Prostate Cancer

Prostate cancer is a malignancy of one of the major male sex glands, in which cells of the prostate become abnormal and start to grow uncontrollably, forming tumors.

Prostate Cancer - most related articles:

- Prostate cancer risk from heavy drinking - 6
- High insulin level increases prostate cancer risk - 5.9
- Smoking may increase risk of prostate cancer recurrence - 5.7
- Prostate biopsy is not always necessary after raised PSA levels - 5.7
- Men with wives more likely to be screened for prostate cancer - 5.7
- Prostate cancer family history has no impact on treatment - 5.7
- STD increases prostate cancer risk - 5.6
- Brothers of prostate cancer patients undergo more diagnostic activities - 5.5
- Advanced stage prostate cancer patients experience 20 year survival rates with surgery - 5.4
- Prostate cancer screening for men over 75 not required - 5.3

Prostate Cancer articles

Cancer screening in older adults appears common, US
A high percentage of adults age 75 years and older continue to report receiving cancer screenings, despite U.S. Preventive Services Task Force guidelines recommending against routine screening for breast, cervical, colorectal and prostate cancer for patients age 75 years and older.

35 new drugs approved in 2011 in US
Over the past 12 months, the U.S. Food and Drug Administration approved 35 new medicines for patients, like two new treatments for hepatitis C; a drug for late-stage prostate cancer; the first new drug for Hodgkin's lymphoma in 30 years; and the first new drug for lupus in 50 years.

PSA test helps predicting biopsy need and low risk prostate cancer
The prostate-specific antigen test, commonly known as the PSA test, is valuable in predicting which men should have biopsies and which are likely to be diagnosed with low-risk prostate cancer, a Mayo Clinic study has found. The findings were released during a meeting of the North Central Section of the American Urological Association in Rancho Mirage, California, US.

More aggressive treatment not necessary for men with a family history of prostate cancer
Approximately 10-20 percent of prostate cancer patients have a family history of the disease. There are three major factors that are used to evaluate the extent and aggressiveness of prostate cancer, help make treatment decisions, and estimate prognosis: the Prostate Specific Antigen Level (PSA), Gleason score (GS) from the biopsy, and the digital rectal exam findings (DRE).

Alpharadin improved survival in advanced prostate cancer patients
Until recently, options for patients with bone metastases from advanced prostate cancer have been very limited. But now the first Phase III study of an alpha-pharmaceutical in these patients has shown that it can prolong survival significantly, according to research reported recently at the 2011 European Multidisciplinary Cancer Congress.

5 inherited genetic variants linked to prostate cancer
An international team of researchers led by Fred Hutchinson Cancer Research Center has identified five inherited genetic variants that are strongly associated with aggressive, lethal prostate cancer.

New urine test can detect prostate cancer risk early
A new urine test can help aid early detection of and treatment decisions about prostate cancer. Examining the urine sample for TMPRSS2:ERG and PCA3 and stratified patient into low, intermediate and high score, indicating their risk of cancer can help.

Encouraging men to seek evidence based information of prostate cancer
Encouraging men to seek up-to-date evidenced-based information from their GPs about screening and treatment of prostate cancer disease and screening for prostate cancer is recommended. The Royal New Zealand College of General Practitioners (RNZCGP) has welcomed the release of the results of the Health Select Committee's inquiry into the early detection and treatment of prostate cancer.

Smoking may increase risk of prostate cancer recurrence
Researchers found that men with prostate cancer who were current smokers had a 61% increased risk of dying from prostate cancer, and a 61% higher risk of recurrence compared with men who never smoked. This new study from Harvard School of Public Health (HSPH) and University of California, San Francisco, researchers suggests that men with prostate cancer who smoke increase their risk of prostate cancer recurrence and of dying from the disease.

Brisk walking could improve prostate cancer outcomes
Men with prostate cancer can improve their outcomes if they walk briskly for at least three hours a week following their diagnosis, according to a recent study in Cancer Research, a journal of the American Association for Cancer Research.

Coffee may reduce prostate cancer risk
It is a good news for men who regularly drink coffee. They appear to have a lower risk of developing a lethal form of prostate cancer, revealed by researchers from Harvard School of Public Health (HSPH) US.

