Safe - most related articles:

- Consumer Healthcare supports FDA over OTC cough and cold medicines withdrawal - 2.2
- Tenofovir gel safe for daily use - 2.1

Safe articles

Ebola vaccine from Glaxo promising and safe
A 39-year-old woman has become the first volunteer to receive an experimental Ebola vaccine, which scientists have described as "promising".

Anthrax exposure in CDC Lab USA
CDC announced that approximately 75 Atlanta-based staff are being monitored or provided antibiotics because they may have been unintentionally exposed to live Bacillus anthracis (anthrax) after established safety practices were not followed.

Avoid decorative and colored contact lenses this Halloween for eye safety
Decorative and colored contact lenses are extremely popular during Halloween as they enhance the costume. But, be aware that these lenses carry a significant health risk. U.S. Food and Drug Administration is discouraging consumers from using decorative contact lenses.

Arsenic in rice and rice products is low
The levels FDA found in its testing are too low to cause immediate or short-term adverse health effects. FDA's work going forward will center on long-term risk and ways to manage it with a focus on long-term exposure.

Pazopanib better than sunitinib in advanced kidney cancer
Two oral targeted drugs -- Pazopanib (Votrient) and sunitinib (Sutent) -- approved for metastatic kidney cancer worked equally well, but one proved superior in tolerability, the safety profile and many measures of quality of life favored pazopanib.

Prostate cancer - active surveillance and watchful waiting better
Many men with low-risk, localized prostate cancers can safely choose active surveillance or "watchful waiting" instead of undergoing immediate treatment and have better quality of life while reducing health care costs, according to a study by researchers at Dana-Farber Cancer Institute and Massachusetts General Hospital.

Natrelle 410 silicone gel breast implants approved in US
The U.S. Food and Drug Administration approved the Natrelle 410 Highly Cohesive Anatomically Shaped Silicone-Gel Filled Breast Implant to increase breast size (augmentation) in women at least 22 years old and to rebuild breast tissue (reconstruction) in women of any age. Natrelle 410 implants are manufactured by Allergan, Inc.

New US food safety standards for foodborne illness prevention and produce safety
The U.S. Food and Drug Administration proposed two new food safety rules that will help prevent foodborne illness. The proposed rules implement the landmark, bipartisan FDA Food Safety Modernization Act (FSMA) and are available for public comment for the next 120 days.

Hurricane Sandy and food storage and food safety
Hurricane Sandy is already making an impact on the North Eastern coast, and being prepared for a storm as large as this is crucial. Hurricane Sandy could bring wind, flooding, heavy rain and possibly snow to the East Coast, and the U.S. Department of Agriculture's (USDA) Food Safety and Inspection Service (FSIS) urges people to take steps now to ensure they have access to safe food.

Food safety guides available for groups most vulnerable to foodborne illness
The U.S. Department of Agriculture?s Food Safety and Inspection Service (FSIS) and the Department of Health and Human Services? Food and Drug Administration (FDA) have partnered to create six booklets with food safety advice for populations that are most susceptible to foodborne illness.

Antibiotics a safe and viable alternative to surgery for uncomplicated appendicitis
Giving antibiotics to patients with acute uncomplicated appendicitis is a safe and viable alternative to surgery, say experts in a study published in BMJ.

Safety changes in labeling for cholesterol lowering drugs statins
Important safety changes to the labeling for some widely used cholesterol-lowering drugs known as statins are being announced by the U.S. Food and Drug Administration. These products, when used with diet and exercise, help to lower a person's "bad cholesterol (low-density lipoprotein cholesterol).

Surgeons age linked to safe health care
Surgeons aged between 35 and 50 years provide the safest care compared with their younger or older colleagues. The findings raise concerns about ongoing training and motivation of surgeons during their careers.

Malaria during pregnancy first trimester - antimalarial is safe
The malaria disease significantly increases the risk of miscarriage, but that treating with antimalarial drugs is relatively safe and reduces this risk in pregnant women expecting their new born babies.

Heading a soccer ball could lead to brain injury
Frequent 'heading' in soccer can lead to brain injury and cognitive impairment, revealed by researchers. Einstein Montefiore research suggests frequency threshold for injury that could lead to safety guidelines.

4 drugs accounted for two thirds of emergency hospitalizations in US
Handful of drugs are responsible for most emergency room visits by patients in US, revealed by CDC researchers (US Centers for Disease Control and Prevention) in a recent study.

Low risk pregnant women can opt for home birth
A new study reveals that women with low risk pregnancies should be able to choose where they give birth. Although it shows that first-time mums who opt for a home birth are at a higher risk of adverse outcomes, the overall risk is low in all birth settings.

Acne treatment with oral antibiotics may cause sore throat
Taking oral antibiotics for treatment of acne appears to be associated with reporting symptoms of pharyngitis (sore throat). The results are proving many inconsistent concerns true about the safety of long-term use of antibiotics.

Avastin bevacizumab approval revoked to treat breast cancer in US
US health agency FDA Commissioner Margaret A. Hamburg, M.D. has revoked the approval of the breast cancer indication for Avastin (bevacizumab) after concluding that the drug has not been shown to be safe and effective for that use.

