Patient articles

Chronic fatigue syndrome is not psychological disease
Researchers identified distinct immune changes in patients diagnosed with chronic fatigue syndrome, known medically as myalgic encephalomyelitis (ME/CFS) or systemic exertion intolerance disease.

Aggressive HIV recombinant strain progress to AIDS within 3 years
One recombinant variant observed in patients in Cuba appears to be much more aggressive than other known forms of HIV. Patients progress to AIDS within three years of infection - so rapidly that they may not even realise they were infected.

Paradoxical effect of certain antidepressants discovered
New research helps explain a paradoxical effect of certain antidepressants--that they may actually worsen symptoms before helping patients feel better. These findings may help investigators fix the problem as well as create new classes of drugs to treat depression.

Dr Kent Brantly - Ebola patient released from Emory University Hospital in Atlanta
Dr. Kent Brantly, the Samaritan’s Purse doctor who contracted Ebola while caring for patients in Liberia, was released from Emory University Hospital in Atlanta after completing his recovery from the deadly virus.

Ruxolitinib and tofacitinib restore hair in patients with alopecia areata
Researchers have identified the immune cells responsible for destroying hair follicles in people with alopecia areata, a common autoimmune disease that causes hair loss, and have tested an FDA-approved drug that eliminated these immune cells and restored hair growth in a small number of patients.

COPD patients at higher risk of heart failure
Patients with chronic obstructive pulmonary disease (COPD) have a complication to worry about is heart failure. A new study found the prevalence of heart failure is significantly higher in patients with COPD compared to the rest of the study population. They also found that the risk was especially high among African-American patients with COPD.

Cyramza for stomach cancer approved in US
Cyramza (ramucirumab) is approved to treat patients with advanced stomach cancer or gastroesophageal junction adenocarcinoma, a form of cancer located in the region where the esophagus joins the stomach.

Bevacizumab offers no benefit for glioblastoma
Avastin - bevacizumab failed to increase overall survival (OS) or statistically significant progression-free survival (PFS) for glioblastoma patients in the frontline setting.

Crohn's disease - accelerated step-care a best management practice
The final results from an international clinical trial involving nearly 2,000 patients with Crohn's disease support the use of a new management strategy referred to as accelerated step-care as a best practice for the care of active Crohn's disease.

Heart needs rhythm even before it has blood to pump
To develop correctly, baby hearts need rhythm even before they have blood to pump. “We have discovered that mechanical forces are important when making baby hearts,” said Mary Kathryn Sewell-Loftin, a Vanderbilt graduate student working with a team of Vanderbilt engineers, scientists and clinicians attempting to grow replacement heart valves from a patient’s own cells.

Dexcom's G4 Platinum continuous glucose monitoring system approved for kids
The U.S. Food and Drug Administration today approved the expanded use of the Dexcom G4 Platinum Continuous Monitoring System for patients with diabetes ages 2 to 17 years. The G4 Platinum System, which monitors blood glucose levels in people with diabetes, had been approved for patients ages 18 and older.

Alzheimer's related memory loss linked to Neuroligin-1 protein
Cleveland Clinic researchers have identified a protein in the brain that plays a critical role in the memory loss seen in Alzheimer's patients. The protein – Neuroligin-1 (NLGN1) – is known to be involved in memory formation; this is the first time it's been linked to amyloid-associated memory loss.

Vitamin D reduces multiple sclerosis progression
Vitamin D status appears to be associated with reduced disease activity in patients with multiple sclerosis (MS) and a slower rate of disease progression. MS is a common cause of neurological disability and vitamin D status may be related to the disease process.

Vitamin E may slow functional decline in Alzheimer's Disease patients
A new research suggests that alpha tocepherol, fat-soluble Vitamin E and antioxidant, may slow functional decline (problems with daily activities such as shopping, preparing meals, planning, and traveling) in patients with mild-to-moderate Alzheimer's disease and decrease caregiver burden.

Computer algorithm may predict breast cancer type
Researchers have created a computer algorithm that successfully predicts whether estrogen is sending signals to cancer cells to grow into tumours in the breast. By finding this hormone receptor, known as estrogen receptor positive, physicians can prescribe anti-estrogen drug therapies, improving patient outcomes.

High salt in some medicines may increase heart attack and stroke risk
Taking the maximum daily dose of some medicines would exceed the recommended daily limits for sodium, without any additional dietary intake. Public should be warned about the potential dangers of high sodium intake from prescribed medicines, reveals new study.

Mitral valve replacement may be more effective than mitral valve repair
The Cardiothoracic Surgical Trials Network (CTSN), whose Data and Clinical Coordinating Center is at Icahn School of Medicine at Mount Sinai, is reporting for the first time evidence on whether or not there is any significant difference between the two current surgical approaches to treat patients with severe ischemic mitral regurgitation -- mitral valve repair and mitral valve replacement.

SMS reminders about heart medication improved patient adherence
Getting reminder texts helped patients take their heart medicines (anti-platelet and cholesterol-lowering drugs) more regularly, according to research presented at the American Heart Association's Scientific Sessions 2013.

Drug shortages to be solved in US says FDA
US FDA is taking two actions to further enhance the agency's ongoing efforts to prevent and resolve drug shortages, a significant public health threat that can delay, and in some cases even deny, critical care for patients.

DNA markers in low IQ autism suggest heredity - ASD
Researchers are striving to understand the different genetic structures that underlie at least a subset of autism spectrum disorders. In cases where the genetic code is in error, did that happen anew in the patient, perhaps through mutation or copying error, or was it inherited? A new study in the American Journal of Human Genetics finds evidence that there may often be a recessive, inherited genetic contribution in autism with significant intellectual disability.

Prostate cancer - active surveillance and watchful waiting better
Many men with low-risk, localized prostate cancers can safely choose active surveillance or "watchful waiting" instead of undergoing immediate treatment and have better quality of life while reducing health care costs, according to a study by researchers at Dana-Farber Cancer Institute and Massachusetts General Hospital.

Tamiflu drug resistance in H7N9 flu cases raises concern
Resistance easily develops when patients take antiviral drugs such as oseltamivir (tamiflu) for treating h7n9 influenza infections. Researcher's analysis, which includes 14 patients who were hospitalized in Shanghai within 2 days of starting therapy with Tamiflu, appears in The Lancet.

Cancer patients vulnerable to financial stress and bankruptcy
People diagnosed with cancer are more than two-and-a-half times more likely to declare bankruptcy than those without cancer. Younger cancer patients had two- to five-fold higher bankruptcy rates compared to older patients, and that overall bankruptcy filings increased as time passed following diagnosis.

New genomic prostate cancer test improves risk assessment and surveillance
A new genomic test for prostate cancer can help predict whether men are more likely to harbor an aggressive form of the disease, according to a new UC San Francisco study. The test, which improves risk assessment when patients are first diagnosed, can also aid in determining which men are suitable for active surveillance – a way of managing the disease without direct treatment.

