Efficacy - most related articles:

- Taranabant for obesity discontinued by Merck - 2.8
- Many new drugs did not have comparative effectiveness information - 2.5
- Pfizer new drug could provide a new treatment option for postmenopausal women - 2.5
- Drug eluting stents prove more effective - 2.3
- Healthy lifestyle is in mind - 2.3
- Alzheimer disease drug enters into phase II III study - 2.2
- Enbrel, etanercept improved psoriasis in children and adolescents - 2.1
- Gardasil efficacious against HPV 16 infection - 2.1
- Pneumococcal vaccine offers protection to HIV infected - 2.1

Efficacy articles

Antibiotics a safe and viable alternative to surgery for uncomplicated appendicitis
Giving antibiotics to patients with acute uncomplicated appendicitis is a safe and viable alternative to surgery, say experts in a study published in BMJ.

CT colonography a front line colorectal cancer screening tool for seniors
Computerized tomographic (CT) colonography (CTC), also known as virtual colonoscopy, is comparable to standard colonoscopy in its ability to accurately detect cancer and precancerous polyps in people ages 65 and older.

Pfizer new drug could provide a new treatment option for postmenopausal women
Pfizer Inc. will announce new one-year results from the Selective estrogens, Menopause, And Response to Therapy [SMART]-5 Phase 3 study of the safety and efficacy of the investigational tissue selective estrogen complex (TSEC) bazedoxifene/conjugated estrogens (BZA/CE) at the 22nd annual meeting of the North American Menopause Society (NAMS), September_21-24 in Washington, D.C.

Copper reduces infection risk by 40%
Copper touch surfaces could have a key role in preventing the transmission of healthcare-associated infections. Extensive laboratory tests have demonstrated copper's antimicrobial efficacy against key organisms. A 97% reduction in surface pathogens in rooms with copper surfaces has been demonstrated.

Lithium may prevent brain damage in patients with Parkinson's disease
Researcher are focusing on lithium as a potential treatment for Parkinson's disease -- PD -- as well as its efficacy in combination with drugs currently used to control the symptoms of the disease. Lithium profoundly prevents the aggregation of toxic proteins and cell loss associated with Parkinson's disease (PD) in a mouse model of the condition.

Niacin and statin treatment did not protect heart
The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped a clinical trial studying a blood lipid treatment 18 months earlier than planned.

Tai chi may improve quality of life in chronic heart failure patients
Tai chi, the ancient Chinese meditative exercise, may improve quality of life, mood and exercise self-efficacy in chronic heart failure patients, according to research led by a team at Beth Israel Deaconess Medical Center.

QNEXA for Weight Loss in obesity - CONQUER study
VIVUS, Inc. (NASDAQ: VVUS) announced that detailed results from the 56-week CONQUER study were published in The Lancet evaluating the efficacy and safety of investigational drug QNEXA in 2,487 patients across 93 sites in the US.

Few questions can determine risk for lung cancer
Aa simple questionnaire designed to identify patients at high risk of lung cancer is found helpful. The new study is featured in the November issue of the Journal of Thoracic Oncology.

Diabetes drug metformin enhances cancer vaccine efficacy
University of Pennsylvania School of Medicine researchers have found that a common anti-diabetic drug might enhance the effectiveness of vaccines. The findings are described this week in an advanced online publication of Nature.

Merck's heart failure drug rolofylline failed
Merck's experimental heart failure drug rolofylline failed to meet the goals in a clinical trial, failing to improve patients. Merck won't seek approval this year for this heart failure drug rolofylline after preliminary results.

Champion clinical trial program of cangrelor discontinued
The Medicines Company (NASDAQ: MDCO) announced that it is discontinuing its Phase 3 CHAMPION clinical trial program of cangrelor in patients undergoing percutaneous coronary intervention (PCI).

Drug eluting stents prove more effective
The Cardiovascular Research Foundation (CRF) announced that its landmark study comparing the safety and efficacy of drug-eluting stents and bare-metal stents was published in The New England Journal of Medicine.

Pediatric vaccine prevents pneumococcal meningitis
A standard pediatric vaccine used to prevent several common types of life-threatening infections also effectively reduced the rates of another disease, pneumococcal meningitis, in children and adults, according to a multi-center study led by the University of Pittsburgh School of Medicine.

Gardasil HPV vaccine prevented genital lesions in men
GARDASIL [Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant], the cervical cancer vaccine from Merck & Co., Inc., prevented 90 percent of external genital lesions caused by human papillomavirus (HPV) types 6, 11, 16 and 18 in a pivotal Phase III study in men aged 16 to 26.

Trials supporting FDA approved drugs remained unpublished
Over half of all supporting trials for FDA-approved drugs remained unpublished 5 years after approval, says new research published in this week's PLoS Medicine. The most important trials determining efficacy, and those with statistically significant results and larger sample sizes, are more likely to be published.

Travelers' diarrhea vaccine skin patch for travelers
Researchers at The University of Texas School of Public Health have found that patients given a travelers' diarrhea vaccine were significantly less likely to suffer from clinically significant diarrhea than those who received placebo, according to a study published in this week's edition of The Lancet.

Novartis' Femara protects against breast cancer return
Women may reduce the risk of their breast cancer returning by starting treatment with Femara (letrozole) anywhere from one to seven years after finishing tamoxifen therapy, according to a new analysis published in the Journal of Clinical Oncology.

NEJM Antidepressant's Publication study may discourage depressed people
Mental Health America notifies the potential harm of the NEJM's Selective Publication of Antidepressant Trials study that it may discourage people with depression from seeking appropriate care and evidence-based treatments that work for them. Mental Health America is one of America's leading mental health advocacy groups.

Exercise improves symptoms in arthritis patients
Patients with arthritis tend to be less fit than their peers who don't have this condition. Studies have shown, however, that they can safely participate in exercise programs to increase their fitness, strength and psychosocial status and that health providers recommend that arthritis patients participate in exercise.

20 Efficacy articles listed above.

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