Obese men face higher risk of prostate cancer progression
Even when treated with hormone therapy to suppress tumor growth, obese men face an elevated risk of their prostate cancer worsening, researchers at Duke University Medical Center have found.

Advanced stage prostate cancer patients experience 20 year survival rates with surgery
Long-term survival rates for patients with advanced prostate cancer suggest they can be good candidates for surgery, Mayo Clinic researchers have found. Their study found a 20-year survival rate for 80 percent of patients diagnosed with cancer that has potentially spread beyond the prostate, known as cT3 prostate cancer, and treated with radical prostatectomy, or surgery to remove the prostate gland.

Zytiga approved for late stage prostate cancer
The U.S. Food and Drug Administration approved Zytiga (abiraterone acetate) in combination with prednisone (a steroid) to treat patients with late-stage (metastatic) castration-resistant prostate cancer who have received prior docetaxel (chemotherapy).

Omega 3 good for heart not for prostate
The largest study ever to examine the association of dietary fats and prostate cancer risk has found what's good for the heart may not be good for the prostate.

Acupuncture relieves hot flashes from prostate cancer treatment
Acupuncture provides long-lasting relief to hot flashes, heart palpitations and anxiety due to side effects of the hormone given to counteract testosterone, the hormone that induces prostate cancer, according to a study published in the April issue of the International Journal of Radiation Oncology•Biology•Physics, an official journal of the American Society for Radiation Oncology (ASTRO).

Testosterone - prostate cancer link needs reevaluation
The long-standing prohibition against testosterone therapy in men with untreated or low-risk prostate cancer merits reevaluation, according to a new study published in The Journal of Urology.

Closely monitoring better for low risk prostate cancer
A Johns Hopkins study of 769 men from across the United States recently diagnosed with low-grade prostate cancer shows that forgoing immediate surgery to remove the tumor or radiation poses no added risk of death.

Adoption of newer, more expensive prostate cancer treatments
With 180,000 men diagnosed with prostate cancer each year, it is one of the most common types of cancer in US. For this reason, it has been cited as a good marker for health care spending in general, reflective of the greater trends across the United States.

Gene based prostate cancer test may make more accurate treatment decisions
Researchers conducted an elaborate series of experiments to identify the genes most closely linked to the aggressive biology of prostate cancer. They found about 300 genes that distinguished the two groups - indolent versus aggressive prostate cancers.

New drug approach for prostate cancer drug
A small slice of RNA inhibits prostate cancer metastasis by suppressing a surface protein commonly found on prostate cancer stem cells, revealed by researchers.

Incontinence after prostate surgery reduced with behavioral therapy
For men with incontinence for at least one year following radical prostatectomy, participation in a behavioral training program that included pelvic floor muscle training, bladder control strategies and fluid management, resulted in a significant reduction in the number of incontinence episodes.

Age plays too big a role in prostate cancer treatment decisions
Older men with high-risk prostate cancer frequently are offered fewer – and less effective – choices of treatment than younger men, potentially resulting in earlier deaths, according to a new UCSF study.

Potential target identified for therapy for prostate cancer
A monoclonal antibody targeting a well known cell surface protein inhibited prostate cancer growth and metastasis in an aggressive form of the disease that did not respond to hormone therapy.

Prostate cancer care cost varies with initial treatment choice
A new analysis has found that short-term and long-term costs of prostate cancer care vary considerably based on which treatment strategy a man initially receives.

Brothers of prostate cancer patients undergo more diagnostic activities
The brothers of men with prostate cancer are at an increased risk of prostate cancer diagnosis because of increased diagnostic activity and not necessarily because they carry a genetic mutation that increases risk of the disease, according to a study published online August 19 in The Journal of the National Cancer Institute.

Dense bones linked to prostate cancer risk
Men who develop prostate cancer, especially the more aggressive and dangerous forms that spread throughout the body, tend to retain denser bones as they age than men who stay free of the disease, suggests new research from Johns Hopkins and the National Institute on Aging (NIA), part of the National Institutes of Health.

Cancer deaths continue to drop in US
The continued drop in overall cancer mortality rates over the last 20 years has averted more than three-quarters of a million (767,000) cancer deaths according to a new report from the American Cancer Society.

