Journal of the National Cancer Institute health news articles

Breast cancers found between mammograms more likely to be aggressive
Breast cancers that are first detectable in the interval between screening mammograms are more likely to be aggressive, fast-growing tumors according to a study published online May 3rd in the Journal of the National Cancer Institute.

Hormone therapy at menopause may lead to breast cancer
Hormone therapy around menopause is linked to breast cancer risk, revealed by researchers in a study published in The Journal of the National Cancer Institute.

Body fat distribution linked to ER negative breast cancer
Body fat distribution does not play an important role in the incidence of every subtype of premenopausal breast cancer, but is associated with an increased risk for estrogen receptor (ER)–negative breast cancer.

Brothers of prostate cancer patients undergo more diagnostic activities
The brothers of men with prostate cancer are at an increased risk of prostate cancer diagnosis because of increased diagnostic activity and not necessarily because they carry a genetic mutation that increases risk of the disease, according to a study published online August 19 in The Journal of the National Cancer Institute.

Shark cartilage drug AE-941 does not improve lung cancer survival
The anti-cancer drug AE-941, a shark cartilage derivative, did not improve overall survival in patients with inoperable stage III non-small cell lung cancer, according to a study published online May_26 in the Journal of the National Cancer Institute.

Frequent screening for women over 41 is low after HPV Vaccination
The overall potential benefits of human papillomavirus (HPV) vaccinations or frequent HPV screenings for women over the age of 41 are low, concludes a new study published online February 15 in the Journal of the National Cancer Institute.

Symptoms have little value to diagnose ovarian cancer earlier
Use of symptoms to trigger a medical evaluation for ovarian cancer does not appear to detect early-stage ovarian cancer earlier and would likely result in diagnosis in only 1 out of 100 women in the general population with such symptoms, revealed in an article.

Stressing the benefits of quitting smoking helps smokers
Smokers who received gain-framed messaging from quitline specialists (i.e., stressing the benefits of quitting) had slightly better cessation outcomes than those who received standard-care messaging (i.e., potential losses from smoking and benefits of quitting).

Biomarkers for ovarian cancer rise a year before diagnosis
Concentrations of the biomarkers CA125, human epididymis protein 4 (HE4), and mesothelin began to rise 3 years before clinical diagnosis of ovarian cancer, according to a new study published online December 30 in the Journal of the National Cancer Institute.

Cell phone usage not causing brain tumor
There was no substantial change in brain tumor incidence among adults 5 to 10 years after cell phone usage sharply increased, revealed by researchers.

STD increases prostate cancer risk
Researchers confirmed previous findings that the sexual transmitted infection known as Trichomonas vaginalis is associated with an increased risk of prostate cancer in a study published online September 9 in the Journal of the National Cancer Institute.

High insulin level increases prostate cancer risk
Elevated insulin levels in the normal range appear to be associated with an increased risk of prostate cancer, revealed by researchers in a new study published in the Journal of the National Cancer Institute.

Cetuximab for colorectal cancer with KRAS gene
From a health-care system perspective, it may be more efficient to use the drug cetuximab only in colorectal cancer patients whose tumors have a wild-type KRAS gene, according to a study published online August 7 in the Journal of the National Cancer Institute.

Thalidomide does not improve survival in lung cancer
Treating patients with thalidomide in combination with chemotherapy for small cell lung cancer (SCLC) did not improve their survival but did increase their risk of blood clots, revealed by researchers.

Dietary fat from red meat and dairy linked to pancreatic cancer
High intake of dietary fats from red meat and dairy products was associated with an increased risk of pancreatic cancer, revealed by researchers. This study was undertaken because research relating fat intake to pancreatic cancer was inconclusive.

Cervical cancer screening might safely be delayed after HPV vaccine
DNA from human papilloma virus type 16 (HPV16) and HPV type 18 (HPV18) were found in the majority of invasive cervical cancers in New Mexico in the 1980s and 1990s, according to a population-based study published in the March 24 online issue of the Journal of the National Cancer Institute.

Vitamins C and E and beta carotene may not reduce cancer risk
Women who took beta carotene or vitamin C or E or a combination of the supplements had a similar risk of cancer as women who did not take the supplements, according to data from a randomized controlled trial in the December 30 online issue of the Journal of the National Cancer Institute.

Few DNA repair genes associated with cancer risk
Variants of numerous DNA repair genes initially appeared to be statistically significantly associated with cancer risk in epidemiological studies.

Calcium, vitamin D may not reduce breast cancer risk
Taking calcium and vitamin D supplements does not reduce breast cancer incidence in postmenopausal women, according to data from a randomized, doubled-blind, placebo-controlled trial published online November 11 in the Journal of the National Cancer Institute.

Breast cancer relapse risk low after 5 years
Breast cancer survivors continue to have a substantial risk of disease recurrence after five years of systemic therapy, according to a study published in the August 12 online issue of the Journal of the National Cancer Institute.

Hormone replacement therapy increases breast cancer recurrence
A new study HABITS revealed that breast cancer survivors who took hormone replacement therapy (HRT) for peri- and postmenopausal symptoms increases disease recurrence than those who did not take HRT.

DCIS patients overestimate breast cancer risks
Many women with newly diagnosed DCIS have inaccurate perceptions of the breast cancer risks that they face, and anxiety is particularly associated with these inaccurate perceptions.

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