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Mole - most related articles:

- Skin cancer knowledge lacking in people - 3.6
- New therapy promising for melanoma skin cancer - 3.2
- Melanoma genes identified by Australian researchers - 2.4
- Zebrafish provide a model for cancerous melanoma in humans - 2.2

Mole articles

Circadian rhythms linked to sudden cardiac attack
A new study uncovers the first molecular evidence linking the body's natural circadian rhythms to sudden cardiac death (SCD). Ventricular arrhythmias, or abnormal heart rhythms, are the most common cause of sudden cardiac death: the primary cause of death from heart disease. They occur most frequently in the morning waking hours, followed by a smaller peak in the evening hours.

New lung cancer test could accurately guide treatment for people with lung cancer
In the two largest clinical studies ever conducted on the molecular genetics of lung cancer, an international team led by scientists at the University of California, San Francisco (UCSF) has demonstrated that an available molecular test can predict the likelihood of death from early-stage lung cancer more accurately than conventional methods.

Nicotine primes brain for drug abuse like cocaine
Cigarettes and alcohol serve as gateway drugs, which people use before progressing to the use of marijuana and then to cocaine and other illicit substances; this progression is called the "gateway sequence" of drug use.

Depression uncouples brain's hate circuit
Depression frequently seems to uncouple the brain's "Hate Circuit". The study entitled "Depression Uncouples Brain Hate Circuit" is published in the journal Molecular Psychiatry.

Eating grapes and drinking red wine protect your skin
UV radiation leads to the generation of reactive oxygen species (ROS). These molecules exert a variety of harmful effects by altering key cellular functions and may result in cell death. Several studies have demonstrated that human skin can be protected against UV radiation by using plant-derived antioxidants.

Autism changes molecular structure of brain
A new UCLA study is the first to reveal how the autism disorder makes its mark at the molecular level, resulting in an autistic brain that differs dramatically in structure from a healthy one.

Blueberries may inhibit development of fat cells in obese
Using blueberry polyphenols, researcers were able to inhibit obesity at a molecular stage. The study was performed in tissue cultures taken from mice. The polyphenols showed a dose-dependent suppression of adipocyte differentiation.

Elevations in 5 amino acids metabolite may predict diabetes risk
Measuring the levels of small molecules in the blood may be able to identify individuals at elevated risk of developing type 2 diabetes as much as a decade before symptoms of the disorder appear.

Gene based prostate cancer test may make more accurate treatment decisions
Researchers conducted an elaborate series of experiments to identify the genes most closely linked to the aggressive biology of prostate cancer. They found about 300 genes that distinguished the two groups - indolent versus aggressive prostate cancers.

Biomarker test promising for melanoma early diagnosis
Biomarker test for DNA methylation is technically feasible and could aid in earlier, more precise diagnosis of melanoma, revealed by US researchers.

Imaging can identify biomarker of alzheimer's disease
Preliminary research suggests that use of a type of molecular imaging procedure may have the ability to detect the presence of beta-amyloid in the brains of individuals during life, a biomarker that is identified during autopsy to confirm a diagnosis of Alzheimer disease.

A new way to test blood for Alzheimer's disease
Using a new technology that relies on thousands of synthetic molecules to fish for disease-specific antibodies, researchers have developed a potential method for detecting Alzheimer's disease with a simple blood test.

Molecular mechanism triggering Parkinson's disease identified
Scientists at the Stanford University School of Medicine have identified a molecular pathway responsible for the death of key nerve cells whose loss causes Parkinson's disease. This discovery not only may explain how a genetic mutation linked to Parkinson's causes the cells' death, but could also open the door to new therapeutic approaches for the malady.

Salsa and guacamole important causes of foodborne disease
Nearly 1 out of every 25 restaurant-associated foodborne outbreaks with identified food sources between 1998 and 2008 can be traced back to contaminated salsa or guacamole, more than double the rate during the previous decade.

Acupuncture's molecular effects pinned down
Scientists have taken another important step toward understanding just how sticking needles into the body can ease pain. In a paper published online May_30 in Nature Neuroscience, a team at the University of Rochester Medical Center identifies the molecule adenosine as a central player in parlaying some of the effects of acupuncture in the body.

