Therapy
Hepatitis C declines health with liver diseaseAn NIH funded multi-center clinical trial found no benefit from "maintenance therapy," low-dose peginterferon used for hepatitis C patients who have not responded to an initial round of treatment.
New treatment may cure food allergiesA team of scientists from across Europe are embarking on new research to develop a treatment for food allergy.
International Society for Stem Cell Research releases new guidelinesThe International Society for Stem Cell Research (ISSCR), the world's leading professional organization of stem cell researchers, released new guidelines for the responsible development of safe and effective stem cell therapies for patients.
Whooping cough booster for parents of newbornsA booster vaccination for parents of new babies and other household members may be the most effective way of preventing the fatal form of whooping cough in young infants, say a group of paediatric intensive care doctors on bmj.com today.
14 drugs identified for off label usePhysicians and policy-makers know that drugs are frequently prescribed to treat certain diseases despite a lack of FDA approval - a practice known as off-label prescribing. Yet they say the problem is so big they don't know how to begin tackling it.
Diabetes drug rosiglitazone linked to higher heart failure riskOlder adults who take the diabetes medication rosiglitazone appear to have a higher risk of death and heart failure than those taking the related medication pioglitazone, according to a report in the November 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Psychotherapy improves survival for breast cancer patientsA new study finds that breast cancer patients who participate in intervention sessions focusing on improving mood, coping effectively, and altering health behaviors live longer than patients who do not receive such psychological support.
Transplant of trachea made from stem cells successfulThe first operation for transplantation of a tissue-engineered airway has been successful. This procedure has massively improved the quality of life of the 30-year-old Colombian female recipient who needed the transplant after contracting tuberculosis.
A man defeated HIV virus through bone marrow transplantAn HIV-positive person, who underwent a bone marrow transplant to treat leukemia, has had undetectable HIV viral loads for almost two years. HIV-positive man was ill from leukemia and had underwent treatment by the team led by Prof. Eckhard Thiel, director of the Medical Clinic with a focus on hematology and oncology.
Fiber, antispasmodics and peppermint oil to treat IBSFibre, antispasmodics and peppermint oil are all effective therapies for irritable bowel syndrome (IBS) and should become first-line treatments, according to a study on bmj.com.
TIM 3 protein turns off HIV fighting T cellsIn HIV-infected patients the body's immune system is unable to fight off the virus. A new study to be published online on November 10th in the Journal of Experimental Medicine shows that T cells in HIV-infected individuals express a protein called TIM-3, which inactivates their virus killing capacity.
Factors identified causing barriers to asthma careBarriers to managing asthma include access to appropriate care, patient adherence, distrust of the medical profession, delayed asthma diagnosis, culture, lifestyle choices and genetic discrepancies according to experts at the annual meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in Seattle.
Bone marrow transplant can cure sickle cell diseaseA unique approach to bone marrow transplantation pioneered in part by a Children's Hospital of Pittsburgh of UPMC physician has proven to be the only safe and effective cure for sickle cell disease, according to a new study.
HIV infected patients should start HAART soonerUnder current treatment guidelines, highly active antiretroviral therapy (HAART) should be considered for HIV-infected patients when their CD4+ T-cell counts fall below 350 cells per cubic millimeter (mm3).
New genes identified linked to lung cancerWorking as part of a multi-institutional collaboration, scientists at Washington University School of Medicine in St. Louis have assembled the most complete catalog to date of the genetic changes underlying the most common form of lung cancer.
Estimating lives lost due to delay in HIV drug use in South AfricaMore than 330,000 lives were lost to HIV/AIDS in South Africa from 2000 and 2005 because a feasible and timely antiretroviral (ARV) treatment program was not implemented, assert researchers from the Harvard School of Public Health (HSPH) in a study published online by the Journal of Acquired Immune Deficiency Syndromes (JAIDS) (http://www.jaids.com/).
Live cell therapy clinical trial in New Zealand for diabeticsLiving Cell Technologies Limited (ASX: LCT; OTCQX: LVCLY) announced that New Zealand Health Minister, the Honorable David Cunliffe, has approved an application from the company to conduct in New Zealand a Phase I/IIa clinical trial of DiabeCell®, LCT's lead product candidate for the treatment of insulin dependent (Type 1) diabetes.
