Oncology

Oncology - most related articles:

- Prostate cancer family history has no impact on treatment - 2.6
- Ginger quells post chemotherapy nausea in cancer patients - 2.4
- Thalidomide does not improve survival in lung cancer - 2.3
- Acupuncture relieves hot flashes from prostate cancer treatment - 2.2
- Genomic sequencing of difficult breast cancers - 2.2
- Gleevec improves special leukemia in children - 2.2
- Math may predict Herceptin response in breast cancer patients - 2.2
- Understanding chronic myeloid leukemia - 2.2
- Simple blood test may detect ovarian cancer early - 2
- Anti smoking law helps waiters to quit smoking - 2

Oncology articles

New lung cancer test could accurately guide treatment for people with lung cancer
In the two largest clinical studies ever conducted on the molecular genetics of lung cancer, an international team led by scientists at the University of California, San Francisco (UCSF) has demonstrated that an available molecular test can predict the likelihood of death from early-stage lung cancer more accurately than conventional methods.

Cost of cancer care rising worldwide
Cancer is one of the leading causes of death and morbidity worldwide, and its economic burden grows year by year. In 2008, the worldwide cost of cancer due to premature death and disability, excluding direct medical costs, was estimated to be US$895 billion.

Novartis drug Afinitor everolimus helps advanced breast cancer women
A pivotal Phase III study shows Afinitor (everolimus) tablets plus exemestane, a hormonal therapy, more than doubled the time women lived without tumor growth (progression-free survival; PFS) and significantly reduced the risk of cancer progression by 57% versus exemestane alone in patients with advanced breast cancer.

IUDs may lower cervical cancer risk
IUDs or intrauterine contraceptive devices could substantially reduce the risk of women developing cervical cancer, revealed by researchers in a recent study in Lancet Oncology.

Radiation improves survival in breast cancer surgery patients
Additional radiation treatment improves disease free survival lessening the chance of cancer recurring in women with early breast cancer who have had breast conserving surgery (lumpectomy), interim results of a new study found. The results will be presented Monday, June_6 at the annual meeting of the American Society of Clinical Oncology.

Pfizer drug reduces breast cancer in high risk women
The drug exemestane significantly reduces the risk of breast cancer in high-risk, postmenopausal women is the result of an international, randomized double-blind phase III clinical trial in which University at Buffalo researchers and hundreds of Western New York women played a critical role, revealed at the American Society of Clinical Oncology annual meeting.

Acupuncture relieves hot flashes from prostate cancer treatment
Acupuncture provides long-lasting relief to hot flashes, heart palpitations and anxiety due to side effects of the hormone given to counteract testosterone, the hormone that induces prostate cancer, according to a study published in the April issue of the International Journal of Radiation Oncology•Biology•Physics, an official journal of the American Society for Radiation Oncology (ASTRO).

Closely monitoring better for low risk prostate cancer
A Johns Hopkins study of 769 men from across the United States recently diagnosed with low-grade prostate cancer shows that forgoing immediate surgery to remove the tumor or radiation poses no added risk of death.

Adoption of newer, more expensive prostate cancer treatments
With 180,000 men diagnosed with prostate cancer each year, it is one of the most common types of cancer in US. For this reason, it has been cited as a good marker for health care spending in general, reflective of the greater trends across the United States.

Age plays too big a role in prostate cancer treatment decisions
Older men with high-risk prostate cancer frequently are offered fewer – and less effective – choices of treatment than younger men, potentially resulting in earlier deaths, according to a new UCSF study.

Pancreatic cancers progress to lethal stage slowly
Pancreatic cancer develops and spreads much more slowly than scientists have thought, according to new research from Johns Hopkins investigators.

Discussing patient safety in radiation therapy
A meeting in Miami this week will bring together some of the world's leading experts from inside and outside the clinic to discuss safety in radiation therapy -- a critical method for treating cancer.

Exercise may keep cancer patients healthier
Breast and prostate cancer patients who regularly exercise during and after cancer treatment report having a better quality of life and being less fatigued, according to researchers at Henry Ford Hospital in Detroit.

Estrogen lowering drugs minimize surgery in breast cancer patients
A US study has confirmed the benefit of giving estrogen-lowering drugs before surgery to breast cancer patients. The treatment increased the likelihood that women could undergo breast-conservation surgery, also called lumpectomy, instead of mastectomy.

