Pain



Pain is a universal human experience. The International Association for the Study of Pain (IASP) defines pain as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage." Pain may be a symptom of an underlying disease or disorder, or a disorder in its own right.


Pain - most related articles:

- Sickle cell disease pain occurs daily - 3.9
- TENS device for pain not recommended for chronic low back pain - 3.4
- Ginger consumption eases muscle pain by 25% - 3.4
- Low back pain lumbar supports not reducing sick leave - 3.4
- Exercise more to ease aching back - 3.2
- Swearing can increase pain tolerance - 3.2
- Chronic low back pain treatment can reverse abnormal brain activity - 3.2
- Gene therapy promising for chronic pain relief - 3.2
- Chronic pain increases risk of falls in older adults - 3.2
- Yoga benefits back pain patients - 3.1

Pain articles

Migraine linked to increased risk of depression in women
Women who have migraine or have had them in the past are at an increased risk for developing depression compared to women who have never had migraine. This new study is linking depression in women to migraine in women.

63% women suffer from some knee pain
63% of women age 50 and older reported persistent, incident, or intermittent knee pain during a 12-year study period, revealed by researchers. Predictors for persistent pain included higher body mass index (BMI), previous knee injury, and radiographic osteoarthritis (OA).

Dreaming helps ease bad and painful memories
During the dream phase of sleep, also known as REM sleep, our stress chemistry shuts down and the brain processes emotional experiences and takes the painful edge off difficult memories. Time spent in dream sleep can help.

Pfizer new drug could provide a new treatment option for postmenopausal women
Pfizer Inc. will announce new one-year results from the Selective estrogens, Menopause, And Response to Therapy [SMART]-5 Phase 3 study of the safety and efficacy of the investigational tissue selective estrogen complex (TSEC) bazedoxifene/conjugated estrogens (BZA/CE) at the 22nd annual meeting of the North American Menopause Society (NAMS), September_21-24 in Washington, D.C.

Remicade infliximab approved to treat ulcerative colitis in children
The U.S. Food and Drug Administration approved Remicade (infliximab) to treat moderately to severely active ulcerative colitis (UC) in children older than 6 years who have had inadequate response to conventional therapy.

Massage therapy helps ease chronic low back pain
The hour-long massage treatments (structural and relaxation massage) help people with back pain to function even after six months, reported in a new research. People who have persistent back pain may want to consider massage as an option.

Chronic low back pain treatment can reverse abnormal brain activity
It likely comes as no surprise that low back pain is the most common form of chronic pain among adults. Lesser known is the fact that those with chronic pain also experience cognitive impairments and reduced gray matter in parts of the brain associated with pain processing and the emotional components of pain, like depression and anxiety.

Acetaminophen not more than 325 mg in each dose
The U.S. Food and Drug Administration is asking manufacturers of prescription combination products that contain acetaminophen to limit the amount of acetaminophen to no more than 325 milligrams (mg) in each tablet or capsule.

High dose aspirin reduces pain for severe headache and migraine
An inexpensive, hundred-year-old therapy for pain – aspirin – is effective in high doses for the treatment of severe headache and migraine caused by drug withdrawal, according to a new study by researchers with the UCSF Headache Center.

Acute pain is eased with the touch of a hand
Self touch offers significant relief for acute pain under experimental conditions, revealed by researchers in Current Biology. This is a reason that people naturally clutch their hand after receiving an injury.

Cannabis may offer relief to patients with chronic pain
The medicinal use of cannabis has been debated by clinicians, researchers, legislators and the public at large for many years as an alternative to standard pharmaceutical treatments for pain, which may not always be effective and may have unwanted side effects.

Banana plantain and broccoli fibers could treat Crohn's disease
Crohn's is a condition that affects one in 800 people in the UK and causes chronic intestinal inflammation, leading to pain, bleeding and diarrhoea. Researchers are working with biotechnology company, Provexis, to test a new plantain based food product that could treat patients with the disease.