35 new drugs approved in 2011 in US
Over the past 12 months, the U.S. Food and Drug Administration approved 35 new medicines for patients, like two new treatments for hepatitis C; a drug for late-stage prostate cancer; the first new drug for Hodgkin's lymphoma in 30 years; and the first new drug for lupus in 50 years.

Pfizer new drug could provide a new treatment option for postmenopausal women
Pfizer Inc. will announce new one-year results from the Selective estrogens, Menopause, And Response to Therapy [SMART]-5 Phase 3 study of the safety and efficacy of the investigational tissue selective estrogen complex (TSEC) bazedoxifene/conjugated estrogens (BZA/CE) at the 22nd annual meeting of the North American Menopause Society (NAMS), September_21-24 in Washington, D.C.

Successful separation of conjoined craniopagus Sudanese twins
Twin girls joined at the head, such that their major brain blood vessels were interconnected, have been safely separated. UK charity Facing the World played the central role in funding treatment, evaluating the children abroad, supporting the family and handling the logistics to bring Rital and Ritag Gaboura and their parents to London.

No cases Salmonella of from recalled ground turkey products in Washington US
No cases of Salmonella Heidelberg associated with recalled ground turkey products have been reported in Washington. Thoroughly cooking and safely handling and preparing meat and poultry will kill bacteria like Salmonella Heidelberg, which prevents illness.

Low body fat may not lower risk for heart disease and diabetes
Researchers revealed that some people with a specific form of the gene are more likely to have lower percent body fat, but also more likely to develop heart disease and type 2 diabetes, because the gene lowers only the "subcutaneous" fat under the skin, but not the more harmful "visceral" fat that surrounds organs. People with this gene variant are less able to store fat safely under the skin and may, therefore, store fat elsewhere in the body, where it may interfere with normal organ function.

IUD following abortion likely to prevent unintended pregnancy
Immediate use of any contraceptive method after abortion has been linked to a reduced risk of repeat abortion with the immediate use of an IUD being the most effective method for reducing the risk for another unintended pregnancy. IUDs are found safe and highly effective.

New safety recommendations for high dose 80 mg simvastatin
Patients taking simvastatin 80 mg daily had an increased risk of muscle injury. The risk of muscle injury is highest during the first year of treatment with the 80 mg dose of simvastatin, and is frequently associated with a genetic predisposition for simvastatin-related muscle injury or myopathy.

A better imaging agent for heart disease and breast cancer
Scientists are reporting development of a process for producing large quantities of a much-needed new imaging agent for computed tomography (CT) scans in heart disease, breast cancer and other diseases, and the first evidence that the material is safe for clinical use.

Nanomedicine closer to reality, Stanford
A class of engineered nanoparticles -- gold-centered spheres smaller than viruses -- has been shown safe when administered by two alternative routes in a mouse study led by investigators at the Stanford University School of Medicine.

Half of all children with autism wander and bolt from safe places
The Interactive Autism Network (IAN), reveals the preliminary results of the first major survey on wandering and elopement among individuals with autism spectrum disorders (ASD), and announces the launch of a new research survey on the association between pregnancy factors and ASD.

QNEXA for Weight Loss in obesity - CONQUER study
VIVUS, Inc. (NASDAQ: VVUS) announced that detailed results from the 56-week CONQUER study were published in The Lancet evaluating the efficacy and safety of investigational drug QNEXA in 2,487 patients across 93 sites in the US.

Warning Letters to caffeinated alcoholic beverages, US
The U.S. Food and Drug Administration warned four companies that the caffeine added to their malt alcoholic beverages is an "unsafe food additive" and said that further action, including seizure of their products, is possible under federal law.

Function found for Alzheimer's protein APP
A new study reveals that when amyloid precursor protein (APP) fails to convert iron from an unsafe form to a safe one for transport or storage, it leads to rise in iron levels inside neurons mount to toxic levels and eventually causes Alzheimer's disease.

Rosiglitazone Avandia diabetes drug should be withdrawn
A BMJ investigation into the top-selling diabetes drug rosiglitazone (Avandia) raises concerns about its safety and the whole system by which drugs are evaluated, regulated, and promoted around the world.

Knowledge gaps in research for 20 suspected carcinogens
A new report from the American Cancer Society and other world-leading health groups identifies gaps in research for 20 suspected carcinogens whose potential to cause cancer is as yet unresolved.

Salsa and guacamole important causes of foodborne disease
Nearly 1 out of every 25 restaurant-associated foodborne outbreaks with identified food sources between 1998 and 2008 can be traced back to contaminated salsa or guacamole, more than double the rate during the previous decade.

Discussing patient safety in radiation therapy
A meeting in Miami this week will bring together some of the world's leading experts from inside and outside the clinic to discuss safety in radiation therapy -- a critical method for treating cancer.

Indoor tanning linked to melanoma
New research from the University of Minnesota's School of Public Health and Masonic Cancer Center definitively links the use of indoor tanning devices to increased risk of melanoma, the most serious form of skin cancer.

