Trial

Trial - most related articles:

- Single PILL may prevent heart disease - 2.5
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Trial articles

Stroke risk greater for older women with atrial fibrillation
In a study that examined use of the anticoagulant medication warfarin and risk of stroke following a diagnosis of atrial fibrillation in older patients, women, especially those 75 years or older, had a higher risk of stroke than men, regardless of their risk profile and use of warfarin, suggesting that current anticoagulant therapy to prevent stroke might not be sufficient for older women.

Brain cancer vaccine prepared from brain tumor proves effective
A new brain cancer vaccine tailored to individual patients by using material from their own tumors has proven effective in a multicenter phase 2 clinical trial at extending their lives by several months or longer. The patients suffered from recurrent glioblastoma multiforme-which kills thousands of Americans every year.

Heart failure patients may get benefit from testosterone supplements
Testosterone supplements helped heart failure patients breathe better and exercise more. This new research analyzed four randomized clinical trials of patients with moderate to severe chronic heart failure. Patients were given commercial testosterone supplements by injection, patch or gel.

Bariatric surgery improves and reverses diabetes
Overweight, diabetic patients who underwent bariatric surgery achieved significant improvement or remission of their diabetes.In a randomized, controlled trial, some weight loss surgery patients achieved normal blood sugar levels without use of any diabetes medications.

Alzheimer's Disease patients may not get benefit from antioxidants
An antioxidant combination of vitamin E, vitamin C and a-lipoic acid (E/C/ALA) was not associated with changes in some cerebrospinal fluid biomarkers related to Alzheimer disease in a randomized controlled trial, revealed by researchers.

New technique for screening breast cancer using ultrasound
Scientists have successfully completed an initial trial of a new, potentially more reliable, technique for screening breast cancer using ultrasound. The team at the National Physical Laboratory (NPL), the UK's National Measurement Institute, working with the University Hospitals Bristol NHS Foundation Trust, are now looking to develop the technique into a clinical device.

CT colonography a front line colorectal cancer screening tool for seniors
Computerized tomographic (CT) colonography (CTC), also known as virtual colonoscopy, is comparable to standard colonoscopy in its ability to accurately detect cancer and precancerous polyps in people ages 65 and older.

Regorafenib improves survival of colorectal cancer patients
Regorafenib - an investigational drug - slowed the progression of tumors and lengthened the lives of patients with metastatic colorectal cancer. This is the first novel agent in eight years to show improvement in overall survival of colon cancer patients who have run out of treatment options.

New cancer drug development institute at UT MD Anderson
Academic and government leaders announced the establishment of a major new research institute at The University of Texas MD Anderson Cancer Center that will blend the best attributes of academic and industrial research to identify and validate new cancer targets, convert such scientific knowledge into new cancer drugs, and advance these novel agents into innovative clinical trials.

Transcatheter aortic valve replacement TAVR shows superiority in heart patients
A two-year study of patients in the landmark PARTNER trial, which compared transcatheter aortic valve replacement (TAVR) in patients who have severe aortic stenosis and are not candidates for open heart surgery, confirm the one-year findings and support the role of TAVR as the standard of care.

CCSVI role in multiple sclerosis seems to be controversial
Chronic cerebrospinal venous insufficiency (CCSVI) appears to be more common in people with multiple sclerosis than in people without the condition, states a review of published studies in CMAJ (Canadian Medical Association Journal).However, there are not enough high-quality studies to allow definitive conclusions.

Hormonal contraception doubles HIV risk in Africa
Women using hormonal contraception -- such as a birth control pill or a shot like Depo-Provera – are at double the risk of acquiring HIV, and HIV-infected women who use hormonal contraception have twice the risk of transmitting the virus to their HIV-uninfected male partners.

Expandable prosthesis resolves advanced aortic valve disease
Among individuals 65 years and older, as many as 30 percent have aortic valve sclerosis or stenosis and as a result of their deteriorating health, they cannot enjoy a normal lifestyle.

Alpharadin improved survival in advanced prostate cancer patients
Until recently, options for patients with bone metastases from advanced prostate cancer have been very limited. But now the first Phase III study of an alpha-pharmaceutical in these patients has shown that it can prolong survival significantly, according to research reported recently at the 2011 European Multidisciplinary Cancer Congress.

Stroke clinical trial finds intensive medical treatment better than brain stent
Patients at a high risk for a second stroke who received intensive medical treatment had fewer strokes and deaths than patients who received a brain stent in addition to the medical treatment, a large nationwide clinical trial has shown.