Primary care doctors get little information about chronic sinusitis
Facial pain. Nasal congestion. Postnasal drip. Fatigue. These are hallmark signs of chronic sinusitis, a swelling of tissue in the nasal and sinus cavity. The illness strikes millions of Americans each year and is one of the top five reasons patients visit their primary care doctor.

Tai Chi may reduce fibromyalgia symptoms
Fibromyalgia sufferers may find relief from the chronic pain condition by doing tai chi, revealed by researchers in the New England Journal of Medicine.

Alcohol may reduce severity of rheumatoid arthritis symptoms
Drinking alcohol may reduce the severity of rheumatoid arthritis according to new research published today. It is the first time that this effect has been shown in humans.

Acupuncture's molecular effects pinned down
Scientists have taken another important step toward understanding just how sticking needles into the body can ease pain. In a paper published online May_30 in Nature Neuroscience, a team at the University of Rochester Medical Center identifies the molecule adenosine as a central player in parlaying some of the effects of acupuncture in the body.

More good cholesterol is not always good for health
We've all heard about the importance of raising HDL, or the so-called "good" cholesterol, and lowering LDL, or "bad" cholesterol, to improve heart health. While we've come to assume HDL cholesterol is an inherently good thing, a new study shows that for a certain group of patients, this is not always the case.

New criteria proposed for diagnosing fibromyalgia
The American College of Rheumatology (ACR) is proposing a new set of diagnostic criteria for fibromyalgia that includes common symptoms such as fatigue, sleep disturbances, and cognitive problems, as well as pain.

Ginger consumption eases muscle pain by 25%
Daily ginger consumption reduces muscle pain caused by exercise, revealed by researchers at the University of Georgia. This is another healthy effect of ginger apart from its use in colds and upset stomachs.

A single dose of aspirin can reduce migraine headache pain
A single dose of 900-1000 mg aspirin can substantially reduce migraine headache pain within two hours, for more than half of people who take it. It also reduces any associated nausea, vomiting, and sensitivity to light or sound (photophobia or phonophobia).

Anticonvulsant medications linked to increased risk of suicide
An analysis of prescription and clinical claims data suggests that the use of certain anticonvulsant medications may be associated with an increased risk of suicide, attempted suicide or violent death, according to a study in the April 14 issue of JAMA.

Botulinum injection may prevent migraine pain
A preliminary study suggests the same type of botulinum injection used for cosmetic purposes may be associated with reduced frequency of migraine headaches that are described as crushing, vicelike or eye-popping (ocular), but not pain that is experienced as a buildup of pressure inside the head.

Pain drugs do not appear to be associated with skin cancer risk
Contrary to previous hypotheses, the use of non-steroidal anti-inflammatory drugs does not appear associated with risk of squamous cell skin cancer, revealed by researchers.

Symptoms have little value to diagnose ovarian cancer earlier
Use of symptoms to trigger a medical evaluation for ovarian cancer does not appear to detect early-stage ovarian cancer earlier and would likely result in diagnosis in only 1 out of 100 women in the general population with such symptoms, revealed in an article.

Two new genes identified causing ankylosing spondylitis
Work done in part by researchers at The University of Texas Health Science Center at Houston has led to the discovery of two new genes that are implicated in ankylosing spondylitis (AS), an inflammatory and potentially disabling disease.

Abuse in childhood may lead to migraine
Researchers from the American Headache Society's Women's Issues Section Research Consortium found that incidence of childhood maltreatment, especially emotional abuse and neglect, are prevalent in migraine patients.

TENS device for pain not recommended for chronic low back pain
The transcutaneous electric nerve stimulation (TENS), a widely used pain therapy involving a portable device, is not recommended to treat chronic low-back pain -- pain that has persisted for three months or longer -- because research shows it is not effective.

Oxygen appears effective in treating cluster headache
Patients with a cluster headache, which is characterized by bouts of excruciating pain usually near the eye or temple, were more likely to report being pain-free within 15 minutes of treatment with high-flow oxygen than patients who received a placebo treatment.

Chronic pain increases risk of falls in older adults
A new study finds that pain may be more hazardous than previously thought, contributing to an increased risk of falls in adults over age 70. Chronic pain is experienced by as many as two out of three older adults.

