Rectal Cancer
Cancer of the rectum is the disease characterized by the development of malignant cells in the lining or epithelium of the rectum. Malignant cells have changed such that they lose normal control mechanisms governing growth. These cells may invade surrounding local tissue or they may spread throughout the body and invade other organ systems.
Rectal Cancer - most related articles:
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Rectal cancer rates rising in young individuals in US - 8.2
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Evaluating risk factors of sporadic colorectal cancer - 3.8
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Asacol found effective in ulcerative colitis, proctitis - 3.6
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More aggressive treatment not necessary for men with a family history of prostate cancer - 3.2
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Prostate cancer test age lowered to 40 - 3.1
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GenWay Biotech distributor of AMDL's DR-70 cancer test in US and Canada - 2.9
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IMRT Radiation optimal for localized prostate cancer - 2.8
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Activation of biomarker may improve survival among obese patients with colorectal cancer - 2.6
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New warning for nonoxynol 9 OTC contraceptives in US - 2.2
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Remicade infliximab approved to treat ulcerative colitis in children - 2.1
Rectal Cancer articles
CT colonography a front line colorectal cancer screening tool for seniorsComputerized tomographic (CT) colonography (CTC), also known as virtual colonoscopy, is comparable to standard colonoscopy in its ability to accurately detect cancer and precancerous polyps in people ages 65 and older.
Regorafenib improves survival of colorectal cancer patientsRegorafenib - an investigational drug - slowed the progression of tumors and lengthened the lives of patients with metastatic colorectal cancer. This is the first novel agent in eight years to show improvement in overall survival of colon cancer patients who have run out of treatment options.
Cancer screening in older adults appears common, USA high percentage of adults age 75 years and older continue to report receiving cancer screenings, despite U.S. Preventive Services Task Force guidelines recommending against routine screening for breast, cervical, colorectal and prostate cancer for patients age 75 years and older.
Breast cancer vaccine reduces tumours in miceResearchers have developed a vaccine that dramatically reduces tumors in a mouse model that mimics 90 percent of human breast and pancreatic cancer cases-including those that are resistant to common treatments.
High fiber diet reduces colorectal cancer riskEating a diet high in fibre, particularly from cereal and whole grains, is associated with a reduced risk of colorectal cancer. Intake of dietary fibre and whole grains is known to help protect against cardiovascular disease, but its association with colorectal cancer risk is less clear. And, although the idea that dietary fibre reduces the risk of colorectal cancer has been around for nearly 40 years.
New class of cancer drugs could work in colon cancers with genetic mutationA class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.
Activation of biomarker may improve survival among obese patients with colorectal cancerAmong obese patients, activation of the protein biomarker CTNNB1 was associated with better colorectal cancer-specific survival and overall survival, whereas post-diagnosis physical activity was associated with better colorectal cancer-specific survival among patients negative for CTNNB1.
Nanomedicine closer to reality, StanfordA class of engineered nanoparticles -- gold-centered spheres smaller than viruses -- has been shown safe when administered by two alternative routes in a mouse study led by investigators at the Stanford University School of Medicine.
New stool test to predict colon cancerAn investigational DNA methylation test could alter the screening landscape for colorectal cancer, according to data presented at the American Association for Cancer Research special conference on Colorectal Cancer: Biology to Therapy, held here Oct. 27-30, 2010.
Obesity in colon cancer patients increases mortalityPostmenopausal women diagnosed with colon cancer may be at increased risk of death if they fail to maintain a healthy body weight before cancer diagnosis, revealed by researchers.
Rectal cancer rates rising in young individuals in USA new analysis has found that while colon cancer rates have remained steady over the past several decades among people under the age of 40, rectal cancer rates are increasing in this population across races and in both sexes.
Cancer deaths continue to drop in USThe continued drop in overall cancer mortality rates over the last 20 years has averted more than three-quarters of a million (767,000) cancer deaths according to a new report from the American Cancer Society.
Omega 3 curbs precancerous growths in those prone to bowel cancerA purified form of an omega 3 cuts the number and size of precancerous bowel growths (polyps) in people whose genetic make-up predisposes them to bowel cancer, finds research published ahead of print in the journal Gut.
FDA declines Fusilev NDA for colorectal cancerA Complete Response letter is issued by the U.S. Food and Drug Administration (FDA) regarding the supplemental New Drug Application (sNDA) for FUSILEV (levoleucovorin) for injection for treatment of patients with advanced metastatic colorectal cancer.
Young women with colon cancer lived longer than menYounger women with metastatic colorectal cancer lived longer than younger men, revealed by researchers in a new US study. However, this survival advantage disappeared with age, suggesting a benefit from estrogen or other hormones.
Prostate cancer test age lowered to 40The age at which men are recommended to first have a test to help identify prostate cancer has been reduced from 50 to 40 years of age.
New blood test promise diagnosis of colon cancerPromising results from a new blood test that can aid in the early identification of patients with colon cancer will be presented at Europe's largest cancer congress, in Berlin today.
How diarrheal bacteria cause some colon cancers revealedJohns Hopkins scientists say they have figured out how bacteria that cause diarrhea may also be the culprit in some colon cancers. The common Bacteroides fragilis (ETBF) dupe immune system cells into permitting runaway colon tissue inflammation, a precursor for malignant growth.
Cetuximab for colorectal cancer with KRAS geneFrom a health-care system perspective, it may be more efficient to use the drug cetuximab only in colorectal cancer patients whose tumors have a wild-type KRAS gene, according to a study published online August 7 in the Journal of the National Cancer Institute.