Simple blood test may detect ovarian cancer early
Researchers find out that CA-125 protein may help detact ovarian cancer in its early stage. The findings were presented by Karen Lu, M.D., professor in MD Anderson's Department of Gynecologic Oncology, in advance of the American Society of Clinical Oncology (ASCO) annual meeting.

BRCA mutation increases breast cancer risk in opposite breast
Women with breast cancer before age 55 who carry an inherited mutation in the breast cancer susceptibility genes BRCA1 or BRCA2 are four times more likely to develop cancer in the breast opposite, or contralateral, to their initial tumor as compared to breast cancer patients without these genetic defects.

Genomic sequencing of difficult breast cancers
Life Technologies Corporation (NASDAQ: LIFE) announced that it is collaborating with the Translational Genomics Research Institute (TGen) and US Oncology to sequence the genomes of 14 patients afflicted with triple negative breast cancer whose tumors have progressed despite multiple other therapies.

Symptoms have little value to diagnose ovarian cancer earlier
Use of symptoms to trigger a medical evaluation for ovarian cancer does not appear to detect early-stage ovarian cancer earlier and would likely result in diagnosis in only 1 out of 100 women in the general population with such symptoms, revealed in an article.

Cancer mortality declined in Europe
New figures on deaths from cancer in Europe show a steady decline in mortality between the periods 1990-1994 and 2000-2004. Deaths from all cancers in the European Union (EU) between these two periods fell by nine percent in men and eight percent in women, with a large drop among the middle-aged population.

Few questions can determine risk for lung cancer
Aa simple questionnaire designed to identify patients at high risk of lung cancer is found helpful. The new study is featured in the November issue of the Journal of Thoracic Oncology.

FDA declines Fusilev NDA for colorectal cancer
A Complete Response letter is issued by the U.S. Food and Drug Administration (FDA) regarding the supplemental New Drug Application (sNDA) for FUSILEV (levoleucovorin) for injection for treatment of patients with advanced metastatic colorectal cancer.

Researchers decoded genetic evolution of a breast cancer tumour
Canadian researchers have decoded all of the three billion letters in the DNA sequence of a metastatic lobular breast cancer tumor, a type of breast cancer which accounts for about 10 per cent of all breast cancers.

Anti smoking law helps waiters to quit smoking
Researchers from the Catalan Institute of Oncology have studied the impact of the law banning smoking in public places such as bars and restaurants on those working in these places.

Math may predict Herceptin response in breast cancer patients
Cancer researchers are turning to mathematical models to help answer important clinical questions, and a new paper in Cancer Research, a journal of the American Association for Cancer Research, illustrates how the technique may answer questions about Herceptin resistance.

Breast cancer drug Abraxane promising for malignant melanoma treatment
An approved breast-cancer drug nab-paclitaxel, trade named Abraxane, has been found promising in clinical trial for the treatment of metastatic malignant melanoma, revealed by researchers.

Thalidomide does not improve survival in lung cancer
Treating patients with thalidomide in combination with chemotherapy for small cell lung cancer (SCLC) did not improve their survival but did increase their risk of blood clots, revealed by researchers.

New consensus on using APBI to treat breast cancer
A new consensus statement outlining patient selection criteria and best practices for the use of accelerated partial breast irradiation (APBI) outside the context of a clinical trial has been published in the July 15 issue of the International Journal of Radiation Oncology Biology Physics.

Vandetanib with docetaxel improve lung cancer survival
When combined with standard chemotherapy, an international Phase III trial has shown that the oral targeted therapy vandetanib improves progression-free survival for patients with advanced non-small cell lung cancer, according to research from The University of Texas M. D. Anderson Cancer Center.

Low income breast cancer patients skipping hormonal therapy
Many low-income women are failing to take the hormonal therapy prescribed as part of their breast cancer treatment, possibly lowering their survival rates, according to a study led by a researcher in the Duke Comprehensive Cancer Center.

Ginger quells post chemotherapy nausea in cancer patients
People with cancer can reduce post-chemotherapy nausea by 40 percent by using ginger supplements, along with standard anti-vomiting drugs, before undergoing treatment, according to scientists at the University of Rochester Medical Center.

Genetic marker predicts early onset of prostate cancer
Fox Chase Cancer Center researchers have identified a genetic marker that is associated with an earlier onset of prostate cancer in Caucasian men who have a family history of prostate cancer. If the data are confirmed, the marker may help clinicians personalize prostate cancer screening.