Pain relief drugs may encourage cancer growth
Opiate-based painkillers like morphine can stimulate the growth and spread of cancer cells, revealed by researchers.

Patients with acute lower back pain can be diagnosed by PCP
Primary care physicians are front line defense in diagnosing serious illness in patients with acute lower back pain, revealed by researchers at The George Institute for International Health in Australia.

Shoe choice may cause foot pain
Women who make poor shoe choices early in life suffer with foot pain in later years, revealed by researchers. The new study is published in the October issue of Arthritis Care & Research, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology.

4 new risk factors for prostate cancer - deCODE genetics
deCODE genetics (Nasdaq:DCGN) announced that a team of its scientists and academic colleagues from Finland, Spain, the Netherlands and the United States have published the discovery of four novel single-letter variations in the sequence of the human genome (SNPs) conferring increased risk of prostate cancer.

Yoga benefits back pain patients
People with chronic low back problems who do yoga also do better at overcoming pain and depression than people treated conventionally for back pain, a West Virginia University study funded by the National Institutes of Health shows.

Strong thigh muscles protect women from osteoarthritis symptoms
Thigh muscle strength does not predict the occurrence of knee osteoarthritis (OA) uncovered in x-rays, but does predict incidence of painful or stiff knee OA, revealed by researchers at the University of Iowa Hospitals and Clinics.

Microneedle patch would replace injections and needles
An array of microneedles could be coated with medicine and act as a painless drug delivery system for flu vaccines, diseases of the eye and more, revealed by researchers.

Swearing can increase pain tolerance
Researchers from Keele University's School of Psychology have determined that swearing can have a 'pain-lessening effect,' according to new study published in NeuroReport, published by Lippincott Williams & Wilkins.

Improving heart attack treatment of patients
When faced with patients suffering a heart attack, doctors have two choices. One is to inject them with medication to dissolve the blood clot, that is fibrinolytic therapy, and second is to insert a small balloon to open the blocked artery i.e. primary percutaneous coronary intervention (PCI).

ABCG2 gene mutation causes gout
Johns Hopkins scientists out a gene for gout - ABCG2 gene mutation is responsible for causing the joint inflammation and pain that are symptoms of gout.

Red yeast rice reduce cholesterol in statin intolerant
Red yeast rice capsules reduce cholesterol LDL (low density lipoprotein) levels in statin intolerant patients without causing any adverse events such as muscle pain and weakness, revealed by researchers.

Lipoprotein a increases heart attack risk
A genetic analysis of data from three studies suggests that genetically elevated levels of lipoprotein(a) are associated with an increased risk of heart attack, according to a study in the June 10 issue of JAMA.

Computer related injuries on rise in young children
While back pain, blurred vision and mouse-related injuries are now well-documented hazards of long-term computer use, the number of acute injuries connected to computers is rising rapidly.

Fatigue common after myocardial infarction heart attack
Half of all patients who undergo myocardial infarction are experiencing onerous fatigue four months after the infarction. The patients who are most fatigued are those who perceive the infarction as a sign of chronic illness, those who experience the illness as difficult to control, and those who believe that the illness has a large impact on their life.

Exercise more to ease aching back
A University of Alberta study of 240 men and women with chronic lower-back pain showed that those who exercised four days a week had a better quality of life, 28 per cent less pain and 36 per cent less disability, while those who hit the gym only two or three days a week did not show the same level of change.

Intervention helps reduce pain and depression
For patients who experience pain and depression, common co-existing conditions, an intervention that included individually tailored antidepressant therapy and a pain self-management program resulted in greater improvement in the symptoms of these conditions than patients who received usual care, according to a study in the May 27 issue of JAMA.

Women with chest pain get no proper treatment from paramedics
Women with chest pain are less likely than male patients to receive recommended, proven therapies while en route to the hospital, according to new research from the University of Pennsylvania School of Medicine.

Children's face paint associated with adverse events
The Food and Drug Administration is advising consumers to stop using certain cosmetic "Face Paint" items labeled as distributed by Oriental Trading Co., Omaha, Neb., due to adverse event reports of skin reactions in children. These items were distributed nationwide.