Long term use of heartburn drugs linked to fractures
The U.S. Food and Drug Administration warned consumers and health care professionals about a possible increased risk of fractures of the hip, wrist, and spine with high doses or long-term use of a class of medications called proton pump inhibitors.

Use broad spectrum sunscreen to protect against UV rays
Sunscreen active ingredients, which are compounds that absorb, scatter or reflect ultraviolet (UV) light, are regulated as over-the-counter (OTC) drugs by the U.S. Food and Drug Administration (FDA).

Safely reduce BP in patients with diabetes and heart disease
New study revealed that there is an increased risk of heart attack and stroke for patients having blood pressure either too high or too low. Systolic blood pressure above 120 in patients with diabetes and coronary artery disease is safer. Levels between 130 and 140 appear to be the most healthful.

Thimerosal in vaccine cannot cause autism - vaccine court, US
US 'vaccine court' ruled in three separate cases that the mercury containing preservative thiomersal does not cause autism. This ruling supports the broad scientific consensus.

Safety concern for HIV drug combination
The U.S. Food and Drug Administration announced preliminary data suggesting that Invirase (saquinavir) in combination with Norvir (ritonavir) may have potentially important adverse effects on the heart.

FDA reviewing Avandia, rosiglitazone and cardiovascular safety
The U.S. Food and Drug Administration (FDA) is reviewing data, submitted in August 2009, from a large, long-term clinical study on possible risks with the diabetes drug, Avandia (rosiglitazone).

New safety controls for asthma drugs, US
The U.S. Food and Drug Administration announced that drugs in the class of long-acting beta agonists (LABAs) should never be used alone in the treatment of asthma in children or adults.

New safety plan for agents used to treat chemotherapy related anemia
The U.S. Food and Drug Administration today approved a risk management program to inform healthcare providers and their patients about the risks of a class of drugs called Erythropoiesis-Stimulating Agents (ESAs).

Testing gene therapy for Alzheimer's disease
University Hospitals Case Medical Center is one of 12 sites conducting the first Phase 2 clinical trial of a gene therapy for Alzheimer's disease (AD). The study uses a viral-based gene transfer system called CERE-110, which is designed to deliver nerve growth factor (NGF) into the brain.

Metformin safe for patients with heart failure and diabetes
A new study has shown that metformin, a drug often used in the treatment of diabetes mellitus, is safe for use in treating patients who have both diabetes and advanced heart failure.

Airport full body scanners are safe, says ACR
Amid concerns regarding terrorists targeting airliners using weapons less detectable by traditional means, the Transportation Security Administration (TSA) is ramping up deployment of whole body scanners at security checkpoints in U.S. airports.

CT scans radiation raise cancer risk
Radiation doses from common CT procedures vary widely and are higher than generally thought, raising concerns about increased risk for cancer, according to a new study led by UCSF imaging specialists.

Stem cell transplant may reverse sickle cell disease
Results of a preliminary study by scientists at the National Institutes of Health and Johns Hopkins show that "mini" stem cell transplantation may safely reverse severe sickle cell disease in adults.

Soy food lowers breast cancer recurrence
Although there is a concern regarding the safety of soy food consumption among breast cancer survivors, researchers have found that women in China who had breast cancer and a higher intake of soy food had an associated lower risk of death and breast cancer recurrence.

Breast ultrasound can reduce breast biopsies in young women
Targeted breast ultrasound of suspicious areas of the breast, including lumps, is a safe, reliable and cost-effective alternative to invasive biopsies for women under age 40.

Vioxx trial data shows early heart risk
US researchers revealed that the heart complications after taking Vioxx, the nonsteroidal anti-inflammatory drug (rofecoxib), could have been identified nearly four years before its manufacturer Merck pulled the drug from the market.

Safety of pandemic H1N1 vaccines monitored by WHO
WHO estimates that around 80 million doses of pandemic vaccine have been distributed and around 65 million people have been vaccinated. National immunization campaigns began in Australia and the People's Republic of China in late September.

Plastics chemicals - phthalates linked to ADHD symptoms
There is a significant positive association between phthalate exposure and ADHD -- attention deficit hyperactivity disorder, revealed by researchers.

Pregnancy is safe for multiple sclerosis patients
Pregnant women with multiple sclerosis are only slightly more likely to have cesarean deliveries and babies with a poor prenatal growth rate than women who do not have multiple sclerosis (MS), revealed by US researchers.

FDA should ensure food safety measures in US
Most Americans support for measures that would give the Food and Drug Administration (FDA) new authority to ensure the food Americans eat does not make them sick.

Gene therapy may improve vision in congenital blindness LCA
Researchers from the University of Pennsylvania School of Medicine and the Center for Cellular and Molecular Therapeutics at the Children's Hospital of Philadelphia have used gene therapy to safely improve vision in five children and seven adults with a rare form of congenital blindness.

Ryan White HIV AIDS program extended
The U.S. Congress has extended the Ryan White HIV/AIDS Program, helping to ensure that more than half a million low-income, uninsured, or underinsured people living with HIV/AIDS have access to lifesaving care.

