Therapeutic

Therapeutic - most related articles:

- Therapeutic cloning may treat Parkinson's disease - 2.6
- Cooling may benefit children after cardiac arrest - 2.3
- SAP a new therapeutic target in Alzheimer's disease - 2

Therapeutic articles

New drug targets aimed at slowing progression of HIV AIDS
Researchers reveal a mechanism by which the immune system tries to halt the spread of HIV. Harnessing this mechanism may open up new paths for therapeutic research aimed at slowing the virus' progression to AIDS.

Substantial recovery in headache with placebo treatment
Headache is a very common complaint, with over 90% of all persons experiencing a headache at some time in their lives. Headaches commonly are tension-type (TTH) or migraine. They have high socioeconomic impact and can disturb most daily activities.

Allergan agreed to pay $600 million to US Government
Allergan, Inc. (NYSE: AGN) announced that it has reached a resolution with the United States Department of Justice (DOJ) regarding the previously reported Government investigation into Allergan's past U.S. sales and marketing practices relating to certain therapeutic uses of BOTOX(R) (onabotulinumtoxinA).

Molecular mechanism triggering Parkinson's disease identified
Scientists at the Stanford University School of Medicine have identified a molecular pathway responsible for the death of key nerve cells whose loss causes Parkinson's disease. This discovery not only may explain how a genetic mutation linked to Parkinson's causes the cells' death, but could also open the door to new therapeutic approaches for the malady.

New drug improves symptoms in autism disorder
Researchers from Mount Sinai School of Medicine have identified a drug that improves communication between nerve cells in a mouse model of Phelan McDermid Syndrome (PMS). Behavioral symptoms of PMS fall under the autism spectrum disorder category.

Cooling may benefit children after cardiac arrest
When the heart is stopped and restarted, the patient's life may be saved but their brain is often permanently damaged. Therapeutic hypothermia, a treatment in which the patient's body temperature is lowered and maintained several degrees below normal for a period of time, has been shown to mitigate these harmful effects and improve survival in adults.

Pain relief drugs may encourage cancer growth
Opiate-based painkillers like morphine can stimulate the growth and spread of cancer cells, revealed by researchers.

Gene therapy may improve vision in congenital blindness LCA
Researchers from the University of Pennsylvania School of Medicine and the Center for Cellular and Molecular Therapeutics at the Children's Hospital of Philadelphia have used gene therapy to safely improve vision in five children and seven adults with a rare form of congenital blindness.

Orexigen's Contrave trials successful for obesity treatment
Orexigen Therapeutics, Inc. (Nasdaq: OREX) announced that all three remaining Phase 3 trials evaluating Contrave(R) (bupropion SR/naltrexone SR), its investigational drug for the treatment of obesity, met their co-primary endpoints.

Immunotherapy with vaccine improves advanced melanoma
A vaccine for one of the most lethal cancers, advanced melanoma, has shown improved response rates and progression-free survival for patients when combined with the immunotherapy drug, Interleukin-2, according to researchers from The University of Texas M. D. Anderson Cancer Center.

$24 million for rare and neglected diseases research
The National Institutes of Health is launching the first integrated, drug development pipeline to produce new treatments for rare and neglected diseases. The $24 million program jumpstarts a trans-NIH initiative called the Therapeutics for Rare and Neglected Diseases Program, or TRND.

New drug to improve walking ability in multiple sclerosis people
Acorda Therapeutics, Inc. (Nasdaq: ACOR) announced that the U.S. Food and Drug Administration (FDA) has accepted the Fampridine-SR New Drug Application (NDA) for filing, assigning Priority Review and a Prescription Drug User Fee Act (PDUFA) date of October_22, 2009.

Major advance in stem cell reprogramming technology
In a paper publishing online April 23rd in Cell Stem Cell, a Cell Press journal, Dr. Sheng Ding and colleagues from the Scripps Research Institute in La Jolla, California, report an important step forward in the race to make reprogrammed stem cells that may be better suited for use in clinical settings.

Nanotechnology offers new cancer breakthrough hope
A multi-disciplinary team of scientists from the University of Leicester could be potentially paving the way for the development of a powerful new strategy for both the early diagnosis and treatment of prostate cancer.