Antiretrovirals with TB treatment reduces mortality in HIV patientsA South African treatment study conducted by researchers in the Department of Epidemiology at the Mailman School of Public Health shows that mortality among TB-HIV co-infected patients can be reduced by a remarkable 55%, if antiretroviral therapy (ART) is provided with TB treatment at the same time.
21st century could be the age of paranoiaParanoia is on the increase and could go unchecked unless we take urgent action, claims a leading scientist. Dr Daniel Freeman, a Wellcome Trust fellow, warns that changes in how we live and work could mean that we are entering an "age of paranoia."
Updated labeling for psoriasis drug Raptiva approvedThe U.S. Food and Drug Administration announced labeling changes, including a Boxed Warning, to highlight the risks of life-threatening infections, including progressive multifocal leukoencephalopathy (PML), with the use of Raptiva (efalizumab).
$19 Million to M. D. Anderson for breast cancer researchThe University of Texas M. D. Anderson Cancer Center has received nearly $19 million in grants from Susan G. Komen for the Cure® as part of that organization's new initiative to fast-track promising research to benefit breast cancer patients.
Nicotine gum for pregnant smokersNicotine gum might help pregnant women to reduce the number of cigarettes they smoke, which could reduce their risk of having premature or low-birthweight infants.
Heart patients should be screened, treated for depressionHeart patients should be screened for depression -- a common condition that can profoundly affect both prognosis and quality of life -- according to the American Heart Association's first scientific statement on depression and coronary heart disease.
Psychotherapy more beneficial for treatment of mental disordersPsychodynamic psychotherapy lasting for at least a year is effective and superior to shorter-term therapy for patients with complex mental disorders such as personality and chronic mental disorders, according to a meta-analysis published in the October 1 issue of JAMA.
Vitamin C supplements reduce benefits of anti cancer drugsIn pre-clinical studies, vitamin C appears to substantially reduce the effectiveness of anticancer drugs, say researchers at Memorial Sloan-Kettering Cancer Center.
HIV began spreading among humans between 1884 and 1924New research indicates that the most pervasive global strain of HIV began spreading among humans between 1884 and 1924, suggesting that growing urbanization in colonial Africa set the stage for the HIV/AIDS pandemic.
No increased risk of heart attacks in users of HRTIt's not what you take but the way that you take it that can produce different results in women who take hormone replacement therapy (HRT), according to new research on the association between HRT and heart attacks, published online in Europe's leading cardiology journal, the European Heart Journal.
Eli Lilly's Alimta approvad for lung cancerEli Lilly and Company (NYSE: LLY) announced that it received approval from the U.S. Food and Drug Administration (FDA) for the use of ALIMTA(R) (pemetrexed for injection), in combination with cisplatin, in the first-line treatment of locally-advanced and metastatic non-small cell lung cancer (NSCLC), for patients with nonsquamous histology.
1 week radiation effective breast cancer treatmentAccelerated partial breast irradiation (APBI) using a type of radiation seed implants called balloon brachytherapy is as effective in keeping breast cancer from coming back as the standard external beam radiation treatment.
Acupuncture reduces side effects of breast cancer treatmentAcupuncture is as effective and longer-lasting in managing the common debilitating side effects of hot flashes, night sweats, and excessive sweating (vasomotor symptoms) associated with breast cancer treatment and has no treatment side effects compared to conventional drug therapy, according to a first-of-its-kind study presented September 24, 2008, at the American Society for Therapeutic Radiology and Oncology's 50th Annual Meeting in Boston.
Audio relaxation program may help lower blood pressureAn audio relaxation program lowered blood pressure more than a Mozart sonata in a group of elderly people with high blood pressure, researchers reported at the American Heart Association's 62nd Annual Fall Conference of the Council for High Blood Pressure Research.
Electronic cigarette not a safe or proven quitting method for smokersContrary to what some marketers of the electronic cigarette imply in their advertisements, the World Health Organization (WHO) does not consider it to be a legitimate therapy for smokers trying to quit.
Lumpectomy, radiation improve life in breast cancer patientsWomen with breast cancer who are treated with lumpectomy and radiation report a high level of overall quality of life several years after treatment that is comparable to a general sampling of the adult women U.S. population according to a survey conducted by physicians at Fox Chase Cancer Center.
