Osteoporosis

The word osteoporosis literally means "porous bones." It occurs when bones lose an excessive amount of their protein and mineral content, particularly calcium. Over time, bone mass, and therefore bone strength, is decreased. As a result, bones become fragile and break easily. Even a sneeze or a sudden movement may be enough to break a bone in someone with severe osteoporosis.

Osteoporosis - most related articles:

- Prolia - new injectable osteoporosis treatment for postmenopausal women - 4.8
- Merck's Odanacatib increases bone mineral density - 4.4
- Bone density related to bone erosion in rheumatoid arthritis patients - 4.2
- Oral osteoporosis medicines safe during dental work - 4
- Calcium supplements may increase heart attack risk - 3.9
- Label change expected for osteoporosis drugs Fosamax, Actonel and Boniva - 3.9
- Osteoporosis drug may improve immune system - 3.7
- Increasing daily calcium will not reduce fracture risk in later life - 3.7
- Osteoporosis drugs increase bone necrosis risk - 3.5
- Bone density unnecessary in women taking osteoporosis drugs - 3.3

Osteoporosis articles

63% women suffer from some knee pain
63% of women age 50 and older reported persistent, incident, or intermittent knee pain during a 12-year study period, revealed by researchers. Predictors for persistent pain included higher body mass index (BMI), previous knee injury, and radiographic osteoarthritis (OA).

Pfizer new drug could provide a new treatment option for postmenopausal women
Pfizer Inc. will announce new one-year results from the Selective estrogens, Menopause, And Response to Therapy [SMART]-5 Phase 3 study of the safety and efficacy of the investigational tissue selective estrogen complex (TSEC) bazedoxifene/conjugated estrogens (BZA/CE) at the 22nd annual meeting of the North American Menopause Society (NAMS), September_21-24 in Washington, D.C.

Label change expected for osteoporosis drugs Fosamax, Actonel and Boniva
A US FDA advisory committee wants the health agency FDA to limit the duration of bisphosphonate therapy for treatment of osteoporosis. The panel could not agree on what that time limit should be. The panel also endorsed a label change for osteoporosis drugs.

Increasing daily calcium will not reduce fracture risk in later life
While moderate amounts of calcium (around 700 mg a day) are vital for maintaining healthy bones, there is no need to start increasing calcium intake in order to reduce the risk of fractures or osteoporosis in later life, finds a paper published in bmj.

Drugs for epilepsy increases fracture risk in older
Most anti-epileptic drugs are associated with an increased risk of non-traumatic fracture in individuals 50 years of age and older, revealed by researchers in a study published in the Archives of Neurology.

New rheumatoid arthritis criteria aim to recognise RA early
New criteria for rheumatoid arthritis (RA), published in the Annals of Rheumatic Diseases, could prevent thousands of people from developing disabling late stage disease, by redefining how RA should be classified.

Calcium supplements may increase heart attack risk
Calcium supplements, commonly taken by older people for osteoporosis, are associated with an increased risk of a heart attack, revealed by researchers. The results suggest that a reassessment of the role of calcium supplements in osteoporosis management is needed.

Prolia - new injectable osteoporosis treatment for postmenopausal women
The U.S. Food and Drug Administration approved Prolia, an injectable treatment for postmenopausal women with osteoporosis who are at high risk for fractures.

Osteoporosis drugs linked to atypical fractures
Bisphosphonate treatments, proven to enhance bone density and reduce fracture incidence in post-menopausal women, may adversely affect bone quality and increase risk of atypical fractures of the femur when used for four or more years.

Fat mass helps build bone mass in girls
According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), fat mass is important in increasing bone size and thickness, but this effect appears to be stronger in girls than boys.

Breast cancer drugs may prevent cervical cancer also
Researchers eliminated cervical cancer in mice with two FDA-approved drugs currently used to treat breast cancer and osteoporosis. The study is published in the Proceedings of the National Academy of Sciences.

Osteoporosis drug may improve immune system
An osteoporosis drug zoledronic acid (Reclast) proven to save lives after hip fractures may do so by strengthening the body's immune system, revealed by geriatrics researchers at Duke University Medical Center.

Bone density related to bone erosion in rheumatoid arthritis patients
A new study has examined the relationship between two rheumatoid arthritis related processes i.e. focal erosions and osteoporosis, in the hopes of providing insight into the underlying pathophysiology of RA-related bone disease.

Bone density unnecessary in women taking osteoporosis drugs
Monitoring bone mineral density in postmenopausal women taking osteoporosis drugs (bisphosphonates) is unnecessary and potentially misleading, revealed by researchers through a new study published on bmj.com.