Triple drug combination promising to treat breast cancer
Combining two chemotherapy drugs with trastuzumab (Herceptin) to treat women who have metastatic HER2+ breast cancer may offer physicians another choice in their treatment options.

Embryo's heartbeat drives blood stem cell formation
Biologists have long wondered why the embryonic heart begins beating so early, before the tissues actually need to be infused with blood. Two groups of researchers from Children's Hospital Boston, Brigham and Women's Hospital, and the Harvard Stem Cell Institute (HSCI) -– presenting multiple lines of evidence from zebrafish, mice and mouse embryonic stem cells -– provide an intriguing answer: A beating heart and blood flow are necessary for development of the blood system, which relies on mechanical stresses to cue its formation.

A tiny drop of blood helps to assess cancer details
A drop of blood or a chunk of tissue smaller than the period at the end of this sentence may one day be all that is necessary to diagnose cancers and assess their response to treatment, say researchers at the Stanford University School of Medicine.

Women with BRCA mutation most likely to undergo mastectomy
Women at increased risk for breast cancer because of the genetic BRCA mutations are more likely to think a prophylactic mastectomy is the best way to reduce their risk for the disease, compared to other women who are at high risk, according to researchers at The University of Texas M. D. Anderson Cancer Center.

New genomic test to personalize breast cancer treatment
A set of 50 genes can be used to reliably identify the four known types of breast cancer, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions.

Pregnancy has no impact on breast cancer diagnosis and treatment
Young women who develop breast cancer during their pregnancy, or who are diagnosed within one year of their pregnancy, have no difference in rates of local recurrence, distant metastases and overall survival compared to other young women with the disease, according to researchers at The University of Texas M. D. Anderson Cancer Center.

New test to predict chemotherapy response in breast cancer patients
Researchers at the Swiss Institute of Bioinformatics and the Swiss National Center of Competence in Research in Molecular Oncology in Lausanne have developed a new test to predict how breast cancer patients respond to chemotherapy, which could help change how treatment is delivered in the future.

Preventive mastectomy decision for breast cancer patient
A preventive procedure to remove the unaffected breast in breast cancer patients with disease in one breast may only be necessary in patients who have high-risk features as assessed by examining the patient's medical history and pathology of the breast cancer, according to researchers at The University of Texas M. D. Anderson Cancer Center.

Prostate cancer family history has no impact on treatment
Family history of prostate cancer does not affect some prostate cancer patient's treatment outcomes, revealed by researchers.

Smoking increases colorectal cancer risk
An analysis of previous studies indicates that smoking is significantly associated with an increased risk for colorectal cancer and death, according to an article in the December 17 issue of JAMA.

Healthy diet may cut risk of breast cancer recurrence
A secondary analysis of a large, multicenter clinical trial has shown that a diet loaded with fruits, vegetables and fiber and somewhat lower in fat compared to standard federal dietary recommendations cuts the risk of recurrence in a subgroup of early-stage breast cancer survivors – women who didn't have hot flashes – by approximately 31 percent.

Laura Bush's partnership for breast cancer awareness in Panama
The University of Texas M. D. Anderson Cancer Center marked the beginning of a collaborative effort to eradicate breast cancer in Panama through the Partnership for Breast Cancer Awareness and Research of the Americas today at an event with Laura Bush, the First Lady of the United States, and Vivian Fernández de Torrijos, the First Lady of Panama.

A man defeated HIV virus through bone marrow transplant
An HIV-positive person, who underwent a bone marrow transplant to treat leukemia, has had undetectable HIV viral loads for almost two years. HIV-positive man was ill from leukemia and had underwent treatment by the team led by Prof. Eckhard Thiel, director of the Medical Clinic with a focus on hematology and oncology.

1 week radiation effective breast cancer treatment
Accelerated partial breast irradiation (APBI) using a type of radiation seed implants called balloon brachytherapy is as effective in keeping breast cancer from coming back as the standard external beam radiation treatment.

Acupuncture reduces side effects of breast cancer treatment
Acupuncture is as effective and longer-lasting in managing the common debilitating side effects of hot flashes, night sweats, and excessive sweating (vasomotor symptoms) associated with breast cancer treatment and has no treatment side effects compared to conventional drug therapy, according to a first-of-its-kind study presented September 24, 2008, at the American Society for Therapeutic Radiology and Oncology's 50th Annual Meeting in Boston.