Gene mutations lead to autism and mental retardation
Researchers working with Professor Gudrun Rappold, Director of the Department of Molecular Human Genetics at Heidelberg University Hospital, have discovered previously unknown mutations in autistic and mentally impaired patients in what is known as the SHANK2 gene, a gene that is partially responsible for linking nerve cells. However, a single gene mutation is not always enough to trigger the illness.

Green tea may reduce lung cancer risk in smokers
Drinking green tea could modulate the effect of smoking on lung cancer. Results of this hospital-based, randomized study conducted in Taiwan were presented at the AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer, held here from Jan_11-14, 2010.

Study provides insight into pathway linked to obesity
A new study involving the University of Iowa, Mayo Clinic and two other institutions provides insight on weight control, suggesting that a ATP-sensitive potassium channel critical to survival and stress adaptation can contribute to fat deposition and obesity.

New genes for lung disease discovered
Scientists have discovered five genetic variants that are associated with the health of the human lung. The research by an international consortium of 96 scientists from 63 centres in Europe and Australia sheds new light on the molecular basis of lung diseases.

Gene therapy may improve vision in congenital blindness LCA
Researchers from the University of Pennsylvania School of Medicine and the Center for Cellular and Molecular Therapeutics at the Children's Hospital of Philadelphia have used gene therapy to safely improve vision in five children and seven adults with a rare form of congenital blindness.

Diabetes may weaken your bones
The inflammatory molecule TNF-a may contribute to delayed bone fracture healing in diabetics, revealed by researchers. Diabetes, a condition where the body either does not produce enough, or respond to, insulin, affects at least 171 million people worldwide, a figure that is likely to double by 2030.

Melanoma genes identified by Australian researchers
Two new genes that together double a person's risk of developing melanoma are identified by researchers from the Queensland Institute of Medical Research (QIMR), Australia.

Genes linked to moles, melanoma, skin cancer
Why people with the greatest number of moles are at increased risk of the most dangerous form of skin cancer, this puzzle is solved by UK researchers. Their findings are published in the journal Nature Genetics.

Neratinib shows promise in trastuzumab resistant breast cancer
Fox Chase Cancer Center researchers report that a combination of trastuzumab and neratinib (HKI-272) a novel small molecule inhibitor of the HER2 receptor (ErbB2) appears active in women with HER2-positive metastatic breast cancer who have progressed on previous trastuzumab based therapies.

AMP joins ACLU to challenge BRCA gene patents
The Association for Molecular Pathology (AMP) announced that it is working with the American Civil Liberties Union (ACLU) and the Public Patent Foundation to bring a lawsuit charging that patents on two human genes associated with breast and ovarian cancer are unconstitutional and should be invalidated.

Gene p18 defects linked to breast cancer
The discovery of tumor-suppressor genes has been key to unlocking the molecular and cellular mechanisms leading to uncontrolled cell proliferation – the hallmark of cancer.

Skin cancer knowledge lacking in people
Pale skinned people who are most at risk of skin cancer are ignoring sun safety advice, according to research released to launch Sun Awareness Week 2009.

New drug aims to transform malaria treatment
Ranbaxy Laboratories Limited (Ranbaxy) announced the commencement of Phase-III clinical trials for its new Anti-malaria combination drug, Arterolane maleate + Piperaquine phosphate in India, Bangladesh and Thailand.

Antioxidants for free radicals may not stop aging
For more than 40 years, the prevailing explanation of why we get old has been tied to what is called oxidative stress. This theory postulates that when molecules like free radicals, oxygen ions and peroxides build up in cells, they overwhelm the cells' ability to repair the damage they cause, and the cells age.

A-beta clearance - a key to treatment or prevention of Alzheimer's disease
In Alzheimer's disease the brain accumulates a molecule called A-beta that can be quite toxic to brain cells. Many researchers believe that finding ways to clear A-beta may be a key to treatment or prevention of Alzheimer's disease.