Fun friends social relationships influence quality of life in breast cancer patients
Breast cancer patients who say they have people with whom they have a good time, or have "positive social interactions" with, are better able to deal with pain and other physical symptoms. This study provides research-based evidence that social support helps with physical symptoms.

Medical interns spend little time at patient bedside
Medical interns spend just 12 percent of their time examining and talking with patients, and more than 40 percent of their time behind a computer, according to a new Johns Hopkins study that closely followed first-year residents at Baltimore's two large academic medical centers.

H7N9 bird flu in China - 104 cases
Chinese National Health and Family Planning Commission notified WHO of an additional two laboratory-confirmed cases of human infection with avian influenza A(H7N9) virus. Both the patients are reported from Zhejiang province.

Propranolol may improve working memory in autism patients
People with an Autism Spectrum Disorder (ASD) often have trouble communicating and interacting with others because they process language, facial expressions and social cues differently. Previously, researchers found that propranolol, a drug commonly used to treat high blood pressure, anxiety and panic, could improve the language abilities and social functioning of people with an ASD. Now, University of Missouri investigators say the prescription drug also could help improve the working memory abilities of individuals with autism.

8 of 29 in critical condition - Boston Marathon explosion
The MGH has seen 29 patients related to the Boston Marathon explosion today. Eight of the 29 are in critical condition. None of the patients are pediatric (18 and younger). The injuries range from cuts and bruises to amputations.

Skin cells can be morphed into brain cells in multiple sclerosis & cerebral palsy patients
Researchers at Case Western Reserve School of Medicine have discovered a technique that directly converts skin cells to the type of brain cells destroyed in patients with multiple sclerosis, cerebral palsy and other so-called myelin disorders.

Lymphoseek to locate lymph nodes in breast cancer or melanoma patients
The U.S. Food and Drug Administration approved Lymphoseek (technetium Tc 99m tilmanocept) Injection, a radioactive diagnostic imaging agent that helps doctors locate lymph nodes in patients with breast cancer or melanoma who are undergoing surgery to remove tumor-draining lymph nodes.

Heart disease risk smaller after breast cancer radiotherapy
Researchers have for the first time calculated by how much radiotherapy for breast cancer increases the risk of heart disease and the findings can now be used by doctors to help treat patients more appropriately.

Buphenyl a possible drug for Alzheimer's disease
Buphenyl, an FDA-approved medication for hyperammonemia, may protect memory and prevent the progression of Alzheimer's disease. Hyperammonemia is a life-threatening condition that can affect patients at any age. It is caused by abnormal, high levels of ammonia in the blood.

Inflammatory disease therapies do not increase shingles risk
Although patients with rheumatoid arthritis (RA) have a disproportionately higher incidence of herpes zoster (shingles), an analysis that included nearly 60,000 patients with RA and other inflammatory diseases found that those who initiated anti-tumor necrosis factor therapies were not at higher risk of herpes zoster compared with patients who initiated nonbiologic treatment regimens.

DNA strands can predict life expectancy and survival in patients
Can the length of strands of DNA in patients with heart disease predict their life expectancy? Researchers from the Intermountain Heart Institute at Intermountain Medical Center in Salt Lake City, who studied the DNA of more that 3,500 patients with heart disease, say yes it can.

Early detection of PML improves survival of multiple sclerosis patients
The drug natalizumab is effective for treating multiple sclerosis (MS), but it increases the risk of a rare but potentially fatal brain infection called progressive multifocal leukoencephalopathy (PML). The study suggests that early detection of PML may help improve survival and disability levels.

Darbepoetin alfa does not improve health of anemic heart failure patients
Researchers from Cleveland Clinic and Sweden-based Sahlgrenska University Hospital have found that a commonly used drug to treat anemia in heart failure patients – darbepoetin alfa – does not improve patients' health, nor does it reduce their risk of death from heart failure.

Weight loss may prevent and treat osteoarthritis in obese
Weight loss may prevent and significantly alleviate the symptoms of osteoarthritis, a progressive disease of the joints known as "wear and tear" arthritis. Obesity actually may trigger the biomechanical and inflammatory changes that cause osteoarthritis, and the pain and loss of mobility associated with the condition.

Surgical mask on flu patients can reduce spread of infectious virus
People may more likely be exposed to the flu through airborne virus than previously thought, according to new research from the University of Maryland School of Public Health. The study also found that when flu patients wear a surgical mask, the release of virus in even the smallest airborne droplets can be significantly reduced.

Medicare hospice benefit - better care at a lower cost
Medicare patients who enrolled in hospice received better care at a significantly lower cost to the government than those who did not use the Medicare hospice benefit. The data indicate that annual savings to Medicare could amount to $2.4 million to $6.4 million.

Anemia drug Omontys recalled due to anaphylaxis
In US, Omontys Injection is recalled due to reports of anaphylaxis, a serious and life-threatening allergic reaction. Omontys is used to treat anemia in adult dialysis patients. Until further notice, health care providers should stop using Omontys.

Kadcyla - new treatment for late stage HER2 breast cancer
Kadcyla (ado-trastuzumab emtansine) - a new therapy for patients with HER2-positive, late-stage (metastatic) breast cancer is approved by US FDA. Breast cancer is the second leading cause of cancer-related death among women. Almost 20 percent of breast cancers have increased amounts of the HER2 protein.

Delivery of drug tPA directly into brain helps stroke patients
In an update to previous research, Johns Hopkins neurologists say minimally invasive delivery of the drug tPA directly into potentially lethal blood clots in the brain helped more patients function independently a year after suffering an intracerebral hemorrhage (ICH), a deadly and debilitating form of stroke.

Kynamro approved to treat inherited cholesterol disorder
Kynamro - mipomersen sodium - injection approved as an addition to lipid-lowering medications and diet to treat patients with a rare type of high cholesterol called homozygous familial hypercholesterolemia (HoFH). Kynamro is approved by the U.S. Food and Drug Administration.

Intermittent dosing with vemurafenib may prolong lives of melanoma patients
Researchers in California and Switzerland have discovered that melanomas that develop resistance to the anti-cancer drug vemurafenib (marketed as Zelboraf), also develop addiction to the drug, an observation that may have important implications for the lives of patients with late-stage disease.

Fulyzaq - first anti diarrheal drug for HIV AIDS patients
The U.S. Food and Drug Administration approved Fulyzaq (crofelemer) to relieve symptoms of diarrhea in HIV/AIDS patients taking antiretroviral therapy, a combination of medicines used to treat HIV infection.

CBT helps depressive patients on antidepressants
Depression is predicted to become the leading cause of disability in high income countries by 2030, and currently only a third of patients with depression respond fully to antidepressant medication.

