Virus

Hepatitis C declines health with liver disease
An NIH funded multi-center clinical trial found no benefit from "maintenance therapy," low-dose peginterferon used for hepatitis C patients who have not responded to an initial round of treatment.

HPV vaccine's hypersensitivity reactions are rare
Hypersensitivity reactions to the quadrivalent HPV vaccine (4vHPV, Gardasil) are uncommon and most schoolgirls can tolerate subsequent doses, finds the first evaluation of the quadrivalent HPV vaccine published on bmj.com.

109 medicines, vaccines in development for HIV AIDS
America's pharmaceutical research companies are testing 109 medicines and vaccines to treat or prevent HIV/AIDS and related conditions, according to a report released by the Pharmaceutical Research and Manufacturers of America (PhRMA).

£15 m for South Africa in new struggle against AIDS
South Africa's revitalised drive against AIDS today received a £15 million boost which could help save millions of lives and stop the spread of HIV across the country.

Asthma risk more in children born in autumn
Children who are born four months before the peak of cold and flu season have a greater risk of developing childhood asthma than children born at any other time of year, according to new research from Vanderbilt University Medical Center.

Routine HIV testing fails in US
While the U.S. AIDS epidemic simmers largely unnoticed by most Americans, a failure to widely implement routine HIV testing continues to fuel its spread, HIV researchers and experts said.

Gardasil HPV vaccine prevented genital lesions in men
GARDASIL [Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant], the cervical cancer vaccine from Merck & Co., Inc., prevented 90 percent of external genital lesions caused by human papillomavirus (HPV) types 6, 11, 16 and 18 in a pivotal Phase III study in men aged 16 to 26.

A man defeated HIV virus through bone marrow transplant
An HIV-positive person, who underwent a bone marrow transplant to treat leukemia, has had undetectable HIV viral loads for almost two years. HIV-positive man was ill from leukemia and had underwent treatment by the team led by Prof. Eckhard Thiel, director of the Medical Clinic with a focus on hematology and oncology.

TIM 3 protein turns off HIV fighting T cells
In HIV-infected patients the body's immune system is unable to fight off the virus. A new study to be published online on November 10th in the Journal of Experimental Medicine shows that T cells in HIV-infected individuals express a protein called TIM-3, which inactivates their virus killing capacity.

Influenza Flu trends from Google.org
By tracking the popularity of certain Google search queries, Google's engineers have discovered that they can accurately estimate the level of flu in each state, in near real time.

Stress may make you itch more
Current research suggests that stress may activate immune cells in your skin, resulting in inflammatory skin disease. The related report by Joachim et al., "Stress-induced Neurogenic Inflammation in Murine Skin Skews Dendritic Cells towards Maturation and Migration: Key role of ICAM-1/LFA-1 interactions," appears in the November issue of The American Journal of Pathology.

HIV infected patients should start HAART sooner
Under current treatment guidelines, highly active antiretroviral therapy (HAART) should be considered for HIV-infected patients when their CD4+ T-cell counts fall below 350 cells per cubic millimeter (mm3).

New MRI imaging may identify cervical cancer early
Using high-resolution magnetic resonance imaging (MRI) with a special vaginal coil, a technique to measure the movement of water within tissue, researchers may be able to identify cervical cancer in its early stages, according to a new study being published in the November issue of Radiology.

Estimating lives lost due to delay in HIV drug use in South Africa
More than 330,000 lives were lost to HIV/AIDS in South Africa from 2000 and 2005 because a feasible and timely antiretroviral (ARV) treatment program was not implemented, assert researchers from the Harvard School of Public Health (HSPH) in a study published online by the Journal of Acquired Immune Deficiency Syndromes (JAIDS) (http://www.jaids.com/).

Antiretrovirals with TB treatment reduces mortality in HIV patients
A South African treatment study conducted by researchers in the Department of Epidemiology at the Mailman School of Public Health shows that mortality among TB-HIV co-infected patients can be reduced by a remarkable 55%, if antiretroviral therapy (ART) is provided with TB treatment at the same time.

Updated labeling for psoriasis drug Raptiva approved
The U.S. Food and Drug Administration announced labeling changes, including a Boxed Warning, to highlight the risks of life-threatening infections, including progressive multifocal leukoencephalopathy (PML), with the use of Raptiva (efalizumab).