Rivaroxaban can prevent strokes in atrial fibrillation patients
Rivaroxaban, an anti-clotting drug, was shown to be an attractive alternative to warfarin in the prevention of stroke in patients with atrial fibrillation, revealed by researchers recently.

Massage therapy helps ease chronic low back pain
The hour-long massage treatments (structural and relaxation massage) help people with back pain to function even after six months, reported in a new research. People who have persistent back pain may want to consider massage as an option.

20% reduction in lung cancer mortality with low dose CT vs chest X ray
Scientists have found a 20 percent reduction in deaths from lung cancer among current or former heavy smokers who were screened with low-dose helical computed tomography (CT) versus those screened by chest X-ray. The primary research results from the National Lung Screening Trial (NLST) were published in the New England Journal of Medicine.

FDA panel votes to revoke approval for Avastin for advanced breast cancer
The Oncologic Drugs Advisory Committee, FDA, USA disapproved the Avastin which cited a lack of survival benefit. Now as two more trials have been analyzed -- neither showing a survival benefit -- the FDA stated that in the balance, the benefit did not outweigh the harm.

Abatacept and GAD-alum to slow progression of type 1 diabetes
Abatacept (Orencia), an immune system modulator and GAD-alum, an antigen based therapy found beneficial for patients with type 1 diabetes. TrialNet researchers are conducting a series of studies to test ways to prevent or delay progression of type 1 diabetes. Results of two studies testing drugs to slow or stop the immune system's attack on insulin-producing cells in people newly diagnosed with type 1 diabetes will be presented at the American Diabetes Association's (ADA) 71st Scientific Sessions in San Diego and simultaneously published online in the Lancet.

Lithium may prevent brain damage in patients with Parkinson's disease
Researcher are focusing on lithium as a potential treatment for Parkinson's disease -- PD -- as well as its efficacy in combination with drugs currently used to control the symptoms of the disease. Lithium profoundly prevents the aggregation of toxic proteins and cell loss associated with Parkinson's disease (PD) in a mouse model of the condition.

Ovarian cancer screening does not improve survival
In a clinical trial that included nearly 80,000 women, those who received ovarian cancer screening did not have a reduced risk of death from ovarian cancer compared to women who received usual care, but did have an increase in invasive medical procedures and associated harms as a result of being screened.

Pfizer drug reduces breast cancer in high risk women
The drug exemestane significantly reduces the risk of breast cancer in high-risk, postmenopausal women is the result of an international, randomized double-blind phase III clinical trial in which University at Buffalo researchers and hundreds of Western New York women played a critical role, revealed at the American Society of Clinical Oncology annual meeting.

Niacin and statin treatment did not protect heart
The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped a clinical trial studying a blood lipid treatment 18 months earlier than planned.

New class of cancer drugs could work in colon cancers with genetic mutation
A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.

Stem cells repair heart damage in a human trial
Researchers have shown for the first time that stem cells injected into enlarged hearts reduced heart size, reduced scar tissue and improved function to injured heart areas, according to a small trial published in Circulation Research: Journal of the American Heart Association.

Omalizumab relieves seasonal asthma attacks in youth
A drug that targets the antibody immunoglobulin E (IgE), a key player in asthma, nearly eliminated seasonal increases in asthma attacks and decreased asthma symptoms among young people living in inner city environments, a clinical trial sponsored by the National Institutes of Health has found.

Stroke survivors with irregular heartbeat may have higher risk of dementia
Stroke survivors who have an irregular heartbeat called atrial fibrillation may be at higher risk of developing dementia than stroke survivors who do not have the heart condition, according to research published in the March 8, 2011, print issue of Neurology®, the medical journal of the American Academy of Neurology.

Fetal surgery better in treating children with spina bifida
Thirty years ago, the first human fetal surgery was performed at the University of California, San Francisco. Now, a randomized controlled trial has proven definitively that fetal surgery can help certain patients before birth.

New drug for melanoma skin cancer patients soon
Plexxikon Inc. announced positive data from an interim analysis of the BRIM3 trial, a large multi-center Phase 3 clinical study of PLX4032 (RG7204) in patients with previously untreated metastatic melanoma with the BRAF mutation.

International clinical trial tests targeted drug for melanoma skin cancer
Rush University Medical Center has just enrolled the first U.S. patient in an international clinical trial testing a novel drug to treat certain kinds of melanoma, a deadly skin cancer that in its advanced stages currently has few effective treatments.