Alzheimer disease drug enters into phase II III study
Although several pharmaceutical companies in US have experienced setbacks with Alzheimer's compounds, Merck & Co., Inc. hopes to defy the odds with plans to take a Alzheimer pill into a Phase II/III clinical study with patients who suffer from mild-to-moderate stages of the Alzheimer's disease.

NYU Langone Medical Center and Hurricane Sandy impact
After the onslaught of superstorm Sandy caused the back-up generator at New York University's medical center to fail, hospital officials say at least 300 patients were successfully evacuated to other area hospitals overnight.

What role genes play in treating TB
The University of Liverpool has been awarded funding to determine whether differences in our genes determine how patients respond to drugs used to treat Tuberculosis (TB) in Sub-Saharan Africa.

Fungal meningitis outbreak in US due to NECC epidural steroid injection
A multistate outbreak of fungal meningitis among patients who received an epidural steroid injection with a potentially contaminated product has been notified in USA. The Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) are currently coordinating the investigation of this outbreak of fungal meningitis.

Electronic health records improve patient care quality
A new study provides compelling evidence that electronic health records (EHRs) enhance the quality of patient care in a community-based setting with multiple payers, which is representative of how medicine is generally practiced across the United States.

Secondary osteoporosis - treat the cause of osteoporosis first
An SGH study has revealed that considering all osteoporotic patients as having simple osteoporosis and treating all of them alike by putting them on potent long term medication without finding out the cause of their osteoporosis may be ineffective and in most cases downright harmful.

Blood test may detect aggressive prostate cancer
Scientists have developed a test that studies genetic patterns in blood cells to detect advanced?stage prostate cancer. The study shows that gene patterns in blood cells act as a barcode and could be used together with the current PSA test to select those patients with the worst prognosis in need of immediate treatment.

Pacemaker could help more heart failure patients
A new study from Karolinska Institutet demonstrates that a change in the ECG wave called the QRS prolongation is associated with a higher rate of heart-failure mortality. According to the team that carried out the study suggests that more heart failure cases could be helped by pacemakers.

Online access to doctors notes improves patient care
Patients who have access to doctor's notes in their medical records are more likely to understand their health issues, recall what the doctor told them and take their medications as prescribed, according to a study.

Breast cancer can be detected by a simple blood test
A simple blood test could one day be a more accurate way to test for the early signs of breast cancer than using mammograms to spot a lump. Researchers reveals that the blood test could improve treatment by detecting whether breast cancer patients are likely to relapse and what drugs their particular type of tumour will respond to.

Exercise improves memory and thinking after stroke
Just six months of exercise can improve memory, language, thinking and judgment problems by almost 50 per cent. Toronto researchers found that the proportion of stroke patients with at least mild cognitive impairment dropped from 66 per cent to 37 per cent during a research study on the impact of exercise on the brain.

RYGB gastric bypass surgery improves heart risk factors
Severely obese patients who had Roux-en-Y gastric bypass surgery had significant weight loss that was sustained for an average of 6 years after the surgery and also experienced frequent remission and lower incidence of diabetes, hypertension, and abnormal cholesterol levels, compared to participants who did not have the surgery.

Acupuncture may be better for chronic pain
An analysis of patient data from 29 randomized controlled trials suggests that acupuncture may be better than no acupuncture or sham acupuncture for the treatment of some chronic pain.

Stribild once a day combination pill to treat HIV
Stribild (elvitegravir, cobicistat, emtricitabine, tenofovir disoproxil fumarate), a new once-a-day combination pill to treat HIV-1 infection in adults who have never been treated for HIV infection, is approved in US by FDA.

Stenting early better than medical therapy alone
For patients with stable coronary artery disease who have at least one narrowed blood vessel that compromises flow to the heart, medical therapy alone leads to a significantly higher risk of hospitalization and the urgent need for a coronary stent when compared with therapy that also includes initial placement of artery-opening stents.

Chemotherapy resistance develops due to WNT in cancer patients
Developing resistance to chemotherapy is a nearly universal, ultimately lethal consequence for cancer patients with solid tumors ? such as those of the breast, prostate, lung and colon ? that have metastasized, or spread, throughout the body.

Heart failure depression symptoms reduced by exercise
Moderate exercise helps ease depression in patients with chronic heart failure, and is also associated with a small but significant reduction in deaths and hospitalizations.

Drug resistant HIV increasing - Africa
Lancet reported in a new study that Drug-resistant HIV has been increasing in parts of sub-Saharan Africa over the last decade. Drug resistance could build up if people fail to stick to drug regimes.

Quality of life at end of life for patients with cancer
Better quality of life at the end of life for patients with advanced cancer was associated with avoiding hospitalizations and the intensive care unit, worrying less, praying or meditating, being visited by a pastor in a hospital or clinic, and having a therapeutic alliance with their physician.

Obesity screening recommended for all adults
In an update to its 2003 recommendation statement on screening for obesity in adults, the United States Preventive Services Task Force recommends screening all adult patients for obesity. Screening includes measurement of height and weight to ascertain BMI, although measuring waist circumference also is an accepted method.

US government paying separate managed care programs for same patients
An analysis that included 1.2 million veterans enrolled in the Veterans Affairs health care system and Medicare Advantage plan finds that the federal government spends a substantial and increasing amount of potentially duplicative funds in these separate managed care programs for the care of same individuals.

Alcohol abuse increases after bariatric surgery
Among patients who underwent bariatric surgery, there was a higher prevalence of alcohol use disorders in the second year after surgery, and specifically after Roux-en-Y gastric bypass, compared with the years immediately before and following surgery.

Smoking linked to increased mortality in older patients
An analysis of available medical literature suggests smoking was linked to increased mortality in older patients and that smoking cessation was associated with reduced mortality at an older age, according to a report published in the Archives of Internal Medicine, USA. Smoking is a known risk factor for many chronic diseases, including cardiovascular disease and cancer, however, the epidemiological evidence mostly relies on studies conducted among middle-aged adults.

No heart attacks, strokes or cancer risk from long term insulin use in diabetes patients
Researchers at McMaster University have discovered that long-term insulin use does not harm people with diabetes or pre-diabetes or put them at risk of heart attacks, strokes or cancer. This is contrary to concerns that long-term use of insulin may cause heart disease, says Dr. Hertzel Gerstein, principal investigator of the study.

NASA developed osteoporosis test to detect bone loss early
A more sensitive technique is developed by scientists at Arizona State University and NASA for detecting bone loss early than the X-ray method used today, with less risk to patients.

Largest human cancer genome data released in US
A comprehensive human cancer genome data is released in US for free access by the global scientific community. The amount of information released more than doubles the volume of high-coverage, whole genome data currently available from all human genome sources combined.

Acupuncture improved dyspnea in patients with COPD
Acupuncture appears to be associated with improvement of dyspnea (labored breathing) on exertion, in patients with chronic obstructive pulmonary disease (COPD) revealed by researchers in a new study. The management of dyspnea is an important target in the treatment of COPD, a common respiratory disease characterized by irreversible airflow limitation. COPD is predicted to be the third leading cause of death worldwide by 2020.