Pregnant women should get flu shots
Pregnant women should be sure to get all their flu shots as soon as the vaccines become available this year to protect them against both the seasonal flu and the H1N1 (swine) flu.

New HIV vaccine safe and effective in preventing HIV infection
In an encouraging development, an investigational vaccine regimen has been shown to be well-tolerated and to have a modest effect in preventing HIV infection in a clinical trial involving more than 16,000 adult participants in Thailand.

Making imaging procedures safer for patients
The Radiological Society of North America (RSNA) reaffirmed its commitment to patient safety in responding to a study and accompanying perspective on radiation dose from medical imaging procedures in the New England Journal of Medicine (NEJM).

Prechewed food could transmit HIV
Researchers have uncovered the first cases in which HIV almost certainly was transmitted from mothers or other caregivers to children through pre-chewed food.

Aqua Leisure recalls inflatable baby floats
The U.S. Consumer Product Safety Commission, in cooperation with the firm Aqua-Leisure Industries, of Avon, Mass., announced a voluntary recall of Inflatable Baby Floats product manufactured in China.

Takeda's diabetes drug alogliptin received FDA's objection
US top most health agency FDA has asked Takeda to conduct an additional clinical trial to rule out any adverse effects of alogliptin in relation to heart, that means Takeda needs to conduct a cardiovascular safety trial for alogliptin.

Bariatric surgery relatively safe for weight loss
Advances in bariatric surgery (weight loss surgery) have made this procedure as safe as any routine surgical procedure, as per researchers at Duke University Medical Center.

Hair straightener burns amongst under fives rising, UK
Most parents think of electrical sockets and irons when asked about dangers to young children in the home but, unknown to parents, new and unexpected risks from modern home gadgets such as hair straighteners are posing a growing threat to toddlers' safety.

Improve contact lens safety, says US FDA
The U.S. Food and Drug Administration is taking steps to improve contact lens safety by reminding consumers of the importance of following proper cleaning and storing procedures.

FDA reviewing stimulant medications for ADHD
U.S. Food and Drug Administration (FDA) issues safety communication about an ongoing review of stimulant medications used in children with ADHD (Attention deficit hyperactivity disorder).

Morning sickness drug safe for fetuses
Metoclopramide, a drug approved in the U.S. for nausea, vomiting and heartburn poses no significant risks for the fetus according to a large cohort study published in the June 11 issue of the prestigious New England Journal of Medicine, "The Safety of Metoclopramide Use in the First Trimester of Pregnancy".

1 in 4 surgeons fixing botched permanent filler ops
With recent reports of women suffering complications due to cosmetic fillers, the British Association of Aesthetic Plastic Surgeons unveil survey results detailing their top concerns regarding these popular non-surgical treatments.

Certain drug coated stents may be safe, effective
Stents coated with the drug paclitaxel may be a safe, effective treatment option for coronary artery disease (CAD) patients age 70 and older and shouldn't be withheld due to advanced patient age, according to a study reported in Circulation: Cardiovascular Interventions.

Doctors' concerns about care often not addressed, UK
Hospital doctors are frequently frustrated in attempts to raise concerns about standards of care and push forward ideas, a BMA survey indicates.

Health Net offers tips to let the sun shine in, safely
Health Net Inc. (NYSE:HNT) reminds everyone that it's important to remember that this standout star (SUN) also is responsible for thousands of deaths annually due to skin cancer and heat-related illnesses.

$1 M grants to enhance food and feed safety, US
The U.S. Food and Drug Administration recently enhanced its food and feed protection initiatives with the award of three one-year Food Safety and Security Monitoring grants totaling $1 million to the states of Arkansas, Nebraska, and Wisconsin. The funds support cooperative agreements designed to create a national integrated food safety system through enhanced federal and state collaboration in food emergency response activities.

Obama administration launches food safety working
Responding to President Obama's directive to upgrade the nation's food safety system, the White House Food Safety Working Group, led by Agriculture Secretary Tom Vilsack and Health and Human Services Secretary Kathleen Sebelius, launched a Web site to provide information about the group's activities and progress.

Skin cancer knowledge lacking in people
Pale skinned people who are most at risk of skin cancer are ignoring sun safety advice, according to research released to launch Sun Awareness Week 2009.

Keep swine flu leaflets safe - McGimpsey
Over 800,000 leaflets giving the public important information about swine flu will begin dropping through letter-boxes across Northern Ireland today.

Herpes medication does not reduce HIV transmission risk
A recently completed international multi-center clinical trial has found that acyclovir, a drug widely used as a safe and effective treatment to suppress herpes simplex virus-2 (HSV-2), which is the most common cause of genital herpes, does not reduce the risk of HIV transmission when taken by people infected with both HIV and HSV-2.

Influenza A and safety of pork
In the ongoing spread of influenza A(H1N1), concerns about the possibility of this virus being found in pigs and the safety of pork and pork products have been raised.

Drug eluting stents prove more effective
The Cardiovascular Research Foundation (CRF) announced that its landmark study comparing the safety and efficacy of drug-eluting stents and bare-metal stents was published in The New England Journal of Medicine.

