Wellcome Trust Sanger Institute health news articles

Cancer treatment with personalised approach to cancer patients
Recently researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. They uncovered hundreds of associations between mutations in cancer genes and sensitivity to anticancer drugs.

Genetic variations transform mild influenza to a life threatening disease
Genetic variations in human body make it more susceptible to diseases. A genetic finding explains why influenza becomes a life-threating disease to some people while it has only mild effects in others.

Gene is mutated in 1 in 3 patients with kidney cancer
Researchers have identified a gene that is mutated in one in three patients with the most common form of renal cancer. The identification of a frequently mutated gene will provide new insights into the biology of the disease.

Genetic variant linked to common migraine
Researchers have produced new insights into the triggers for migraines attacks. They have identified the first-ever genetic risk factor associated with common types of migraine.

New cancer gene UTX identified
Researchers have identified a new cancer gene - one that is common to many cancers and affects the most basic regulation of our genes.

Heart disease mutation carried by 60 million
Heart disease is the number one killer in the world and India carries more than its share of this burden. Moreover, the problem is set to rise: it is predicted that by 2010 India's population will suffer approximately 60% of the world's heart disease.

Brain genes linked to BMI, obesity
A genetic study of more than 90,000 people has identified six new genetic variants that are associated with increased Body Mass Index (BMI), the most commonly used measure of obesity. Five of the genes are known to be active in the brain, suggesting that many genetic variants implicated in obesity might affect behaviour, rather than the chemical processes of energy or fat metabolism.

Second genetic link to obesity
A study of 90,000 people has uncovered new genetic variants that influence fat mass, weight and risk of obesity. The variants act in addition to the recently described variants of the FTO gene: on average, adults carrying variants in both genes are 3.8 kg (or 8.5 lb) heavier.

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