Infectious Diseases

HIV infected patients should start HAART sooner
Under current treatment guidelines, highly active antiretroviral therapy (HAART) should be considered for HIV-infected patients when their CD4+ T-cell counts fall below 350 cells per cubic millimeter (mm3).

Estimating lives lost due to delay in HIV drug use in South Africa
More than 330,000 lives were lost to HIV/AIDS in South Africa from 2000 and 2005 because a feasible and timely antiretroviral (ARV) treatment program was not implemented, assert researchers from the Harvard School of Public Health (HSPH) in a study published online by the Journal of Acquired Immune Deficiency Syndromes (JAIDS) (http://www.jaids.com/).

2 doses of flu vaccine needed against bird flu pandemic
An international study led by University of Leicester researchers has determined that vaccination will be the best way to protect people in the event of the next influenza pandemic – but that each person would need two doses.

12 diseases worsened by climate change
Health experts from the Wildlife Conservation Society released a report that lists 12 pathogens that could spread into new regions as a result of climate change, with potential impacts to both human and wildlife health and global economies.

HIV began spreading among humans between 1884 and 1924
New research indicates that the most pervasive global strain of HIV began spreading among humans between 1884 and 1924, suggesting that growing urbanization in colonial Africa set the stage for the HIV/AIDS pandemic.

Travelers' diarrhea vaccine skin patch for travelers
Researchers at The University of Texas School of Public Health have found that patients given a travelers' diarrhea vaccine were significantly less likely to suffer from clinically significant diarrhea than those who received placebo, according to a study published in this week's edition of The Lancet.

Second hand smoke increases infectious diseases risk in infants
Second hand smoke decreases immunity in infants and thereby raises risk of infectious diseases and early hospitalization even in the first year of life in infants, revealed by researchers in the BMJ journal Tobacco Control.

21% children not fully protected against vaccine-preventable diseases
The U. S. Department of Health and Human Services (HHS) and the Centers for Disease Control and Prevention (CDC) launched National Infant Immunization Week (NIIW) last week.

Novel approach to treat Alzheimer's disease
JADO Technologies GmbH, the leading developer of RAFT intervention therapeutics, announced the publication of a paper in Science demonstrating a potential novel strategy for therapeutic intervention in Alzheimer's and other diseases by targeting discrete sub-compartments in the cell membrane (RAFTS).

New bird flu vaccine may give long-term defense
A new vaccine under development may provide protection against highly pathogenic bird flu and its evolving forms, according to researchers at Purdue University and the Centers for Disease Control and Prevention who discovered the new preventative drug and have tested it in mice.

VereFlu portable lab-on-chip for detection of bird flu
Following the success of the evaluation trials conducted at the prestigious National University Hospital of Singapore, Veredus Laboratories and STMicroelectronics (NYSE: STM) announced the commercial availability of VereFlu, a portable lab-on-chip application for rapid detection of all major influenza types at the point of need.

Men prefer meat, women prefer fruits and vegetables
When it comes to what we eat, men and women really are different according to scientific research presented at the 2008 International Conference on Emerging Infectious Diseases in Atlanta, Georgia. In general, men are more likely to report eating meat and poultry items and women are more likely to report eating fruits and vegetables.

MRSA and community acquired staph pneumonia more common
Preliminary research from the Centers for Disease Control and Prevention (CDC) suggests that community acquired pneumonia (CAP) caused by the Staphylococcus aureus bacterium may be more common than originally suspected, including that caused by antibiotic resistant strains.

Schistosomiasis more debilitating than estimated
The health effects of one strain of schistosomiasis, a parasitic disease common in developing countries, are seven to 46 times greater than previously estimated, according to new Brown University research.

Anti HIV gel Tenofovir proven safe for women
An experimental anti HIV gel is safe for women to use on a daily basis, according to researchers at the University of Alabama at Birmingham (UAB) and the University of Pittsburgh School of Medicine.

Emerging infectious diseases are on the rise
A team of scientists has shown that emerging infectious diseases such as HIV, Severe Acute Respiratory Syndrome (SARS), West Nile virus and Ebola are indeed on the rise. The team – including University of Georgia professor John Gittleman and scientists from the Consortium for Conservation Medicine, the Institute of Zoology (London) and Columbia University – recently published their findings in leading scientific journal Nature.