Two New Reports on Health Care Quality, US
At a speech before the AFSCME Nurses Conference Secretary Kathleen Sebelius discussed two new HHS reports on the quality of health care in America and challenged hospitals to work to reduce health care associated infections.

Stop Using Hydroxycut Dietary Supplements for weight loss
The U.S. Food and Drug Administration is warning consumers to immediately stop using Hydroxycut products by Iovate Health Sciences Inc., of Oakville, Ontario and distributed by Iovate Health Sciences USA Inc. of Blasdell, N.Y. Some Hydroxycut products are associated with a number of serious liver injuries. Iovate has agreed to recall Hydroxycut products from the market.

Major advance in stem cell reprogramming technology
In a paper publishing online April 23rd in Cell Stem Cell, a Cell Press journal, Dr. Sheng Ding and colleagues from the Scripps Research Institute in La Jolla, California, report an important step forward in the race to make reprogrammed stem cells that may be better suited for use in clinical settings.

Cervical cancer screening might safely be delayed after HPV vaccine
DNA from human papilloma virus type 16 (HPV16) and HPV type 18 (HPV18) were found in the majority of invasive cervical cancers in New Mexico in the 1980s and 1990s, according to a population-based study published in the March 24 online issue of the Journal of the National Cancer Institute.

Baby care products meet safety standards
Allegations made today that commonly used baby products are somehow contaminated with harmful levels of carcinogenic chemicals are patently false and a shameful and cynical attempt by an activist group to incite and prey upon parental worries and concerns in order to push a political, legislative and legal agenda.

1/3rd Americans lose sleep over economy
One-third of Americans are losing sleep over the state of the U.S. economy and other personal financial concerns, according to a new poll released today by the National Sleep Foundation (NSF).

Health insurance essential for people's health and well being
The evidence shows more clearly than ever that having health insurance is essential for people's health and well-being, and safety-net services are not enough to prevent avoidable illness, worse health outcomes, and premature death, says a new report from the Institute of Medicine.

Private hospitals more safer for pregnant women
For women delivering a single baby at term in Australia, the prevalence of adverse perinatal outcomes is higher in public hospitals than in private hospitals.

Fast food pushes salt consumption to unsafe levels
Results of a new survey show that many fast food meals contain far more salt than the government's recommended daily maximum.

Bisphenol A remain in body even after fasting
A University of Rochester Medical Center study challenges common assumptions about the chemical bisphenol A (BPA), by showing that in some people, surprisingly high levels remain in the body even after fasting for as long as 24 hours.

BMA response to surgeons' survey on junior doctors' hours
Commenting on the publication of the Association of Surgeons in Training (ASiT) report on the impact of the European Working Time Directive (EWTD), Chairman of Council at the BMA, Dr Hamish Meldrum said:

US' best hospitals already on surgical checklist use
Recent hoopla surrounding published research citing the patient safety benefits of surgery checklists would suggest medical experts have stumbled onto a startling new tactic to prevent medical error.

Checklist helps reduce surgical complications
Hospitals in eight cities around the globe have successfully demonstrated that the use of a simple surgical checklist, developed by WHO, during major operations can lower the incidence of surgery-related deaths and complications by one third.

Leptin sensitizing agents may help to lose weight
The discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat tissue, generated headlines and great hopes for an effective treatment for obesity. But hopes dimmed when it was found that obese people are unresponsive to leptin due to development of leptin resistance in the brain. Now, researchers at Children's Hospital Boston report the first agents demonstrated to sensitize the brain to leptin: oral drugs that are already FDA-approved and known to be safe. Findings were published January 7 by the journal Cell Metabolism.

Diet Coke Plus violating US FDA food safety law
The US Food and Drug Administration (FDA) reviewed the label for Diet Coke Plus 20 FL OZ (1.25 PT) 591ml. Based on the review, FDA concluded that this product is in violation of the Federal Food, Drug, and Cosmetic Act (the Act).

Older adults at high risk for drug interactions
At least one in 25 older adults, about 2.2 million people in the United States, take multiple drugs in combinations that can produce a harmful drug-drug interaction, and half of these interactions involve a non-prescription medication, researchers from the University of Chicago Medical Center report in the Dec. 24/31, 2008, issue of JAMA.

Flour linked to Salmonella outbreak in New Zealand
Investigations into the outbreak of Salmonella typhimurium phage type 42 have found one detection of the bacteria in samples of flour taken from the home of one of the affected people.

Later school start times may improve sleep
A study in the Dec. 15 issue of the Journal of Clinical Sleep Medicine shows that after a one-hour delay of school start times, teens increased their average nightly hours of sleep and decreased their "catch-up sleep" on the weekends, and they were involved in fewer auto accidents.

Radiologists diagnose and treat self embedding disorder in teens
Minimally invasive, image-guided treatment is a safe and precise method for removal of self-inflicted foreign objects from the body, according to the first report on "self-embedding disorder," or self-injury and self-inflicted foreign body insertion in adolescents.