Chemotherapy target found for leukemiaCancer researchers at the Stanford University School of Medicine have discovered a promising new chemotherapy target for a deadly form of leukemia. Their discovery hinges on a novel "double agent" role for a molecular signal that regulates cell growth.
Poor oral hygiene, bleeding gums may cause heart diseasePeople with poor dental hygiene and those who don't brush their teeth regularly end up with bleeding gums, which provide an entry to the bloodstream for up to 700 different types of bacteria found in our mouths.
Arthroscopy may not help osteoarthritis patientsArthroscopic surgery for osteoarthritis of the knee provides no additional benefit to optimized physical and medical therapy, revealed by researchers in a study published in the New England Journal of Medicine (NEJM) issue of Sept. 11, 2008.
Nplate bone marrow stimulator approved to treat low platelet countsThe U.S. Food and Drug Administration approved Nplate (romiplostim), the first product that directly stimulates the bone marrow to produce needed platelets in patients with a rare blood disorder that can lead to serious bleeding.
Alexander technique offers long-term relief for back painAlexander technique lessons in combination with an exercise programme offer long-term effective treatment for chronic back pain, according to a study published on BMJ.com.
HIV people not tested for tuberculosisA mere 1% of people living with HIV/AIDS are reported to have been screened for TB, according to the most recent global data available from the World Health Organization. Health experts and activists at the International AIDS Conference are calling upon HIV/AIDS programs and international donors to ensure universal TB screening of every person who has tested positive for HIV.
Breast cancer relapse risk low after 5 yearsBreast cancer survivors continue to have a substantial risk of disease recurrence after five years of systemic therapy, according to a study published in the August 12 online issue of the Journal of the National Cancer Institute.
BIO welcomes advances in stem cell researchBiotechnology Industry Organization (BIO) President and CEO Jim Greenwood issued the following statement regarding the news that researchers at the Harvard Stem Cell Institute created 20 disease-specific stem cell lines thru the new induced pluripotent stem cell (iPS) technique:
Lower cholesterol early in lifeWith heart disease maintaining top billing as the leading cause of death in the United States, a team of University of California, San Diego School of Medicine physician-researchers is proposing that aggressive intervention to lower cholesterol levels as early as childhood is the best approach available today to reducing the incidence of coronary heart disease.
Vitamin C injections slow tumor growthHigh-dose injections of vitamin C, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate by about 50 percent in mouse models of brain, ovarian, and pancreatic cancers, researchers from the National Institutes of Health (NIH) report in the August 5, 2008, issue of the Proceedings of the National Academy of Sciences.
International AIDS Society updates treatment guidelines for HIV infectionAn evaluation of recent data has led to an update in the guidelines and recommendations for antiretroviral treatment of adult human immunodeficiency virus (HIV) infection, according to an article in the August 6 issue of JAMA, a theme issue on HIV/AIDS.
People with sleep apnea have a high mortality riskPeople with severe sleep apnea have a much higher mortality risk than people without sleep apnea, and this risk increases when sleep apnea is untreated.
Joint replacement improves osteoarthritis in older adultsOlder adults who have hip or knee replacement surgery for severe osteoarthritis may take several weeks to recover but appear to have excellent long-term outcomes, according to a report in the July 14 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Boxed warnings on fluoroquinolone antimicrobial drugsThe U.S. Food and Drug Administration (FDA) requests boxed warnings on fluoroquinolone antimicrobial drugs. FDA seeks this to strengthen warnings concerning increased risk of tendinitis and tendon rupture.
Cold sore's herpes simplex virus mechanism revealedNow that Duke University Medical Center scientists have figured out how the virus that causes cold sores hides out, they may have a way to wake it up and kill it.
Canadian woman acquires new accent after strokeA canadian woman in southern Ontario is one of the first cases in Canada of a rare neurological syndrome (foreign accent syndrome) in which a person starts speaking with a different accent, McMaster University researchers report in the July issue of the Canadian Journal of Neurological Sciences.
New therapy promising for melanoma skin cancerThe combination of two different biotherapies (interferon alfa-2b and tremelimumab) may be beneficial for patients with inoperable melanoma, revealed by researchers in US.