Sick patients tend to have low Vitamin D
A group of endocrinologists in Sydney have observed that very sick patients tend to have very low levels of Vitamin D. The sicker they are, the lower the levels.

Osteoporosis drug boost bone's healing process
Osteoporosis drug teriparatide or Forteo can boost bodies' bone stem cell production to the point that adults' bones appear to have the ability to heal at a rate typically seen when they were young kids, revealed by researchers.

Osteoporotic fracture risky in older adults
Women and men age 60 years or older who have a low-trauma osteoporotic fracture have an increased risk of death for the following 5 to 10 years, compared to the general population, and those who experience another fracture increase their risk of death further for an additional 5 years, according to a study in the February 4 issue of JAMA.

Rheumatoid arthritis worse in women
Women appear to suffer more from rheumatoid arthritis (RA) than men. This is revealed in research published in BioMed Central's open access journal Arthritis Research and Therapy.

Jaw necrosis risk from oral bisphosphonate, Fosomax
A new research study revealed that there an increased risk jaw necrosis from oral bisphosphonates like Fossamax type drugs used for osteoporosis.

Rheumatoid arthritis rising among women in US
After four decades on the decline, rheumatoid arthritis is on the upswing among women in the United States. That's the finding presented by Mayo Clinic investigators at the annual meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals in San Francisco.

Merck's Odanacatib increases bone mineral density
2 year data from a Phase IIB study of odanacatib (formerly MK-0822), an investigational, selective cathepsin-K inhibitor in development for the treatment of osteoporosis by Merck & Co., Inc., demonstrated dose-dependent increases in bone mineral density (BMD) at the total hip, lumbar spine and femoral neck fracture sites and decreased indices of bone resorption compared to placebo in postmenopausal women with low BMD.

Breast cancer spread stopped by bone drug
Researchers at Washington University School of Medicine in St. Louis found that women treated for stage II/III breast cancer who also received a bone strengthening drug zoledronic acid were less likely to have breast tumor cells growing in their bones after three months.

Sedentary lifestyles linked to early aging
Physical inactivity is an important risk factor for many aging-related diseases. Individuals who are physically active during their leisure time appear to be biologically younger than those with sedentary lifestyles, according to a report in the January 28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Kids food still full of salt, says CASH
Many foods eaten by UK children still contain large amounts of salt, in some cases more than half the daily maximum limit for a 6 year old in a single serving, revealed by researchers. Research carried out with Netmums, a leading parenting website, also shows that many parents are confused about which foods contain salt.

Osteoporosis drugs increase bone necrosis risk
A popular class of osteoporosis drugs, bisphosphonates nearly triples the risk of developing bone necrosis, a condition that can lead to disfigurement and incapacitating pain, revealed by researchers in a study. The research conducted by reasearchers at the University of British Columbia and Vancouver Coastal Health Research Institute, Canada.

Genetically modified carrots provide more calcium for osteoporosis patients
A specially developed carrot has been produced to help people absorb more calcium. Researchers studied the calcium intake of humans who ate the carrot and found a net increase in calcium absorption. Adding this carrot to the diet can help prevent such diseases as osteoporosis.

Oral osteoporosis medicines safe during dental work
Some doctors and dentists had advised patients who take oral osteoporosis medications such as Fosamax and Boniva to postpone dental work, fearing that tooth extractions and other procedures would exacerbate jaw problems purportedly linked to the medication. But the new findings refute the link and suggest the benefits of dentistry likely outweigh the risks for many of these patients.

Quit Smoking – a Healthy Start to 2008
The Australian Medical Association AMA is urging all smokers to put their health first in 2008 by making a New Year's resolution to quit smoking for good.

Women with osteoporosis have increased long-term risk for new fracture
Over a 15 year period, women with low bone mineral density and a previous vertebral fracture had an increased risk of a new vertebral fracture compared to women with normal bone mineral density and no previous fracture, according to a study in the December 19 issue of JAMA.

Predicting hip fracture risk in postmenopausal women
To help doctors predict the five-year risk of hip fractures in their postmenopausal patients, a team of UC Davis researchers has developed a method that assesses nearly a dozen factors, including age, ethnicity and level of physical activity.

Obesity may be bad for bone health
Obesity may be bad for bone health, revealed by researchers at the University of Georgia. Being overweight is a known risk factor for heart disease, diabetes and a host of other health conditions. Now, obesity and over-weight may also be bad for bone health.

31 Osteoporosis articles listed above.

What is Osteoporosis
The word osteoporosis literally means "porous bones." It occurs when bones lose an excessive amount of their protein and mineral content, particularly calcium. Over time, bone mass, and therefore bone strength, is decreased. As a result, bones become fragile and break easily. Even a sneeze or a sudden movement may be enough to break a bone in someone with severe osteoporosis.

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