National Institute of Mental Health health news articles

New experimental drug reduces autism like behaviors
National Institutes of Health researchers have reversed behaviors in mice resembling two of the three core symptoms of autism spectrum disorders (ASD). An experimental compound, called GRN-529, increased social interactions and lessened repetitive self-grooming behavior in a strain of mice that normally display such autism-like behaviors, the researchers say.

Environment factors important than genetic in autism
Shared environmental factors – experiences and exposures common to both twin individuals – accounted for 55% of strict autism and 58% of more broadly defined autism spectrum disorders (ASD), revealed by researchers. Genetic heritability accounted for 37% of autism and 38% of ASD.

50% American children with mental disorders receive professional services
Only about half of American children and teenagers who have certain mental disorders receive professional services, according to a nationally representative survey funded in part by the National Institute of Mental Health (NIMH).

Depression linked to stressful life events rather genes
Stressful life events are strongly associated with a person's risk for major depression, but a certain gene variation long thought to increase risk in conjunction with stressful life events actually may have no effect.

Citalopram ineffective for children with autism
Citalopram, a medication commonly prescribed to children with autism spectrum disorders (ASD), was no more effective than a placebo at reducing repetitive behaviors, according to researchers.

Autism distorts developing brain in children
Individuals with autism spectrum disorders (ASD) tend to stare at people's mouths rather than their eyes.

Past child abuse and genes result in PTSD risk for adults
A traumatic event is much more likely to result in posttraumatic stress disorder (PTSD) in adults who experienced trauma in childhood – but certain gene variations raise the risk considerably if the childhood trauma involved physical or sexual abuse, scientists have found. The research was conducted with funding from the National Institute of Mental Health, which is part of the National Institutes of Health, and others.

Antidepressant and psychotherapy work for depressed teens
Teens with difficult-to-treat depression who do not respond to a first antidepressant medication are more likely to get well if they switch to another antidepressant medication and add psychotherapy rather than just switching to another antidepressant, according to a large, multi-site trial funded by the National Institutes of Health's National Institute of Mental Health (NIMH).

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