Human Infection
HPV vaccine's hypersensitivity reactions are rareHypersensitivity reactions to the quadrivalent HPV vaccine (4vHPV, Gardasil) are uncommon and most schoolgirls can tolerate subsequent doses, finds the first evaluation of the quadrivalent HPV vaccine published on bmj.com.
109 medicines, vaccines in development for HIV AIDSAmerica's pharmaceutical research companies are testing 109 medicines and vaccines to treat or prevent HIV/AIDS and related conditions, according to a report released by the Pharmaceutical Research and Manufacturers of America (PhRMA).
£15 m for South Africa in new struggle against AIDSSouth Africa's revitalised drive against AIDS today received a £15 million boost which could help save millions of lives and stop the spread of HIV across the country.
Routine HIV testing fails in USWhile the U.S. AIDS epidemic simmers largely unnoticed by most Americans, a failure to widely implement routine HIV testing continues to fuel its spread, HIV researchers and experts said.
A man defeated HIV virus through bone marrow transplantAn HIV-positive person, who underwent a bone marrow transplant to treat leukemia, has had undetectable HIV viral loads for almost two years. HIV-positive man was ill from leukemia and had underwent treatment by the team led by Prof. Eckhard Thiel, director of the Medical Clinic with a focus on hematology and oncology.
TIM 3 protein turns off HIV fighting T cellsIn HIV-infected patients the body's immune system is unable to fight off the virus. A new study to be published online on November 10th in the Journal of Experimental Medicine shows that T cells in HIV-infected individuals express a protein called TIM-3, which inactivates their virus killing capacity.
HIV infected patients should start HAART soonerUnder current treatment guidelines, highly active antiretroviral therapy (HAART) should be considered for HIV-infected patients when their CD4+ T-cell counts fall below 350 cells per cubic millimeter (mm3).
New MRI imaging may identify cervical cancer earlyUsing high-resolution magnetic resonance imaging (MRI) with a special vaginal coil, a technique to measure the movement of water within tissue, researchers may be able to identify cervical cancer in its early stages, according to a new study being published in the November issue of Radiology.
Estimating lives lost due to delay in HIV drug use in South AfricaMore than 330,000 lives were lost to HIV/AIDS in South Africa from 2000 and 2005 because a feasible and timely antiretroviral (ARV) treatment program was not implemented, assert researchers from the Harvard School of Public Health (HSPH) in a study published online by the Journal of Acquired Immune Deficiency Syndromes (JAIDS) (http://www.jaids.com/).
Antiretrovirals with TB treatment reduces mortality in HIV patientsA South African treatment study conducted by researchers in the Department of Epidemiology at the Mailman School of Public Health shows that mortality among TB-HIV co-infected patients can be reduced by a remarkable 55%, if antiretroviral therapy (ART) is provided with TB treatment at the same time.
Updated labeling for psoriasis drug Raptiva approvedThe U.S. Food and Drug Administration announced labeling changes, including a Boxed Warning, to highlight the risks of life-threatening infections, including progressive multifocal leukoencephalopathy (PML), with the use of Raptiva (efalizumab).
Gardasil vaccine to prevent cervical cancer in IndiaMSD Pharmaceuticals India announced the launch of GARDASIL Vaccine, India's first vaccine to help prevent Cervical Cancer caused by the HPV.
2 doses of flu vaccine needed against bird flu pandemicAn international study led by University of Leicester researchers has determined that vaccination will be the best way to protect people in the event of the next influenza pandemic – but that each person would need two doses.
UN hails recipients of Nobel Prize for discovering HIVThe United Nations has applauded the awarding of the 2008 Nobel Prize for Medicine to two French scientists for their discovery of HIV and for their subsequent pioneering research into the virus.
12 diseases worsened by climate changeHealth experts from the Wildlife Conservation Society released a report that lists 12 pathogens that could spread into new regions as a result of climate change, with potential impacts to both human and wildlife health and global economies.
Brain pathway responsible for obesity discoveredUniversity of Wisconsin-Madison researchers, for the first time, have found a messaging system in the brain that directly affects food intake and body weight.
Indian doctors can't deny HIV+, AIDS patientsIndia's Supreme Court has approved the Indian Govt.'s direction to all States that doctors in government and private hospitals should not refuse treatment to People Living with HIV/AIDS (PLHA).
HIV began spreading among humans between 1884 and 1924New research indicates that the most pervasive global strain of HIV began spreading among humans between 1884 and 1924, suggesting that growing urbanization in colonial Africa set the stage for the HIV/AIDS pandemic.
