Melanoma



Melanoma is a malignant tumour of melanocytes. Melanocytes predominantly occur in the skin but can be found elsewhere, especially the eye. The vast majority of melanomas originate in the skin.


Melanoma - most related articles:

- Melanoma genes identified by Australian researchers - 5.3
- Parkinson's disease linked to melanoma in family - 5.2
- Genes linked to moles, melanoma, skin cancer - 4.9
- Melanoma skin cancer rising in Victoria - 4.9
- Skin cancer cases hit record high, UK - 4.8
- Indoor tanning linked to melanoma - 4.7
- Biomarker test promising for melanoma early diagnosis - 4.6
- New melanoma gene close to be identified - 4.6
- Melanoma skin cancer triggered by BRAF gene mutation - 4.4
- New therapy promising for melanoma skin cancer - 4.2

Melanoma articles

Skin cancer melanoma rising in young adults
Even as the rates of some cancers are falling, Mayo Clinic is seeing an alarming trend: the dramatic rise of skin cancer, especially among people under 40. The incidence of melanoma has escalated, and young women are the hardest hit.

New melanoma drug doubles survival of skin cancer patients
Investigators from Vanderbilt-Ingram Cancer Center (VICC) and 12 other centers in the United States and Australia have found that a new drug for patients with metastatic melanoma nearly doubled median overall survival.

Tanning bed ban for minors under 18 in California US
California Governor Edmund G. Brown, Jr., signed groundbreaking legislation today that will prohibit the use of commercial indoor tanning devices for those under the age of 18. California is the first state to ban minors from using commercial tanning booths.

Mesothelioma linked to gene mutation
Individuals who carry a mutation in a gene called BAP1 are susceptible to developing two forms of cancer – mesothelioma, and melanoma of the eye. Mesothelioma tumors are typically associated with asbestos and erionite exposure.

Zelboraf approved for late stage skin cancer
The U.S. Food and Drug Administration recently approved Zelboraf (vemurafenib), a drug to treat patients with late-stage (metastatic) or unresectable (cannot be removed by surgery) melanoma, the most dangerous type of skin cancer.

Teen girls and young women need a lesson on dangers of indoor tanning
Despite repeated warnings from dermatologists on the health dangers of tanning, results of a new survey by the American Academy of Dermatology (Academy) confirmed that a large percentage of Caucasian teen girls and young women admitted using tanning beds or intentionally tanning outdoors in the past year.

New technique extends cancer fighting cells' potency in melanoma patients
Researchers trained white blood cells to attack tumors tend to fade away quickly when injected into cancer patients.

Biomarker test promising for melanoma early diagnosis
Biomarker test for DNA methylation is technically feasible and could aid in earlier, more precise diagnosis of melanoma, revealed by US researchers.

New drug for melanoma skin cancer patients soon
Plexxikon Inc. announced positive data from an interim analysis of the BRIM3 trial, a large multi-center Phase 3 clinical study of PLX4032 (RG7204) in patients with previously untreated metastatic melanoma with the BRAF mutation.

Follow up helps detect melanoma earlier
A follow-up program for patients at high risk of developing skin cancer appears to be associated with the detection of melanomas at early stages and with good prognosis.

Parents favor genetic testing for melanoma in their children
The vast majority of parents who tested positive for a genetic mutation that increases the risk of melanoma (the most serious form of skin cancer) support genetic testing of their children or grandchildren. Results of the two-year study at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) appear in the December issue of the journal Genetics in Medicine. The data could lead to the establishment of formal, evidence-based guidelines for genetic testing of people younger than 18 years.

International clinical trial tests targeted drug for melanoma skin cancer
Rush University Medical Center has just enrolled the first U.S. patient in an international clinical trial testing a novel drug to treat certain kinds of melanoma, a deadly skin cancer that in its advanced stages currently has few effective treatments.