QIAGEN's careHPV test provides more accurate screening
A new HPV test developed by QIAGEN specifically for use in regions of the world with scarce resources is "substantially" more accurate in identifying women with cervical disease than the current methods (Pap testing and visual inspection) in these countries.

Lumpectomy, radiation improve life in breast cancer patients
Women with breast cancer who are treated with lumpectomy and radiation report a high level of overall quality of life several years after treatment that is comparable to a general sampling of the adult women U.S. population according to a survey conducted by physicians at Fox Chase Cancer Center.

New therapy promising for melanoma skin cancer
The combination of two different biotherapies (interferon alfa-2b and tremelimumab) may be beneficial for patients with inoperable melanoma, revealed by researchers in US.

Short radiotherapy benefits breast cancer patients
A lower total dose of radiotherapy, delivered in fewer, larger treatments has been shown to be as effective as the international standard of a higher total dose delivered over a longer time to treat women with early breast cancer – according to new research published in the Lancet and Lancet Oncology today.

Novartis' Femara protects against breast cancer return
Women may reduce the risk of their breast cancer returning by starting treatment with Femara (letrozole) anywhere from one to seven years after finishing tamoxifen therapy, according to a new analysis published in the Journal of Clinical Oncology.

Gardasil HPV vaccine reduces abnormal pap test results
A significant drop in abnormal Pap test results happened after girls and women were given Gardasil vaccine to prevent cervical cancer, according to a researcher at the University of Alabama at Birmingham (UAB).

Researchers identify protein that fuels ovarian cancer
A protein that stimulates blood vessel growth worsens ovarian cancer, but its production can be stifled by a tiny bit of RNA wrapped in a fatty nanoparticle, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Journal of the National Cancer Institute.

Uninsured diagnosed with an advanced stage cancer
A new American Cancer Society study of twelve types of cancer among more than 3.5 million cancer patients finds uninsured patients were significantly more likely to present with advanced stage cancer compared to patients with private insurance.

Gene therapy promising for chronic pain relief
Now, chronic pain can be successfully treated with novel targeted gene therapy. In an effort to find a more effective treatment for chronic pain, researchers at Mount Sinai developed a gene therapy technique that simulates the pain-killing effect of opiate drugs.

RNA may stop breast cancer spread
Now, researchers can develop more effective drugs to prevent or treat cancer metastasis, as they have identified a specific group of microRNA molecules that are responsible for controlling genes that cause breast cancer metastasis.

Lung cancer cells' survival gene 14-3-3zeta seen as drug target
One of the deadliest forms of cancer appears to carry a specific weakness. When a key gene called 14-3-3zeta is silenced, lung cancer cells can't survive on their own, researchers have found.

Test for targeted therapy in acute myeloid leukemia
An Oregon Health & Science University Cancer Institute researcher has discovered that a particular hormone is responsible for driving a cancer enzyme to cause an often deadly red blood cell cancer.

Gleevec improves special leukemia in children
Gleevec, the targeted cancer pill that has saved more than 100,000 lives, now is saving more children with a dire leukemia, as well as preventing disease progression with long term use in adults with chronic myeloid leukemia.

Understanding chronic myeloid leukemia
Oregon Health & Science University Cancer Institute researchers have opened a new window into the roots of chronic myeloid leukemia (CML). "We are looking under the surface of CML to understand better where the cancer is coming from. We have discovered abnormal cells in the early stem cell population in some CML patients, which don't belong to the CML clone. These are abnormal cells that are not part of the CML clone," said Thomas Bumm, M.D., OHSU Cancer Institute member.

Night shift work may cause cancer
A study by the World Health Organization has found that night shift work increases the risk of cancer in humans. The study found that after prolonged exposure to night shift work, women are at a higher risk to develop breast and colon cancer. Men who work the night shift are more likely to experience prostate cancer.

Nexavar approved for patients with inoperable liver cancer
The U.S. Food and Drug Administration has approved Nexavar (sorafenib) for use in patients with a form of liver cancer known as hepatocellular carcinoma, when the cancer is inoperable. Nexavar was originally approved in 2005 for the treatment of patients with advanced renal cell carcinoma, a form of kidney cancer.

62 Oncology articles listed above.

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