Wellcome Trust health news articles

Cancer treatment with personalised approach to cancer patients
Recently researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. They uncovered hundreds of associations between mutations in cancer genes and sensitivity to anticancer drugs.

Genetic variations transform mild influenza to a life threatening disease
Genetic variations in human body make it more susceptible to diseases. A genetic finding explains why influenza becomes a life-threating disease to some people while it has only mild effects in others.

New malaria vaccine may make all strains of malaria parasite ineffective
A new candidate malaria vaccine with the potential to neutralise all strains of the most deadly species of malaria parasite has been developed by a team led by scientists at the University of Oxford, UK.

Malaria during pregnancy first trimester - antimalarial is safe
The malaria disease significantly increases the risk of miscarriage, but that treating with antimalarial drugs is relatively safe and reduces this risk in pregnant women expecting their new born babies.

HIV drugs may cause premature aging
Researchers revealed that a class of anti-retroviral drugs (NRTIs) commonly used to treat HIV can cause premature ageing, as the drugs damage DNA in the patient's mitochondria. HIV-infected people treated with antiretroviral drugs sometimes show advanced signs of frailty and age-associated diseases such as cardiovascular disease and dementia at an early age.

Gene is mutated in 1 in 3 patients with kidney cancer
Researchers have identified a gene that is mutated in one in three patients with the most common form of renal cancer. The identification of a frequently mutated gene will provide new insights into the biology of the disease.

Genetic variant linked to common migraine
Researchers have produced new insights into the triggers for migraines attacks. They have identified the first-ever genetic risk factor associated with common types of migraine.

Pneumococcal vaccine offers protection to HIV infected
A clinical trial of a vaccine against a major cause of pneumonia and meningitis has shown that it can prevent three out of four cases of re-infection in HIV-infected adults in Africa.

Balancing protein intake may be key to long life
Getting the correct balance of proteins in our diet may be more important for healthy ageing than reducing calories, new research funded by the Wellcome Trust and Research into Ageing suggests.

Artemisinin based anti malarial drugs becoming resistant to malaria
Malaria parasites in western Cambodia have become resistant to artemisinin based therapies, the first-line treatment for malaria, revealed by researchers.

New cancer gene UTX identified
Researchers have identified a new cancer gene - one that is common to many cancers and affects the most basic regulation of our genes.

Heart disease mutation carried by 60 million
Heart disease is the number one killer in the world and India carries more than its share of this burden. Moreover, the problem is set to rise: it is predicted that by 2010 India's population will suffer approximately 60% of the world's heart disease.

New psychotherapy to treat eating disorder
Wellcome Trust researchers have developed a new form of psychotherapy that has been shown to have the potential to treat more than eight out of ten cases of eating disorders in adults, a study out today reports.

Brain genes linked to BMI, obesity
A genetic study of more than 90,000 people has identified six new genetic variants that are associated with increased Body Mass Index (BMI), the most commonly used measure of obesity. Five of the genes are known to be active in the brain, suggesting that many genetic variants implicated in obesity might affect behaviour, rather than the chemical processes of energy or fat metabolism.

21st century could be the age of paranoia
Paranoia is on the increase and could go unchecked unless we take urgent action, claims a leading scientist. Dr Daniel Freeman, a Wellcome Trust fellow, warns that changes in how we live and work could mean that we are entering an "age of paranoia."

Second genetic link to obesity
A study of 90,000 people has uncovered new genetic variants that influence fat mass, weight and risk of obesity. The variants act in addition to the recently described variants of the FTO gene: on average, adults carrying variants in both genes are 3.8 kg (or 8.5 lb) heavier.

International Cancer Genome Consortium sets sights on cancer
The International Cancer Genome Consortium (ICGC), which includes the Wellcome Trust and the Wellcome Trust Sanger Institute in the UK, will generate a valuable resource enabling the development of new and better ways of diagnosing, treating and preventing cancer.

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