Children\'s Hospital Boston health news articles

Local biosurveillance data can improve individual patient care
By taking local biosurveillance data into account when assessing patients for communicable diseases, doctors may be able to make better diagnostic decisions, according to researchers at Children's Hospital Boston. For instance, in the case of strep throat, awareness of local epidemiology at the time of diagnosis could help more than 166,000 people avoid unnecessary antibiotic treatment in the United States every year and catch more than 62,000 missed cases.

EEG can diagnose autism spectrum disorders in infants
A computational physicist and a cognitive neuroscientist at Children's Hospital Boston have come up with the beginnings of a noninvasive test to evaluate an infant's autism risk.

iPhone locates H1N1 swine flu and infectious diseases
A new iPhone application, created by researchers at Children's Hospital Boston in collaboration with the MIT Media Lab, enables users to track and report outbreaks of infectious diseases, such as H1N1 (swine flu), on the ground in real time.

Injection NRG1 may reverse heart attack damage
Researchers at Children's Hospital Boston have laid the groundwork for regenerating heart tissue after a heart attack, in patients with heart failure, or in children with congenital heart defects.

A simple urine dipstick test can diagnose appendicitis now
A protein detectable in urine might serve as a "biomarker" for appendicitis, revealed by researchers at the Proteomics Center at Children's Hospital Boston.

Stem cell protein LIN28 offers a new cancer target
A protein abundant in embryonic stem cells is now shown to be important in cancer, and offers a possible new target for drug development, report researchers from the Stem Cell Program at Children's Hospital Boston.

Down syndrome patients have a reduced risk for cancer
Most cancers are rare in people with Down syndrome, whose overall cancer mortality is below 10 percent of that in the general population.

Embryo's heartbeat drives blood stem cell formation
Biologists have long wondered why the embryonic heart begins beating so early, before the tissues actually need to be infused with blood. Two groups of researchers from Children's Hospital Boston, Brigham and Women's Hospital, and the Harvard Stem Cell Institute (HSCI) -– presenting multiple lines of evidence from zebrafish, mice and mouse embryonic stem cells -– provide an intriguing answer: A beating heart and blood flow are necessary for development of the blood system, which relies on mechanical stresses to cue its formation.

Leptin sensitizing agents may help to lose weight
The discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat tissue, generated headlines and great hopes for an effective treatment for obesity. But hopes dimmed when it was found that obese people are unresponsive to leptin due to development of leptin resistance in the brain. Now, researchers at Children's Hospital Boston report the first agents demonstrated to sensitize the brain to leptin: oral drugs that are already FDA-approved and known to be safe. Findings were published January 7 by the journal Cell Metabolism.

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