Statins lower prostate cancer recurrence after prostatectomy
Men who use statins to lower their cholesterol are 30 percent less likely to see their prostate cancer come back after surgery compared to men who do not use the drugs, according to researchers at Duke University Medical Center. Researchers also found that higher doses of the drugs were associated with lower risk of recurrence.

New PSA test predicts if prostate cancer will return
New research from Northwestern University Feinberg School of Medicine and the University International Institute for Nanotechnology shows that an ultrasensitive PSA test using nanoparticle-based technology (VeriSens™ PSA, Nanosphere, Inc., research-use-only) may be able to definitively predict after surgery if the cancer is cured long term or if it will recur.

Refusal to prostate cancer surgery may impact survival
Men who refuse surgery for prostate cancer and instead opt for "watchful waiting" – monitoring cancer progression without undergoing treatment – have a significantly worse long-term survival rate than those patients that choose radiotherapy, according to researchers at Henry Ford Hospital in Detroit.

Exercise may keep cancer patients healthier
Breast and prostate cancer patients who regularly exercise during and after cancer treatment report having a better quality of life and being less fatigued, according to researchers at Henry Ford Hospital in Detroit.

Dutasteride reduces prostate cancer risk in high risk men
Dutasteride (Avodart) - a drug already prescribed to shrink benign, enlarged prostates has been shown to reduce the risk of a prostate cancer diagnosis by 23 percent in men.

Walnuts may help fight prostate cancer
Scientists in California are reporting for the first time that walnuts - already renowned as a rich source of omega-3 fatty acids that fight heart disease - reduce the size and growth rate of prostate cancer in test animals.

Infertility increases prostate cancer risk in men
Infertile men have an increased risk of developing high grade prostate cancer, which is more likely to grow and spread quickly. That is the conclusion of a new study published early online in Cancer.

Noscapine may reduce tumor growth in prostate cancer patients
Noscapine, cough medicine ingredient, can be used as a prophylactic treatment for prostate cancer. The new study shows that noscapine inhibited tumor growth in mice and also limited the spread of tumors without causing any side effects.

Dietary supplements discouraged for prostate cancer patients
Prostate-specific dietary supplements should not be taken during radiation therapy treatments because they have been shown to increase the radiosensitivity of normal prostate cell lines, leading to normal tissue complications.

New tool illuminates connections between stem cells and cancer
Researchers have a new tool to understand how cancers grow -- and with it a new opportunity to identify novel cancer drugs. They've been able to break apart human prostate tissue, extract the stem cells in that tissue, and alter those cells genetically so that they spur cancer.

Gene linked to aggressive form of prostate cancer
Researchers at Wake Forest University Baptist Medical Center and colleagues have identified the first genetic variant associated with aggressive prostate cancer, proving the concept that genetic information may one day be used in combination with other factors to guide treatment decisions.

Hops compound xanthohumol may prevent prostate cancer
The natural compound xanthohumol blocks the effects of the male hormone testosterone, therefore aiding in the prevention of prostate cancer, revealed by US researchers.

Prostate biopsy is not always necessary after raised PSA levels
Elevated prostate specific antigen (PSA) levels in men may be caused by a hormone normally occurring in the body, and are not necessarily a predictor of the need for a prostate biopsy, revealed by researchers.

Prostate cancer test age lowered to 40
The age at which men are recommended to first have a test to help identify prostate cancer has been reduced from 50 to 40 years of age.

4 new risk factors for prostate cancer - deCODE genetics
deCODE genetics (Nasdaq:DCGN) announced that a team of its scientists and academic colleagues from Finland, Spain, the Netherlands and the United States have published the discovery of four novel single-letter variations in the sequence of the human genome (SNPs) conferring increased risk of prostate cancer.

STD increases prostate cancer risk
Researchers confirmed previous findings that the sexual transmitted infection known as Trichomonas vaginalis is associated with an increased risk of prostate cancer in a study published online September 9 in the Journal of the National Cancer Institute.

XMRV virus may cause prostate cancer in people
XMRV (Xenotropic murine leukemia virus-related virus) -- a type of virus known to cause leukemia and sarcomas in animals has been found for the first time in malignant human prostate cancer cells.

High insulin level increases prostate cancer risk
Elevated insulin levels in the normal range appear to be associated with an increased risk of prostate cancer, revealed by researchers in a new study published in the Journal of the National Cancer Institute.