International Society for Stem Cell Research releases new guidelines
The International Society for Stem Cell Research (ISSCR), the world's leading professional organization of stem cell researchers, released new guidelines for the responsible development of safe and effective stem cell therapies for patients.

14 drugs identified for off label use
Physicians and policy-makers know that drugs are frequently prescribed to treat certain diseases despite a lack of FDA approval - a practice known as off-label prescribing. Yet they say the problem is so big they don't know how to begin tackling it.

Obese women may have safe pregnancy after weight loss surgery
Obese women who have weight loss surgery before becoming pregnant have a lower risk of pregnancy-related health problems and their children are less likely to be born with complications, according to a new RAND Corporation study.

Presumed consent for organ donation, UK
Given the media coverage of the forthcoming report from the Organ Donation Taskforce on presumed consent, journalists covering this issue over the weekend may find the BMA's briefing paper on presumed consent useful.

Bone marrow transplant can cure sickle cell disease
A unique approach to bone marrow transplantation pioneered in part by a Children's Hospital of Pittsburgh of UPMC physician has proven to be the only safe and effective cure for sickle cell disease, according to a new study.

Health Canada reaffirms safety of BPA use
Announcement by Health Canada regarding completion of its assessment of bisphenol A (BPA) offers reassurance to Canadians that the use of this chemical in the production of epoxy resins in metal food and beverage packaging presents no risk to consumers.

Updated labeling for psoriasis drug Raptiva approved
The U.S. Food and Drug Administration announced labeling changes, including a Boxed Warning, to highlight the risks of life-threatening infections, including progressive multifocal leukoencephalopathy (PML), with the use of Raptiva (efalizumab).

Label updates of oral OTC children's cough and cold medicines
The following statement was issued by Linda Suydam, president of Consumer Healthcare Products Association, USA, on the Voluntary Label Updates to Oral OTC Children's Cough and Cold Medicines.

Free drug samples not safe for children
Free prescription drug samples distributed to children may be unsafe, according to a study by physicians from Cambridge Health Alliance and Hasbro Children's Hospital.

Medicare will not pay for extra care
New US federal regulations to restrict Medicare payments to hospitals for the extra care required to treat patients harmed by certain preventable infections and medical errors go into effect on Wednesday, October 1.

US FDA assessed melamine and melamine compounds in food
The U.S. Food and Drug Administration (FDA) issued the results of its interim safety and risk assessment of melamine and melamine-related compounds in food, including infant formula.

Mammograms read by computers will boost cancer detection
A computer can safely replace a medical expert in a revolutionary way of interpreting a breast X-ray ? according to a Cancer Research UK funded study.

Statins do not increase risk of Lou Gehrig's Disease
A U.S. Food and Drug Administration's analysis provides new evidence that the use of statins does not increase incidence of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease often referred to as "Lou Gehrig's Disease." The analysis was reported on Monday, Sept. 29, 2008 in Pharmacoepidemiology and Drug Safety.

Electronic cigarette not a safe or proven quitting method for smokers
Contrary to what some marketers of the electronic cigarette imply in their advertisements, the World Health Organization (WHO) does not consider it to be a legitimate therapy for smokers trying to quit.

Need to govern organ donation and transplantation
All countries should take steps to govern organ donation and transplantation, thereby ensuring patient safety and prohibiting unethical practices, according to an article appearing in the September 2008 issue of the Clinical Journal of the American Society of Nephrology (CJASN).

Moisturisers may increase skin cancer risk
Moisturisers used by millions of people may be increasing the risk of common skin cancer like melanoma, hinted by researchers. However, the researchers had cautioned that the experiments were carried out on mice, but the majority of moisturisers have not gone through skin cancer safety checks.

Canada inspecting shipments of peppers from Mexico
In keeping with the Government's commitment to food safety, the Canadian Food Inspection Agency (CFIA) is taking precautionary actions to prevent the implicated source of the Salmonella Saintpaul outbreak in the United States (U.S.) from entering Canada.

US Food Protection Plan shows significant progress
The U.S. Food and Drug Administration's Food Protection Plan Progress Report in conjunction with the Interagency Working Group on Import Safety Action Plan Update, shows significant areas of activity to further improve the safety of America's food supply since unveiling its Food Protection Plan in November 2007.

Anti-smoking medicine Chantix banned for pilots
US Federal Aviation Administration ordered pilots and air traffic controllers to stop taking anti-smoking medicine Chantix immediately, as a new study reported that the anti-smoking medicine Chantix might lead to some health problems in its users and finally may lead safety problems during flight.

Oral HRT doubles risk of blood clots
Hormone replacement therapy (HRT) given in skin patches may cause fewer blood clots than HRT given orally, revealed by researchers in British Medical Journal, UK. Women who take the oral form of HRT more than double their risk of developing a blood clot.

Contaminated heparin not given to New Zealand patients
New Zealanders who were given the intravenous medication, heparin, can be reassured contaminated products found overseas have not been supplied to the New Zealand market, reported by Medsafe, New Zealand.