SAP a new therapeutic target in Alzheimer's disease
New therapeutic approaches in Alzheimer's disease are urgently needed. Work led by Professor Mark Pepys FRS over more than 20 years has identified a protein known as serum amyloid P component (SAP) as a possible therapeutic target in Alzheimer's disease.

Brain cancer malignant glioma linked to gene mutations
Scientists at Duke University Medical Center and Johns Hopkins University have discovered mutations in two genes that could become therapeutic targets in malignant glioma, a dangerous class of brain tumors.

ATryn from milk of goats approved to treat hereditary antithrombin deficiency
The U.S. Food and Drug Administration issued its first approval for a biological product produced by genetically engineered (GE) animals.

Animal eggs not suitable to produce stem cells
Since the cloning of Dolly the Sheep over a decade ago, somatic cell nuclear transfer (SCNT) has been considered a promising way to generate human, patient-specific stem cells for therapeutic applications.

Fatty acids linked to Alzheimer's disease
Scientists at the Gladstone Institute of Neurological Disease (GIND) and the University of California have found that complete or partial removal of an enzyme that regulates fatty acid levels improves cognitive deficits in a mouse model of Alzheimer's disease (AD).

Acupuncture reduces side effects of breast cancer treatment
Acupuncture is as effective and longer-lasting in managing the common debilitating side effects of hot flashes, night sweats, and excessive sweating (vasomotor symptoms) associated with breast cancer treatment and has no treatment side effects compared to conventional drug therapy, according to a first-of-its-kind study presented September 24, 2008, at the American Society for Therapeutic Radiology and Oncology's 50th Annual Meeting in Boston.

Novel approach to treat Alzheimer's disease
JADO Technologies GmbH, the leading developer of RAFT intervention therapeutics, announced the publication of a paper in Science demonstrating a potential novel strategy for therapeutic intervention in Alzheimer's and other diseases by targeting discrete sub-compartments in the cell membrane (RAFTS).

Bitter melon for type 2 diabetes patients
Scientists have uncovered the therapeutic properties of bitter melon, a vegetable and traditional Chinese medicine, that make it a powerful treatment for Type 2 diabetes.

Therapeutic cloning may treat Parkinson's disease
Research led by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) has shown that therapeutic cloning, also known as somatic-cell nuclear transfer (SCNT), can be used to treat Parkinson's disease in mice.

Possible treatment target for alcohol dependence identified
A brain circuit that underlies feelings of stress and anxiety shows promise as a new therapeutic target for alcoholism, according to new studies by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH).

American physicians supporting marijuana research
Marijuana has been smoked for its medicinal properties for centuries. Preclinical, clinical, and anecdotal reports suggest numerous potential medical uses for marijuana. Although the indications for some conditions have been well documented, less information is available about other potential medical uses.

Pancreatic stem cells may cure diabetes
Just as many scientists had given up the search, researchers have discovered that the pancreas does indeed harbor stem cells with the capacity to generate new insulin-producing beta cells. If the finding made in adult mice holds for humans, the newfound progenitor cells will represent "an obvious target for therapeutic regeneration of beta cells in diabetes," the researchers report in the Jan. 25 issue of Cell, a publication of Cell Press.

Intelence, etravirine HIV Drug approved in US
US FDA approved Tibotec Therapeutics' Intelence, etravirine tablets for the treatment of HIV infection, to be used in combination with other anti-HIV medications, in adults who have failed treatment with other antiretrovirals.

273 human proteins required for HIV propagation
Current drugs attack HIV itself, leaving patients vulnerable to counterattack by the rapidly mutating virus, which often evolves resistance. But the human proteins exploited by HIV represent potential therapeutic targets that could avoid this problem. The challenge will be to develop drugs that inhibit HIV by interacting with these human proteins without hurting our cells.

Sickle cell anemia treated with stem cells
MIT researchers have successfully treated mice with sickle-cell anemia in a process that begins by directly reprogramming the mice's own cells to an embryonic-stem-cell-like state, without the use of eggs.

Treatment of HIV associated Lipodystrophy Syndrome
Researchers in Montreal and Boston have identified a potential new treatment for the HIV/HAART*-associated Lipodystrophy Syndrome. This syndrome is a common side-effect of anti-retroviral medications to treat HIV infection.

30 Therapeutic articles listed above.

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