US to bulk purchase BioThrax anthrax vaccine from Emergent BioSolutionsEmergent BioSolutions Inc. (NYSE:EBS) announced that it has signed a new, multi-year, firm fixed price contract with the U.S. Department of Health and Human Services (HHS) to supply an additional 14.5 million doses of BioThrax(R) (Anthrax Vaccine Adsorbed), its FDA licensed anthrax vaccine, for inclusion in the Strategic National Stockpile (SNS).
QIAGEN's careHPV test provides more accurate screeningA new HPV test developed by QIAGEN specifically for use in regions of the world with scarce resources is "substantially" more accurate in identifying women with cervical disease than the current methods (Pap testing and visual inspection) in these countries.
Poor oral hygiene, bleeding gums may cause heart diseasePeople with poor dental hygiene and those who don't brush their teeth regularly end up with bleeding gums, which provide an entry to the bloodstream for up to 700 different types of bacteria found in our mouths.
Skin odor may diagnose skin cancerChemists described the first identification of a specific "odor profile" for skin cancer, a discovery that could form the basis of a rapid, non-invasive test for diagnosing the most common type of cancer in the United States.
Two HIV/TB global leaders announce merger talksFormal merger negotiations were announced between two global leaders on HIV and TB: Health & Development Networks (HDN) and the International HIV/AIDS Alliance - at the XVII International AIDS Conference which concluded in Mexico on 8_August 2008. The merger will create a new joint organisation with a global mandate, which will be part of the Alliance family.
India to develop HIV AIDS vaccine soonA second Phase I AIDS vaccine clinical trial in India was successfully completed, the Indian Council of Medical Research, the National AIDS Control Organization and the International AIDS Vaccine Initiative announced.
HIV risk high in indian women abused by husbandsMarried women in India who experience physical and sexual violence from their husbands have an increased risk of HIV infection, compared with women who are not abused by their husbands, according to a study in the August 13 issue of JAMA, a theme issue on violence and human rights.
Dr. Ramadoss to Mexico to attend AIDS ConferenceIndian Health Minister Dr. Anbumani Ramadoss, Minister of Health & Family Welfare, Government of India has left for Mexico city and New York on official tour today.
WHO's new HIV AIDS guideAt the XVII International AIDS Conference in Mexico City, the World Health Organization (WHO) launched a package of priority interventions designed to help low- and middle-income countries move towards universal access to HIV/AIDS prevention, treatment, care and support.
International AIDS Society updates treatment guidelines for HIV infectionAn evaluation of recent data has led to an update in the guidelines and recommendations for antiretroviral treatment of adult human immunodeficiency virus (HIV) infection, according to an article in the August 6 issue of JAMA, a theme issue on HIV/AIDS.
Chromosomal changes increase schizophrenia riskPeople with schizophrenia (mental illness variously affecting behavior, thinking, and emotion) have an increased number of unusual chromosomal changes, particularly structural changes that have the potential to alter the function of the genes.
40% higher HIV infection estimate in USThe Centers for Disease Control and Prevention (CDC) is expected soon to increase the estimate of new HIV infections in the United States by 40 percent. This highlights the need to make HIV testing a routine part of medical care and provide better funding to care for those who test positive, according to the HIV Medicine Association (HIVMA).
Genetic variation in Africans raises HIV riskA genetic variation which evolved to protect people of African descent against malaria has now been shown to increase their susceptibility to HIV infection by up to 40 per cent, according to new research. Conversely, the same variation also appears to prolong survival of those infected with HIV by approximately two years.
HPV vaccine Cervarix in UK's immunisation programmeThe UK's leading cervical cancer charity, Jo's Trust, has welcomed the UK's Department of Health's announcement that the HPV vaccine, Cervarix will be used in the national immunisation programme for 12/13 year olds starting in September, 2008.
Oestrogen makes male organ resistant to HIVTopical oestrogen applied to the human penis could stop the spread of HIV, revealed by Australian researchers at the University of Melbourne.
Persistent HPV infection raises cervical cancer riskPersistent infection with human papillomavirus (HPV) could be a useful clinical marker for increased risk of cervical cancer, the second most common cancer in women worldwide, revealed by researchers from the University of North Carolina at Chapel Hill.
OPAL Therapy cost-effective method of treating HIVAustralian researchers have unveiled a new immunotherapy technique to help prevent the progression from HIV infection to AIDS. Details of the simple, cost-effective technique are published May 2nd in the open-access journal PLoS Pathogens.
