Pharmacology
Avoid grapefruit juices when taking certain drugsGrapefruit and other common fruit juices, including orange and apple, decrease the absorption of drugs, potentially wiping out their beneficial effects.
Cold sore's herpes simplex virus mechanism revealedNow that Duke University Medical Center scientists have figured out how the virus that causes cold sores hides out, they may have a way to wake it up and kill it.
New bird flu vaccine may give long-term defenseA new vaccine under development may provide protection against highly pathogenic bird flu and its evolving forms, according to researchers at Purdue University and the Centers for Disease Control and Prevention who discovered the new preventative drug and have tested it in mice.
Gene identified for hair loss in hypotrichosis simplexA healthy individual loses around a hundred hairs a day. Nothing to worry about as long as they are constantly replaced and the losses occur evenly around the whole scalp. But when hair loss goes well beyond this level it can become quite a problem for those affected – not only superficially in terms of looks but also psychologically.
Safer effective way to treat Crohn's diseaseA new study established the new alternative strategy, called "top-down" therapy, to treat the patients with Crohn's disease by employing early use of immune-suppressing drugs combined with an antibody without using steroids.
Overweight pregnant women may have fatter childrenMothers-to-be beware. Women who are overweight during pregnancy may be more likely to have fatter children susceptible to chronic health problems, University of New South Wales (UNSW) research shows.
Polycarbonate plastic bottles harmful for hot liquidsLiquid's temperature that has the most impact on how much Bisphenol A (BPA) is released from polycarbonate plastic bottles, and it does not matter whether the container is new or old, revealed by researchers from the University of Cincinnati (UC).
Arthritis drug celecoxib can adversely affect heart rhythmCOX-2 inhibitors like Celecoxib have come under scrutiny lately due to adverse cardiovascular side-effects stemming from COX-2 reduction. In both fruit fly and rat models, researchers reveal another adverse effect of Celecoxib; this drug can induce arrhythmia. More interestingly, this effect is independent of the COX-2 enzyme.
Lung cancer cells' survival gene 14-3-3zeta seen as drug targetOne of the deadliest forms of cancer appears to carry a specific weakness. When a key gene called 14-3-3zeta is silenced, lung cancer cells can't survive on their own, researchers have found.
Gene changes may lead to hardening of arteries, atherosclerosisResearchers revealed that changes in gene may lead to hardening of the arteries and expands lesions in the aorta and promotes coronary atherosclerosis. The study was done by researchers from Yale School of Medicine and published in Cell Metabolism.