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Ssri articlesParadoxical effect of certain antidepressants discovered
New research helps explain a paradoxical effect of certain antidepressants--that they may actually worsen symptoms before helping patients feel better. These findings may help investigators fix the problem as well as create new classes of drugs to treat depression.Antidepressant may prevent heart failure
A medication usually used to help treat depression and anxiety disorders has the potential to help prevent heart failure. John Tesmer, research professor at the U-M Life Sciences Institute and professor in the Department of Pharmacology at the U-M Medical School, and his research team at the Tesmer lab found that paroxetine, a selective serotonin reuptake inhibitor (SSRI) sold under the name Paxil, inhibits G protein-coupled receptor kinase 2 (GRK2), a protein kinase that becomes over-expressed when people have heart failure.Anti inflammatory drugs reduce effectiveness of SSRI antidepressants
Anti-inflammatory drugs, which include ibuprofen, aspirin and naproxen, reduce the effectiveness of the most widely used class of antidepressant medications, the selective serotonin reuptake inhibitors, or SSRIs, taken for depression and obsessive-compulsive disorder and anxiety disorders.Lack of evidence for antidepressants in Autism
Antidepressants commonly prescribed to people with autistic spectrum disorders cannot be recommended based on current evidence, revealed by Cochrane Researchers.Antidepressant drugs may lead to lactation difficulties in moms
Women taking commonly used forms of antidepressant drugs may experience delayed lactation after giving birth and may need additional support to achieve their breastfeeding goals.Antidepressants may raise stroke risk in postmenopausal women
Women participating in the Women's Health Initiative study who reported taking an antidepressant drug had a small but statistically significant increase in the risk of stroke and of death compared with participants not taking antidepressants.Antidepressant may change personality while relieving symptoms
Individuals taking a medication to treat depression may experience changes in their personality separate from the alleviation of depressive symptoms, according to a report in the December issue of Archives of General Psychiatry, one of the JAMA/Archives journals.Anxious older adults may benefit from antidepressants
Many older adults worry - a lot. Almost one in 10 Americans over age 60 suffer from an anxiety disorder that causes them to worry excessively about normal things - like health, finances, disability and family.
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