US company starts clinical trial using stem cells to treat macular degeneration
Advanced Cell Technology, Inc. ("ACT"; OTCBB:ACTC) announced that the US Food and Drug Administration (FDA) has cleared the Company's Investigational New Drug (IND) application to immediately initiate a Phase I/II multicenter clinical trial using retinal cells derived from human embryonic stem cells (hESCs) to treat patients with Stargardt's Macular Dystrophy (SMD), one of the most common forms of juvenile macular degeneration in the world.

Clinical trial of human embryonic stem cell therapy in US
Geron Corporation (Nasdaq: GERN) announced the enrollment of the first patient in the company's clinical trial of human embryonic stem cell (hESC)-derived oligodendrocyte progenitor cells, GRNOPC1.

Genetic patterns may predict osteoarthritis
Scientists from University of North Carolina at Chapel Hill School of Medicine and Interleukin Genetics, Inc. announced findings from a large clinical study to evaluate the role played by genetic factors in the worsening of osteoarthritis.

Avandia use is restricted for diabetes patients
FDA will restrict the use of the diabetes drug Avandia (rosiglitazone) to patients with Type 2 diabetes who cannot control their diabetes on other medications. Avandia may elevate risk of cardiovascular events, such as heart attack and stroke.

Initial trials on new ovarian cancer tests exhibit extremely high accuracy
Scientists at the Georgia Institute of Technology have attained very promising results on their initial investigations of a new test for ovarian cancer. Using a new technique involving mass spectrometry of a single drop of blood serum, the test correctly identified women with ovarian cancer in 100 percent of the patients tested. The results can be found online in the journal Cancer Epidemiology, Biomarkers, & Prevention Research.

Ipilimumab demonstrates improved survival in metastatic melanoma
Bristol-Myers Squibb Company (NYSE: BMY) announced positive results from a Phase 3 randomized, double blind study of ipilimumab which demonstrated that overall survival (OS) was significantly extended in patients with previously-treated metastatic melanoma who received ipilimumab.

Education of clinicians improves prescribing for high blood pressure patients
Academic detailing-a method involving face-to-face education of clinicians by investigators trained to present trial findings and guidelines-may have been associated with a small change in prescribing patterns for patients with high blood pressure, according to a report in the May 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Pregnancy doubles HIV risk in men
A new study finds that pregnancy is a time when men are at greater risk. In fact, their risk doubles if their partner is both HIV-infected and pregnant.

Ablation heart procedure reduces risk of Alzheimer and stroke
Researchers found that ablation treatment can eliminate serious risks associated with atrial fibrillation. New research was presented at National Heart Rhythm Society.

Eating nuts improve blood cholesterol levels
Consuming more nuts appears to be associated with improvements in blood cholesterol levels, according to a pooled analysis of data from 25 trials reported in the May 10 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Artificial pancreas successfully controls blood sugar more than 24 hours
An artificial pancreas system that closely mimics the body's blood sugar control mechanism was able to maintain near-normal glucose levels without causing hypoglycemia in a small group of patients.

Choosing VBAC or plan a repeat cesarean delivery
An independent panel convened this week by the National Institutes of Health confronted a troubling fact that pregnant women currently have limited access to clinicians and facilities able and willing to offer a trial of labor after previous cesarean delivery because of so-called VBAC bans.

Pneumococcal vaccine offers protection to HIV infected
A clinical trial of a vaccine against a major cause of pneumonia and meningitis has shown that it can prevent three out of four cases of re-infection in HIV-infected adults in Africa.

Ethosuximide is preferred for childhood epilepsy
The first comprehensive comparative effectiveness clinical trial of three widely used anti-seizure drugs for childhood absence epilepsy – the most common form of epilepsy in kids – has established an evidence-based approach for initial drug therapy.

Progesterone for traumatic brain injury tested
Researchers at 17 medical centers across the US soon will begin using the hormone progesterone to treat patients who experience traumatic brain injury (TBI).

New safety controls for asthma drugs, US
The U.S. Food and Drug Administration announced that drugs in the class of long-acting beta agonists (LABAs) should never be used alone in the treatment of asthma in children or adults.

Catheter treatment works better than drugs for heart rhythm disorder
Treating a common heart rhythm disorder by burning heart tissue with a catheter works dramatically better than drug treatments, according to a landmark study published in the Jan. 27 issue of the Journal of the American Medical Association (JAMA).