Acupuncture eases chronic low back pain in SPINE trial
Acupuncture can help people with chronic low back pain feel less bothered by their symptoms and function better in their daily activities, according to the largest randomized trial of its kind, published in the May 11, 2009 Archives of Internal Medicine.

Humans driving increased dengue risk in Australia
Drought-proofing Australia's urban regions by installing large domestic water tanks may enable the dengue mosquito Aedes aegypti to regain its foothold across the country and expand its range of possible infections, according to a new study published May 5 in the open-access journal PLoS Neglected Tropical Diseases.

Infant pain response depends on order of administration of vaccine
Infants who receive the pneumococcal conjugate vaccine (PCV) following the combination vaccine for diphtheria, polio, tetanus, pertussis and Haemophilus influenzae type b (DPTaP-Hib vaccine) appear to experience less pain than those who are immunized in the opposite order, according to a report in the May issue of Archives of Pediatrics & Adolescent Medicine, a theme issue on vaccines.

Electronic device for quick glucose test to aid diabetics
A skin patch could one day provide a less-invasive alternative for diabetics who need to take regular samples of their own blood to keep glucose levels in check. The common method of drawing blood from fingertips and using glucose testing strips and metres can be painful, inconvenient and time-consuming.

Stop oral salicylate gels in under 16s
The Medicines and Healthcare products Regulatory Agency (MHRA) is issuing precautionary advice not to use topical oral pain relief gels containing salicylate salts.

Pain relievers seem not to prevent Alzheimer's disease
A new study shows that nonsteroidal anti-inflammatory drugs (NSAIDs) such as the pain relievers ibuprofen and naproxen do not prevent Alzheimer's disease, but they may instead delay its onset.

Migraine patients can exercise now
Many patients who suffer from migraines avoid taking aerobic exercise because they are afraid that the physical activity may bring on a serious migraine attack.

Fir tree found in man's lung
A 5 cm fir tree has been found in the lung tissue of a 28 year old russian man who complained of pain in his chest.

Back pain diagnosis easier with simple bedside test
A simple and inexpensive method of assessing pain, developed by Massachusetts General Hospital (MGH) researchers, is better than currently used techniques for distinguishing neuropathic pain – pain caused by damage to the nervous system – from other types of chronic back pain.

10 genes identified in connection with sudden cardiac death
Irregular heart rhythms are a common cause of sudden cardiac death or SCD, a condition that accounts for 450,000 deaths annually in the United States.

Vitamin C lowers gout risk in men
Men with higher vitamin C intake appear less likely to develop gout, a painful type of arthritis, according to a report in the March 9 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Herpes zoster or shingles risk more with rheumatoid arthritis medicines
Use of certain medications known as monoclonal anti tumor necrosis factor a (TNF-a) antibodies for the treatment of rheumatoid arthritis appears to be associated with an increased risk for herpes zoster (shingles), the painful infection characterized by blisters, according to a study in the February 18 issue of JAMA.

Routine scans for low back pain do not improve outcomes
Physicians should not immediately order routine scans for low-back pain unless they observe features of a serious underlying condition, researchers in the Oregon Evidence-Based Practice Center at Oregon Health & Science University report.

Milnacipran for management of fibromyalgia approved
Pierre Fabre Laboratories announced that the Food and Drug Administration (FDA) has just approved the marketing application filed by Forest Laboratories, Inc. and Cypress Bioscience, Inc. for Milnacipran.

FDA will review Daiichi Sankyo, Lilly drug Prasugrel for heart attack
Daiichi Sankyo Company, Limited (TSE: 4568) and Eli Lilly and Company (NYSE: LLY) confirmed that the U.S. Food and Drug Administration's (FDA) Cardiovascular and Renal Drugs Advisory Committee (CRDAC) will review prasugrel during an advisory committee hearing on February_3, 2009.

Back pain is reoccurring problem for Australians
A new study by researchers at The George Institute for International Health has found that back pain is a reoccurring problem for five million Australians.

Water aerobics in pregnancy help pregnant women during labor
A course of water aerobics classes has been shown to reduce the amount of pain-killing medication women request during labor.