Stroke risk greater for older women with atrial fibrillation
In a study that examined use of the anticoagulant medication warfarin and risk of stroke following a diagnosis of atrial fibrillation in older patients, women, especially those 75 years or older, had a higher risk of stroke than men, regardless of their risk profile and use of warfarin, suggesting that current anticoagulant therapy to prevent stroke might not be sufficient for older women.

Chronic migraine and daily headaches patients get little benefit from botox injections
Although botulinum toxin A ("Botox") injections are U.S. Food and Drug Administration approved for preventive treatment for chronic migraines, a review and analysis of previous studies finds a small to modest benefit for patients with chronic migraine headaches and chronic daily headaches, although botox injections were not associated with greater benefit than placebo for preventing episodic migraine or chronic tension-type headaches.

One kidney transplanted 2 times in 2 weeks
For the first time, a kidney that had been donated to a patient in need was removed and implanted into a new patient, the third individual to have the organ, after it failed in the first transplant recipient.

Brain cancer vaccine prepared from brain tumor proves effective
A new brain cancer vaccine tailored to individual patients by using material from their own tumors has proven effective in a multicenter phase 2 clinical trial at extending their lives by several months or longer. The patients suffered from recurrent glioblastoma multiforme-which kills thousands of Americans every year.

Heart failure patients may get benefit from testosterone supplements
Testosterone supplements helped heart failure patients breathe better and exercise more. This new research analyzed four randomized clinical trials of patients with moderate to severe chronic heart failure. Patients were given commercial testosterone supplements by injection, patch or gel.

Bevacizumab with chemotherapy provides no survival benefit for lung cancer patients
Adding the drug bevacizumab (Avastin) to the standard chemotherapy regimen for non-small cell lung cancer (NSCLC) ? an approach approved by the FDA in 2006 ? did not lead to significantly increase survival rates for patients over the age of 65 enrolled in Medicare.

Bariatric surgery better for obese with type 2 diabetes
A study comparing a bariatric surgical procedure with conventional medical treatment in morbidly obese patients with type 2 diabetes mellitus suggests that surgery was associated with remission or improvement in diabetes-related outcomes.

Depression - now blood test can diagnose depression in teens
A breakthrough approach that allows an objective diagnosis of major depression in teens by measuring a specific set of genetic markers found in a patient's blood. The current method of diagnosing depression is subjective. It relies on the patient's ability to recount his symptoms and the physician's ability and training to interpret them.

Whole genome breast cancer study launched by Mayo Clinic USA
The Breast Cancer Genome Guided Therapy Study (BEAUTY Project) will help physicians tailor chemotherapy to breast cancer patients based on their individual genomes and the genomes of their tumors.

Antibiotics a safe and viable alternative to surgery for uncomplicated appendicitis
Giving antibiotics to patients with acute uncomplicated appendicitis is a safe and viable alternative to surgery, say experts in a study published in BMJ.

Cancer treatment with personalised approach to cancer patients
Recently researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. They uncovered hundreds of associations between mutations in cancer genes and sensitivity to anticancer drugs.

Bariatric surgery improves and reverses diabetes
Overweight, diabetic patients who underwent bariatric surgery achieved significant improvement or remission of their diabetes.In a randomized, controlled trial, some weight loss surgery patients achieved normal blood sugar levels without use of any diabetes medications.

Alzheimer's Disease patients may not get benefit from antioxidants
An antioxidant combination of vitamin E, vitamin C and a-lipoic acid (E/C/ALA) was not associated with changes in some cerebrospinal fluid biomarkers related to Alzheimer disease in a randomized controlled trial, revealed by researchers.

iPads increase doctors efficiency in healthcare
Providing personal mobile computers like iPads to medical residents increases their efficiency, reduces delays in patient care and enhances continuity of care.

Statin use reduces Parkinson Disease risk
Regular use of cholesterol-lowering statin drugs may be associated with a modest reduction in risk for developing Parkinson disease, particularly among younger patients. Statins are one of the most prescribed classes of drugs in the United States.

Reversing Alzheimer's gene blockade can restore memory
MIT neuroscientists have shown that an enzyme overproduced in the brains of Alzheimer's patients creates a blockade that shuts off genes necessary to form new memories. Furthermore, by inhibiting that enzyme in mice, the researchers were able to reverse Alzheimer's symptoms.

Specific antipsychotic drugs increase risk in elderly dementia patients
Nursing home residents over the age of 65 who take certain antipsychotic medication for dementia are at an increased risk of death, suggests a research paper published in BMJ. Haloperidol had double the risk of mortality amongst other drugs for the condition, say researchers.

New melanoma drug doubles survival of skin cancer patients
Investigators from Vanderbilt-Ingram Cancer Center (VICC) and 12 other centers in the United States and Australia have found that a new drug for patients with metastatic melanoma nearly doubled median overall survival.

Evaluating impact of EHR on childhood obesity
Electronic health records and embedded tools can alert and direct pediatricians so they can better manage the weight of children and teenagers. Researchers analyzed visits for nearly 740,000 children and adolescents ages 2 to 17 to evaluate the impact of computer-assisted decision tools.

Emergency department visita are lower among most satisfied patients
Higher patient satisfaction appears to be associated with lower odds of emergency department use, higher odds for inpatient hospitalization, greater health care and prescription expenditures, and higher mortality risk.

No benefits with B vitamin, omega-3 supplements on cancer outcomes
Taking supplements of B vitamins and omega-3 fatty acids for cancer prevention does not appear to be beneficial for patients with prior cardiovascular disease. Proper nutrition is considered to be protective against cancer but much is unknown about the roles of individual nutrients in different populations.

Vitamin D therapy does not improve heart disease risk
Patients with chronic kidney disease who received the vitamin D compound paricalcitol for up to 48 weeks did not show improvement on measures of cardiac structure, function, or left ventricular mass, compared to patients who received placebo.

Antibiotic amoxicillin no cure for acute sinusitis
Treatment with the antibiotic amoxicillin for patients with acute uncomplicated rhinosinusitis (inflammation of the nasal cavity and sinuses) did not result in a significant difference in symptoms compared to patients who received placebo.

Postoperative radiotherapy does not improve survival in lung cancer patients
Post-operative radiation therapy (PORT), a controversial yet frequently administered treatment for lung cancer, may not prolong life in older people with locally advanced disease.

Additional breast surgery common after partial mastectomy
Nearly one in four women who undergo a partial mastectomy for treatment of breast cancer have another surgery to remove additional tissue (reexcision), and there is substantial surgeon and institutional variation in the rate of reexcisions that cannot be explained by patients' clinical characteristics.