Testing gene therapy for Alzheimer's disease
University Hospitals Case Medical Center is one of 12 sites conducting the first Phase 2 clinical trial of a gene therapy for Alzheimer's disease (AD). The study uses a viral-based gene transfer system called CERE-110, which is designed to deliver nerve growth factor (NGF) into the brain.

PRO 2000 anti HIV gel is ineffective
Pro 2000, a vaginal microbicide gel designed to reduce women's risk of HIV infection, showed no evidence that it reduces the risk of HIV infection, revealed by researchers at Britain's Medical Research Council (MRC).

Human Genome Sequencing decoded in India
The Council of Scientific and Industrial Research (CSIR) has achieved completion of first ever Human Genome Sequencing in India. Scientist of CSIR at the Institute of Genomics and Integrative Biology (IGIB), Delhi have sequenced the Human Genome of an anonymous healthy Indian citizen.

New 3 drug combination for multiple myeloma patients
A new three-drug combination has shown in a phase 1/2 clinical trial that it is a "highly effective regimen" in the treatment of patients newly diagnosed with multiple myeloma, a cancer of white blood cells in bone marrow, say researchers from Dana-Farber Cancer Institute.

Vioxx trial data shows early heart risk
US researchers revealed that the heart complications after taking Vioxx, the nonsteroidal anti-inflammatory drug (rofecoxib), could have been identified nearly four years before its manufacturer Merck pulled the drug from the market.

New HIV vaccine safe and effective in preventing HIV infection
In an encouraging development, an investigational vaccine regimen has been shown to be well-tolerated and to have a modest effect in preventing HIV infection in a clinical trial involving more than 16,000 adult participants in Thailand.

New treatment for melanoma shows shrinking of tumors
Researchers have made significant advances in the treatment of metastatic malignant melanoma – one of the most difficult cancers to treat successfully once it has started to spread.

Gene therapy may cure Alzheimer's disease
To stop the progression of Alzheimer's disease, scientists are conducting gene therapy trial on patients with a mild form of Alzheimer's Disease in US.

2009 H1N1 influenza vaccines in healthy adults - early results
There are encouraging reports emerging from various clinical trials of 2009 H1N1 influenza vaccines, conducted by various vaccine manufacturers. Additional companies are expected to announce their preliminary trial results shortly.

A new therapy to cure skin cancer
A potential new investigational therapy for advanced and metastatic basal cell skin cancer is revealed by researchers.

Anticoagulant Dabigatran effective in atrial fibrillation patients
The anticoagulant dabigatran is more effective than warfarin in the prevention of stroke in patients with atrial fibrillation, revealed by researchers in a study RE-LY (Randomized Evaluation of Long-term anticoagulant therapY).

Mediterranean diet and exercise lower Alzheimer's disease risk
Both being more physically active and adhering to a Mediterranean-type diet appears to be associated with reduced Alzheimer's risk, according to a new report in the August 12, 2009 issue of the Journal of the American Medical Association (JAMA).

Swine flu vaccine trials under way, UK
UK's first swine flu vaccine trials, led by the University of Leicester and University Hospitals of Leicester NHS Trust, are taking place at the Leicester Royal Infirmary.

US to launch clinical trials to test 2009 H1N1 influenza vaccine
Scientists in a network of medical research institutions across the United States are set to begin a series of clinical trials to gather critical data about influenza vaccines, including two candidate H1N1 flu vaccines.

Orexigen's Contrave trials successful for obesity treatment
Orexigen Therapeutics, Inc. (Nasdaq: OREX) announced that all three remaining Phase 3 trials evaluating Contrave(R) (bupropion SR/naltrexone SR), its investigational drug for the treatment of obesity, met their co-primary endpoints.

Lupus drug Benlysta effective for SLE patients
Human Genome Sciences, Inc. (Nasdaq: HGSI) and GlaxoSmithKline PLC (GSK) announced that BENLYSTA (belimumab, formerly LymphoStat-B®) met the primary endpoint in BLISS-52, the first of two pivotal Phase 3 trials in patients with serologically active systemic lupus erythematosus (SLE).

Breast cancer drug Abraxane promising for malignant melanoma treatment
An approved breast-cancer drug nab-paclitaxel, trade named Abraxane, has been found promising in clinical trial for the treatment of metastatic malignant melanoma, revealed by researchers.