Prostatectomy effective in men with aggressive prostate cancer
Prostate surgery prostatectomy is found very effective in preventing death in men with aggressive prostate cancers, revealed by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC), Cleveland Clinic and the University of Michigan.

Prostate cancer risk from heavy drinking
In a new study, researchers examined the associations of total alcohol, type of alcoholic beverage, and drinking pattern with risks of total, low- and high-grade prostate cancer.

Prostate cancer screening may result in overdiagnosis of cancer
The recent release of two large randomized trials suggests that if there is a benefit of screening, it is, at best, small, says a new report in CA: A Cancer Journal for Clinicians.

Selenium may worsen prostate cancer in some
Higher selenium levels in the blood may worsen prostate cancer in some men who already have the disease, revealed by researchers.

Success with ipilimumab in prostate cancer patients
Two Mayo Clinic patients whose prostate cancer had been considered inoperable are now cancer free thanks in part to an experimental drug therapy that was used in combination with standardized hormone treatment and radiation therapy.

Green tea slows prostate cancer progression
Men with prostate cancer who consumed the active compounds in green tea demonstrated a significant reduction in serum markers predictive of prostate cancer progression, revealed by researchers.

Prostate cancer impacts quality of life of patient
A long-term study by researchers at UCLA's Jonsson Comprehensive Cancer Center found that the three most common treatments for localized prostate cancer had significant impacts on patients' quality of life, a finding that could help guide doctors and patients in making treatment decisions.

Carbohydrate restriction may slow prostate tumor growth
Restricting carbohydrates, regardless of weight loss, appears to slow the growth of prostate tumors, according to an animal study being published this week by researchers in the Duke Prostate Center.

3 minute quick test for prostate cancer
A new 3-minute test could help in diagnosing prostate cancer, the most common cancer in men in the UK, according to scientists. Researchers have developed the test by using light energy to measure the level of citrate in fluid samples from the prostate gland.

Genetic marker predicts early onset of prostate cancer
Fox Chase Cancer Center researchers have identified a genetic marker that is associated with an earlier onset of prostate cancer in Caucasian men who have a family history of prostate cancer. If the data are confirmed, the marker may help clinicians personalize prostate cancer screening.

Prostate surgery improves younger prostate cancer patients survival
For men younger than 50 with prostate cancer, undergoing a radical prostatectomy can greatly increase their chances for long-term survival, according to a new study from Henry Ford Hospital.

Prostate cancer immunotherapy prolongs survival
Sipuleucel-T (Provenge), an experimental immunotherapy improved survival in men with metastatic disease, according to new results to be presented April 28 at the American Urological Association (AUA) Annual Scientific Meeting in Chicago.

Men should get PSA testing at age 40
The American Urological Association (AUA) issued new clinical guidance – which directly contrasts recent recommendations issued by other major groups – about prostate cancer screening, asserting that the prostate-specific antigen (PSA) test should be offered to well-informed, men aged 40 years or older who have a life expectancy of at least 10 years.

Statins reduce inflammation in prostate tumors
Cholesterol lowering drugs called statins may reduce inflammation in prostate tumors, possibly hindering cancer growth, according to a study led by investigators in the Duke Prostate Center.

Nanotechnology offers new cancer breakthrough hope
A multi-disciplinary team of scientists from the University of Leicester could be potentially paving the way for the development of a powerful new strategy for both the early diagnosis and treatment of prostate cancer.

Prostate cancer vaccine Provenge prolongs survival
Dendreon Corporation (Nasdaq: DNDN) announced that the pivotal Phase 3 IMPACT study of PROVENGE (sipuleucel-T) in men with advanced prostate cancer met its primary endpoint of improving overall survival compared to a placebo control.

Omega 3 reduces prostate cancer risk
Omega-3 fatty acids appear protective against advanced prostate cancer, and this effect may be modified by a genetic variant in the COX-2 gene, according to a report in Clinical Cancer Research, a journal of the American Association for Cancer Research.

Heavier alcohol use predicts prostate cancer
An international research team from Australia, Canada and the United States found that men who drank two or more standard drinks of alcohol a day are more likely to develop prostate cancer.