Erivedge approved for skin cancer metastatic basal cell carcinoma
Erivedge or vismodegib was approved by the U.S. Food and Drug Administration to treat adult patients with basal cell carcinoma, the most common type of skin cancer. The Erivedge drug is intended for use in patients with locally advanced basal cell cancer who are not candidates for surgery or radiation and for patients whose cancer has spread to other parts of the body (metastatic).

Regorafenib improves survival of colorectal cancer patients
Regorafenib - an investigational drug - slowed the progression of tumors and lengthened the lives of patients with metastatic colorectal cancer. This is the first novel agent in eight years to show improvement in overall survival of colon cancer patients who have run out of treatment options.

Totally drug resistant tuberculosis TDR TB reported in India
For the first time in India, 12 people have been detected with totally drug-resistant lung tuberculosis (TDR-TB), a condition in which patients do not respond to any TB medication and for which the mortality rate is 100 percent.

Anticoagulant Dabigatran linked to heart attack or MI
The anticoagulant dabigatran is associated with an increased risk of myocardial infarction (heart attack) or acute coronary syndrome in a broad spectrum of patients when tested against some other medicines.

Magnetic stimulation of brain may help stroke patients recover
Imagine waking up and being unable to see or recognize anything on the left side of your body. This condition, called hemispatial neglect, is common after a stroke that occurs on the right side of the brain.

Cholesterol lowering drugs statins may help hospitalized influenza patients
The two main ways to prevent and control influenza today are annual immunization and antiviral drugs. A team of investigators has found that statins, cholesterol-lowering drugs, may offer an additional treatment to complement these approaches and reduce mortality among patients hospitalized with influenza.

Cognitive decline linked to brain volume decreases in parkinson's disease patients
Patients with Parkinson disease-related dementia appear to have increased brain atrophy in the hippocampal, temporal and parietal lobes and decreased prefrontal cortex volume compared to patients with Parkinson disease without dementia.

Cancer screening in older adults appears common, US
A high percentage of adults age 75 years and older continue to report receiving cancer screenings, despite U.S. Preventive Services Task Force guidelines recommending against routine screening for breast, cervical, colorectal and prostate cancer for patients age 75 years and older.

HER growth proteins do not predict outcome of herceptin treatment breast cancer patients
Precisely quantifying the amount of three different HER growth proteins, along with several other proteins believed linked to breast cancer, did not predict a patient's outcome after treatment for HER2 Positive Breast Cancer with Herceptin, say Mayo Clinic researchers.

10% of ADHD patients linked to GMR gene variants
Pediatric researchers analyzing genetic influences in attention-deficit/hyperactivity disorder (ADHD) have found alterations in specific genes involved in important brain signaling pathways.

30% of health spending yield no benefit to patients
House Democratic Caucus Chairman John B. Larson (CT) released the following statement on the resignation of Dr. Donald Berwick as Administrator of the Center for Medicare and Medicaid Services.

Low calorie diet improves heart function in diabetic obese patients
A low-calorie diet eliminates insulin dependence and leads to improved heart function in obese patients with type 2 diabetes. It is striking to see how a relatively simple intervention of a very low calorie diet effectively cures type 2 diabetes mellitus. Moreover, these effects are long term.

4 drugs accounted for two thirds of emergency hospitalizations in US
Handful of drugs are responsible for most emergency room visits by patients in US, revealed by CDC researchers (US Centers for Disease Control and Prevention) in a recent study.

Thin underweight people with lower BMI may have higher post surgical risk
Body Mass Index (BMI) appears to be associated with 30-day mortality risk following surgical procedures, and patients with a BMI of less than 23.1 appear to be at highest risk of death.

Stent design may put patients at risk of heart attack
Stent shortening - a newly observed deformity in cases using a particular family of stents, can cause serious complications for patients, says researchers. In this case the stent clotted off and the patient had a heart attack.

Eylea approved for AMD eye disorder in older people
The U.S. Food and Drug Administration approved Eylea (aflibercept) to treat patients with wet (neovascular) age-related macular degeneration (AMD), a leading cause of vision loss and blindness in Americans ages 60 and older.

Financial reimbursement increases cardiac stress tests in patients
Financial reimbursement and ownership of cardiac imaging equipment appears to influence physicians' use of cardiac stress testing. The study finds that doctors who are reimbursed for both performing the test using their equipment and then interpreting the results were 50 to 100 percent more likely to order cardiac imaging tests on their patients than those who don't bill the fees.

Transcatheter aortic valve replacement TAVR shows superiority in heart patients
A two-year study of patients in the landmark PARTNER trial, which compared transcatheter aortic valve replacement (TAVR) in patients who have severe aortic stenosis and are not candidates for open heart surgery, confirm the one-year findings and support the role of TAVR as the standard of care.

35 new drugs approved in 2011 in US
Over the past 12 months, the U.S. Food and Drug Administration approved 35 new medicines for patients, like two new treatments for hepatitis C; a drug for late-stage prostate cancer; the first new drug for Hodgkin's lymphoma in 30 years; and the first new drug for lupus in 50 years.

7% breast cancer patients have breast reconstruction surgery
Breast reconstruction surgery has a very positive effort on women with breast cancer as they go through their breast cancer journey. Only 7% of female breast cancer patients opt for breast reconstruction surgery.

More aggressive treatment not necessary for men with a family history of prostate cancer
Approximately 10-20 percent of prostate cancer patients have a family history of the disease. There are three major factors that are used to evaluate the extent and aggressiveness of prostate cancer, help make treatment decisions, and estimate prognosis: the Prostate Specific Antigen Level (PSA), Gleason score (GS) from the biopsy, and the digital rectal exam findings (DRE).

Neural stem cell transplant may cure diabetes
Researchers in Japan have discovered how a patient's neural stem cells could be used as an alternative source of the beta cells needed for a regenerative treatment for diabetes.

Medicare patients lead to long term institutionalization in a nursing home
Confirming many elderly patients' worst fears, a national study has shown that being hospitalized for an acute event, such as a stroke or hip fracture, can lead to long-term institutionalization in a nursing home.

Blood test may detect Alzheimer's Disease progression
Researchers found a way to predict how quickly patients with Alzheimer's disease (AD) will lose cognitive function by looking at ratios of two fatty compounds in their blood.

Novartis drug Afinitor everolimus helps advanced breast cancer women
A pivotal Phase III study shows Afinitor (everolimus) tablets plus exemestane, a hormonal therapy, more than doubled the time women lived without tumor growth (progression-free survival; PFS) and significantly reduced the risk of cancer progression by 57% versus exemestane alone in patients with advanced breast cancer.

$3.5 million Komen award to study rare and aggressive type of breast cancer
The Translational Genomics Research Institute (TGen) is part of a team of medical investigators receiving a $3.5 million grant from Susan G. Komen for the Cure to study triple-negative breast cancer, a highly aggressive form of this cancer that disproportionately affects African-Americans.