New consensus on using APBI to treat breast cancer
A new consensus statement outlining patient selection criteria and best practices for the use of accelerated partial breast irradiation (APBI) outside the context of a clinical trial has been published in the July 15 issue of the International Journal of Radiation Oncology Biology Physics.

Prostate cancer risk from heavy drinking
In a new study, researchers examined the associations of total alcohol, type of alcoholic beverage, and drinking pattern with risks of total, low- and high-grade prostate cancer.

Sanofi's Multaq approved to treat heart rhythm disorder, US
The U.S. Food and Drug Administration has approved Sanofi's Multaq tablets (dronedarone) to help maintain normal heart rhythms in patients with a history of atrial fibrillation or atrial flutter (heart rhythm disorders or arrhythmia).

Takeda's diabetes drug alogliptin received FDA's objection
US top most health agency FDA has asked Takeda to conduct an additional clinical trial to rule out any adverse effects of alogliptin in relation to heart, that means Takeda needs to conduct a cardiovascular safety trial for alogliptin.

Prostate cancer screening may result in overdiagnosis of cancer
The recent release of two large randomized trials suggests that if there is a benefit of screening, it is, at best, small, says a new report in CA: A Cancer Journal for Clinicians.

Rheumatoid arthritis drug masitinib found effective
A clinical trial of masitinib, a drug in development for the treatment of rheumatoid arthritis, has shown it to be well tolerated and effective, revealed by researchers in BioMed Central's journal Arthritis Research and Therapy.

Success with ipilimumab in prostate cancer patients
Two Mayo Clinic patients whose prostate cancer had been considered inoperable are now cancer free thanks in part to an experimental drug therapy that was used in combination with standardized hormone treatment and radiation therapy.

Option Inferior Vena Cava Filter gets FDA clearance in US
Angiotech Pharmaceuticals, Inc. (NASDAQ: ANPI, TSX: ANP) announced that the U.S. Food and Drug Administration (FDA) has granted 510(k) clearance for the Option(TM) Inferior Vena Cava (IVC) Filter in the United States, for use in both permanent and retrievable indications.

Avandia has no increased overall heart risk
Clinical trial results presented at the American Diabetes Association annual meeting show that overall rates of cardiovascular hospitalization and cardiovascular death are similar in patients taking Avandia (rosiglitazone) compared to those receiving metformin and sulfonylurea.

Merck's heart failure drug rolofylline failed
Merck's experimental heart failure drug rolofylline failed to meet the goals in a clinical trial, failing to improve patients. Merck won't seek approval this year for this heart failure drug rolofylline after preliminary results.

Positive clinical trial results of vilazodone for depression
Clinical Data, Inc. (NASDAQ: CLDA) announced positive top-line results from the second of two Phase III trials of its investigational compound, vilazodone, for the treatment of major depressive disorder (MDD).

Breast cancer gene responds to blood pressure drug in lab
Researchers have identified a gene that is overexpressed in up to 20 percent of breast cancers and that could be blocked in the lab by a currently available blood pressure drug, according to a new study from the University of Michigan Comprehensive Cancer Center.

Vandetanib with docetaxel improve lung cancer survival
When combined with standard chemotherapy, an international Phase III trial has shown that the oral targeted therapy vandetanib improves progression-free survival for patients with advanced non-small cell lung cancer, according to research from The University of Texas M. D. Anderson Cancer Center.

Green tea shows promise in leukemia
Mayo Clinic researchers are reporting positive results in early leukemia clinical trials using the chemical epigallocatechin gallate (EGCG), an active ingredient in green tea.

$24 million for rare and neglected diseases research
The National Institutes of Health is launching the first integrated, drug development pipeline to produce new treatments for rare and neglected diseases. The $24 million program jumpstarts a trans-NIH initiative called the Therapeutics for Rare and Neglected Diseases Program, or TRND.

AIDS patients get benefit from early retroviral use
HIV-positive patients who don't seek medical attention until they have a serious AIDS-related condition can reduce their risk of death or other complications by half if they get antiretroviral treatment early on, according to a new multicenter trial led by researchers at the Stanford University School of Medicine.

Heart disorder linked to Alzheimer's disease dementia
Researchers at Intermountain Medical Center in Salt Lake City believe that they have made a breakthrough connection between atrial fibrillation, a fairly common heart rhythm disorder, and Alzheimer's disease, the leading form of dementia among Americans.