Gardasil vaccine to prevent cervical cancer in India
MSD Pharmaceuticals India announced the launch of GARDASIL Vaccine, India's first vaccine to help prevent Cervical Cancer caused by the HPV.

2 doses of flu vaccine needed against bird flu pandemic
An international study led by University of Leicester researchers has determined that vaccination will be the best way to protect people in the event of the next influenza pandemic – but that each person would need two doses.

UN hails recipients of Nobel Prize for discovering HIV
The United Nations has applauded the awarding of the 2008 Nobel Prize for Medicine to two French scientists for their discovery of HIV and for their subsequent pioneering research into the virus.

12 diseases worsened by climate change
Health experts from the Wildlife Conservation Society released a report that lists 12 pathogens that could spread into new regions as a result of climate change, with potential impacts to both human and wildlife health and global economies.

Indian doctors can't deny HIV+, AIDS patients
India's Supreme Court has approved the Indian Govt.'s direction to all States that doctors in government and private hospitals should not refuse treatment to People Living with HIV/AIDS (PLHA).

Childhood wheezing with rhinovirus can increase asthma risk
Infants who experience viral respiratory illnesses with wheezing are known to be at increased risk for developing asthma later during childhood. It is not known, however, whether every type of respiratory virus that produces wheezing presents similar risk.

HIV began spreading among humans between 1884 and 1924
New research indicates that the most pervasive global strain of HIV began spreading among humans between 1884 and 1924, suggesting that growing urbanization in colonial Africa set the stage for the HIV/AIDS pandemic.

Stomach bacteria protect against type 1 diabetes
In a dramatic illustration of the potential for microbes to prevent disease, researchers at Yale University and the University of Chicago showed that mice exposed to common stomach bacteria were protected against the development of Type I diabetes.

QIAGEN's careHPV test provides more accurate screening
A new HPV test developed by QIAGEN specifically for use in regions of the world with scarce resources is "substantially" more accurate in identifying women with cervical disease than the current methods (Pap testing and visual inspection) in these countries.

Two HIV/TB global leaders announce merger talks
Formal merger negotiations were announced between two global leaders on HIV and TB: Health & Development Networks (HDN) and the International HIV/AIDS Alliance - at the XVII International AIDS Conference which concluded in Mexico on 8_August 2008. The merger will create a new joint organisation with a global mandate, which will be part of the Alliance family.

India to develop HIV AIDS vaccine soon
A second Phase I AIDS vaccine clinical trial in India was successfully completed, the Indian Council of Medical Research, the National AIDS Control Organization and the International AIDS Vaccine Initiative announced.

HIV risk high in indian women abused by husbands
Married women in India who experience physical and sexual violence from their husbands have an increased risk of HIV infection, compared with women who are not abused by their husbands, according to a study in the August 13 issue of JAMA, a theme issue on violence and human rights.

Dr. Ramadoss to Mexico to attend AIDS Conference
Indian Health Minister Dr. Anbumani Ramadoss, Minister of Health & Family Welfare, Government of India has left for Mexico city and New York on official tour today.

WHO's new HIV AIDS guide
At the XVII International AIDS Conference in Mexico City, the World Health Organization (WHO) launched a package of priority interventions designed to help low- and middle-income countries move towards universal access to HIV/AIDS prevention, treatment, care and support.

International AIDS Society updates treatment guidelines for HIV infection
An evaluation of recent data has led to an update in the guidelines and recommendations for antiretroviral treatment of adult human immunodeficiency virus (HIV) infection, according to an article in the August 6 issue of JAMA, a theme issue on HIV/AIDS.

40% higher HIV infection estimate in US
The Centers for Disease Control and Prevention (CDC) is expected soon to increase the estimate of new HIV infections in the United States by 40 percent. This highlights the need to make HIV testing a routine part of medical care and provide better funding to care for those who test positive, according to the HIV Medicine Association (HIVMA).

Genetic variation in Africans raises HIV risk
A genetic variation which evolved to protect people of African descent against malaria has now been shown to increase their susceptibility to HIV infection by up to 40 per cent, according to new research. Conversely, the same variation also appears to prolong survival of those infected with HIV by approximately two years.

FDA should take steps to challenge bogus immunity claims
US Center for Science in the Public Interest (CSPI) urges FDA to crack down on food frauds saying that Kraft, General Mills, Dole, & others ripping off consumers with bogus immunity claims.

Cold sore's herpes simplex virus mechanism revealed
Now that Duke University Medical Center scientists have figured out how the virus that causes cold sores hides out, they may have a way to wake it up and kill it.

