disorder, depression or MDD, genes that influence the brain's reward pathways may modulate the response to placebos, revealed by researchers.

Genes linked to blood pressure in African-Americans
Five genetic variants related to blood pressure -- hypertension -- in African-Americans, revealed by a team of researchers from the National Institutes of Health, USA.

Learning about Alzheimer's disease risk cause no distress
Disclosing genetic risk information to adult children of patients with Alzheimer's disease (AD) who request this information does not result in significant short-term psychological distress, revealed by researchers.

Altered genes play role in development of brain tumors
The interaction between a network of altered genes appears to play an important role in the development and progression of brain tumors, revealed by researchers in the Journal of the American Medical Association -- JAMA.

Melanoma genes identified by Australian researchers
Two new genes that together double a person's risk of developing melanoma are identified by researchers from the Queensland Institute of Medical Research (QIMR), Australia.

Breast cancer's ability to relapse linked to genes
New research led by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) sheds light on a genetic function that gives breast cancer cells the ability to survive and spread to the bone years after treatment has been administered.

Genes linked to moles, melanoma, skin cancer
Why people with the greatest number of moles are at increased risk of the most dangerous form of skin cancer, this puzzle is solved by UK researchers. Their findings are published in the journal Nature Genetics.

Schizophrenia linked to common genetic variations
Researchers has discovered that nearly a third of the genetic basis of schizophrenia may be attributed to the cumulative actions of thousands of common genetic variants.

Depression linked to stressful life events rather genes
Stressful life events are strongly associated with a person's risk for major depression, but a certain gene variation long thought to increase risk in conjunction with stressful life events actually may have no effect.

2 new locations of genes causing multiple sclerosis
Two new locations of genes responsible for multiple sclerosis are discovered which will help to unravel the causes of MS and other autoimmune disease, revealed by Australian and New Zealand researchers

Genetic code mistake causes ovarian cancer
Eureka! Vancouver scientists from the Ovarian Cancer Research (OvCaRe) Program at BC Cancer Agency and Vancouver Coastal Health Research Institute have discovered that there appears to be a single spelling mistake in the genetic code of granulosa cell tumours, a rare and often untreatable form of ovarian cancer.

Lipoprotein a increases heart attack risk
A genetic analysis of data from three studies suggests that genetically elevated levels of lipoprotein(a) are associated with an increased risk of heart attack, according to a study in the June 10 issue of JAMA.

Alzheimer's Society comment on new tau tangle research
New research published in Nature Cell Biology suggests that tangle formation can be transferred from one type of trans genetic mouse line to another.

Parkinson's disease linked to pesticide exposure
The cause of Parkinson's disease (PD), the second most frequent neurodegenerative disease after Alzheimer's disease, is unknown, but in most cases it is believed to involve a combination of environmental risk factors and genetic susceptibility.

Genes and smoking play role in rheumatoid arthritis
Recent genetic studies have revealed several new sites of genes that are risk factors for developing rheumatoid arthritis (RA), revealed by researchers in the June issue of Arthritis & Rheumatism.

Stem cell - gene therapy may cure human genetic diseases
A study led by researchers at the Salk Institute for Biological Studies, has catapulted the field of regenerative medicine significantly forward, proving in principle that a human genetic disease can be cured using a combination of gene therapy and induced pluripotent stem (iPS) cell technology.

Genes responsible for testicular cancer risk in men
Researchers at the University of Pennsylvania School of Medicine have uncovered variation around two genes that are associated with an increased risk of testicular cancer.

Infertility linked to genes for earlier menopause
For the first time, scientists have been able to identify genetic factors that influence the age at which natural menopause occurs in women. Ms Lisette Stolk, a researcher from Erasmus MC, Rotterdam, The Netherlands, told the annual conference of the European Society of Human Genetics that a greater understanding of the factors influencing age at menopause might eventually help to improve the clinical treatment of infertile women.

EUR 6 million to Sahlgrenska Academy for obesity research
The new project is an interdisciplinary research project covering the neurobiological and socio-psychological causes of obesity. It has been awarded EUR 6 million from the EU, corresponding to just over SEK 60 million.

Shared genetic link between dental disease periodontitis and heart attack
The relationship between the dental disease periodontitis and coronary heart disease (CHD) has been known for several years. Although a genetic link seemed likely, until now its existence was uncertain.

A breakthrough in floppy baby syndrome research
In a world first, West Australian scientists have cured mice of a devastating muscle disease that causes a Floppy Baby Syndrome – a breakthrough that could ultimately help thousands of families across the globe.

Genetic defects linked with congenital generalized hypertrichosis
New research provides exciting genetic insight into a rare syndrome that first appeared in the medical literature in the mid 1800s with the case of Julia Pastrana, the world's most notorious bearded lady.

Cancer drugs may treat alcoholism
A class of drugs already approved as cancer treatments might also help to beat alcohol addiction. That's the conclusion of a discovery in flies of a gene, dubbed happyhour, that has an important and previously unknown role in controlling the insects' response to alcohol.

Genetic factors may predict depression in heart disease patients
Individuals with heart disease are twice as likely to suffer from depression as the general population, an association the medical community has largely been unable to explain. Now, a new study by researchers at The Miriam Hospital, in conjunction with The Montréal Heart Institute, University of Montréal and McGill University, reveals there may be genetic variations that contribute to depression in heart disease patients.

Women's menstruation genes identified
Researchers from the Peninsula Medical School, along with collaborators from research institutions across Europe and the United States, have for the first time identified two genes that are involved in determining when girls begin menstruation.

Genetic marker predicts early onset of prostate cancer
Fox Chase Cancer Center researchers have identified a genetic marker that is associated with an earlier onset of prostate cancer in Caucasian men who have a family history of prostate cancer. If the data are confirmed, the marker may help clinicians personalize prostate cancer screening.

Developing a genetic test for pregnancy risks
University of Adelaide researchers are developing a world-first genetic test that can predict which pregnancies are at risk of complications long before symptoms arise.

100 Genetic articles listed above.

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