Alpharadin improved survival in advanced prostate cancer patients
Until recently, options for patients with bone metastases from advanced prostate cancer have been very limited. But now the first Phase III study of an alpha-pharmaceutical in these patients has shown that it can prolong survival significantly, according to research reported recently at the 2011 European Multidisciplinary Cancer Congress.

Local biosurveillance data can improve individual patient care
By taking local biosurveillance data into account when assessing patients for communicable diseases, doctors may be able to make better diagnostic decisions, according to researchers at Children's Hospital Boston. For instance, in the case of strep throat, awareness of local epidemiology at the time of diagnosis could help more than 166,000 people avoid unnecessary antibiotic treatment in the United States every year and catch more than 62,000 missed cases.

Do not eat Rocky Ford Cantaloupe shipped by Jensen Farms US
US FDA is warning consumers not to eat Rocky Ford Cantaloupe shipped by Jensen Farms of Granada, Colo. The majority of the patients reported eating cantaloupe marketed from the Rocky Ford growing region. FDA's traceback data from the State of Colorado about their confirmed cases of Listeria monocytogenes have identified a common producer of Rocky Ford cantaloupes. That producer is Jensen Farms. Although the investigation is ongoing, no other Rocky Ford cantaloupe producer has been found in common in the Colorado traceback.

Drug resistance TB cases rising in Europe
Nobody in Europe is 100 percent protected from drug-resistant tuberculosis, said Ogtay Gozalov, a medical officer at the World Health Organization.

Stroke clinical trial finds intensive medical treatment better than brain stent
Patients at a high risk for a second stroke who received intensive medical treatment had fewer strokes and deaths than patients who received a brain stent in addition to the medical treatment, a large nationwide clinical trial has shown.

New guideline on treatment of high blood pressure
High blood pressure patients should have the diagnosis confirmed at home, according to new guidelines. The way blood pressure is diagnosed and treated is set to be revolutionised following new guidelines for the medical profession issued by NICE and developed in conjunction with the British Hypertension Society (BHS).

Door-to-balloon time is 90 min in 91% of heart attack patients in US
The period from hospital arrival to angioplasty is called "door-to-balloon" time (D2B). A new study showed that 91 percent of patients were treated in a D2B time of less than 90 minutes in 2010, compared with 44 percent in 2005.

Zelboraf approved for late stage skin cancer
The U.S. Food and Drug Administration recently approved Zelboraf (vemurafenib), a drug to treat patients with late-stage (metastatic) or unresectable (cannot be removed by surgery) melanoma, the most dangerous type of skin cancer.

Reducing drug funding to Medicare patients raises questions
The lack of financial assistance to cover the cost of drugs to Medicare beneficiaries could result in an additional 18,000 patients discontinuing one or more prescriptions for essential drugs a year and others to not take their required medications regularly.

Rivaroxaban can prevent strokes in atrial fibrillation patients
Rivaroxaban, an anti-clotting drug, was shown to be an attractive alternative to warfarin in the prevention of stroke in patients with atrial fibrillation, revealed by researchers recently.

Allergan's BOTOX will be available in European Countries for Urinary Incontinence
Allergan is pleased to announce that BOTOX (botulinum toxin type A) has received a positive opinion from the Irish Medicines Board for the management of urinary incontinence in adults with neurogenic detrusor overactivity (NDO) resulting from neurogenic bladder due to stable sub-cervical spinal cord injury, or multiple sclerosis.

New urine test can detect prostate cancer risk early
A new urine test can help aid early detection of and treatment decisions about prostate cancer. Examining the urine sample for TMPRSS2:ERG and PCA3 and stratified patient into low, intermediate and high score, indicating their risk of cancer can help.

mChip can revolutionize medical care around the world
New low-cost diagnostics like the mChip can revolutionize medical care around the world, revealed by researcher in US. Microfluidics-the manipulation of small amounts of fluids-and nanoparticles can be successfully leveraged to produce a functional low-cost diagnostic device in extreme resource-limited settings.

Genetic changes may lead to Barrett's esophagus and esophageal cancer
Mutations in three genes have been identified that are more prevalent in patients with esophageal cancer and Barrett esophagus, a premalignant metaplasia (change in cells or tissue) caused by chronic gastroesophageal reflux disease (GERD), according to preliminary research reported in the July 27 issue of JAMA.

MS drugs help, but come at high cost
Multiple sclerosis drugs used to slow down the multiple sclerosis progression may help some patients, but at a very high cost. These disease modifying drugs ? come at a very high cost when compared to therapies that address the symptoms of MS and treatments for other chronic diseases.

FDA panel votes to revoke approval for Avastin for advanced breast cancer
The Oncologic Drugs Advisory Committee, FDA, USA disapproved the Avastin which cited a lack of survival benefit. Now as two more trials have been analyzed -- neither showing a survival benefit -- the FDA stated that in the balance, the benefit did not outweigh the harm.

Abatacept and GAD-alum to slow progression of type 1 diabetes
Abatacept (Orencia), an immune system modulator and GAD-alum, an antigen based therapy found beneficial for patients with type 1 diabetes. TrialNet researchers are conducting a series of studies to test ways to prevent or delay progression of type 1 diabetes. Results of two studies testing drugs to slow or stop the immune system's attack on insulin-producing cells in people newly diagnosed with type 1 diabetes will be presented at the American Diabetes Association's (ADA) 71st Scientific Sessions in San Diego and simultaneously published online in the Lancet.

Physicians accepting fewer patients with health insurance
There is a drop in physicians' acceptance of health insured patients in past years in US. As a result, insured patients could face new obstacles to receiving the medical attention they need, and overall access to health care could actually contract. As required under the Patient Protection and Affordable Care Act of 2010, millions of people will soon be added to the ranks of the insured. However, this rapid expansion of coverage is colliding with a different, potentially problematic trend that could end up hampering access to health care.

Many advanced breast cancer patients do not receive recommended treatment
Forty-five percent of women with advanced breast cancer in the U.S. did not receive postmastectomy radiation therapy (PMRT) despite the publication of evidence-based guidelines outlining PMRT as a potentially lifesaving treatment, according to new research from The University of Texas MD Anderson Cancer Center. The study, published in the July issue of Cancer, found that PMRT use rates for women with advanced breast cancer have remained static since 1999.

HIV drugs may cause premature aging
Researchers revealed that a class of anti-retroviral drugs (NRTIs) commonly used to treat HIV can cause premature ageing, as the drugs damage DNA in the patient's mitochondria. HIV-infected people treated with antiretroviral drugs sometimes show advanced signs of frailty and age-associated diseases such as cardiovascular disease and dementia at an early age.

Lithium may prevent brain damage in patients with Parkinson's disease
Researcher are focusing on lithium as a potential treatment for Parkinson's disease -- PD -- as well as its efficacy in combination with drugs currently used to control the symptoms of the disease. Lithium profoundly prevents the aggregation of toxic proteins and cell loss associated with Parkinson's disease (PD) in a mouse model of the condition.