Prostate cancer family history has no impact on treatment
Family history of prostate cancer does not affect some prostate cancer patient's treatment outcomes, revealed by researchers.

Grape seed extract may cure leukemia
An extract from grape seeds forces laboratory leukemia cells to commit cell suicide, according to researchers from the University of Kentucky. They found that within 24 hours, 76 percent of leukemia cells had died after being exposed to the extract.

Income linked to prostate cancer grade
Low-income men are more likely to present with advanced prostate cancers, most likely because they don't receive screening services shown to reduce the diagnosis of later-stage cancers, a UCLA study found.

Men with wives more likely to be screened for prostate cancer
Although the link between early screening and prostate cancer survival is well established, men are less likely to go for early screening unless they have a wife or significant other living with them, according to a study published in Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research.

PSA screening awareness needed among high-risk groups
In one of the first examinations of PSA screening in younger men, a study published by researchers at Duke Medicine's Prostate Center finds that one-fifth of men under age 50 reported undergoing a prostate specific antigen (PSA) test to detect prostate cancer in the previous year, yet only one in three young black men reported ever having a PSA test in the previous year.

Prostate cancer screening for men over 75 not required
The U.S. Preventive Services Task Force (USPSTF), updating its 2002 report, now recommends against routine prostate cancer screening for men over the age of 75. More evidence is needed to determine if men under 75 could benefit from screening.

Broccoli rich diet prevents prostate cancer
For the first time, a UK research group at the Institute of Food Research led by Professor Richard Mithen has provided an explanation of how eating broccoli might reduce cancer risk based upon studies in men, as opposed to trying to extrapolate from animal models.

Type 2 diabetes genes associated with prostate cancer
Scientists have identified six new genes which play a role in the development of type 2 diabetes, and among the group is the second gene known to also play a role in prostate cancer.

21% errors in pathology reports in Miramichi Hospital, New Brunswick
An additional review of pathology reports in Miramichi Hospital, New Brunswick is completed by Dr. Rosemary Henderson, pathologist. This review included 227 cases of prostate and breast cancer biopsies from 2004-2005. The results indicated that 18 percent of the cases had incomplete results and three percent of the cases were misdiagnosed.

7 new prostate cancer genetic risk factors identified
7 new sites in the human genome identified that are linked to men's risk of developing prostate cancer, revealed by Cancer Research UK funded scientists at the Institute of Cancer Research and University of Cambridge.

$9 million grant for prostate cancer research
Henry Ford Hospital is embarking on an expanded major clinical trial involving the use of gene therapy in combination with radiation therapy, to determine if the combined treatment is more effective than radiation therapy alone for patients with intermediate risk prostate cancer.

Simple urine test detecting prostate cancer accurately
An experimental biomarker test developed by researchers at the University of Michigan more accurately detects prostate cancer than any other screening method currently in use, according to a study published in the February 1 issue of Cancer Research, a journal of the American Association for Cancer Research.

1000 Genomes Project to support disease studies
An international research consortium announced the 1000 Genomes Project, an ambitious effort that will involve sequencing the genomes of at least a thousand people from around the world to create the most detailed and medically useful picture to date of human genetic variation.

GVAX cancer immunotherapy improves prostate cancer survival
Cell Genesys, Inc. (Nasdaq: CEGE) announced that the Independent Data Monitoring Committee (IDMC) for VITAL-1, the first of two ongoing Phase 3 clinical trials of GVAX immunotherapy for prostate cancer, has completed a pre-planned interim analysis and has recommended that the study continue, as GVAX cancer immunotherapy improves prostate cancer patients survival.

Genetic testing can gauge prostate cancer risk
Genetic testing of DNA in a blood sample can determine which men are likely to develop prostate cancer, as five genetic variants previously associated with prostate cancer risk have a strong cumulative effect.

Night shift work may cause cancer
A study by the World Health Organization has found that night shift work increases the risk of cancer in humans. The study found that after prolonged exposure to night shift work, women are at a higher risk to develop breast and colon cancer. Men who work the night shift are more likely to experience prostate cancer.

80 Prostate Cancer articles listed above.

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What is Prostate Cancer
Prostate cancer is a malignancy of one of the major male sex glands, in which cells of the prostate become abnormal and start to grow uncontrollably, forming tumors.

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