New test to predict chemotherapy response in breast cancer patients
Researchers at the Swiss Institute of Bioinformatics and the Swiss National Center of Competence in Research in Molecular Oncology in Lausanne have developed a new test to predict how breast cancer patients respond to chemotherapy, which could help change how treatment is delivered in the future.

Brain senses fatty food
In the battle against obesity, Yale University researchers may have discovered a new weapon - a naturally occurring molecule secreted by the gut that makes rats and mice less hungry after fatty meals.

Gut bacteria helps control body weight and obesity
A single molecule in the intestinal wall, activated by the waste products from gut bacteria, plays a large role in controlling whether the host animals are lean or fatty, a research team, including scientists from UT Southwestern Medical Center, has found in a mouse study.

Chemotherapy target found for leukemia
Cancer researchers at the Stanford University School of Medicine have discovered a promising new chemotherapy target for a deadly form of leukemia. Their discovery hinges on a novel "double agent" role for a molecular signal that regulates cell growth.

Broccoli may help heart in diabetes patients
Researchers claim that a compound found in brassica vegetables such as broccoli could undo the damage caused by diabetes to heart blood vessels.

New research will help identify risk factors for SIDS
Sudden Infant Death Syndrome or SIDS is a condition that unexpectedly and unexplainably takes the lives of seemingly healthy babies aged between a month and a year. Now researchers of the European Molecular Biology Laboratory in Monterotondo, Italy, have developed a mouse model of the so-called crib or cot death, which remains the leading cause of death during the first year of life in developed countries.

New therapy promising for melanoma skin cancer
The combination of two different biotherapies (interferon alfa-2b and tremelimumab) may be beneficial for patients with inoperable melanoma, revealed by researchers in US.

VereFlu portable lab-on-chip for detection of bird flu
Following the success of the evaluation trials conducted at the prestigious National University Hospital of Singapore, Veredus Laboratories and STMicroelectronics (NYSE: STM) announced the commercial availability of VereFlu, a portable lab-on-chip application for rapid detection of all major influenza types at the point of need.

Researchers discover TRIM22 gene that blocks HIV
Researchers at the University of Alberta have discovered a gene that is able to block HIV, and in turn prevent the onset of AIDS. Stephen Barr, a molecular virologist in the Department of Medical Microbiology and Immunology, says his team has identified a gene called TRIM22 that can block HIV infection in a cell culture by preventing the assembly of the virus.

Laser to detect potential diseases via breath
By blasting a person's breath with laser light, scientists from the National Institute of Standards and Technology and the University of Colorado at Boulder have shown that they can detect molecules that may be markers for diseases like asthma or cancer.

Tattooing improves DNA vaccine response
Tattooing is a more effective way of delivering DNA vaccines; a tattoo can be more than just a fashion statement – it has potential medical value, according to an article published in the online open access journal, Genetic Vaccines and Therapy.

IGFBP7 protein may stop melanoma skin cancer
Howard Hughes Medical Institute (HHMI) researchers have uncovered a protein that stops the growth of melanoma, a cancer that develops from pigment-producing cells in the skin called melanocytes.

Melanomas may appear different than other moles
A preliminary study suggests that melanomas have a different appearance than other irregular skin moles (i.e., are "ugly ducklings"), according to a report in the January issue of Archives of Dermatology, one of the JAMA/Archives journals.

RNA may stop breast cancer spread
Now, researchers can develop more effective drugs to prevent or treat cancer metastasis, as they have identified a specific group of microRNA molecules that are responsible for controlling genes that cause breast cancer metastasis.

Protein may trigger insulin production in diabetic patients
If the human body were a stage, then proteins would rank among the lead actors in the play we call "Life." These large biological molecules hold many starring roles, and their lines are dictated by information encoded in our genes. They are production powerhouses, regulating the basic processes of living and controlling countless functions. Many are enzymes that produce or use energy. Others regulate genes.

New test to detect and identify 12 respiratory viruses
The U.S. Food and Drug Administration has approved a new diagnostic test that detects 12 respiratory viruses, including strains of flu that have triggered epidemics.

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