Champion clinical trial program of cangrelor discontinued
The Medicines Company (NASDAQ: MDCO) announced that it is discontinuing its Phase 3 CHAMPION clinical trial program of cangrelor in patients undergoing percutaneous coronary intervention (PCI).

Acupuncture eases chronic low back pain in SPINE trial
Acupuncture can help people with chronic low back pain feel less bothered by their symptoms and function better in their daily activities, according to the largest randomized trial of its kind, published in the May 11, 2009 Archives of Internal Medicine.

Herpes medication does not reduce HIV transmission risk
A recently completed international multi-center clinical trial has found that acyclovir, a drug widely used as a safe and effective treatment to suppress herpes simplex virus-2 (HSV-2), which is the most common cause of genital herpes, does not reduce the risk of HIV transmission when taken by people infected with both HIV and HSV-2.

New drug aims to transform malaria treatment
Ranbaxy Laboratories Limited (Ranbaxy) announced the commencement of Phase-III clinical trials for its new Anti-malaria combination drug, Arterolane maleate + Piperaquine phosphate in India, Bangladesh and Thailand.

Anti aging cosmetic reduces wrinkles
Scientists testing a cosmetic anti-ageing product sold on the high street have shown it can clinically reduce wrinkles and improve the appearance of skin damaged by everyday exposure to sunlight.

Prostate cancer immunotherapy prolongs survival
Sipuleucel-T (Provenge), an experimental immunotherapy improved survival in men with metastatic disease, according to new results to be presented April 28 at the American Urological Association (AUA) Annual Scientific Meeting in Chicago.

Boosting immune response to destroy tumours
Researchers have discovered how to trigger an improved immune response to cancer that could be included in new clinical trials that use a patient's own cells to destroy tumours.

New iPhone app allows search of all registered clinical trials
Before today, searching for one of more than 71,500 clinical trials in the National Library of Medicine and National Institutes of Health database required a chair, computer, internet connection, and a session on the government's clinical trials website.

Male circumcision surely reduces HIV risk
Three recent African trials support male circumcision for reducing the risk of contracting HIV in heterosexual men.

Plavix reduced major vascular events by 11% in heart disease
Plavix plus aspirin more effective than aspirin alone in preventing major vascular events in patients with atrial fibrillation who cannot take oral anticoagulants.

Positive results of Albuferon in Chronic Hepatitis C
Human Genome Sciences, Inc. (Nasdaq: HGSI) announced that Albuferon (albinterferon alfa-2b) met its primary endpoint of non-inferiority to peginterferon alfa-2a (Pegasys) in ACHIEVE 1, a Phase 3 clinical trial of Albuferon in combination with ribavirin in treatment-naive patients with genotype 1 chronic hepatitis C (p=0.0008).

Microbicide promising as HIV prevention method for women
A clinical trial involving more than 3,000 women in the U.S. and southern Africa demonstrates for the first time the promise of a vaginal microbicide gel for preventing HIV infection in women.

Advice for treatment of cough, colds in children under 6
Responding to guidance issued by the Medicines and Healthcare products Regulatory Agency (MHRA), advising that cough and cold treatments should not be used for children under 6 years of age, the Royal Pharmaceutical Society of Great Britain (RPSGB) has issued the following advice to parents.

Clinical trials overseas raises quality control issues
Top-tier U.S.-based pharmaceutical companies are moving their clinical trials overseas at warp speed, raising questions about ethics, quality control, and even the scientific value of their findings for people back in the U.S.

Multivitamins offer no benefit in postmenopausal women
The largest study ever conducted on postmenopausal women shows that multivitamins may offer no benefit in reducing the risk of common cancers, cardiovascular disease or overall mortality.

ViroPharma's Maribavir failed in bone marrow transplant patients
ViroPharma Incorporated (Nasdaq: VPHM) announced that its Phase 3 trial evaluating maribavir used as prophylaxis in allogeneic stem cell, or bone marrow, transplant (SCT) patients did not achieve its primary endpoint.

Anti HIV gel shows promise in preventing HIV infection in women
An investigational vaginal gel intended to prevent HIV infection in women has demonstrated encouraging signs of success in a clinical trial conducted in Africa and the United States.

Weight loss reduces urinary incontinence in overweight obese women
Reducing urinary incontinence can now be added to the extensive list of health benefits of weight loss, according to a clinical trial funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the Office of Research on Women's Health (ORWH), both part of the National Institutes of Health (NIH).

100 Trial articles listed above.

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