Motivational interviews reduce depression, increase survival after stroke
Researchers revealed that patients who received several sessions of a "motivational interview" early after a stroke had normal mood, fewer instances of depression and greater survival rates at one year compared to patients who received standard stroke care.

Rheumatoid arthritis and psoriasis medications lowers diabetes risk
Certain rheumatoid arthritis and psoriasis medications are associated with reduced diabetes risk, revealed by researchers. 2 disease-modifying antirheumatic drugs, TNF inhibitors and hydroxychloroquine, are associated with a reduced risk for the development of diabetes in psoriasis and rheumatoid arthritis patients

Inform Dual ISH to determine HER2 gene in breast cancer patients
Breast cancer is the second leading cause of cancer-related death among women. About 20 percent of women diagnosed with breast cancer are HER2-positive. The Inform Dual ISH test allows lab personnel to count the number of copies of HER2 genes on chromosome 17 in a small sample of the breast tumor. Copies of the HER2 gene appear black and copies of chromosome 17 appear red. Patients with more than the normal number of copies of the HER2 gene are considered candidates for Herceptin therapy.

Parkinson's patients sing in tune with creative arts therapy
Twice a month a jam session takes place on the third floor of Northwestern Memorial's Prentice Women's Hospital. A diverse group of men and women, ranging in age and ethnicity, gather in a circle with instruments in hand and sing together. This is no ordinary jam band; all its members have Parkinson's disease. They are participating in Creative Arts for Parkinson's, a music and drama therapy program offered through Northwestern's Parkinson's Disease and Movement Disorders Center.

New safety recommendations for high dose 80 mg simvastatin
Patients taking simvastatin 80 mg daily had an increased risk of muscle injury. The risk of muscle injury is highest during the first year of treatment with the 80 mg dose of simvastatin, and is frequently associated with a genetic predisposition for simvastatin-related muscle injury or myopathy.

Radiation improves survival in breast cancer surgery patients
Additional radiation treatment improves disease free survival lessening the chance of cancer recurring in women with early breast cancer who have had breast conserving surgery (lumpectomy), interim results of a new study found. The results will be presented Monday, June_6 at the annual meeting of the American Society of Clinical Oncology.

Supportive of intent of ACO proposed rule, ACP expresses concern
In a 10-page letter addressed to Donald Berwick, administrator of the Centers for Medicare and Medicaid Services, ACP today said: The ACP strongly supports the intent of the proposed rule, and believes that an ACO model has the potential of supporting such important care delivery goals as enhancing quality, efficiency, integration, and patient-centeredness.

Developing possibility of a preventive vaccine against HIV AIDS
The HIV epidemic is the largest in the world and represents one of the most serious public health problems, according to data from the World Health Organization (WHO). Only 30% of the more than 10 million patients in need have the access to the antiretroviral treatment.

Getting stroke patients back on their feet
In the largest stroke rehabilitation study ever conducted in the United States, stroke patients who had physical therapy at home improved their ability to walk just as well as those who were treated in a training program that requires the use of a body-weight supported treadmill device followed by walking practice.

Incivek for hepatitis C infection is approved in US
The U.S. Food and Drug Administration approved Incivek (telaprevir) to treat certain adults with chronic hepatitis C infection. Incivek is used for patients who have either not received interferon-based drug therapy for their infection or who have not responded adequately to prior therapies.

New class of asthma, COPD drugs identified
Researchers in Baltimore have identified new compounds which relax airway muscles and may provide relief from shortness of breath for patients with COPD and asthma.

Advanced stage prostate cancer patients experience 20 year survival rates with surgery
Long-term survival rates for patients with advanced prostate cancer suggest they can be good candidates for surgery, Mayo Clinic researchers have found. Their study found a 20-year survival rate for 80 percent of patients diagnosed with cancer that has potentially spread beyond the prostate, known as cT3 prostate cancer, and treated with radical prostatectomy, or surgery to remove the prostate gland.

Vitamin D deficiency in pneumonia patients risky
A new study published in the journal Respirology reveals that adult patients admitted to the hospital with pneumonia are more likely to die if they have Vitamin D deficiency.

Structured exercise training improves glycemic control in diabetes patients
Implementing structured exercise training, including aerobic, resistance or both, was associated with a greater reduction in hemoglobin A1c levels (a marker of glucose control) for patients with diabetes compared to patients in the control group, and longer weekly exercise duration was also associated with a greater decrease in these levels.

Zytiga approved for late stage prostate cancer
The U.S. Food and Drug Administration approved Zytiga (abiraterone acetate) in combination with prednisone (a steroid) to treat patients with late-stage (metastatic) castration-resistant prostate cancer who have received prior docetaxel (chemotherapy).

Thyroid drug Levothyroxine linked to fractures in older adults
Many older adults may be taking "excessive" doses of drugs for thyroid problems which can lead to an increased risk of fractures, finds a study published on today.

New technique extends cancer fighting cells' potency in melanoma patients
Researchers trained white blood cells to attack tumors tend to fade away quickly when injected into cancer patients.

New class of cancer drugs could work in colon cancers with genetic mutation
A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.

HIV infection may be a risk factor for heart failure
Patients with HIV infection without a prior history of coronary heart disease may be at a higher risk of developing heart failure, according to a report in the Archives of Internal Medicine.

Low health literacy linked to higher rate of death in heart failure patients
An examination of health literacy (such as understanding basic health information) among managed care patients with heart failure, a condition that requires self-management, found that nearly one in five have low health literacy, which was associated with a higher all-cause risk of death.

Evidence based treatments decrease risk of death among heart attack patients
In an analysis of data from a coronary care registry in Sweden, between 1996-2007 there was an increase in the prevalence of use of evidence-based invasive procedures and pharmacological therapies for treatment of a certain type of heart attack, and a decrease in the rate of death at 30 days and one year after a heart attack for these patients.

Activation of biomarker may improve survival among obese patients with colorectal cancer
Among obese patients, activation of the protein biomarker CTNNB1 was associated with better colorectal cancer-specific survival and overall survival, whereas post-diagnosis physical activity was associated with better colorectal cancer-specific survival among patients negative for CTNNB1.

Tai chi may improve quality of life in chronic heart failure patients
Tai chi, the ancient Chinese meditative exercise, may improve quality of life, mood and exercise self-efficacy in chronic heart failure patients, according to research led by a team at Beth Israel Deaconess Medical Center.

Combination therapy provides hope for cure of infections in cystic fibrosis
An over-the-counter drug used to treat diarrhea combined with minocycline, an antibiotic used to treat bacterial infections, could one day change the lives of those living with cystic fibrosis.

Weight loss may improve memory and concentration
John Gunstad, an associate professor in Kent State University's Department of Psychology, and a team of researchers have discovered a link between weight loss and improved memory and concentration. The study shows that bariatric surgery patients exhibited improved memory function 12 weeks after their operations.