CT colonography better for colorectal cancer screeningComputed tomographic (CT) colonography may offer patients at increased risk of colorectal cancer an alternative to colonoscopy that is less-invasive, is better-tolerated and has good diagnostic accuracy.
Evaluating risk factors of sporadic colorectal cancerColorectal cancer (CRC) is one of the most common cancers in China. Although the association between the epidemiological factors and sporadic colorectal cancer is not known and still remains uncertain.
Colorectal cancer rising in young adults 20-29 years in USA new study finds that in sharp contrast to the overall declining rates of colorectal cancer in the United States, incidence rates among adults younger than age 50 years are increasing.
Advance in bowel cancer test research - gene expression biomarkersAustralian researchers have developed gene expression biomarkers which can accurately discriminate pre-cancerous and cancerous colorectal growths from non-cancerous controls.
Surgery not necessary for most late stage colorectal cancersA new study shows that a large majority of patients who present with advanced colorectal cancer that has spread to other organs (stage IV) don't require immediate surgery to remove the primary tumor in the colon.
Gene linked to Celebrex treatment for colon tumor preventionA new study finds that individuals who have low expression of the "Celebrex gene," 15-PGDH, are actually resistant to Celebrex treatment when used to prevent colon cancer.
Hormone therapy reduces woman's risk of colorectal cancer by 40%In a large study, a national team of researchers led by Mayo Clinic scientists observed that self-reported use of hormone therapy was associated with a significantly lower colorectal cancer risk. However, the mechanisms for the apparent protective association are still unclear.
Benefits from screening colonoscopy limitedScreening colonoscopy is associated with fewer deaths from colorectal cancer, and the association is primarily limited to deaths from cancer developing in the left side of the colon, revealed by researchers.
Smoking increases colorectal cancer riskAn analysis of previous studies indicates that smoking is significantly associated with an increased risk for colorectal cancer and death, according to an article in the December 17 issue of JAMA.
Colonoscopy's limitation for right sided colon cancerA new study finds that colonoscopy is strongly associated with fewer deaths from colorectal cancer. However, the risk reduction appears to be entirely due to a reduction in deaths from left-sided cancers.
Colorectal cancer rate declines in USThe American Society for Gastrointestinal Endoscopy (ASGE) heralds the recent news of a decline in U.S. cancer deaths and incidence rates, with colorectal cancer among the top three cancers with significant declines.
Colonoscopy associated with reduced colorectal cancer incidencePatients who undergo a complete negative colonoscopy have a reduced incidence of colorectal cancer, confirms a study published in Clinical Gastroenterology and Hepatology.
Colon cancer's genetic link to obesityA new study reveals the first-ever genetic link between obesity and colon cancer risk, a finding that could lead to greater accuracy in testing for the disease, said a researcher at the University of Alabama at Birmingham (UAB).
CT colonography a viable colorectal cancer screening optionDeath from colorectal cancer is highly preventable with effective screening and early detection. Many screening options are available, each with advantages and disadvantages, but half of eligible patients still do not participate in colorectal cancer screening.
A genetic trait identified for colorectal cancer riskScientists at Northwestern University's Feinberg School of Medicine and colleagues have discovered a genetic trait that is present in 10 to 20 percent of patients with colorectal cancer. The findings strongly suggest that the trait is a major contributor to colorectal cancer risk and likely the most common cause of colorectal cancer to date.
Aspirin may reduce breast cancer by 20%Anti-inflammatory drugs like aspirin may reduce breast cancer by up to 20 per cent, according to an extensive review carried out by experts at London's Guy's Hospital and published in the March issue of IJCP, the International Journal of Clinical Practice.
Colorectal cancer screening guidelines updateA new guideline on colorectal cancer screening released by an expert group representing a broad spectrum of health care organizations, including the American College of Gastroenterology (ACG), the American Society for Gastrointestinal Endoscopy (ASGE) and the American Cancer Society (ACS), offers recommendations for various alternatives for colorectal cancer detection and states a strong preference for screening tests that can prevent colorectal cancer.
Red meat consumption linked to colorectal cancerFor most Americans, meals tend to center around meat. To significantly decrease a person's risks of developing colorectal cancer, experts at The University of Texas M. D. Anderson Cancer Center suggest a new approach to meal planning that focuses more on fruit and vegetable dishes.
Bowel cancer rising in Australia, reports AIHWA new Australian report released by the Australian Institute of Health and Welfare (AIHW) presents a mixed bag on favourable and unfavourable trends in chronic diseases over time. The report, Indicators for chronic disease and their determinants, 2008, focuses on the 12 chronic conditions that represent a large burden of disease in Australia.
Colorectal cancer deaths are down in USNew data revealing decreasing trends in cancer deaths in the United States overall, and in colorectal cancer deaths in particular, highlight the remarkable benefits of colorectal cancer screening tests, but the lifesaving potential of these tests is unrealized for many Americans, according to experts from the American College of Gastroenterology.
Colonoscopy fears overcome when patients support patientsPatients who have had a colonoscopy can play a life-saving role by encouraging other patients to follow through with their own colorectal cancer screenings, according to new research from the University of Pennsylvania School of Medicine. These peer coaches can provide important information to combat myths and fears that serve as barriers to colonoscopy – issues patients say their doctors often fail to address.
Colon cancer screenings could pose harm to someEven though current guidelines advocate colorectal cancer screenings for those with severe illnesses, they may bring little benefit and may actually pose harm, according to a recent study by Yale School of Medicine researchers published in the Archives of Internal Medicine.
41 Rectal Cancer articles listed above.