Many maternal deaths worldwide are preventable
Women who die during pregnancy and childbirth in sub-Saharan Africa, more may die from treatable infectious diseases than from conditions directly linked to pregnancy, revealed by researchers.

Herpes virus link to complications in pregnancy
Viral infection with high blood pressure during pregnancy may lead to pre-term birth, revealed by researchers at Adelaide's Women's & Children's Hospital and the University of Adelaide.

Cholesterol lowering drug may fight staph infection
An international team of researchers supported by the National Institutes of Health (NIH) has blocked staph infections in mice using a drug previously tested in clinical trials as a cholesterol-lowering agent. The novel approach, described in the February 14 online edition of Science, could offer a new direction for therapies against a bacterium that's becoming increasingly resistant to antibiotics.

HIV persists in gut despite long term HIV therapy
HIV virus is not usually eradicated from infected individuals even after long term HIV therapy because of the persistence of HIV in hideouts known as viral reservoirs. One important reservoir is the gut, where HIV causes much of its damage due to the large number of HIV target cells that reside there.

Scientists identify new cellular receptor for HIV
A cellular protein that helps guide immune cells to the gut has been newly identified as a target of HIV when the virus begins its assault on the body's immune system, according to researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH).

DNA sequencing found virus killing transplant recipients in Australia
In the first application of high throughput DNA sequencing technology to investigate an infectious disease outbreak, link the discovery of a new arenavirus to the deaths of three transplant recipients who received organs from a single donor in Victoria, Australia in April 2007.

Breastfeeding safer for infants of HIV mothers with Nevirapine
An antiretroviral drug already in widespread use in the developing world to prevent the transmission of HIV from infected mothers to their newborns during childbirth has also been found to substantially cut the risk of subsequent HIV transmission during breast-feeding.

Babies excrete vaccine-mercury quicker
February's issue of Pediatrics offers another reason to rethink blaming the spike in autism diagnoses on thimerosal, a mercury-containing preservative routinely used in several childhood vaccines until the late ‘90s.

Researchers discover a pathway to turn off immune system
University of Minnesota researchers have discovered a new way to turn genes off in human T cells, a type of white blood cell that helps the immune system fight infections. Turning off genes, through a process known as mRNA decay, is important for regulating the body's immune response after fighting infection.

Climate change a threat to human health
Climate change will have a huge impact on human health and bold environmental policy decisions are needed now to protect the world's population, according to the author of an article published in the British Medical Journal (BMJ).

Studies highlight MRSA evolution and resilience
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are caused primarily by a single strain-USA300-of an evolving bacterium that has spread with "extraordinary transmissibility" throughout the United States during the past five years, according to a new study led by National Institutes of Health (NIH) scientists. CA-MRSA, an emerging public health concern, typically causes readily treatable soft-tissue infections such as boils, but also can lead to life-threatening conditions that are difficult to treat.

Climate change a rising risk to health
Climate change could have far-reaching negative impacts on the health of rural Australians, reported in a study co-authored by a Charles Sturt University (CSU) scientist. The report published in the Australian Journal of Rural Health.

New strategies work to put cancer on the firing line
Dr. Yukai He wants to put cancer in the bull's eye. "Cancer really comes from us," the Medical College of Georgia Cancer Center immunologist says of the scary reality that cancer cells are our own cells gone awry. That means our immune system doesn't always see cancer as a horrific invader.

RGS13 protein may play role in suppressing allergic reactions
According to scientists at the National Institute of Allergy and Infectious Diseases (NIAID), a protein in mice known as RGS13 suppresses allergic reactions, including the severe, life-threatening allergic reaction known as anaphylaxis.

$2 million of potentially harmful cosmetic eye product seized in US
At the request of the U.S. Food and Drug Administration, U.S. Marshals seized 12,682 applicator tubes of Age Intervention Eyelash, a product that may, in some users, lead to decreased vision. Authorities said the sales value of the seized tubes is approximately $2 million.

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