US Food Protection Plan shows significant progress
The U.S. Food and Drug Administration's Food Protection Plan Progress Report in conjunction with the Interagency Working Group on Import Safety Action Plan Update, shows significant areas of activity to further improve the safety of America's food supply since unveiling its Food Protection Plan in November 2007.

HPV vaccine Cervarix in UK's immunisation programme
The UK's leading cervical cancer charity, Jo's Trust, has welcomed the UK's Department of Health's announcement that the HPV vaccine, Cervarix will be used in the national immunisation programme for 12/13 year olds starting in September, 2008.

Oestrogen makes male organ resistant to HIV
Topical oestrogen applied to the human penis could stop the spread of HIV, revealed by Australian researchers at the University of Melbourne.

Persistent HPV infection raises cervical cancer risk
Persistent infection with human papillomavirus (HPV) could be a useful clinical marker for increased risk of cervical cancer, the second most common cancer in women worldwide, revealed by researchers from the University of North Carolina at Chapel Hill.

OPAL Therapy cost-effective method of treating HIV
Australian researchers have unveiled a new immunotherapy technique to help prevent the progression from HIV infection to AIDS. Details of the simple, cost-effective technique are published May 2nd in the open-access journal PLoS Pathogens.

Mothers less likely to vaccinate daughters against HPV
U.S. mothers report they are less likely to vaccinate daughters under age 13 against human papillomavirus virus (HPV), even though the vaccine is recommended for girls at age 11 and 12, it's incumbent upon the healthcare community to work to improve mom's acceptance of the vaccination for younger daughters, say researchers at Cincinnati Children's Hospital Medical Center who conducted the study.

21% children not fully protected against vaccine-preventable diseases
The U. S. Department of Health and Human Services (HHS) and the Centers for Disease Control and Prevention (CDC) launched National Infant Immunization Week (NIIW) last week.

Monitoring AIDS treatment by physical signs is effective
When millions of HIV-infected people in poor countries began receiving advanced drug therapies, critics worried that patient care would suffer because few high-tech laboratories were available to guide treatments. But according to a study being published in The Lancet, these concerns are as yet unfounded.

New bird flu vaccine may give long-term defense
A new vaccine under development may provide protection against highly pathogenic bird flu and its evolving forms, according to researchers at Purdue University and the Centers for Disease Control and Prevention who discovered the new preventative drug and have tested it in mice.

GSK's new vaccine Rotarix to prevent gastroenteritis by rotavirus
The U.S. Food and Drug Administration announced the approval of Rotarix, the second oral U.S. licensed vaccine for the prevention of rotavirus, an infection that causes gastroenteritis (vomiting and diarrhea) in infants and children. Rotarix is a liquid and given in a two-dose series to infants from 6 to 24 weeks of age.

CD16 monocyte could be a biomarker for progression of HIV
An increase in the CD163+/CD16+ monocyte subset could be a biomarker for the progression of HIV disease, according to researchers at Temple University, reported in the March issue of AIDS Research and Human Retroviruses.

VereFlu portable lab-on-chip for detection of bird flu
Following the success of the evaluation trials conducted at the prestigious National University Hospital of Singapore, Veredus Laboratories and STMicroelectronics (NYSE: STM) announced the commercial availability of VereFlu, a portable lab-on-chip application for rapid detection of all major influenza types at the point of need.

HIV cases reduced in New Zealand
The New Zealand AIDS Foundation is welcoming the reduction in overall numbers of new HIV diagnoses in 2007, in particular that diagnoses among gay and bisexual men have remained equivalent to 2006 levels.

Alarming rates of STDs among teenage girls
A US study found that one in four teenage girls aged 14 to 19 has a sexually transmitted disease (STD). Nearly half the African-Americans in the study were infected by one of the diseases. The survey, part of the National Health and Nutrition Examination Survey, did not ask about syphilis or gonorrhea, so it is likely the STD rates are actually higher.

HIV AIDS organisations to highlight progress and lessons learned
HIV/AIDS implementers from around the world will gather in Kampala, Uganda, from June 3-7 for the 2008 HIV/AIDS Implementers' Meeting. Recognizing the rapid expansion of HIV/AIDS programs worldwide, the focus of this year's meeting is building the capacity of local prevention, treatment, and care programs; enhancing quality; and promoting coordination among partners.

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