Contaminant identified in tainted Baxter's heparin
An international team of researchers led by Massachusetts institute of technology (MIT) has explained how contaminated batches of the blood-thinner heparin were able to slip past traditional safety screens and kill dozens of patients recently in the United States and Germany.

FDA to establish offices in China
In an important development, the U.S. Food and Drug Administration has received approval from the U.S. State Department to establish eight full time permanent FDA positions at U.S. diplomatic posts in the People's Republic of China, pending authorization from the Chinese government.

BMA launches campaign to safeguard medical training, UK
The British Medical Association (BMA) launches a campaign to alert the UK government to doctors' concerns about the future of medical training. It is calling on doctors and medical students in England to e-mail their MPs about the need for budgets for their training to be ringfenced.

Tussionex cough medicine with hydrocodone warning
The U.S. Food and Drug Administration issued an alert on the safe and correct use of Tussionex Pennkinetic Extended-Release Suspension in response to numerous reports of adverse events--including death--associated with the misuse and inappropriate use of this potent cough medication.

Novartis' Femara protects against breast cancer return
Women may reduce the risk of their breast cancer returning by starting treatment with Femara (letrozole) anywhere from one to seven years after finishing tamoxifen therapy, according to a new analysis published in the Journal of Clinical Oncology.

Lower heart effects from Herceptin breast cancer treatment with chemotherapy
A new pilot study by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) found that breast cancer patients can be treated safely with a "dose-dense" regimen of standard chemotherapy agents and the antibody trastuzumab (Herceptin), a drug that has previously been shown to cause cardiac toxicity.

GSK investigation concludes, says MHRA, UK
The Medicines and Healthcare products Regulatory Agency (MHRA) has concluded its four year investigation into Glaxosmithkline and its antidepressant drug Seroxat. The investigation focused on whether GSK had failed to inform the MHRA of information it had on the safety of Seroxat in under 18's in a timely manner.

Helping older people live safely and independently
Complex interventions such as preventive home visits and community-based care after hospital discharge can help improve physical function and maintain independent living in older people, according to a Bristol University study of more than 90,000 older people published in this week's edition of the Lancet. The authors also advise against withdrawal of existing well-developed services for older people.

Tenofovir gel safe for daily use
A vag inal microbicide that incorporates an antiretroviral (ARV) drug normally used to treat people with HIV is safe for sexually active HIV-negative women to use every day over an extended period, suggest results of a clinical trial of tenofovir topical gel.

Anti HIV gel Tenofovir proven safe for women
An experimental anti HIV gel is safe for women to use on a daily basis, according to researchers at the University of Alabama at Birmingham (UAB) and the University of Pittsburgh School of Medicine.

Anemia drugs for cancer patients raises blood clots risk
Treating anemia with a class of drugs known as erythropoiesis-stimulating agents (ESAs) is associated with an increased risk of venous thromboembolism (blood clots in the deep veins of the legs or in the lungs) and death among patients with cancer, according to an article in the February 27 issue of JAMA.

Global meet on microbicides begins in India
The 4-day biannual International Microbicides 2008 Conference was inaugurated yesterday by the Indian Minister for Health & Family Welfare, Dr. Anbumani Ramadoss. Congratulating the Indian Council for Medical Research (ICMR) for organizing this important international event, the Minister particularly emphasized the need for an active participation and collaboration amongst all stakeholders in achieving the goal of developing a safe, effective, and accessible microbicide for a woman more than a man to deal with behavioral change.

Safer effective way to treat Crohn's disease
A new study established the new alternative strategy, called "top-down" therapy, to treat the patients with Crohn's disease by employing early use of immune-suppressing drugs combined with an antibody without using steroids.

New Zealand's health system needs uplift
Comments from the Health and Disability Commissioner about the safety of New Zealand's hospitals need to be acted on urgently, says the New Zealand Medical Association. Commissioner Ron Paterson told Parliament that New Zealand hospitals are unsafe and the health system lacks national leadership.

Improving the safety testing of chemicals
Testing the safety of chemicals ranging from pesticides to household cleaners will benefit from new technologies and a plan for collaboration, according to federal scientists from the National Institutes of Health (NIH) and the U.S. Environmental Protection Agency (EPA), who announced a new toxicity testing agreement.

Part of ACCORD study halted due to safety concerns
Canadian Diabetes Association has issued its position statement regarding safety concerns of diabetes treatment in ACCORD study - "It is important that people with diabetes not make any changes to their treatments or adjust their blood glucose targets without speaking to their healthcare team".

Botox cosmetic alternatives for wrinkles
Facial plastic surgeon Dr. D.J. Verret of Innovations Facial Plastic Surgery, Texas, USA, reported certain botox alternatives like temporary fillers such as hyaluronic acid can erase the lines by filling in the depression, or Surgiwire procedure can repair skin wrinkles and lines.

21% errors in pathology reports in Miramichi Hospital, New Brunswick
An additional review of pathology reports in Miramichi Hospital, New Brunswick is completed by Dr. Rosemary Henderson, pathologist. This review included 227 cases of prostate and breast cancer biopsies from 2004-2005. The results indicated that 18 percent of the cases had incomplete results and three percent of the cases were misdiagnosed.