Mothers less likely to vaccinate daughters against HPVU.S. mothers report they are less likely to vaccinate daughters under age 13 against human papillomavirus virus (HPV), even though the vaccine is recommended for girls at age 11 and 12, it's incumbent upon the healthcare community to work to improve mom's acceptance of the vaccination for younger daughters, say researchers at Cincinnati Children's Hospital Medical Center who conducted the study.
21% children not fully protected against vaccine-preventable diseasesThe U. S. Department of Health and Human Services (HHS) and the Centers for Disease Control and Prevention (CDC) launched National Infant Immunization Week (NIIW) last week.
Monitoring AIDS treatment by physical signs is effectiveWhen millions of HIV-infected people in poor countries began receiving advanced drug therapies, critics worried that patient care would suffer because few high-tech laboratories were available to guide treatments. But according to a study being published in The Lancet, these concerns are as yet unfounded.
New bird flu vaccine may give long-term defenseA new vaccine under development may provide protection against highly pathogenic bird flu and its evolving forms, according to researchers at Purdue University and the Centers for Disease Control and Prevention who discovered the new preventative drug and have tested it in mice.
CD16 monocyte could be a biomarker for progression of HIVAn increase in the CD163+/CD16+ monocyte subset could be a biomarker for the progression of HIV disease, according to researchers at Temple University, reported in the March issue of AIDS Research and Human Retroviruses.
VereFlu portable lab-on-chip for detection of bird fluFollowing the success of the evaluation trials conducted at the prestigious National University Hospital of Singapore, Veredus Laboratories and STMicroelectronics (NYSE: STM) announced the commercial availability of VereFlu, a portable lab-on-chip application for rapid detection of all major influenza types at the point of need.
HIV cases reduced in New ZealandThe New Zealand AIDS Foundation is welcoming the reduction in overall numbers of new HIV diagnoses in 2007, in particular that diagnoses among gay and bisexual men have remained equivalent to 2006 levels.
Alarming rates of STDs among teenage girlsA US study found that one in four teenage girls aged 14 to 19 has a sexually transmitted disease (STD). Nearly half the African-Americans in the study were infected by one of the diseases. The survey, part of the National Health and Nutrition Examination Survey, did not ask about syphilis or gonorrhea, so it is likely the STD rates are actually higher.
HIV AIDS organisations to highlight progress and lessons learnedHIV/AIDS implementers from around the world will gather in Kampala, Uganda, from June 3-7 for the 2008 HIV/AIDS Implementers' Meeting. Recognizing the rapid expansion of HIV/AIDS programs worldwide, the focus of this year's meeting is building the capacity of local prevention, treatment, and care programs; enhancing quality; and promoting coordination among partners.
Avian influenza in West Bengal, no humans affectedIndian Department of Animal Husbandry has notified fresh poultry deaths in Jiaganj and Raghunathganj-II blocks of Murshidabad district of West Bengal on 9th_March, 2008 which has been confirmed as H5 infection of bird flu.
Bird flu resurfaced in West Bengal, IndiaBird flu virus has resurfaced in two blocks of West Bengal's Murshidabad district, prompting authorities to take up culling operations. Culling starts in Raghunathganj-ii and Jiaganj blocks of Murshidabad districts.
Gardasil HPV vaccine reduces abnormal pap test resultsA significant drop in abnormal Pap test results happened after girls and women were given Gardasil vaccine to prevent cervical cancer, according to a researcher at the University of Alabama at Birmingham (UAB).
Race differences affect response to drugs and infectionsDifferences in gene expression levels between people of European versus African ancestry can affect how each group responds to certain drugs or fights off specific infections, report researchers from the University of Chicago Medical Center and the Expression Research Laboratory at Affymetrix Inc. of Santa Clara, CA.
Bird flu awareness campaigns should continue in IndiaThe recent, worst-ever outbreak of the highly pathogenic avian influenza in the Indian state of West Bengal seems to have been brought under control by the swift and comprehensive measures taken by the country's authorities, though continued vigilance was crucial, the United Nations agricultural agency said.
Researchers discover TRIM22 gene that blocks HIVResearchers at the University of Alberta have discovered a gene that is able to block HIV, and in turn prevent the onset of AIDS. Stephen Barr, a molecular virologist in the Department of Medical Microbiology and Immunology, says his team has identified a gene called TRIM22 that can block HIV infection in a cell culture by preventing the assembly of the virus.