Chinese exercise Tai chi relieves knee pain
Tai chi is effective in the treatment of pain and physical impairment in people with severe knee osteoarthritis, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in San Francisco, Calif.

Palliative care access varies widely in US
There has been rapid growth of new, innovative palliative care consultation services in the US's hospitals. More than half of the 50-bed or larger hospitals in the U.S. offer palliative care services to ease pain and suffering for seriously ill patients and their families.

New genes linked to gout
Researchers have identified two new genes – and confirmed the role of a third gene – associated with increased risk of higher levels of uric acid in the blood, which can lead to gout, a common, painful form of arthritis.

Pain is not a symptom of arthritis, pain causes arthritis
Pain is more than a symptom of osteoarthritis, it is an inherent and damaging part of the disease itself, according to a study published today in journal Arthritis and Rheumatism.

Arthroscopy may not help osteoarthritis patients
Arthroscopic surgery for osteoarthritis of the knee provides no additional benefit to optimized physical and medical therapy, revealed by researchers in a study published in the New England Journal of Medicine (NEJM) issue of Sept. 11, 2008.

Alexander technique offers long-term relief for back pain
Alexander technique lessons in combination with an exercise programme offer long-term effective treatment for chronic back pain, according to a study published on BMJ.com.

Paint chemicals may harm sperms, male fertility
A new study has revealed that chemicals used in paint emulsions may damage semen quality in males, making them infertile. The results of the study have been published in the 'Occupational Environmental Medicine' journal.

Women more likely to ignore heart attack warnings
Many women under age 55 aren't seeking timely treatment for heart attack because they expect the warning signs and their reaction to follow a Hollywood script - tightening in the chest, shortness of breath, clutching the chest while dropping to one knee.

Low back pain lumbar supports not reducing sick leave
Lumbar or lower back supports - those large belts that people wear around their waists when they lift or carry heavy objects - are not very useful for preventing low back pain, according to a new systematic review.

Preterm babies could benefit from skin-to-skin cuddling
Preterm babies, born between 28 and 31 weeks, could benefit from skin-to-skin cuddling with their mother before and during painful procedures such as a heel lance, reported in a recent study.

Women's labour experiences differ from expectations
A pain-free and drug-free labour may be many expectant mothers' dream but a review in the open access journal BMC Medicine reveals that reality hits hard. Most women's labour experiences differ markedly from their expectations. They are often ill-prepared for what might happen and consequently may be disappointed when the birth does not "go to plan".

Knee surgery referral to men more
Physicians and surgeons recommend knee replacement surgery to men more than female patients complaining of knee pain, revealed by canadian researchers highlighting unconscious prejudices among doctors.

Aromatherapy makes you feel good only
Aromatherapy failed to show any improvement in either immune status, wound healing or pain control among people exposed to two often-touted scents, revealed by researchers in a recent study.

Safer effective way to treat Crohn's disease
A new study established the new alternative strategy, called "top-down" therapy, to treat the patients with Crohn's disease by employing early use of immune-suppressing drugs combined with an antibody without using steroids.

Aquatic exercise could benefit fibromyalgia sufferers
Patients suffering from fibromyalgia could benefit significantly from regular exercise in a heated swimming pool, a study published today in the open access journal Arthritis Research & Therapy shows. The findings suggest a cost effective way of improving quality of life for patients with this often-debilitating disorder.

Glucosamine no better than placebo in reducing hip pain
A new, two-year, randomized, placebo-controlled trial found that glucosamine sulfate was no better than placebo in controlling hip pain, the ability to do normal activities and the progression of hip osteoarthritis. Glucosamine is a natural substance found in healthy joint cartilage.

Duragesic 25 mcg/hr CII pain patches recalled
DURAGESIC 25 mcg/hr (fentanyl transdermal system) CII patches for pain have been recalled because of a cut along one side of the drug reservoir within the patch. Fentanyl patches that are cut or damaged in any way may lead to serious adverse events.

Back pain expenses and disability rising
Although expenses related to back and neck problems have increased substantially in the last decade in US, outcomes such as functional disability and work limitations do not appear to be improving, revealed by researchers.