DNA sequencing found virus killing transplant recipients in Australia
In the first application of high throughput DNA sequencing technology to investigate an infectious disease outbreak, link the discovery of a new arenavirus to the deaths of three transplant recipients who received organs from a single donor in Victoria, Australia in April 2007.

Adverse reactions linked to Botox use, warns FDA
The U.S. Food and Drug Administration today notified the public that Botox and Botox Cosmetic (Botulinum toxin Type A) and Myobloc (Botulinum toxin Type B) have been linked in some cases to adverse reactions, including respiratory failure and death, following treatment of a variety of conditions using a wide range of doses.

Intensive blood glucose lowering treatment proved fatal for diabetes patients
Intensive blood glucose lowering treatment proved fatal for diabetes patients in a US study, and for Safety, National Heart, Lung, and Blood Institute (NHLBI) has changed intensive blood sugar treatment strategy in clinical trial of diabetes and cardiovascular disease.

Baby personal care products safer for infants
A study published this month in the journal, Pediatrics, suggests that the use of baby lotion, powder, and shampoo is linked to the presence of phthalates in babies. Phthalates are a large family of compounds used in a wide variety of everyday products.

Researchers cracking the code of bird flu time bomb
Researchers at Griffith University Institute for Glycomics, Queensland led by Professor Mark von Itzstein have developed a technique to 'crack-the-code' of the deadly H5N1 avian influenza virus. It will enable influenza virus specialists and drug researchers to interrogate one of the virus' key surface proteins without risk of infection.

Breastfeeding safer for infants of HIV mothers with Nevirapine
An antiretroviral drug already in widespread use in the developing world to prevent the transmission of HIV from infected mothers to their newborns during childbirth has also been found to substantially cut the risk of subsequent HIV transmission during breast-feeding.

UK doctors have no confidence in NHS database
Nine out of ten UK doctors have no confidence in the government's ability to safeguard patient data online, a poll conducted by British Medical Association, BMA News has revealed.

Give your child a smoke-free childhood, says WHO
This year's theme on World Cancer Day is "children and second-hand smoke exposure". Around 700 million children - almost half of the world's children - breathe air polluted by tobacco smoke, particularly at home.

Pfizer's anti smoking Chantix latest safety information
Chantix (varenicline), a prescription medication used to help patients stop smoking reported to have certain adverse effects like changes in behavior, agitation, depressed mood, suicidal ideation, and actual suicidal behavior. US FDA issued a Public Health Advisory to alert health care providers, patients, and caregivers.

Suicidal thoughts and behaviours from epilepsy drugs, alerts Medsafe
Medsafe, New Zealand's Ministry of Health's medicines regulatory arm, is alerting health care professionals in New Zealand about a small increased risk of suicidal thoughts and behaviours in patients taking anti-epileptic medicines.

Vytorin does not appear to be unsafe - American Heart Association
Merck/Schering-Plough Pharmaceuticals released results from the ENHANCE trial, which found that the ezetimibe/simvastatin (Zetia/Zocor) combination drug known as Vytorin was no more effective in reducing artery plaque build-up than simvastatin (Zocor) alone. There were no statistically significant differences in the safety of the drugs, which are used to lower cholesterol.

Oral osteoporosis medicines safe during dental work
Some doctors and dentists had advised patients who take oral osteoporosis medications such as Fosamax and Boniva to postpone dental work, fearing that tooth extractions and other procedures would exacerbate jaw problems purportedly linked to the medication. But the new findings refute the link and suggest the benefits of dentistry likely outweigh the risks for many of these patients.

Protein may trigger insulin production in diabetic patients
If the human body were a stage, then proteins would rank among the lead actors in the play we call "Life." These large biological molecules hold many starring roles, and their lines are dictated by information encoded in our genes. They are production powerhouses, regulating the basic processes of living and controlling countless functions. Many are enzymes that produce or use energy. Others regulate genes.

Compstatin - new drug for vision loss, macular degeneration
University of Florida UF scientists are testing the safety of experimental drug Compstatin for vision loss in macular degeneration patients. In a first-of-its-kind safety research study, University of Florida researchers have injected an anti-inflammatory compound into the eye of a person with a sight-robbing disease.

Exercise improves symptoms in arthritis patients
Patients with arthritis tend to be less fit than their peers who don't have this condition. Studies have shown, however, that they can safely participate in exercise programs to increase their fitness, strength and psychosocial status and that health providers recommend that arthritis patients participate in exercise.

Safety warning on fentanyl skin patch by US FDA
The US Food and Drug Administration issued its second safety warning about the fentanyl transdermal system, an adhesive patch that delivers a potent pain medicine through the skin. In July 2005, the agency issued a similar warning to the public and to health care providers, saying that the directions on the product label and on the patient package insert should be followed exactly in order to avoid overdose.

High protein diet better for weight loss in obese
Presenting the results of the study at the Nutrition Society Conference in Auckland, NZ, CSIRO dietitian Dr Manny Noakes said that the study suggests it is easier than previously thought for men to take action to lose weight.

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