Celebrex may prevent some non melanoma skin cancers
New research shows the NSAID Celebrex may help prevent some non-melanoma skin cancers from developing in patients who have pre-cancerous actinic keratoses lesions and are at high risk for having the disease.

Advance toward earlier detection of melanoma
Scientists are reporting development of a substance to enhance the visibility of skin cancer cells during scans with an advanced medical imaging system that combines ultrasound and light.

Ipilimumab demonstrates improved survival in metastatic melanoma
Bristol-Myers Squibb Company (NYSE: BMY) announced positive results from a Phase 3 randomized, double blind study of ipilimumab which demonstrated that overall survival (OS) was significantly extended in patients with previously-treated metastatic melanoma who received ipilimumab.

Indoor tanning linked to melanoma
New research from the University of Minnesota's School of Public Health and Masonic Cancer Center definitively links the use of indoor tanning devices to increased risk of melanoma, the most serious form of skin cancer.

Vaccine hope for skin cancer sufferers
Nottingham scientists have been given the green light to test a vaccine which they hope could reverse, and even cure malignant melanoma, the most deadly type of skin cancer.

Wrinkles are scarier than skin cancer for tanners
Researchers link the rapidly rising rates of melanoma and other skin cancers in young women to tanning beds. Researchers tried to find out best way to tell people about bad effects of tanning.

Vitamin D deficiency linked to skin cancer
A Henry Ford Hospital study has shown a link between Vitamin D levels and basal cell carcinoma, a finding that could lead researchers to better understand the development of the most common form of skin cancer.

New treatment for melanoma shows shrinking of tumors
Researchers have made significant advances in the treatment of metastatic malignant melanoma – one of the most difficult cancers to treat successfully once it has started to spread.

Indoor tanning laws should be more stringent, US
Many indoor tanning businesses require parental consent for teenagers to use their facilities, but most would allow young tanners more than the government-recommended amount of exposure during the first week, revealed by researchers.

Breast cancer drug Abraxane promising for malignant melanoma treatment
An approved breast-cancer drug nab-paclitaxel, trade named Abraxane, has been found promising in clinical trial for the treatment of metastatic malignant melanoma, revealed by researchers.

Melanoma genes identified by Australian researchers
Two new genes that together double a person's risk of developing melanoma are identified by researchers from the Queensland Institute of Medical Research (QIMR), Australia.

Genes linked to moles, melanoma, skin cancer
Why people with the greatest number of moles are at increased risk of the most dangerous form of skin cancer, this puzzle is solved by UK researchers. Their findings are published in the journal Nature Genetics.

Stem cells improve sight for sore eyes
In a world-first breakthrough, University of New South Wales (UNSW) medical researchers have used stem cells cultured on a simple contact lens to restore sight to sufferers of blinding corneal disease.

Immunotherapy with vaccine improves advanced melanoma
A vaccine for one of the most lethal cancers, advanced melanoma, has shown improved response rates and progression-free survival for patients when combined with the immunotherapy drug, Interleukin-2, according to researchers from The University of Texas M. D. Anderson Cancer Center.

Zebrafish provide a model for cancerous melanoma in humans
In a new study published in Disease Models & Mechanisms, scientists use the zebrafish to gain insight into the influence of known cancer genes on the development and progression of melanoma, an aggressive form of human skin cancer with limited treatment options.

Skin cancer cases hit record high, UK
The number of people diagnosed with the deadliest form of skin cancer has crashed through the 10,000 barrier after an alarming rise in new cases, according to the latest Cancer Research UK figures.

Skin cancer knowledge lacking in people
Pale skinned people who are most at risk of skin cancer are ignoring sun safety advice, according to research released to launch Sun Awareness Week 2009.

Early detection of skin cancer melanoma is vital
On television's popular "Grey's Anatomy," Dr. Izzie Stevens faces a grim diagnosis: stage IV metastatic melanoma. As the drama unfolds, viewers get a glimpse at why patients with the deadliest form of skin cancer – in the most advanced stage of diagnosis – face a mere 10-month median survival rate.