QNEXA for Weight Loss in obesity - CONQUER study
VIVUS, Inc. (NASDAQ: VVUS) announced that detailed results from the 56-week CONQUER study were published in The Lancet evaluating the efficacy and safety of investigational drug QNEXA in 2,487 patients across 93 sites in the US.

New treatment with omalizumab may desensitize kids with milk allergies
Milk allergy is the most common, affecting 2.5 percent of children under age 3. In a small clinical study, researchers report effectively desensitizing milk-allergic patients by increasing their exposure to milk in tandem with an allergy drug called omalizumab, allowing children to build up resistance quickly with limited allergic reactions.

HIV infected at higher risk for bone fractures
Low bone mineral density in HIV-infected patients is common and raises concerns about increased risks of fracture, revealed by researchers.

Fetal surgery better in treating children with spina bifida
Thirty years ago, the first human fetal surgery was performed at the University of California, San Francisco. Now, a randomized controlled trial has proven definitively that fetal surgery can help certain patients before birth.

Use of atypical antipsychotics in treatment of dementia declined in US
A warning issued by the Food and Drug Administration regarding the use of atypical antipsychotics for the treatment of dementia was associated with a significant decline in the use of these medications for treating dementia symptoms in elderly patients.

Antipsychotic drugs may lead to brain loss in schizophrenia patients
Patients with schizophrenia who take antipsychotic medications appear to lose a small but measurable amount of brain tissue over time, according to a report in the February issue of Archives of General Psychiatry.

New treatment for severe 2009 H1N1 infection
Convalescent plasma therapy-using plasma from patients who have recovered from an infection to treat those with the same infection-has been used to treat multiple diseases.

Stroke rate rises in HIV patients
While the overall hospitalization rate for stroke has declined in recent years, the numbers have jumped dramatically for patients infected with human immunodeficiency virus (HIV), suggesting they may be up to three times more likely to suffer a stroke than people uninfected by the virus that causes AIDS.

Gene is mutated in 1 in 3 patients with kidney cancer
Researchers have identified a gene that is mutated in one in three patients with the most common form of renal cancer. The identification of a frequently mutated gene will provide new insights into the biology of the disease.

New drug for melanoma skin cancer patients soon
Plexxikon Inc. announced positive data from an interim analysis of the BRIM3 trial, a large multi-center Phase 3 clinical study of PLX4032 (RG7204) in patients with previously untreated metastatic melanoma with the BRAF mutation.

Follow up helps detect melanoma earlier
A follow-up program for patients at high risk of developing skin cancer appears to be associated with the detection of melanomas at early stages and with good prognosis.

Statins not for low risk patients
There is not enough evidence to recommend the widespread use of statins in people with no previous history of heart disease, according to a new Cochrane Systematic Review.

Private room intensive care units associated with lower infection rates
Converting hospital intensive care units (ICUs) to private rooms is associated with a reduction in the rate at which patients acquire infections, according to a report in the January 10 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Statin may raise stroke risk in patients with brain hemorrhage
People with brain hemorrhage - a type of stroke - should avoid taking cholesterol lowering drugs called statins, revealed by researchers in US.

Metabolic syndrome common in psoriasis patients
Individuals with psoriasis have a high prevalence of the metabolic syndrome, according to a report that will appear in the April_2011 print issue of Archives of Dermatology.

Doctors on Facebook may be compromising doctor patient relationship
Doctors with a profile on the social networking site Facebook may be compromising the doctor-patient relationship, because they don't deploy sufficient privacy settings, indicates research published online in the Journal of Medical Ethics.

Medicaid funded ADHD treatment for children is failing
Whatever its final incarnation, the recently enacted landmark Patient Protection and Affordable Care Act will expand Medicaid eligibility and is expected by 2013 to provide coverage, including mental health care, to an estimated 4.1 million children currently uninsured.

Mindfulness meditation effective to prevent depression relapse
A new study from the Centre for Addiction and Mental Health (CAMH) has found that mindfulness-based cognitive therapy--using meditation-provides equivalent protection against depressive relapse as traditional antidepressant medication.

Rheumatoid arthritis increases heart attack risk 60%
The risk of having a heart attack is 60 per cent higher just a year after a patient has been diagnosed with rheumatoid arthritis, according to research published in the December issue of the Journal of Internal Medicine.

International clinical trial tests targeted drug for melanoma skin cancer
Rush University Medical Center has just enrolled the first U.S. patient in an international clinical trial testing a novel drug to treat certain kinds of melanoma, a deadly skin cancer that in its advanced stages currently has few effective treatments.

Celebrex may prevent some non melanoma skin cancers
New research shows the NSAID Celebrex may help prevent some non-melanoma skin cancers from developing in patients who have pre-cancerous actinic keratoses lesions and are at high risk for having the disease.

US company starts clinical trial using stem cells to treat macular degeneration
Advanced Cell Technology, Inc. ("ACT"; OTCBB:ACTC) announced that the US Food and Drug Administration (FDA) has cleared the Company's Investigational New Drug (IND) application to immediately initiate a Phase I/II multicenter clinical trial using retinal cells derived from human embryonic stem cells (hESCs) to treat patients with Stargardt's Macular Dystrophy (SMD), one of the most common forms of juvenile macular degeneration in the world.

Homeopathy consultations can benefit arthritis patients
In a study published in the journal Rheumatology, researchers found that arthritis patients significantly benefited when they received homeopathy alongside conventional treatment over a period of 6 months.

Potential target identified for therapy for prostate cancer
A monoclonal antibody targeting a well known cell surface protein inhibited prostate cancer growth and metastasis in an aggressive form of the disease that did not respond to hormone therapy.

Clinical trial of human embryonic stem cell therapy in US
Geron Corporation (Nasdaq: GERN) announced the enrollment of the first patient in the company's clinical trial of human embryonic stem cell (hESC)-derived oligodendrocyte progenitor cells, GRNOPC1.

Stem cells shape up to their surroundings
Many scientists aspire to take control over the stem cell differentiation process, so that we can grow organs and implants perfectly matched to each patient in the future.

Higher breast density increases breast cancer risk
Researchers at Kaiser Permanente have found that patients with a very early form of breast cancer (ductal carcinoma in situ or DCIS) who have higher mammographic density may be at increased risk for subsequent breast cancer, especially in the breast opposite to the one with the initial cancer.

STD inoculation study in Guatemala was unethical - US
In 1946, a sexually transmitted disease inoculation study was conducted in Guatemala. American scientists infected hundreds of prisoners and patients in a mental hospital in Guatemala with syphilis and other sexually transmitted diseases.

Genetic patterns may predict osteoarthritis
Scientists from University of North Carolina at Chapel Hill School of Medicine and Interleukin Genetics, Inc. announced findings from a large clinical study to evaluate the role played by genetic factors in the worsening of osteoarthritis.

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