Osteoporosis

The word osteoporosis literally means "porous bones." It occurs when bones lose an excessive amount of their protein and mineral content, particularly calcium. Over time, bone mass, and therefore bone strength, is decreased. As a result, bones become fragile and break easily. Even a sneeze or a sudden movement may be enough to break a bone in someone with severe osteoporosis.


Cost of diabetes treatment doubled in US
Because of the increased number of patients, growing reliance on multiple medications and the shift toward more expensive new medicines, the annual cost of diabetes drugs nearly doubled in only six years, rising from $6.7 billion in 2001 to $12.5 billion in 2007 according to a study in the Oct. 27, 2008, issue of the Archives of Internal Medicine.

Rheumatoid arthritis rising among women in US
After four decades on the decline, rheumatoid arthritis is on the upswing among women in the United States. That's the finding presented by Mayo Clinic investigators at the annual meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals in San Francisco.

Merck's Odanacatib increases bone mineral density
2 year data from a Phase IIB study of odanacatib (formerly MK-0822), an investigational, selective cathepsin-K inhibitor in development for the treatment of osteoporosis by Merck & Co., Inc., demonstrated dose-dependent increases in bone mineral density (BMD) at the total hip, lumbar spine and femoral neck fracture sites and decreased indices of bone resorption compared to placebo in postmenopausal women with low BMD.

Red wine may ward off effects of age on heart, bones, eyes and muscles
Large doses of a red wine ingredient can ward off many of the vagaries of aging in mice who begin taking it at midlife, according to a new report published online on July 3rd in Cell Metabolism, a Cell Press publication. Those health improvements of the chemical known as resveratrol-including cardiovascular benefits, greater motor coordination, reduced cataracts and better bone density-come without necessarily extending the animals' lifespan.

Rheumatoid arthritis risk higher in people with high birth weight
People who have a birth weight over 10 pounds are twice as likely to develop rheumatoid arthritis when they are adults compared to individuals born with an average birth weight, according to a study published by researchers from Hospital for Special Surgery online in advance of print in the Annals of the Rheumatic Diseases.

Breast cancer spread stopped by bone drug
Researchers at Washington University School of Medicine in St. Louis found that women treated for stage II/III breast cancer who also received a bone strengthening drug zoledronic acid were less likely to have breast tumor cells growing in their bones after three months.

Healthy lifestyle for long life
A healthy lifestyle during the early elderly years-including weight management, exercising regularly and not smoking-may be associated with a greater probability of living to age 90 in men, as well as good health and physical function, according to a report in the February 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Sedentary lifestyles linked to early aging
Physical inactivity is an important risk factor for many aging-related diseases. Individuals who are physically active during their leisure time appear to be biologically younger than those with sedentary lifestyles, according to a report in the January 28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Kids food still full of salt, says CASH
Many foods eaten by UK children still contain large amounts of salt, in some cases more than half the daily maximum limit for a 6 year old in a single serving, revealed by researchers. Research carried out with Netmums, a leading parenting website, also shows that many parents are confused about which foods contain salt.

Osteoporosis drugs increase bone necrosis risk
A popular class of osteoporosis drugs, bisphosphonates nearly triples the risk of developing bone necrosis, a condition that can lead to disfigurement and incapacitating pain, revealed by researchers in a study. The research conducted by reasearchers at the University of British Columbia and Vancouver Coastal Health Research Institute, Canada.

Genetically modified carrots provide more calcium for osteoporosis patients
A specially developed carrot has been produced to help people absorb more calcium. Researchers studied the calcium intake of humans who ate the carrot and found a net increase in calcium absorption. Adding this carrot to the diet can help prevent such diseases as osteoporosis.

Oral osteoporosis medicines safe during dental work
Some doctors and dentists had advised patients who take oral osteoporosis medications such as Fosamax and Boniva to postpone dental work, fearing that tooth extractions and other procedures would exacerbate jaw problems purportedly linked to the medication. But the new findings refute the link and suggest the benefits of dentistry likely outweigh the risks for many of these patients.

Quit Smoking – a Healthy Start to 2008
The Australian Medical Association AMA is urging all smokers to put their health first in 2008 by making a New Year's resolution to quit smoking for good.

Women with osteoporosis have increased long-term risk for new fracture
Over a 15 year period, women with low bone mineral density and a previous vertebral fracture had an increased risk of a new vertebral fracture compared to women with normal bone mineral density and no previous fracture, according to a study in the December 19 issue of JAMA.

Predicting hip fracture risk in postmenopausal women
To help doctors predict the five-year risk of hip fractures in their postmenopausal patients, a team of UC Davis researchers has developed a method that assesses nearly a dozen factors, including age, ethnicity and level of physical activity.

Obesity may be bad for bone health
Obesity may be bad for bone health, revealed by researchers at the University of Georgia. Being overweight is a known risk factor for heart disease, diabetes and a host of other health conditions. Now, obesity and over-weight may also be bad for bone health.

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