Skin cancer melanoma screeing in older men
Older men whose melanoma is detected by a physician are more likely to have thinner and therefore more treatable tumors at diagnosis, according to results of a survey published in the April issue of Archives of Dermatology, one of the JAMA/Archives journals.

Melanoma skin cancer triggered by BRAF gene mutation
Up to 70 per cent of melanoma skin cancers could be triggered by a particular genetic mutation, according to a study by The Institute of Cancer Research (ICR) published in Cancer.

Outdoor workers exposed to higher ultraviolet radiation
Outdoor workers in New Zealand are exposed to much higher levels of ultraviolet radiation from the summer sun than internationally recommended occupational exposure limits, a new University of Otago study suggests.

Parkinson's disease linked to melanoma in family
People with a family history of melanoma may have a greater risk of developing Parkinson's disease, according to a study released today that will be presented at the American Academy of Neurology's 61st Annual Meeting in Seattle, April 25 to May 2, 2009.

Melanoma skin cancer linked to mental stress
For patients with a particularly aggressive form of skin cancer malignant melanoma stress, including that which comes from simply hearing that diagnosis, might amplify the progression of their disease.

Abraxis BioScience to Create Abraxis Health - Pioneering Personalized Medicine
Abraxis BioScience, Inc. (NASDAQ:ABII), a fully integrated, global biotechnology company, announced that the Board of Directors has approved a strategic plan to create Abraxis Health, Inc., an independent, stand-alone company to be spun-off from Abraxis BioScience that will be dedicated to becoming a fully integrated, next-generation, evidence-based, personalized healthcare company.

Moisturisers may increase skin cancer risk
Moisturisers used by millions of people may be increasing the risk of common skin cancer like melanoma, hinted by researchers. However, the researchers had cautioned that the experiments were carried out on mice, but the majority of moisturisers have not gone through skin cancer safety checks.

New therapy promising for melanoma skin cancer
The combination of two different biotherapies (interferon alfa-2b and tremelimumab) may be beneficial for patients with inoperable melanoma, revealed by researchers in US.

New melanoma gene close to be identified
The researchers are close to discovering a new gene that could help explain variation in melanoma risk. They have identified a region on chromosome 20 (20q11.22) that influences a person's risk of developing melanoma.

International Cancer Genome Consortium sets sights on cancer
The International Cancer Genome Consortium (ICGC), which includes the Wellcome Trust and the Wellcome Trust Sanger Institute in the UK, will generate a valuable resource enabling the development of new and better ways of diagnosing, treating and preventing cancer.

Melanoma skin cancer rising in Victoria
New figures from The Cancer Council Victoria show that the number of Victorians affected by melanoma is at the highest level ever. Latest figures from the Victorian Cancer Registry show that in 2005, melanoma overtook lung cancer and is now the fourth most common cause of cancer in Victorians.

IGFBP7 protein may stop melanoma skin cancer
Howard Hughes Medical Institute (HHMI) researchers have uncovered a protein that stops the growth of melanoma, a cancer that develops from pigment-producing cells in the skin called melanocytes.

Melanomas may appear different than other moles
A preliminary study suggests that melanomas have a different appearance than other irregular skin moles (i.e., are "ugly ducklings"), according to a report in the January issue of Archives of Dermatology, one of the JAMA/Archives journals.

New strategies work to put cancer on the firing line
Dr. Yukai He wants to put cancer in the bull's eye. "Cancer really comes from us," the Medical College of Georgia Cancer Center immunologist says of the scary reality that cancer cells are our own cells gone awry. That means our immune system doesn't always see cancer as a horrific invader.

44 Melanoma articles listed above.


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What is Melanoma
Melanoma is a malignant tumour of melanocytes. Melanocytes predominantly occur in the skin but can be found elsewhere, especially the eye. The vast majority of melanomas originate in the skin.



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