Gain control of your heart health
Dr. Charlotte Bai, a noted cardiologist with special expertise in cardiac imaging, has a special message for people with risk factors for heart disease: What you don't know can hurt you. "February is National Heart Month. And now is a great time to gain control of your heart health," said Bai, assistant professor, cardiology, Department of Medicine, Loyola University Stritch School of Medicine.

Sugary soft drinks linked to gout in men
Consumption of sugar sweetened soft drinks and fructose is strongly associated with an increased risk of gout in men. Gout is a joint disease which causes extreme pain and swelling. It is most common in men aged 40 and older. It is caused by excess uric acid in the blood (hyperuricaemia) which leads to uric acid crystals collecting around the joints.

Gene therapy promising for chronic pain relief
Now, chronic pain can be successfully treated with novel targeted gene therapy. In an effort to find a more effective treatment for chronic pain, researchers at Mount Sinai developed a gene therapy technique that simulates the pain-killing effect of opiate drugs.

Sickle cell disease pain occurs daily
Sickle cell disease pain can occur daily, and is far more prevalent and severe than previous large studies have indicated. Patients are at home mostly struggling with their pain rather than coming into the hospital or emergency department.

Osteoporosis drugs increase bone necrosis risk
A popular class of osteoporosis drugs, bisphosphonates nearly triples the risk of developing bone necrosis, a condition that can lead to disfigurement and incapacitating pain, revealed by researchers in a study. The research conducted by reasearchers at the University of British Columbia and Vancouver Coastal Health Research Institute, Canada.

Arthritis drug celecoxib can adversely affect heart rhythm
COX-2 inhibitors like Celecoxib have come under scrutiny lately due to adverse cardiovascular side-effects stemming from COX-2 reduction. In both fruit fly and rat models, researchers reveal another adverse effect of Celecoxib; this drug can induce arrhythmia. More interestingly, this effect is independent of the COX-2 enzyme.

Weight loss caused by chewing gum - BMJ
Severe weight loss was detected in patients due to chronic diarrhea after eating chewing gum and sweets because of excess sorbitol intake, a widely used sweetener in "sugar-free" products. Sorbitol has laxative properties and is poorly absorbed by the small intestine.

Don't postpone knee-replacement surgery
Research at the University of Delaware indicates that women wait longer to pursue knee-replacement surgery than men do.

Exercise improves symptoms in arthritis patients
Patients with arthritis tend to be less fit than their peers who don't have this condition. Studies have shown, however, that they can safely participate in exercise programs to increase their fitness, strength and psychosocial status and that health providers recommend that arthritis patients participate in exercise.

Safety warning on fentanyl skin patch by US FDA
The US Food and Drug Administration issued its second safety warning about the fentanyl transdermal system, an adhesive patch that delivers a potent pain medicine through the skin. In July 2005, the agency issued a similar warning to the public and to health care providers, saying that the directions on the product label and on the patient package insert should be followed exactly in order to avoid overdose.

Chest pain - common sign of heart attack for women
Chest pain or discomfort has long been regarded as the most common early warning sign of a heart attack for both men and women. However, several recent reports have found that women are more likely to have other symptoms of a heart attack. A new study looked at the available evidence and concluded that chest pain is the most common sign of heart attack for most women.

Massage eases pain and anxiety after surgery
A 20-minute evening back massage may help relieve pain and reduce anxiety following major surgery when given in addition to pain medications, according to a report in the December issue of Archives of Surgery, one of the JAMA/Archives journals.

Cows milk may cause Crohn's disease
Researchers at the University of Liverpool have found how a bacterium, known to cause illness in cattle, may cause Crohn's disease in humans. Crohn's is a condition that affects one in 800 people in the UK and causes chronic intestinal inflammation, leading to pain, bleeding and diarrhoea.

95 Pain articles listed above.


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What is Pain
Pain is a universal human experience. The International Association for the Study of Pain (IASP) defines pain as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage." Pain may be a symptom of an underlying disease or disorder, or a disorder in its own right.



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